Multicolor-FICTION: Expanding the possibilities of combined morphologic, immunophenotypic, and genetic single cell analyses

American Journal of Pathology

Volumn 161, Issue 2, 2002, Pages 413-420

  Martín Subero, José Ignacio ^a,c   Chudoba, Ilse ^b   Harder, Lana ^a   Gesk, Stefan ^a   Grote, Werner ^a   Novo, Francisco Javier ^c   José Calasanz, Maria ^c   Siebert, Reiner ^a  

^a UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^b MetaSystems   (Germany)

^c UNIVERSITY OF NAVARRA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; CARCINOGENESIS; CHILD; CHROMOSOME ABERRATION; CLINICAL ARTICLE; CYTOGENETICS; FLUORESCENCE IN SITU HYBRIDIZATION; GENETIC ANALYSIS; GENOTYPE; HUMAN; IMAGE ANALYSIS; IMMUNOPHENOTYPING; INTERPHASE; KARYOTYPE; LARGE CELL LYMPHOMA; MALE; NONHODGKIN LYMPHOMA; PHENOTYPE; PRIORITY JOURNAL; TECHNIQUE; VALIDATION PROCESS;

EID: 0036966304     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)64197-1     Document Type: Article

References (46)

1. Lindblom A, Liljegren A: Regular review: tumour markers in malignancies. BMJ 2000, 320:424-427
2. Nowell PC, Rowley JD, Knudson AG: Cancer genetics, cytogenetics - defining the enemy within. Nat Med 1998, 4:1107-1111
3. Jaffe ES: Hematopathology: integration of morphologic features and biologic markers for diagnosis. Mod Pathol 1999, 12:109-115
4. Gozzetti A, Le Beau MM: Fluorescence in situ hybridization: uses and limitations. Semin Hematol 2000, 37:320-333
5. Siebert R, Weber-Matthiesen K: Fluorescence in situ hybridization as a diagnostic tool in malignant lymphomas. Histochem Cell Biol 1997, 108:391-402
6. Remstein ED, Kurtin PJ, Buno I, Bailey RJ, Proffitt J, Wyatt WA, Hanson CA, Dewald GW: Diagnostic utility of fluorescence in situ hybridization in mantle-cell lymphoma. Br J Haematol 2000, 110:856-862
7. Squire JA, Thorner P, Marrano P, Parkinson D, Ng YK, Gerrie B, Chilton-Macneill S, Zielenska M: Identification of MYCN copy number heterogeneity by direct FISH analysis of neuroblastoma preparations. Mol Diagn 1996, 1:281-289
8. Kearney L: The impact of the new fish technologies on the cytogenetics of haematological malignancies. Br J Haematol 1999, 104:648-658
9. Weber-Matthiesen K, Winkemann M, Müller-Hermelink A, Schlegelberger B, Grote W: Simultaneous fluorescence immunophenotyping and interphase cytogenetics: a contribution to the characterization of tumor cells. J Histochem Cytochem 1992, 40:171-175
10. Schröck E, du Manoir S, Veldman T, Schoell B, Wienberg J, Ferguson-Smith MA, Ning Y, Ledbetter DH, Bar-Am I, Soenksen D, Garini Y, Ried T: Multicolor spectral karyotyping of human chromosomes. Science 1996, 273:494-497
11. Speicher MR, Gwyn Ballard S, Ward DC: Karyotyping human chromosomes by combinatorial multi-fluor FISH. Nat Genet 1996, 12:368-375
12. Harris NL, Jaffe ES, Stein H, Banks PM, Chan JK, Cleary ML, Delsol G, De Wolf-Peeters C, Falini B, Gatter KC: A revised European-American classification of lymphoid neoplasms: a proposal from the International Lymphoma Study Group. Blood 1994, 84:1361-1392
13. Harris NL, Jaffe ES, Vardiman JW, Stein H, Diebold J, Müller-Hermelink HK, Flandrin G (Eds): WHO classification of haematopoietic and lymphoid tissues: introduction. World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Haemopoietic and Lymphoid Tissues. Lyon, IARC Press, 2001, pp 12-13
14. Willis TG, Dyer MJ: The role of immunoglobulin translocations in the pathogenesis of B-cell malignancies. Blood 2000, 96:808-822
15. Siebert R, Rosenwald A, Staudt LM, Morris SW: Molecular features of B-cell lymphoma Curr Opin Oncol 2001, 13:316-324
16. The Non-Hodgkin's Lymphoma Classification Project: A clinical evaluation of the International Lymphoma Study Group classification of non-Hodgkin's lymphoma. Blood 1997, 89:3909-3918
