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Volumn 29, Issue 6 SUPPL. 18, 2002, Pages 49-53

Pemetrexed in pancreatic cancer

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CYANOCOBALAMIN; DEXAMETHASONE; DIHYDROFOLATE REDUCTASE; FLUOROURACIL; FOLIC ACID; FOLIC ACID ANTAGONIST; GEMCITABINE; PEMETREXED; PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE; THYMIDYLATE SYNTHASE;

EID: 0036981180     PISSN: 00937754     EISSN: None     Source Type: Journal    
DOI: 10.1053/sonc.2002.37472     Document Type: Review
Times cited : (8)

References (19)
  • 2
    • 0032812489 scopus 로고    scopus 로고
    • Pancreaticobiliary cancer: The future aspects of medical oncology
    • van Riel JM, Giaccone G, Pinedo HM: Pancreaticobiliary cancer: The future aspects of medical oncology. Ann Oncol 10:S296-S299, 1999 (suppl 4)
    • (1999) Ann Oncol , vol.10 , Issue.SUPPL. 4
    • Van Riel, J.M.1    Giaccone, G.2    Pinedo, H.M.3
  • 3
    • 0029785693 scopus 로고    scopus 로고
    • New developments in chemotherapy for patients with advanced pancreatic cancer
    • Rothenberg ML: New developments in chemotherapy for patients with advanced pancreatic cancer. Oncology 10:18-22, 1996 (suppl 9)
    • (1996) Oncology , vol.10 , Issue.SUPPL. 9 , pp. 18-22
    • Rothenberg, M.L.1
  • 4
    • 0028292341 scopus 로고
    • Phase II trial of gemcitabine (2′2′ difluorodeoxycytidine) in patients with adenocarcinoma of the pancreas
    • Casper ES, Green MR, Kelsen DP, et al: Phase II trial of gemcitabine (2′2′ difluorodeoxycytidine) in patients with adenocarcinoma of the pancreas. Invest New Drugs 10:29-34, 1994
    • (1994) Invest New Drugs , vol.10 , pp. 29-34
    • Casper, E.S.1    Green, M.R.2    Kelsen, D.P.3
  • 5
    • 8244254377 scopus 로고    scopus 로고
    • Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: A randomized trial
    • Burris HA III, Moore MJ, Andersen J, et al: Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: A randomized trial. J Clin Oncol 15:2403-2413, 1997
    • (1997) J Clin Oncol , vol.15 , pp. 2403-2413
    • Burris H.A. III1    Moore, M.J.2    Andersen, J.3
  • 6
    • 0035165047 scopus 로고    scopus 로고
    • Gemcitabine: Progress in the treatment of pancreatic cancer
    • Heinemann V: Gemcitabine: Progress in the treatment of pancreatic cancer. Oncology 60:8-18, 2001
    • (2001) Oncology , vol.60 , pp. 8-18
    • Heinemann, V.1
  • 7
    • 0032807118 scopus 로고    scopus 로고
    • Experimental drugs and drug combinations in pancreatic cancer
    • Kroep JR, Pinedo HM, van Groeningen CJ, et al: Experimental drugs and drug combinations in pancreatic cancer. Ann Oncol 10:S234-S238, 1999 (suppl 4)
    • (1999) Ann Oncol , vol.10 , Issue.SUPPL. 4
    • Kroep, J.R.1    Pinedo, H.M.2    Van Groeningen, C.J.3
  • 8
    • 0026494947 scopus 로고
    • A dideazatetrahydrofolate analogue lacking a chiral center at C-6, N-[4-[2-(2-amino-3,4-dihydro-4-oxo-7H-pyrrolo[2,3-d]pyrimidin-5-yl) ethyl]benzoyl]-L-glutamic acid, is an inhibitor of thymidylate synthase
    • Taylor EC, Kuhnt D, Shih C, et al: A dideazatetrahydrofolate analogue lacking a chiral center at C-6, N-[4-[2-(2-amino-3,4-dihydro-4-oxo-7H-pyrrolo[2,3-d]pyrimidin-5-yl) ethyl]benzoyl]-L-glutamic acid, is an inhibitor of thymidylate synthase. J Med Chem 35:4450-4454, 1992
    • (1992) J Med Chem , vol.35 , pp. 4450-4454
    • Taylor, E.C.1    Kuhnt, D.2    Shih, C.3
  • 9
    • 0032950347 scopus 로고    scopus 로고
    • Enzyme inhibition, polyglutamation, and the effect of LY231514 (MTA) on purine biosynthesis
    • Mendelsohn LG, Shih C, Chen VJ, et al: Enzyme inhibition, polyglutamation, and the effect of LY231514 (MTA) on purine biosynthesis. Semin Oncol 26:42-47, 1999 (suppl 6)
    • (1999) Semin Oncol , vol.26 , Issue.SUPPL. 6 , pp. 42-47
    • Mendelsohn, L.G.1    Shih, C.2    Chen, V.J.3
  • 10
    • 0030891198 scopus 로고    scopus 로고
    • LY231514 a pyrrlo[2,3-d]pyrimidine based antifolate that inhibits multiple folate requiring enzymes
    • Shih C, Chen VJ, Gossett LS, et al: LY231514 a pyrrlo[2,3-d]pyrimidine based antifolate that inhibits multiple folate requiring enzymes. Cancer Res 57:1116-1123, 1997
    • (1997) Cancer Res , vol.57 , pp. 1116-1123
    • Shih, C.1    Chen, V.J.2    Gossett, L.S.3
  • 11
    • 0032990562 scopus 로고    scopus 로고
    • Activity of the multitargeted antifolate LY 231514 in the human tumor cloning assay
