Type I insulin-like growth factor receptor expression on colorectal adenocarcinoma cell lines is decreased in response to the chemopreventive agent N-acetyl-L-cysteine

Annals of the New York Academy of Sciences

Volumn 973, Issue , 2002, Pages 555-558

  Kelly, Raymond G ^b   Nally, Kenneth ^b   Shanahan, Fergus ^b   O'Connell, Joe ^a  

^a University College Cork and INFANT Centre   (Ireland)

^b NONE

Author keywords

Colon; Epithelial cells; N Acetyl L cysteine (NAC); Type I insulin like growth factor receptor (IGF IR)

Indexed keywords

ACETYLCYSTEINE; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR;

ADENOCARCINOMA; CANCER CELL; CELL LINE; CHEMOPROPHYLAXIS; COLORECTAL CARCINOMA; CONFERENCE PAPER; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; HUMAN; HUMAN CELL; PROTEIN EXPRESSION;

EID: 0036961941     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2002.tb04700.x     Document Type: Conference Paper

References (5)

1. YU, H. & T. ROHAN. 2000. Role of the insulin-like growth factor family in cancer development and progression. J. Natl. Cancer Inst. 92: 1472-1489.
2. BRODT, P., A. SAMANI & R. NAVAB. 2000. Inhibition of the type I insulin-like growth factor receptor expression and signaling: novel strategies for antimetastatic therapy. Biochem. Pharmacol. 60: 1101-1107.
3. ALBINI, A., M. MORINI, F. D'AGOSTINI, et al. 2001. Inhibition of angiogenesis-driven Kaposi's sarcoma tumor growth in nude mice by oral N-acetylcysteine. Cancer Res. 61: 8171-8178.
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5. 1 prolongation by the chemopreventive agent N-acetylcysteine. Carcinogenesis 20: 1869-1872.