17. Offit K, Lo Coco FL, Louie DC, Parsa NZ, Leung D, Portlock C, Ye BH, Lista F, Filippa DA, Rosenbaum A, Ladanyi M, Jhanwar S, Dalla-Favera R, Chaganti RSK: Rearrangement of the bcl-6 gene as a prognostic marker in diffuse large-cell lymphoma. N Engl J Med 1994, 331:74-80
18. Drexler HG, Gignac SM, von Wasielewski R, Werner M, Dirks WG: Pathobiology of NPM-ALK and variant fusion genes in anaplastic large cell lymphoma and other lymphomas. Leukemia 2000, 14:1533-1559
19. Falini B, Pulford K, Pucciarini A, Carbone A, De Wolf-Peeters C, Cordell J, Fizzotti M, Santucci A, Pelicci PG, Pileri S, Campo E, Ott G, Delsol G, Mason DY: Lymphomas expressing ALK fusion protein(s) other than NPM-ALK. Blood 1999, 94:3509-3515
20. Mehes G, Luegmayr A, Ambros IM, Ladenstein R, Ambros PF: Combined automatic immunological and molecular cytogenetic analysis allows exact identification and quantification of tumor cells in the bone marrow. Clin Cancer Res 2001, 7:1969-1975
21. Merz H, Lange K, Gaiser T, Müller A, Kapp U, Bittner C, Harder S, Siebert R, Bentz M, Binder T, Diehl V, Feller AC: Characterization of a novel human anaplastic large cell lymphoma cell line tumorigenic in SCID mice. Leuk Lymphoma 2002, 43:165-172
22. Sanchez-Izquierdo D, Siebert R, Harder L, Marugan I, Gozzetti A, Price HP, Gesk S, Hernandez-Rivas JM, Benet I, Sole F, Sonoki T, Le Beau MM, Schlegelberger B, Dyer MJ, Garcia-Conde J, Martinez-Climent JA: Detection of translocations affecting the BCL6 locus in B cell non-Hodgkin's lymphoma by interphase fluorescence in situ hybridization. Leukemia 2001, 15:1475-1484
23. Siebert R, Matthiesen P, Harder S, Zhang Y, Borowski A, Zühlke-Jenisch R, Metzke S, Joos S, Weber-Matthiesen K, Grote W, Schlegelberger B: Application of interphase fluorescence in situ hybridization for the detection of the Burkitt translocation t(8;14)(q24; q32) in B-cell lymphomas. Blood 1998, 91:984-990
24. Rack KA, Delabesse E, Radford-Weiss I, Bourquelot P, Le Guyader G, Vekemans M, Macintyre EA: Simultaneous detection of MYC, BVR1, and PVT1 translocations in lymphoid malignancies by fluorescence in situ hybridization. Genes Chromosom Cancer 1998, 23: 220-226
25. Weber-Matthiesen K, Deerberg-Wittram J, Rosenwald A, Poetsch M, Grote W, Schlegelberger B: Translocation t(2;5) is not a primary event in Hodgkin's disease. Simultaneous immunophenotyping and interphase cytogenetics. Am J Pathol 1996, 149:463-468
26. Wlodarska I, De Wolf-Peeters C, Falini B, Verhoef G, Morris SW, Hagemeijer A, Van den Berghe H: The cryptic inv(2)(p23q35) defines a new molecular genetic subtype of ALK-positive anaplastic large-cell lymphoma. Blood 1998, 92:2688-2695
27. Lengauer C, Green ED, Cremer T: Fluorescence in situ hybridization of YAC clones after Alu-PCR amplification. Genomics 1992, 13:826-828
28. Schlegelberger B, Metzke S, Harder S, Zühlke-Jenisch R, Zhang Y, Siebert R: Classical and molecular cytogenetics of tumor cells. Diagnostic Cytogenetics. Edited by R Wegner. New York, Springer-Verlag, 1999, pp 151-185
29. Chaganti RS, Nanjangud G, Schmidt H, Teruya-Feldstein J: Recurring chromosomal abnormalities in non-Hodgkin's lymphoma: biologic and clinical significance. Semin Hematol 2000, 37:396-411
30. Siebert R, Gesk S, Harder L, Steinemann D, Grote W, Schlegelberger B, Tiemann M, Wlodarska I, Schemmel V: Complex variant translocation t(1;2) with TPM3-ALK fusion due to cryptic ALK gene rearrangement in anaplastic large-cell lymphoma. Blood 1999, 94:3614-3617
31. Martin-Subero JI, Harder L, Gesk S, Schlegelberger B, Grote W, Martinez-Climent JA, Dyer MJ, Novo FJ, Calasanz MJ, Siebert R: Interphase FISH assays for the detection of translocations with breakpoints in immunoglobulin light chain loci. Int J Cancer 2002, 98:470-474
