Determinants of fasting plasma total homocysteine levels among chronic stable renal transplant recipients

Transplantation

Volumn 68, Issue 2, 1999, Pages 257-261

  Bostom, Andrew G ^a,b,c   Gohh, Reginald Y ^b   Beaulieu, Andrew J ^b   Han, Haewook ^a   Jacques, Paul F ^a   Selhub, Jacob ^a   Dworkin, Lance ^b   Rosenberg, Irwin H ^a  

^a MEMORIAL HOSPITAL OF RHODE ISLAND   (United States)

^b RHODE ISLAND HOSPITAL   (United States)

^c TUFTS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYANOCOBALAMIN; FOLIC ACID; HOMOCYSTEINE; PYRIDOXAL 5 PHOSPHATE;

ADULT; AGED; AMINO ACID BLOOD LEVEL; ARTICLE; CARDIOVASCULAR RISK; DIET RESTRICTION; FEMALE; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; KIDNEY FUNCTION; KIDNEY GRAFT; MALE; PRIORITY JOURNAL; RECIPIENT; VITAMIN INTAKE;

ADULT; AGED; CREATININE; FASTING; FEMALE; FOLIC ACID; HOMOCYSTEINE; HUMANS; KIDNEY TRANSPLANTATION; MALE; MIDDLE AGED;

EID: 0033609464     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-199907270-00017     Document Type: Article

References (22)

1. Massy ZA, Chadefaux-Vekemans B, Chevalier A, Bader CA, Drueke TB, Legendre C, et al. Hyperhomocystinemia: a significant risk factor for cardiovascular disease in renal transplant recipients. Nephrol Dial Transplant 1994; 9: 1103.
2. Selhub J, Jacques PF, Wilson PWF, Rush D, Rosenberg IH. Vitamin status and intake as primary determinants of homocystinemia in an elderly population. JAMA 1993; 270: 2693.
3. Arnadottir M, Hultberg B, Vladov V, Nilsson-Ehle P, Thysell H. Hyperhomocystinemia in cyclosporine-treated renal transplant recipients. Transplantation 1996; 61: 509.
4. Bostom AG, Gohh RY, Tsai MY, et al. Excess prevalence of fasting and post-methionine loading hyperhomocystinemia in stable renal transplant recipients. Arterioscler Thromb Vasc Biol 1997; 17: 1894.
5. Ducloux D, Fournier V, Rebibou JM, Bresson-Vautrin C, Gibey R, Chalopin JM. Hyperhomocystinemia in renal transplant recipients with and without cyclosporine. Clin Nephrol 1998; 19: 232.
6. Ducloux D, Ruedin C, Gibey R, et al. Prevalence, determinants, and clinical significance of hyperhomocystinemia in renal transplant recipients. Nephrol Dial Transplant 1998; 13: 2890.
7. Ueland P, Refsum H, Stabler SP, Malinow MR, Andersson A, Allen RH. Total homocysteine in plasma or serum: methods and applications. Clin Chem 1993; 39: 1764.
8. Folic acid content of some grain foods is mandated by FDA. The Wall Street Journal, Monday, January 5, 1998.
9. Food standards: amendment of standards of identity for enriched grain products to require addition of folic acid. Federal Register. March 5, 1996; 61: 8781.
10. Tucker KL, Mahnken B, Wilson PWF, Jacques PF, Selhub J. Folic acid fortification of the food supply: potential benefits and risks to the elderly population. JAMA 1996; 276: 1879.
11. 12, pantothenic acid, biotin, and choline. A report of the standing committee on the scientific evaluation of dietary reference intakes and its panel on folate, other B-vitamins and choline, and subcommittee on upper reference levels of nutrients. Washington, DC: National Academy Press, 1998.
12. Smulders YM, de Man AME, Stehouwer CDA, Slaats EH. Trimethoprim and fasting plasma homocysteine. Lancet 1998; 352: 1827.
13. Cockcroft DW, Gault MH. Prediction of creatinine clearance from serum creatinine. Nephron 1976; 16: 31.
14. Bostom AG, Shemin D, Lapane KL, Hume AL, Yoburn D, Nadeau MR, et al. High-dose B-vitamin treatment of hyperhomocystinemia in dialysis patients. Kidney Int 1996; 49: 147.
15. Chauveau P, Chadefaux B, Coude M, Aupetit J, Kamoun P, Jungers P. Long-term folic acid (but not pyridoxine) supplementation lowers elevated plasma homocysteine level in chronic renal failure. Miner Electrolyte Metab 1996; 22: 106.
16. Malinow MR, Nieto FJ, Kruger WD, Duell PB, Hess DL, Gluckman RA, et al. The effects of folic acid supplementation on plasma total homocysteine are modulated by multivitamin use and methylenetetrahydrofolate reductase genotypes. Arterioscler Thromb Vasc Biol 1997; 17: 1157.
17. Lowering blood homocysteine with folic acid based supplements: meta-analysis of randomized trials. Homocysteine Lowering Trialists' Collaboration. BMJ 1998; 316: 894.
18. Bostom AG, Lathrop L. Hyperhomocystinemia in end-stage renal disease: prevalence, etiology, and potential relationship to arteriosclerotic outcomes. Kidney Int 1997; 52: 10.
19. Bostom AG, Brosnan JT, Hall B, Nadeau MR, Selhub J. Net uptake of plasma homocysteine by the rat kidney in vivo. Atherosclerosis 1995; 116: 59.
20. van Guldener C, Donker AJ, Jakobs C, Teerlink T, de Meer K. No net renal extraction of homocysteine in fasting humans. Kidney Int 1998; 54: 166.
21. Arnadottir M, Hultberg B, Wahlberg J, Fellstrom B, Dimeny E. Serum total homocysteine concentration before and after renal transplantation. Kidney Int 1998; 54: 1380.
22. Bostom AG, Gohh RY, Beaulieu AJ, Nadeau MR, Hume AL, Jacques PF, et al. Treatment of hyperhomocystinemia in renal transplant recipients: a randomized, placebo-controlled trial. Ann Intern Med 1997; 127: 1089.