-
1
-
-
0344073862
-
A randomized, double-blind, placebo-controlled, study using PEG-rhuMGDF as an adjunct to chemotherapy for adults with de-novo acute leukemia: Early results
-
Archimbaud E, Ottman O, Liu Yin J A et al. (1996) A randomized, double-blind, placebo-controlled, study using PEG-rhuMGDF as an adjunct to chemotherapy for adults with de-novo acute leukemia: Early results. Blood 88 [Suppl 1]:447a
-
(1996)
Blood
, vol.88
, Issue.SUPPL. 1
-
-
Archimbaud, E.1
Ottman, O.2
Liu Yin, J.A.3
-
2
-
-
0028224769
-
Growth analysis of marrow CD34-positive hematopoietic progenitor cells in patients with myelodysplastic syndromes
-
Asano H, Hotta T, Ichihara M, Murate T, Kobayashi M, Saito H (1994) Growth analysis of marrow CD34-positive hematopoietic progenitor cells in patients with myelodysplastic syndromes. Leukemia 8:833-838
-
(1994)
Leukemia
, vol.8
, pp. 833-838
-
-
Asano, H.1
Hotta, T.2
Ichihara, M.3
Murate, T.4
Kobayashi, M.5
Saito, H.6
-
3
-
-
10344235968
-
Thrombopoietic effects of pegylated recombinant human megakaryocyte growth and development factor (PEG-rHuMGDF) in patients with advanced cancer
-
Basser R, Rasko JEJ, Clarke K, Cebon J, Green MD, Hussein S, Alt C, Menchaca D, Tomita D, Marty J, Fox RM, Begley CG (1996) Thrombopoietic effects of pegylated recombinant human megakaryocyte growth and development factor (PEG-rHuMGDF) in patients with advanced cancer. Lancet 348:1279-1281
-
(1996)
Lancet
, vol.348
, pp. 1279-1281
-
-
Basser, R.1
Rasko, J.E.J.2
Clarke, K.3
Cebon, J.4
Green, M.D.5
Hussein, S.6
Alt, C.7
Menchaca, D.8
Tomita, D.9
Marty, J.10
Fox, R.M.11
Begley, C.G.12
-
4
-
-
0019952276
-
The French-American-British (FAB) Cooperative Group Proposals for the classification of the myelodysplastic syndromes
-
Bennett JM, Catovsky D, Flandrin G, Galton DAG, Gralnick HR, Sultan C, The French-American-British (FAB) Cooperative Group (1982) Proposals for the classification of the myelodysplastic syndromes. Br J Haematol 51:189-199
-
(1982)
Br. J. Haematol.
, vol.51
, pp. 189-199
-
-
Bennett, J.M.1
Catovsky, D.2
Flandrin, G.3
Galton, D.A.G.4
Gralnick, H.R.5
Sultan, C.6
-
5
-
-
0003261863
-
Safety and biologic effect of pegylated recombinant human megakaryocyte growth and development factor (PEG-rHuMGDF) in breast cancer patients following autologeous peripheral blood progenitor cell transplantation
-
Bolwell B, Vredenburgh J, Overmoyer B, Gilbert C, Chap L, Menchaca D, Scarlata D, Glaspy J (1997) Safety and biologic effect of pegylated recombinant human megakaryocyte growth and development factor (PEG-rHuMGDF) in breast cancer patients following autologeous peripheral blood progenitor cell transplantation. Blood 90 [Suppl 1]:171a
-
(1997)
Blood
, vol.90
, Issue.SUPPL. 1
-
-
Bolwell, B.1
Vredenburgh, J.2
Overmoyer, B.3
Gilbert, C.4
Chap, L.5
Menchaca, D.6
Scarlata, D.7
Glaspy, J.8
-
6
-
-
0028302409
-
Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-MPL ligand
-