32. Mueller P, Carroll P, Bowers E, Moore II D, Cher M, Presti J, Wessman M, Pallavicini MG: Low frequency epithelial cells in bone marrow aspirates from prostate carcinoma patients are cytogenetically aberrant. Cancer 1998, 83:538-546
33. Litle VR, Warren RS, Moore II D, Pallavicini MG: Molecular cytogenetic analysis of cytokeratin 20-labeled cells in primary tumors and bone marrow aspirates from colorectal carcinoma patients. Cancer 1997, 79:1664-1670
34. Ridolfi RL, Jamehdor MR, Arber JM: HER-2/neu testing in breast carcinoma: a combined immunohistochemical and fluorescence in situ hybridization approach. Mod Pathol 2000, 13:866-873
35. Thomas L, Leyh H, Marberger M, Bombardieri E, Bassi P, Pagano F, Pansadoro V, Sternberg CN, Boccon-Gibod L, Ravery V, Le Guludec D, Meulemans A, Conort P, Ishak L: Multicenter trial of the quantitative BTA TRAK assay in the detection of bladder cancer. Clin Chem 1999, 45:472-477
36. Sokolova IA, Halling KC, Jenkins RB, Burkhardt HM, Meyer RG, Seelig SA, King W: The development of a multitarget, multicolor fluorescence in situ hybridization assay for the detection of urothelial carcinoma in urine. J Mol Diagn 2000, 2:116-123
37. Chen HT, Bhandoola A, Difilippantonio MJ, Zhu J, Brown MJ, Tai X, Rogakou EP, Brotz TM, Bonner WM, Ried T, Nussenzweig A: Response to RAG-mediated V(D)J cleavage by NBS1 and gamma-H2AX. Science 2000, 290:1962-1965
38. Mueller M, Wacker K, Hickey WF, Ringelstein EB, Kiefer R: Colocalization of multiple antigens and specific DNA. A novel method using methyl methacrylate-embedded semithin serial sections and catalyzed reporter deposition. Am J Pathol 2000, 157:1829-1838
39. Roy L, Coullin P, Vitrat N, Hellio R, Debili N, Weinstein J, Bernheim A, Vainchenker W: Asymmetrical segregation of chromosomes with a normal metaphase/anaphase checkpoint in polyploid megakaryocytes. Blood 2001, 97:2238-2247
40. Weber-Matthiesen K, Deerberg J, Müller-Hermelink A, Winkemann M, Schlegelberger B, Grote W: Rationalization of in situ hybridization: testing up to 16 different probes on a single slide. Cancer Genet Cytogenet 1993, 68:91-94
41. Kononen J, Bubendorf L, Kallioniemi A, Barlund M, Schraml P, Leighton S, Torhorst J, Mihatsch MJ, Sauter G, Kallioniemi OP: Tissue microarrays for high-throughput molecular profiling of tumor specimens. Nat Med 1998, 4:844-847
42. Alizadeh AA, Eisen MB, Davis RE, Ma C, Lossos IS, Rosenwald A, Boldrick JC, Sabet H, Tran T, Yu X, Powell JI, Yang L, Marti GE, Moore T, Hudson J Jr., Lu L, Lewis DB, Tibshirani R, Sherlock G, Chan WC, Greiner TC, Weisenburger DD, Armitage JO, Warnke R, Levy R, Wilson W, Grever MR, Byrd JC, Botstein D, Brown PO, Staudt LM: Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Nature 2000, 403:503-511
43. Shipp MA, Ross KN, Tamayo P, Weng AP, Kutok JL, Aguiar RC, Gaasenbeek M, Angelo M, Reich M, Pinkus GS, Ray TS, Koval MA, Last KW, Norton A, Lister TA, Mesirov J, Neuberg DS, Lander ES, Aster JC, Golub TR: Diffuse large B-cell lymphoma outcome prediction by gene-expression profiling and supervised machine learning. Nat Med 2002, 8:68-74
44. Rosenwald A, Alizadeh AA, Widhopf G, Simon R, Davis RE, Yu X, Yang L, Pickeral OK, Rassenti LZ, Powell J, Botstein D, Byrd JC, Grever MR, Cheson BD, Chiorazzi N, Wilson WH, Kipps TJ, Brown PO, Staudt LM: Relation of gene expression phenotype to immunoglobulin mutation genotype in B cell chronic lymphocytic leukemia. J Exp Med 2001, 194:1639-1647
45. Klein U, Tu Y, Stolovitzky GA, Mattioli M, Cattoretti G, Husson H, Freedman A, Inghirami G, Cro L, Baldini L, Neri A, Califano A, Dalla-Favera R: Gene expression profiling of B cell chronic lymphocytic leukemia reveals a homogeneous phenotype related to memory B cells. J Exp Med 2001, 194:1625-1638
46. Hamblin TJ, Davis Z, Gardiner A, Oscier DG, Stevenson FK: Unmutated Ig V(H) genes are associated with a more aggressive form of chronic lymphocytic leukemia. Blood 1999, 94:1848-1854