Antibody-catalyzed formation of a 14-membered ring lactone

Canadian Journal of Chemistry

Volumn 80, Issue 12, 2002, Pages 1643-1645

  Pungente, Michael D ^a,b   Weiler, Larry ^a   Ziltener, Hermann J ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b LAKEHEAD UNIVERSITY   (Canada)

Author keywords

Catalytic antibodies; Lactones; Macrocyclization

Indexed keywords

CATALYSIS; CHROMATOGRAPHIC ANALYSIS; ENZYMES; ESTERS; MASS SPECTROMETRY;

TRANSESTERIFICATION;

MONOCLONAL ANTIBODIES;

4 NITROPHENOL; ANTIBODY; ENZYME; ESTER DERIVATIVE; ETHER; LACTONE; MONOCLONAL ANTIBODY; PHOSPHONIC ACID DERIVATIVE;

ARTICLE; BINDING AFFINITY; CALCULATION; CATALYSIS; COMPETITIVE INHIBITION; ENZYME SPECIFICITY; EXTRACTION; GAS CHROMATOGRAPHY; MASS SPECTROMETRY; MICHAELIS MENTEN KINETICS; TIME; TRANSESTERIFICATION;

EID: 0036999120     PISSN: 00084042     EISSN: None     Source Type: Journal    
DOI: 10.1139/v02-185     Document Type: Article

References (20)

1. (a) K. Mori and H. Tomioka. Liebigs Ann. Chem. 1001 (1992);
2. (b) M. Lobell and M.P. Schneider. Tet. Asym. 4, 1027 (1993).
3. (a) J.D. Stevenson and N.R. Thomas. Nat. Prod. Rep. 17, 535 (2000);
4. (b) G.A. Nevinsky, D.V. Semenov, and V.N. Buneva. Biochemistry (Mosc), 65, 1233 (2000);
5. (c) C. Rader and B. List. Chem. Eur. J. 6, 2091 (2000);
6. (d) P. Wentworth and K.D. Janda. Curr. Opin. Chem. Biol. 2, 138 (1998);
7. (e) M.M. Mader and P.A. Bartlett. Chem. Rev. 97, 1281 (1997);
8. (f) N.R. Thomas. Nat. Prod. Rep. 13, 479 (1996);
9. (g) S. Paul. Mol. Biotechnol. 5, 197 (1996);
10. (h) A.J. Kirby. Acta. Chem. Scand. 50, 203 (1996);
11. (i) E.M. Driggers and P.G. Schultz. Adv. Protein Chem. 49, 261 (1996);
12. (j) J.R. Jacobsen and P.G. Schultz. Curr. Opin. Struct. Biol. 5, 818 (1995);
13. (k) R.A. Lerner and K.D. Janda. EXS, 73, 121 (1995);
14. (l) D.S. Tawfik, Z. Eshhar, and B.S. Green. Mol. Biotechnol. 1, 87 (1994);
15. (m) H.J. Suzuki. Biochem. 115, 623 (1994).
16. A.D. Napper, S.J. Benkovic, A. Tramontano, and R.A. Lerner. Science (Washington, D.C.), 237, 1041 (1987).
17. M.D. Pungente and L. Weiler. Org. Lett. 3, 643 (2001).
18. J.W. Goding. Monoclonal antibodies: Principles and practices. Academic, New York. 1983. pp. 234-255.
19. E. Harlow and D. Lane. Antibodies: A laboratory manual. Cold Spring Harbor Laboratory, Cold Spring Harbor. 1988. pp. 673.
20. D.S. Clyne, and L. Weiler. Tetrahedron, 55, 13 659 (1999).