De Sauvage FJ, Hass PE, Spencer SD, Malloy BE, Gurney AL, Spencer SA, Darbonne WC, Henzel WJ, Wong SC, Kuang W-J, Oles KJ, Hultgren B, Solberg LA, Goeddel DV, Eaton DL (1994): Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-MPL ligand. Nature 369:533-538
-
(1994)
Nature
, vol.369
, pp. 533-538
-
-
De Sauvage, F.J.1
Hass, P.E.2
Spencer, S.D.3
Malloy, B.E.4
Gurney, A.L.5
Spencer, S.A.6
Darbonne, W.C.7
Henzel, W.J.8
Wong, S.C.9
Kuang, W.-J.10
Oles, K.J.11
Hultgren, B.12
Solberg, L.A.13
Goeddel, D.V.14
Eaton, D.L.15
-
7
-
-
0032228104
-
Peptide agonists of the thrombopoietin receptor
-
Dower WJ, Cwirla SE, Balasubramanian P, Schatz PJ, Baccanaria DP, Barrett RW (1998) Peptide agonists of the thrombopoietin receptor. Stem Cells 16 [Suppl 2]: 21-29
-
(1998)
Stem Cells
, vol.16
, Issue.SUPPL. 2
, pp. 21-29
-
-
Dower, W.J.1
Cwirla, S.E.2
Balasubramanian, P.3
Schatz, P.J.4
Baccanaria, D.P.5
Barrett, R.W.6
-
8
-
-
0031049879
-
Effects of polyethylene glycol-conjugated recombinant human megakaryocyte growth and development factor on platelet counts after chemotherapy for lung cancer
-
Fanucchi M, Glaspy J, Crawford J, Garst J, Figlin R, Sheridan W, Menchaca D, Tomita D, Ozer H, Harker L (1997) Effects of polyethylene glycol-conjugated recombinant human megakaryocyte growth and development factor on platelet counts after chemotherapy for lung cancer. New Engl J Med 336:404-409
-
(1997)
New Engl. J. Med.
, vol.336
, pp. 404-409
-
-
Fanucchi, M.1
Glaspy, J.2
Crawford, J.3
Garst, J.4
Figlin, R.5
Sheridan, W.6
Menchaca, D.7
Tomita, D.8
Ozer, H.9
Harker, L.10
-
9
-
-
0029294859
-
Hematopoietic factors in the treatment of the myelodysplastic syndromes
-
Ganser A (1995) Hematopoietic factors in the treatment of the myelodysplastic syndromes. Curr Opin Hematol 2:204-209
-
(1995)
Curr. Opin. Hematol.
, vol.2
, pp. 204-209
-
-
Ganser, A.1
-
11
-
-
0030018827
-
Clinical use of hematopoietic growth factors in the myelodysplastic syndromes
-
Ganser A, Hoelzer D (1996) Clinical use of hematopoietic growth factors in the myelodysplastic syndromes. Semin Hematol 33:186-195
-
(1996)
Semin. Hematol.
, vol.33
, pp. 186-195
-
-
Ganser, A.1
Hoelzer, D.2
-
12
-
-
0031462140
-
Clinical use of hematopoietic growth factors in the myelodysplastic syndromes
-
Ganser A, Karthaus M (1997) Clinical use of hematopoietic growth factors in the myelodysplastic syndromes. Leuk Lymphoma 26 [Suppl 1]:13-27
-
(1997)
Leuk. Lymphoma
, vol.26
, Issue.SUPPL. 1
, pp. 13-27
-
-
Ganser, A.1
Karthaus, M.2
-
13
-
-
0000162203
-
Recombinant human megakaryocyte growth and development factor augments mobilization of hematopoietic progenitor cells post chemotherapy in patients with acute myeloid leukemia
-
Geissler K, Kabrna E, Stengg S, Schwarzinger I, Knöbl P, Valent P, Eichinger S, Barge A, Lechner K (1997) Recombinant human megakaryocyte growth and development factor augments mobilization of hematopoietic progenitor cells post chemotherapy in patients with acute myeloid leukemia. Blood 90 [Suppl 1]:98a
-
(1997)
