Plasma homocysteine concentration changes after renal transplantation in children

Pediatric Nephrology

Volumn 17, Issue 7, 2002, Pages 520-523

  Merouani, Aicha ^a   Delvin, Edgar E ^a   Genest Jr , Jacques ^b   Rozen, Rima ^c   Lambert, Marie ^a  

^a UNIVERSITY OF MONTREAL   (Canada)

^b ROYAL VICTORIA HOSPITAL   (Canada)

^c MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

Author keywords

Chronic renal failure; Folic acid; Plasma homocysteine; Renal transplantation; Vitamin B12

Indexed keywords

ALBUMIN; AZATHIOPRINE; CYANOCOBALAMIN; CYCLOSPORIN A; FOLIC ACID DERIVATIVE; HOMOCYSTEINE; IMMUNOSUPPRESSIVE AGENT; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISONE; TACROLIMUS;

ADOLESCENT; ALBUMIN BLOOD LEVEL; AMINO ACID BLOOD LEVEL; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FOLIC ACID BLOOD LEVEL; GLOMERULUS FILTRATION RATE; HEMODIALYSIS; HUMAN; HYPERHOMOCYSTEINEMIA; KIDNEY FAILURE; KIDNEY FUNCTION; KIDNEY TRANSPLANTATION; MALE; PRESCHOOL CHILD; PRIORITY JOURNAL; RENAL SYSTEM PARAMETERS; RISK FACTOR; SCHOOL CHILD; SCORING SYSTEM; STANDARD; VASCULAR DISEASE; VITAMIN SUPPLEMENTATION;

EID: 0036952052     PISSN: 0931041X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00467-002-0868-4     Document Type: Article

References (19)

1. Selhub J, Jacques PF, Bostom AG, D'Agostino RB, Wilson W, Belinger AJ, O'Leary DH, Wolf PA, Schaefer EJ, Rosenberg IH (1995) Association between plasma homocysteine concentration and extracranial carotid artery stenosis. N Engl J Med 332:286-291
2. Robinson K, Gutpa A, Dennis V, Arheart K, Chaudhary D, Green R, Vigo P, Mayer EL, Selhub J, Kutner M, Jacobsen DW (1996) Hyperhomocysteinemia confers an independent increased risk factor of atherosclerosis in end-stage renal disease and is closely related to plasma folate and pyridoxine concentrations. Circulation 94:2743-2748
3. Bostom AG, Lathrop L (1997) Hyperhomocysteinemia in end-stage renal disease: prevalence, etiology, and potential relationship to arteriosclerotic outcomes. Kidney Int 52:10-20
4. Lilien M, Duran M, Hoeck K van, Tien Poll-The BT, Schroder C (1999) Hyperhomocysteinemia in children with chronic renal failure. Nephrol Dial Transplant 14:366-368
5. Merouani A, Lambert M, Delvin EE, Genest Jr J, Robitaille P, Rozen R (2001) Plasma homocysteine concentration in children with chronic renal failure. Pediatr Nephrol 16:805-811
6. Arnadottir M, Hultberg B, Nilsson-Ehle P, Thysell H (1996) The effect of reduced glomerular filtration rate on plasma total homocysteine concentration. Scand J Clin Lab Invest 56:41-46
7. Arnadottir M, Hultberg B, Wahlberg J, Fellstrom B, Dimeny E (1998) Serum total homocysteine concentration before and after renal transplantation. Kidney Int 54:1380-1384
8. Merouani A, Rozen R, Clermont MJ, Genest Jr J (2002) Renal function, homocysteine and other plasma thiol concentrations during the post renal transplant period. Transplant Proc (in press)
9. 12 and folate status on plasma homocysteine concentration in children. Am J Clin Nutr 72:1469-1473
10. Lussier-Cacan S, Xhignesse M, Piolot A, Selhub J, Davignon J, Genest J Jr (1996) Plasma homocysteine in healthy subjects: sex-specific relation with biological traits. Am J Clin Nutr 64:587-593
11. Schwartz GJ, Haycock GB, Edelmann CM Jr, Spitzer A (1976) A simple estimate of glomerular filtration rate in children derived from body length and plasma creatinine. Pediatrics 58:259-263
12. Jacques PF, Bostom AG, William RR, Ellison RC, Eckfeldt JH, Rosenberg IH, Selhub J, Rozen R (1996). Relation between folate status, a common mutation in the methylenetetrahydrofolate reductase and plasma homocysteine concentration. Circulation 93:7-9
13. Bostom AG, Shemin D, Lapane KL, Nadeau MR, Sutherland P, Chan J, Rozen R, Yoburn D, Jacques PF, Selhub J, Rosenberg IH (1996) Folate status is the major determinant of fasting total plasma homocysteine levels in maintenance dialysis patients. Atherosclerosis 123:193-202
14. Wilken DEL, Gutpa VJ, Betts AK, (1981) Homocysteine in the plasma of renal transplant recipients: effects of cofactors for methionine metabolism. Clin Sci (Colch) 61:743-749
15. Bostom AG, Gohh RY, Beaulieu AJ, Han H, Jacques PF Selhub J, Dworkin L, Rosenberg IH (1999) Determinants of fasting plasma total homocysteine levels among chronic stable renal transplantation. Transplantation 68:257-261
16. Arnadottir M, Hultberg B, Vladov V, Nilsson-Ehle P, Thysell H (1996) Hyperhomocysteinemia in cyclosporine-treated renal transplant recipients. Transplantation 61:509-512
17. Woodside JV, Fogarty DG, Lightbody JH, Loughrey CM, Yarnell JWG, Maxwell AP, Young IS (1999) Homocysteine and B-group vitamins in renal transplant patients. Clin Chim Acta 282:157-166
18. 6 concentrations. Prevalent risk factors for vascular disease in heart transplant recipients. Transplantation 65:544-550
19. Bostom AG, Shemin D, Gohh RY, Beaulieu AJ, Jacques PF, Dworkin L, Selhub J (2000) Treatment of mild hyperhomocysteinemia in renal transplant recipients versus hemodialysis patients. Transplantation 69:2128-2131