메뉴 건너뛰기




Volumn 30, Issue SUPPL. 2, 2002, Pages 85-91

The necessity of biokinetic information in the interpretation of in vitro toxicity data

Author keywords

Biokinetic modelling; In vitro toxicity; Risk assessment strategies

Indexed keywords

VOLATILE AGENT;

EID: 0036975586     PISSN: 02611929     EISSN: None     Source Type: Journal    
DOI: 10.1177/026119290203002s13     Document Type: Conference Paper
Times cited : (34)

References (43)
  • 1
    • 0001880943 scopus 로고
    • Toxicity testing: Strategies and conduct
    • ed. D.B. Clayson, I.C. Munro, P. Shubik & J.A. Seenberg. Amsterdam, The Netherlands: Elsevier
    • Kroes, R. & Feron, V.J. (1990). Toxicity testing: strategies and conduct. In Progress in Predictive Toxicology (ed. D.B. Clayson, I.C. Munro, P. Shubik & J.A. Seenberg), pp. 15-39. Amsterdam, The Netherlands: Elsevier.
    • (1990) Progress in Predictive Toxicology , pp. 15-39
    • Kroes, R.1    Feron, V.J.2
  • 4
    • 12244307923 scopus 로고    scopus 로고
    • EU (1986). Council Directive of 24 November 1986 on the approximation of laws, regulations and administrative provisions of the Member States regarding the protection of animals used for experimental and other purposes (Directive 86/609/EEC). Official Journal of the European Communities L358, 1-29
    • EU (1986). Council Directive of 24 November 1986 on the approximation of laws, regulations and administrative provisions of the Member States regarding the protection of animals used for experimental and other purposes (Directive 86/609/EEC). Official Journal of the European Communities L358, 1-29.
  • 7
    • 0034123724 scopus 로고    scopus 로고
    • Prediction of toxicity from chemical structure
    • Barratt, M.D. (2000). Prediction of toxicity from chemical structure. Cellular and Biological Toxicology 16, 1-13.
    • (2000) Cellular and Biological Toxicology , vol.16 , pp. 1-13
    • Barratt, M.D.1
  • 10
    • 0034825987 scopus 로고    scopus 로고
    • The use of genomics technology to investigate gene expression changes in cultured human liver cells
    • Harries, H.M., Fletcher, S.T., Duggan, C.M. & Baker, V.A. (2001). The use of genomics technology to investigate gene expression changes in cultured human liver cells. Toxicology in Vitro 15, 399-405.
    • (2001) Toxicology in Vitro , vol.15 , pp. 399-405
    • Harries, H.M.1    Fletcher, S.T.2    Duggan, C.M.3    Baker, V.A.4
  • 11
    • 0036311882 scopus 로고    scopus 로고
    • Alternative (non-animal) methods for chemicals testing: Current status and future prospects
    • Worth, A.P. & Balls, M. (2002). Alternative (non-animal) methods for chemicals testing: current status and future prospects. ATLA 30, Suppl. 1, 1-125.
    • (2002) ATLA , vol.30 , Issue.SUPPL. 1 , pp. 1-125
    • Worth, A.P.1    Balls, M.2
  • 12
    • 0020644295 scopus 로고
    • Screening of toxic compounds in mammalian cell cultures
    • Ekwall, B. (1983). Screening of toxic compounds in mammalian cell cultures. Annals of the New York Academy of Sciences 407, 64-77.
    • (1983) Annals of the New York Academy of Sciences , vol.407 , pp. 64-77
    • Ekwall, B.1
  • 13
    • 0029185921 scopus 로고
    • Determinations of critical cellular neurotoxic concentrations in human neuroblastoma (SH-SY5Y) cell cultures
    • Forsby, A., Pilli, F., Bianchi, V. & Walum, E.A. (1995). Determinations of critical cellular neurotoxic concentrations in human neuroblastoma (SH-SY5Y) cell cultures. ATLA 23, 800-811.
    • (1995) ATLA , vol.23 , pp. 800-811
    • Forsby, A.1    Pilli, F.2    Bianchi, V.3    Walum, E.A.4
  • 14
    • 0036298076 scopus 로고    scopus 로고
    • The applicability of in vitro-derived data in hazard identification and characterisation of chemicals