Blood
, vol.90
, Issue.SUPPL. 1
-
-
Geissler, K.1
Kabrna, E.2
Stengg, S.3
Schwarzinger, I.4
Knöbl, P.5
Valent, P.6
Eichinger, S.7
Barge, A.8
Lechner, K.9
-
14
-
-
0001690215
-
Effects of pegylated recombinant human megakaryocyte growth and development factor (PEG-rHuMGDF) before high dose chemotherapy (HDC) with peripheral blood progenitor cell transplantation (PBPC)
-
Glaspy J, Vredenburgh J, Demetri GD, Chap L, Gilbert C, Overmoyer B, Warren DL, Berg R, Scarlata D, Menchaca D, Bolwell B (1997) Effects of pegylated recombinant human megakaryocyte growth and development factor (PEG-rHuMGDF) before high dose chemotherapy (HDC) with peripheral blood progenitor cell transplantation (PBPC). Blood 90 [Suppl 1]:580a
-
(1997)
Blood
, vol.90
, Issue.SUPPL. 1
-
-
Glaspy, J.1
Vredenburgh, J.2
Demetri, G.D.3
Chap, L.4
Gilbert, C.5
Overmoyer, B.6
Warren, D.L.7
Berg, R.8
Scarlata, D.9
Menchaca, D.10
Bolwell, B.11
-
15
-
-
0012631510
-
Treating the anemia of MDS with erythropoietin+G-CSF
-
Hellström-Lindberg E (2001) Treating the anemia of MDS with erythropoietin+G-CSF. Leuk Res 25 [Suppl 1]:8
-
(2001)
Leuk. Res.
, vol.25
, Issue.SUPPL. 1
, pp. 8
-
-
Hellström-Lindberg, E.1
-
16
-
-
0030682515
-
Erythroid response to treatment with G-CSF plus erythropoietin for anemia of patients with myelodysplastic syndromes: Proposal for a predictive model
-
Hellström-Lindberg E, Negrin R, Stein R, Krantz S, Lindberg G, Vardiman J, Öst A, Greenberg P (1997) Erythroid response to treatment with G-CSF plus erythropoietin for anemia of patients with myelodysplastic syndromes: proposal for a predictive model. Br J Haematol 99:344-351
-
(1997)
Br. J. Haematol.
, vol.99
, pp. 344-351
-
-
Hellström-Lindberg, E.1
Negrin, R.2
Stein, R.3
Krantz, S.4
Lindberg, G.5
Vardiman, J.6
Öst, A.7
Greenberg, P.8
-
17
-
-
0033018375
-
Characterization of defective megakaryocytic development in patients with myelodysplastic syndromes
-
Hofmann WK, Kalina U, Wagner S, Seipelt G, Ries C, Hoelzer D, Ottmann OG (1999) Characterization of defective megakaryocytic development in patients with myelodysplastic syndromes. Exp Hematol 27:395-400
-
(1999)
Exp. Hematol.
, vol.27
, pp. 395-400
-
-
Hofmann, W.K.1
Kalina, U.2
Wagner, S.3
Seipelt, G.4
Ries, C.5
Hoelzer, D.6
Ottmann, O.G.7
-
18
-
-
0022365867
-
Myelodysplastic syndromes: Pathogenesis, functional abnormalities, and clinical implications
-
Jacobs A (1985) Myelodysplastic syndromes: pathogenesis, functional abnormalities, and clinical implications. J Clin Pathol 38:1201-1217
-
(1985)
J. Clin. Pathol.
, vol.38
, pp. 1201-1217
-
-
Jacobs, A.1
-
19
-
-
0033797720
-
Alteration of c-mpl-mediated signal transduction in CD 34(+) cells from patients with myelodysplastic syndromes
-
Kalina U, Hofmann W, Koschmieder S, Wagner S, Kauschat D, Hoelzer D, Ottmann OG (2000) Alteration of c-mpl-mediated signal transduction in CD 34(+) cells from patients with myelodysplastic syndromes. Exp Hematol 28:1158-1163
-
(2000)
Exp. Hematol.
