Unlocking the mysteries of virus-host interactions: Does functional genomics hold the key?

Annals of the New York Academy of Sciences

Volumn 975, Issue , 2002, Pages 160-168

  Korth, Marcus J ^a   Katze, Michael G ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Hepatitis C virus; Influenza virus; Microarray; Proteomics; Simian immunodeficiency virus

Indexed keywords

CYTOKINE; INTERFERON;

BIOTECHNOLOGY; CELL SURVIVAL; COMPLEX FORMATION; CONFERENCE PAPER; CYTOKINE PRODUCTION; DATA BASE; GENE EXPRESSION REGULATION; GENOMICS; HEPATITIS C VIRUS; HUMAN IMMUNODEFICIENCY VIRUS; INFLUENZA VIRUS; NONHUMAN; PROTEOMICS; RNA ANALYSIS; SIMIAN IMMUNODEFICIENCY VIRUS; STRESS; VIRUS CELL INTERACTION;

HEPATITIS C VIRUS; HUMAN IMMUNODEFICIENCY VIRUS; INFLUENZA VIRUS; RNA VIRUSES; SIMIAE; SIMIAN IMMUNODEFICIENCY VIRUS;

EID: 0036960130     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2002.tb05949.x     Document Type: Conference Paper

References (12)

1. GEISS, G.K., M.C. AN, R.E. BUMGARNER, et al. 2001. Global impact of influenza virus on cellular pathways is mediated by both replication-dependent and -independent events. J. Virol. 75: 4321-4331.
2. GEISS, G.K., M. SALVATORE, T.M. TUMPEY, et al. 2002. Cellular transcriptional profiling in influenza A virus infected lung epithelial cells: the role of the nonstructural NS1 protein in the evasion of the host innate defense and its potential contribution to pandemic influenza. Proc. Natl. Acad. Sci. USA. 99: 10736-10741.
3. GARCÍA-SASTRE, A., A. EGOROV, D. MATASSOV, et al. 1999. Influenza A virus lacking the NS1 gene replicates in interferon-deficient systems. Virology 252: 324-330.
4. BASLER, C.F., A.H. REID, J.K. DYBING, et al. 2001. Sequence of the 1918 pandemic influenza virus nonstructural gene (NS) segment and characterization of recombinant viruses bearing the 1918 NS genes. Proc. Natl. Acad. Sci. USA 98: 2746-2751.
5. PARK, Y.-W., J. WILUSZ & M.G. KATZE. 1999. Regulation of eukaryotic protein synthesis: selective influenza viral mRNA translation is mediated by the cellular RNA-binding protein GRSF-1. Proc. Natl. Acad. Sci. USA 96: 6694-6699.
6. GALE, M., JR., M.J. KORTH, N.M. TANG, et al. 1997. Evidence that hepatitis C virus resistance to interferon is mediated through repression of the PKR protein kinase by the nonstructural 5A protein. Virology 230: 217-227.
7. TAN, S.-L., H. NAKAO, Y. HE, et al. 1999. NS5A, a nonstructural protein of hepatitis C virus, binds growth factor receptor-bound protein 2 adaptor protein in a Src homology 3 domain/ligand-dependent manner and perturbs mitogenic signaling. Proc. Natl. Acad. Sci. USA 96: 5533-5538.
8. LOHMANN, V., F. KÖRNER, J.-O. KOCH, et al. 1999. Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line. Science 285: 110-113.
9. SHUHART, M.C., M.P. BRONNER, D.R. GRETCH, et al. 1997. Histological and clinical outcome after liver transplantation for hepatitis C. Hepatology 26: 1646-1652.
10. BRAZMA, A., P. HINGAMP, J. QUACKENBUSH, et al. 2001. Minimum information about a microarray experiment (MIAME) toward standards for microarray data. Nature Genet. 29: 365-371.
11. GEISS, G.K., R.E. BUMGARNER, M. AN, et al. 2000. Large-scale monitoring of host cell gene expression during HIV-1 infection using cDNA microarrays. Virology 266: 8-16.
12. GYGI, S.P., B. RIST, S.A. GERBER, et al. 1999. Quantitative analysis of complex protein mixtures using isotope-coded affinity tags. Nature Biotechnol. 17: 994-999.