    • Blaauboer, B.J. (2002). The applicability of in vitro-derived data in hazard identification and characterisation of chemicals. Environmental Toxicology and Pharmacology 11, 213-225.
    • (2002) Environmental Toxicology and Pharmacology , vol.11 , pp. 213-225
    • Blaauboer, B.J.1
  • 15
    • 0026766484 scopus 로고
    • Models for the in vitro assessment of neurotoxicity in the nervous system in relation to xenobiotic and neurotrophic factor-mediated events
    • Atterwill, C., Johnston, H. & Thomas, S.M. (1992). Models for the in vitro assessment of neurotoxicity in the nervous system in relation to xenobiotic and neurotrophic factor-mediated events. Neurotoxicology 13, 39-54.
    • (1992) Neurotoxicology , vol.13 , pp. 39-54
    • Atterwill, C.1    Johnston, H.2    Thomas, S.M.3
  • 16
    • 0001815771 scopus 로고
    • In vitro toxicity testing: Purpose, validation and strategy
    • Flint, O.P. (1990). In vitro toxicity testing: purpose, validation and strategy. ATLA 18, 11-18.
    • (1990) ATLA , vol.18 , pp. 11-18
    • Flint, O.P.1
  • 18
    • 0000319985 scopus 로고
    • The use of liver cell cultures derived from different mammalian species in in vitro toxicological studies: Implementation in extrapolation models?
    • Blaauboer, B.J., Wortelboer, H.M. & Mennes, W.C. (1990). The use of liver cell cultures derived from different mammalian species in in vitro toxicological studies: implementation in extrapolation models? ATLA 18, 251-258.
    • (1990) ATLA , vol.18 , pp. 251-258
    • Blaauboer, B.J.1    Wortelboer, H.M.2    Mennes, W.C.3
  • 19
    • 0021279862 scopus 로고
    • A physiologically based description of the inhalation pharmacokinetics of styrene in rats and humans
    • Ramsey, J.C. & Andersen, M.E. (1984). A physiologically based description of the inhalation pharmacokinetics of styrene in rats and humans. Toxicology and Applied Pharmacology 73, 159-175.
    • (1984) Toxicology and Applied Pharmacology , vol.73 , pp. 159-175
    • Ramsey, J.C.1    Andersen, M.E.2
  • 20
    • 0002715928 scopus 로고
    • A multiple dose-route physiological model for volatile chemicals using ACSL/PC
    • ed. F.E. Cellier. San Diego, CA, USA: Society for Computer Simulation
    • Clewell, H.J. & Andersen, M.E. (1986). A multiple dose-route physiological model for volatile chemicals using ACSL/PC. In Languages for Continuous Simulation (ed. F.E. Cellier), pp. 95. San Diego, CA, USA: Society for Computer Simulation.
    • (1986) Languages for Continuous Simulation , pp. 95
    • Clewell, H.J.1    Andersen, M.E.2
  • 22
    • 0025804183 scopus 로고
    • Correlation between oral drug absorption in humans an apparent drug permeability coefficients in human intestinal epithelial (CaCo2) cells
    • Artursson, P. & Karlsson, J. (1991). Correlation between oral drug absorption in humans an apparent drug permeability coefficients in human intestinal epithelial (CaCo2) cells. Biochemical and Biophysical Research Communications 175, 880-885.
    • (1991) Biochemical and Biophysical Research Communications , vol.175 , pp. 880-885
    • Artursson, P.1    Karlsson, J.2
  • 23
    • 0031413702 scopus 로고    scopus 로고
    • Intestinal drug absorption and metabolism in cell cultures: Caco-2 and beyond
    • Artursson, P. & Borchardt, R.T. (1997). Intestinal drug absorption and metabolism in cell cultures: Caco-2 and beyond. Pharmacological Research 14, 1655-1658.
    • (1997) Pharmacological Research , vol.14 , pp. 1655-1658
    • Artursson, P.1    Borchardt, R.T.2
  • 24
    • 0033883959 scopus 로고    scopus 로고