, vol.28
, pp. 1158-1163
-
-
Kalina, U.1
Hofmann, W.2
Koschmieder, S.3
Wagner, S.4
Kauschat, D.5
Hoelzer, D.6
Ottmann, O.G.7
-
21
-
-
0003868165
-
Experimental design procedures for the behavioral sciences
-
Brooks/Cole, Belmont
-
Kirk SRE (1968) Experimental design procedures for the behavioral sciences. Brooks/Cole, Belmont
-
(1968)
-
-
Kirk, S.R.E.1
-
22
-
-
0000643946
-
Treatment of platelet (PLT) donors with pegylated recombinant human megakaryocyte growth and development factor (PEG-rHuMGDF) increases circulating PLT counts (CTS) and PLT apheresis yields and increases platelet increments in recipients of PLT transfusions
-
Kuter D, McCullough J, Romo, J, DiPersio J, Peterson R, Armstrong S, Menchaca D, Tomita D, Goodnough LT (1997) Treatment of platelet (PLT) donors with pegylated recombinant human megakaryocyte growth and development factor (PEG-rHuMGDF) increases circulating PLT counts (CTS) and PLT apheresis yields and increases platelet increments in recipients of PLT transfusions. Blood 90 [Suppl 1]:579a
-
(1997)
Blood
, vol.90
, Issue.SUPPL. 1
-
-
Kuter, D.1
McCullough, J.2
Romo, J.3
DiPersio, J.4
Peterson, R.5
Armstrong, S.6
Menchaca, D.7
Tomita, D.8
Goodnough, L.T.9
-
23
-
-
0028199208
-
Cloning and expression of murine thrombopoietin c DNA and stimulation of platelet production in vivo
-
Lok S, Kaushansky K, Holly RD, Kuijper JL, Lofton-Day CE, Oort PJ, Grant FJ, Heipel MD, Burkhead SK, Kramer JM, Bell LA, Sprecher CA, Blumberg H, Johnson R, Prunkhard D, Ching AFT, Mathews SL, Bailey MC, Forstrom JW, Buddle MM, Osborn SG, Evans SJ, Sheppard PO, Presnell SR, ÓHara PJ, Hagen FS, Roth GJ, Foster DC (1994) Cloning and expression of murine thrombopoietin c DNA and stimulation of platelet production in vivo. Nature 369:565-568
-
(1994)
Nature
, vol.369
, pp. 565-568
-
-
Lok, S.1
Kaushansky, K.2
Holly, R.D.3
Kuijper, J.L.4
Lofton-Day, C.E.5
Oort, P.J.6
Grant, F.J.7
Heipel, M.D.8
Burkhead, S.K.9
Kramer, J.M.10
Bell, L.A.11
Sprecher, C.A.12
Blumberg, H.13
Johnson, R.14
Prunkhard, D.15
Ching, A.F.T.16
Mathews, S.L.17
Bailey, M.C.18
Forstrom, J.W.19
Buddle, M.M.20
Osborn, S.G.21
Evans, S.J.22
Sheppard, P.O.23
Presnell, S.R.24
ÓHara, P.J.25
Hagen, F.S.26
Roth, G.J.27
Foster, D.C.28
more..
-
24
-
-
0025898727
-
Recombinant human stem cell factor synergises with GM-CSF, G-CSF, IL-3 and Epo to stimulate human progenitor cells of the myeloid and erythroid lineages
-
McNiece IK, Langley KE, Zsebo KM (1991) Recombinant human stem cell factor synergises with GM-CSF, G-CSF, IL-3 and Epo to stimulate human progenitor cells of the myeloid and erythroid lineages. Exp Hematol 19:158-164
-
(1991)
Exp. Hematol.