    • Britten CD, Izbicka E, Hilsenbeck S, et al: Activity of the multitargeted antifolate LY231514 in the human tumor cloning assay. Cancer Chemother Pharmacol 44:105-110, 1999
    • (1999) Cancer Chemother Pharmacol , vol.44 , pp. 105-110
    • Britten, C.D.1    Izbicka, E.2    Hilsenbeck, S.3
  • 12
    • 0032859301 scopus 로고    scopus 로고
    • A phase I evaluation of multitargeted antifolate (MTA, LY231514) administered every 21 days, utilizing the modified continual reassessment method for dose escalation
    • Rinaldi DA, Kuhn JG, Burris HA, et al: A phase I evaluation of multitargeted antifolate (MTA, LY231514) administered every 21 days, utilizing the modified continual reassessment method for dose escalation. Cancer Chemother Pharmacol 44:372-380, 1999
    • (1999) Cancer Chemother Pharmacol , vol.44 , pp. 372-380
    • Rinaldi, D.A.1    Kuhn, J.G.2    Burris, H.A.3
  • 13
    • 0033981350 scopus 로고    scopus 로고
    • Phase II study of the multitargeted antifolate LY231514 (AL1MTA, MTA, pemetrexed disodium) in patients with advanced pancreatic cancer
    • Miller KD, Picus J, Blanke C, et al: Phase II study of the multitargeted antifolate LY231514 (AL1MTA, MTA, pemetrexed disodium) in patients with advanced pancreatic cancer. Ann Oncol 11:101-103, 2000
    • (2000) Ann Oncol , vol.11 , pp. 101-103
    • Miller, K.D.1    Picus, J.2    Blanke, C.3
  • 14
    • 0031730802 scopus 로고    scopus 로고
    • Role of folic acid in modulating the toxicity and efficacy of the multitargeted antifolate, LY231514
    • Worzalla JF, Shih C, Schultz RM: Role of folic acid in modulating the toxicity and efficacy of the multitargeted antifolate, LY231514. Anticancer Res 18:3235-3239, 1998
    • (1998) Anticancer Res , vol.18 , pp. 3235-3239
    • Worzalla, J.F.1    Shih, C.2    Schultz, R.M.3
  • 15
    • 0003340561 scopus 로고    scopus 로고
    • Vitamin B12 and folate reduce toxicity of Alimta (pemetrexed disodium, LY231514, MTA), a novel antifolate/antimetabolite
    • abstr 300
    • Bunn P, Paoletti P, Niyikiza C, et al: Vitamin B12 and folate reduce toxicity of Alimta (pemetrexed disodium, LY231514, MTA), a novel antifolate/antimetabolite. Proc Am Soc Clin Oncol 20:76a, 2001 (abstr 300)
    • (2001) Proc Am Soc Clin Oncol , vol.20
    • Bunn, P.1    Paoletti, P.2    Niyikiza, C.3
  • 16
    • 0000006783 scopus 로고    scopus 로고
    • Combination studies with multitargeted antifolate LY231514, MTA, and gemcitabine in advanced solid tumors
    • abstr 79
    • Adjei AA: Combination studies with multitargeted antifolate LY231514, MTA, and gemcitabine in advanced solid tumors. Cancer Invest 18:102-103, 2000 (suppl 1) (abstr 79)
    • (2000) Cancer Invest , vol.18 , Issue.SUPPL. 1 , pp. 102-103
    • Adjei, A.A.1
  • 17
    • 0033993714 scopus 로고    scopus 로고
    • Phase I and pharmacologic study of sequences of gemcitabine and the multitargeted antifolate agent in patients with advanced solid tumors
    • Adjei AA, Erlichman C, Sloan JA, et al: Phase I and pharmacologic study of sequences of gemcitabine and the multitargeted antifolate agent in patients with advanced solid tumors. J Clin Oncol 18:1748-1757, 2000
    • (2000) J Clin Oncol , vol.18 , pp. 1748-1757
    • Adjei, A.A.1    Erlichman, C.2    Sloan, J.A.3
  • 18
    • 0033179374 scopus 로고    scopus 로고
    • Cell cycle modulation by a multitargeted antifolate, LY231514, increases the cytotoxicity and antitumor activity of gemcitabine in HT29 colon carcinoma
    • Tonkinson JL, Worzalla JF, Teng CH, et al: Cell cycle modulation by a multitargeted antifolate, LY231514, increases the cytotoxicity and antitumor activity of gemcitabine in HT29 colon carcinoma. Cancer Res 59:3671-3676, 1999
    • (1999) Cancer Res , vol.59 , pp. 3671-3676
    • Tonkinson, J.L.1    Worzalla, J.F.2    Teng, C.H.3
  • 19
    • 0000539776 scopus 로고    scopus 로고
    • Clinical outcome in patients with advanced pancreatic cancer treated with pemetrexed/gemcitabine
    • abstr 499
    • Kindler HL, Dugan W, Hochster H, et al: Clinical outcome in patients with advanced pancreatic cancer treated with pemetrexed/gemcitabine. Proc Am Soc Clin Oncol 21:125a, 2002 (abstr 499)
    • (2002) Proc Am Soc Clin Oncol , vol.21
    • Kindler, H.L.1    Dugan, W.2    Hochster, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.