    • Application of a dynamic in vitro gastrointestinal tract model to study the availability of food mutagens, using heterocyclic aromatic amines as model compounds
    • Krul, C., Luiten-Schuite, A., Baandagger, R., Verhagen, H., Mohn, G., Feron, V. & Havenaar, R. (2000). Application of a dynamic in vitro gastrointestinal tract model to study the availability of food mutagens, using heterocyclic aromatic amines as model compounds. Food and Chemical Toxicology 38, 783-792.
    • (2000) Food and Chemical Toxicology , vol.38 , pp. 783-792
    • Krul, C.1    Luiten-Schuite, A.2    Baandagger, R.3    Verhagen, H.4    Mohn, G.5    Feron, V.6    Havenaar, R.7
  • 25
    • 0035286778 scopus 로고    scopus 로고
    • Caco-2 monolayers in experimental and theoretical predictions of drug transport
    • Artursson, P., Palm, K. & Luthman, K. (2001). Caco-2 monolayers in experimental and theoretical predictions of drug transport. Advanced Drug Delivery Reviews 46, 27-43.
    • (2001) Advanced Drug Delivery Reviews , vol.46 , pp. 27-43
    • Artursson, P.1    Palm, K.2    Luthman, K.3
  • 26
    • 0036096659 scopus 로고    scopus 로고
    • Quantitative structure-permeability relationships (QSPRs) for percutaneous absorption
    • Moss, G.P., Dearden, J.C., Patel, H. & Cronin, M.T. (2002). Quantitative structure-permeability relationships (QSPRs) for percutaneous absorption. Toxicology in Vitro 16, 299-317.
    • (2002) Toxicology in Vitro , vol.16 , pp. 299-317
    • Moss, G.P.1    Dearden, J.C.2    Patel, H.3    Cronin, M.T.4
  • 27
    • 0031889726 scopus 로고    scopus 로고
    • An investigation of the mechanism of flux across polydimethylsiloxane membranes by use of quantitative structure-permeability relationships
    • Cronin, M.T., Dearden, J.C., Gupta, R. & Moss, G.P. (1998). An investigation of the mechanism of flux across polydimethylsiloxane membranes by use of quantitative structure-permeability relationships. Journal of Pharmacy and Pharmacology 50, 143-152.
    • (1998) Journal of Pharmacy and Pharmacology , vol.50 , pp. 143-152
    • Cronin, M.T.1    Dearden, J.C.2    Gupta, R.3    Moss, G.P.4
  • 30
    • 0028925028 scopus 로고
    • A biologically-based algorithm for predicting human tissue: Blood partition coefficients of organic chemicals
    • Poulin, P. & Krishnan, K. (1995). A biologically-based algorithm for predicting human tissue: blood partition coefficients of organic chemicals. Human and Experimental Toxicology 14, 273-280.
    • (1995) Human and Experimental Toxicology , vol.14 , pp. 273-280
    • Poulin, P.1    Krishnan, K.2
  • 31
    • 0030052475 scopus 로고    scopus 로고
    • A tissue composition-based algorithm for predicting tissue: Air partition coefficients of organic chemicals
    • Poulin, P. & Krishnan, K. (1996). A tissue composition-based algorithm for predicting tissue: air partition coefficients of organic chemicals. Toxicology and Applied Pharmacology 136, 126-130.
    • (1996) Toxicology and Applied Pharmacology , vol.136 , pp. 126-130
    • Poulin, P.1    Krishnan, K.2
  • 32
    • 0031413080 scopus 로고    scopus 로고
    • A quantitative property-property relationship (QPPR) approach to estimate in vitro tissue-blood partition coefficients of organic chemicals in rats and humans
    • DeJongh, J., Verhaar, H.J. & Hermens, J.L.M. (1997). A quantitative property-property relationship (QPPR) approach to estimate in vitro tissue-blood partition coefficients of organic chemicals in rats and humans. Archives of Toxicology 72, 17-25.
    • (1997) Archives of Toxicology , vol.72 , pp. 17-25
    • DeJongh, J.1    Verhaar, H.J.2    Hermens, J.L.M.3
  • 33
    • 0034659425 scopus 로고    scopus 로고
    • Empirical relations predicting human and rat tissue:air partition coefficients of volatile organic compounds