, vol.19
, pp. 158-164
-
-
McNiece, I.K.1
Langley, K.E.2
Zsebo, K.M.3
-
25
-
-
0024996914
-
In vitro studies of erythropoietin-dependent regulation of erythropoiesis in myelodysplastic syndromes
-
Merchav S, Nielsen OJ, Rosenbaum H, Sharon R, Brenner B, Tatarsky I, Scigalla P, Wieezorek L (1990) In vitro studies of erythropoietin-dependent regulation of erythropoiesis in myelodysplastic syndromes. Leukemia 4:771-774
-
(1990)
Leukemia
, vol.4
, pp. 771-774
-
-
Merchav, S.1
Nielsen, O.J.2
Rosenbaum, H.3
Sharon, R.4
Brenner, B.5
Tatarsky, I.6
Scigalla, P.7
Wieezorek, L.8
-
26
-
-
0028775257
-
Blood. Thrombopoietin - At last
-
Metcalf D (1994) Blood. Thrombopoietin - at last. Nature 369:519-520
-
(1994)
Nature
, vol.369
, pp. 519-520
-
-
Metcalf, D.1
-
27
-
-
4243872846
-
A randomized, double-blind, placebo-controlled, dose-finding, efficacy and safety study of PEG-rHuMGDF (M) in non-Hodgkin's lymphoma(NHL) patients (pts) treated with ICE (ifosphamide, carboplatin and etoposide)
-
Moskowitz C, Nimer S, Gabrilove J et al. (1998) A randomized, double-blind, placebo-controlled, dose-finding, efficacy and safety study of PEG-rHuMGDF (M) in non-Hodgkin's lymphoma(NHL) patients (pts) treated with ICE (ifosphamide, carboplatin and etoposide). Proc Am Soc Clin Oncol 17:76a
-
(1998)
Proc. Am. Soc. Clin. Oncol.
, vol.17
-
-
Moskowitz, C.1
Nimer, S.2
Gabrilove, J.3
-
28
-
-
8544258752
-
Multilineage mobilization of peripheral blood progenitor cells in humans following administration of PEG-rHuMGDF
-
Rasko JEJ, Basser RL, Boyd J, Mansfield R, ÓMalley CJ, Hussein S, Berndt MC, Clarke K, ÓByrne J, Sheridan WP, Grigg AP, Begley CG (1997) Multilineage mobilization of peripheral blood progenitor cells in humans following administration of PEG-rHuMGDF. Br J Haematol 97:871-880
-
(1997)
Br. J. Haematol.
, vol.97
, pp. 871-880
-
-
Rasko, J.E.J.1
Basser, R.L.2
Boyd, J.3
Mansfield, R.4
ÓMalley, C.J.5
Hussein, S.6
Berndt, M.C.7
Clarke, K.8
ÓByrne, J.9
Sheridan, W.P.10
Grigg, A.P.11
Begley, C.G.12
-
29
-
-
0024539242
-
Characterization of clonogenic cells in refractory anemia with excess of blasts (RAEB-CFU): Response to recombinant hematopoietic growth factors and maturation phenotypes
-
Schouten HC, Delwel R, Bot FJ, Hagemeijer A, Touw IP, Lowenberg B (1989) Characterization of clonogenic cells in refractory anemia with excess of blasts (RAEB-CFU): response to recombinant hematopoietic growth factors and maturation phenotypes. Leuk Res 13:245-251
-
(1989)
Leuk. Res.
, vol.13
, pp. 245-251
-
-
Schouten, H.C.1
Delwel, R.2
Bot, F.J.3
Hagemeijer, A.4
Touw, I.P.5
Lowenberg, B.6
-
30
-
-
0012634387
-
FAS-triggered caspase activity is increased in sideroblastic anemia
-
Tehranchi R, Schmidt-Mende J, Forsblom L, Fadeel B, Zhivotovsky B, Heliström-Lindberg E (2001) FAS-triggered caspase activity is increased in sideroblastic anemia. Leuk Res 25 [Suppl 1]:59
-
(2001)
Leuk. Res.
, vol.25
, Issue.SUPPL. 1
, pp. 59
-
-
Tehranchi, R.1
Schmidt-Mende, J.2
Forsblom, L.3
Fadeel, B.4
Zhivotovsky, B.5
Heliström-Lindberg, E.6
-
31
-
-
0000684131
-
Recombinant human thrombopoietin (rhTPO) attenuates highdose carboplatin (C)-induced thrombocytopenia in patients with gynecologic malignancy
-
Vadhan-Raj S, Verschraegen C, McGarry L, Bueso-Ramos C, Kudelka A, Freedman R, Edwards C, Bevers M, Levenback C, Gershenson D, Jones D, Yang T, Bast RC, Kavanagh J (1997) Recombinant human thrombopoietin (rhTPO) attenuates highdose carboplatin (C)-induced thrombocytopenia in patients with gynecologic malignancy. Blood 90 [Suppl 1]:580a
-
(1997)
Blood
, vol.90
, Issue.SUPPL. 1
-
-
Vadhan-Raj, S.1
Verschraegen, C.2
McGarry, L.3
Bueso-Ramos, C.4
Kudelka, A.5
Freedman, R.6
Edwards, C.7
Bevers, M.8
Levenback, C.9
Gershenson, D.10
Jones, D.11
Yang, T.12
Bast, R.C.13
Kavanagh, J.14
-
32
-
-
0029024169
-
The effect of stem-cell factor, interleukin-3 and erythropoietin on in vitro erythropoiesis in myelodysplastic syndromes
-
Verbeek W, Vehmeyer K, Wörmann B, Hiddemann W (1995) The effect of stem-cell factor, interleukin-3 and erythropoietin on in vitro erythropoiesis in myelodysplastic syndromes. J Cancer Res Clin Oncol 121:338-342
-
(1995)
J. Cancer Res. Clin. Oncol.
, vol.121
, pp. 338-342
-
-
Verbeek, W.1
Vehmeyer, K.2
Wörmann, B.3
Hiddemann, W.4
-
33
-
-
0026654942
-
Effect of in vitro growth of haematopoietic progenitors in patients with myelodysplastic syndromes
-
Visani G, Tosi P, Finelli C, Gamberi B, Zauli G, Cenacchi A, Fogli M, Colombini R, Tura S (1992) Effect of in vitro growth of haematopoietic progenitors in patients with myelodysplastic syndromes. Haematologica 77:142-145
-
(1992)
Haematologica
, vol.77
, pp. 142-145
-
-
Visani, G.1
Tosi, P.2
Finelli, C.3
Gamberi, B.4
Zauli, G.5
Cenacchi, A.6
Fogli, M.7
Colombini, R.8
Tura, S.9
-
34
-
-
0028176283
-
c-Mpl ligand is a humoral regulator of megakaryopoiesis
-
Wendling F, Maraskovsky E, Debili N, Florindo C, Teepe M, Titeux M, Methia N, Breton-Gorius J, Cosman D, Vainchenker W (1994) c-Mpl ligand is a humoral regulator of megakaryopoiesis. Nature 369:571-574
-
(1994)
Nature
, vol.369
, pp. 571-574
-
-
Wendling, F.1
Maraskovsky, E.2
Debili, N.3
Florindo, C.4
Teepe, M.5
Titeux, M.6
Methia, N.7
Breton-Gorius, J.8
Cosman, D.9
Vainchenker, W.10
-
35
-
-
17744390344
-
Recombinant human thrombopoietin after autologeous bone marrow transplantation: A phase I pharmacokinetic and pharmacodynamic study
-
Wolff SN, Herzig R, Lynch J, Ericson SG, Greer JP, Stein R, Goodman S, Benyunes MC, Ashby M, Jones DV, Fay J (2001) Recombinant human thrombopoietin after autologeous bone marrow transplantation: a phase I pharmacokinetic and pharmacodynamic study. Bone Marrow Transplant 27:261-268
-
(2001)
Bone Marrow Transplant
, vol.27
, pp. 261-268
-
-
Wolff, S.N.1
Herzig, R.2
Lynch, J.3
Ericson, S.G.4
Greer, J.P.5
Stein, R.6
Goodman, S.7
Benyunes, M.C.8
Ashby, M.9
Jones, D.V.10
Fay, J.11
-
36
-
-
0025764755
-
A phase I/II trial of recombinant human granulocyte colony-stimulating factor in the myelodysplastic syndromes
-
Yoshida Y, Hirashima K, Asano S, Takaku F (1991) A phase I/II trial of recombinant human granulocyte colony-stimulating factor in the myelodysplastic syndromes. Br J Haematol 78:378-384
-
(1991)
Br. J. Haematol.
, vol.78
, pp. 378-384
-
-
Yoshida, Y.1
Hirashima, K.2
Asano, S.3
Takaku, F.4
|