    • Meulenberg, C.J. & Vijverberg, H.P. (2000). Empirical relations predicting human and rat tissue:air partition coefficients of volatile organic compounds. Toxicology and Applied Pharmacology 165, 206-216.
    • (2000) Toxicology and Applied Pharmacology , vol.165 , pp. 206-216
    • Meulenberg, C.J.1    Vijverberg, H.P.2
  • 35
    • 0344333422 scopus 로고    scopus 로고
    • Prediction of hepatic clearance from microsomes, hepatocytes, and liver slices
    • Houston, J.B. & Carlile, D.J. (1997). Prediction of hepatic clearance from microsomes, hepatocytes, and liver slices. Drug Metabolism Reviews 29, 891-922.
    • (1997) Drug Metabolism Reviews , vol.29 , pp. 891-922
    • Houston, J.B.1    Carlile, D.J.2
  • 37
    • 0029898283 scopus 로고    scopus 로고
    • The use of in vitro cytotoxicity measurements for the prediction of the skin corrosivity potential of acids: A QSAR method
    • Barratt, M.D., Dixit, M.B. & Jones, P.A. (1996). The use of in vitro cytotoxicity measurements for the prediction of the skin corrosivity potential of acids: a QSAR method. Toxicology in Vitro 10, 283-290.
    • (1996) Toxicology in Vitro , vol.10 , pp. 283-290
    • Barratt, M.D.1    Dixit, M.B.2    Jones, P.A.3
  • 39
    • 0032916246 scopus 로고    scopus 로고
    • The integrated use of alternative methods in toxicological risk evaluation. ECVAM Integrated Testing Strategies Task Force Report 1
    • Blaauboer, B.J., Barratt, M.D. & Houston, J.B. (1999). The integrated use of alternative methods in toxicological risk evaluation. ECVAM Integrated Testing Strategies Task Force Report 1. ATLA 27, 229-237.
    • (1999) ATLA , vol.27 , pp. 229-237
    • Blaauboer, B.J.1    Barratt, M.D.2    Houston, J.B.3
  • 41
    • 0002385233 scopus 로고    scopus 로고
    • An integrated approach to the prediction of systemic toxicity using biokinetic models and biological in vitro test methods
    • ed. M. Balls, A-M. van Zeller & M.E. Halder. Amsterdam, The Netherlands: Elsevier
    • Blaauboer, B.J., Forsby, A., Houston, J.B., Beckman, M., Combes, R. D. & DeJongh, J. (2000). An integrated approach to the prediction of systemic toxicity using biokinetic models and biological in vitro test methods. In Progress in the Reduction Refinement and Replacement of Animal Experimentation (ed. M. Balls, A-M. van Zeller & M.E. Halder), pp. 525-536. Amsterdam, The Netherlands: Elsevier.
    • (2000) Progress in the Reduction Refinement and Replacement of Animal Experimentation , pp. 525-536
    • Blaauboer, B.J.1    Forsby, A.2    Houston, J.B.3    Beckman, M.4    Combes, R.D.5    DeJongh, J.6
  • 42
    • 0023751819 scopus 로고
    • Incorporation of in vitro enzyme data into the physiologically-based pharmacokinetic (PBPK) model for methylene chloride: Implications for risk assessment
    • Reitz, R.H., Mendrala, A.L., Park, C.N., Andersen, M.E. & Guengerich, F.P. (1988). Incorporation of in vitro enzyme data into the physiologically-based pharmacokinetic (PBPK) model for methylene chloride: implications for risk assessment. Toxicology Letters 43, 97-116.
    • (1988) Toxicology Letters , vol.43 , pp. 97-116
    • Reitz, R.H.1    Mendrala, A.L.2    Park, C.N.3    Andersen, M.E.4    Guengerich, F.P.5
  • 43
    • 0027207828 scopus 로고
    • Coupling of computer modeling with in vitro methodologies to reduce animal usage in toxicity testing
    • Clewell, H.J., 3rd (1993). Coupling of computer modeling with in vitro methodologies to reduce animal usage in toxicity testing. Toxicology Letters 68, 101-117.
    • (1993) Toxicology Letters , vol.68 , pp. 101-117
    • Clewell H.J. III1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.