Neuronal degeneration and glial cell-responses following trimethyltin intoxication in the rat

Acta Neuropathologica

Volumn 103, Issue 6, 2002, Pages 575-582

  Haga, S ^a   Haga, C ^a   Aizawa, T ^a   Ikeda, K ^a  

^a TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

Author keywords

Astrocytes; Gallyas Braak impregnation method; Microglia; Neurodegeneration; Trimethyltin

Indexed keywords

GLIAL FIBRILLARY ACIDIC PROTEIN; MONOCLONAL ANTIBODY; RABBIT ANTISERUM; TRIMETHYLTIN;

ANALYTIC METHOD; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARGYROPHILIA; ARTICLE; ASTROCYTE; BRAIN INJURY; CELL ACTIVATION; CELL REGENERATION; CELL STRUCTURE; CONTROLLED STUDY; DENTATE GYRUS; DOSE RESPONSE; GLIA CELL; GRANULE CELL; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; MACROGLIA; MALE; MICROGLIA; NERVE CELL DEGENERATION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PYRIFORM CORTEX; RAT; SENSITIVITY AND SPECIFICITY; TIME;

ANIMALS; ASTROCYTES; BODY WEIGHT; CALCIUM-BINDING PROTEINS; GLIAL FIBRILLARY ACIDIC PROTEIN; GLIOSIS; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; MALE; MICROGLIA; NERVE DEGENERATION; NERVE REGENERATION; NERVE TISSUE PROTEINS; NEURONS; RATS; RATS, SPRAGUE-DAWLEY; TRIMETHYLTIN COMPOUNDS;

EID: 0036943718     PISSN: 00016322     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00401-001-0505-5     Document Type: Article

References (38)

1. Akiyama H, Tooyama I, Kondo H, Ikeda K, Kimura H, McGeer EG, McGeer PL (1994) Early response of brain resident microglia to kainic acid-induced hippocampal lesions. Brain Res 635:257-268
2. Aschner M, Gannon M, Kimelberg HK (1992) Interactions of trimethyl tin (TMT) with rat primary astrocyte cultures: altered uptake and efflux of rubidium, L-glutamate and D-aspartate. Brain Res 582:181-185
3. Balaban CD, O'Callaghan JP, Billingsley ML (1988) Trimethyltin-induced neuronal damage in the rat brain: comparative studies using silver degeneration stains, immunocytochemistry and immunoassay for neuronotypic and gliotypic proteins. Neuroscience 26:337-361
4. Bechmann I, Nitsch R (1997) Astrocytes and microglial cells incorporate degenerating fibers following entorhinal lesion: a light, confocal, and electron microscopical study using a phagocytosis-dependent labeling technique. Glia 20:145-154
5. Bouldin TW, Goines ND, Bagnell CR, Krigman MR (1981) Pathogenesis of trimethyltin neuronal toxicity: ultrastructural and cytochemical observations. Am J Pathol 104:237-249
6. Braak H, Braak E, Ohm T, Bohl J (1988) Silver impregnation of Alzheimer's neurofibrillary changes counterstained for basophilic material and lipofuscin pigment. Stain Technol 63: 197-200
7. Brown AW, Aldridge WN, Street BW, Verschoyle RD (1979) The behavioral and neuropathologic sequelae of intoxication by trimethyltin compounds in the rat. Am J Pathol 97:59-82
8. Bruccoleri A, Brown H, Harry GJ (1998) Cellular localization and temporal elevation of tumor necrosis factor-α, interleukin-1α, and transforming growth factor-β1 mRNA in hippocampal injury response induced by trimethyltin. J Neurochem 71:1577-1587
9. Bruccoleri A, Pennypacker KR, Harry GJ (1999) Effect of dexamethasone on elevated cytokine mRNA levels in chemical-induced hippocampal injury. J Neurosci Res 57:916-926
10. Chang LW, Dyer RS (1983) A time-course study of trimethyltin induced neuropathology in rats. Neurobehav Toxicol Teratol 5:443-459
11. Chang LW, Dyer RS (1985) Septotemporal gradients of trimethyltin-induced hippocampal lesions. Neurobehav Toxicol Teratol 7:43-49
12. Chang LW, Wenger GR, McMillan DE, Dyer RS (1983) Species and strain comparison of acute neurotoxic effects of trimethyltin in mice and rats. Neurobehav Toxicol Teratol 5: 337-350
13. Dyer RS, Walsh TJ, Wonderlin WF, Bercegeay M (1982) The trimethyltin syndrome in rats. Neurobehav Toxicol Teratol 4: 127-133
14. Gallyas F, Zoltay G, Dames W (1992) Formation of "dark" (argyrophilic) neurons of various origin proceeds with a common mechanism of biophysical nature (a novel hypothesis). Acta Neuropathol 83:504-509
15. Gehrmann J, Bonnekoh P, Miyazawa T, Oschlies U, Dux E, Hossmann K-A, Kreutzberg GW (1992) The microglial reaction in the rat hippocampus following global ischemia: immuno-electron microscopy. Acta Neuropathol 84:588-595
16. Gehrmann J, Banati RB, Wiessner C, Hossmann K-A, Kreutzberg GW (1995) Review: reactive microglia in cerebral ischaemia: an early mediator of tissue damage? Neuropathol App Neurobiol 21:277-289
17. Haga S, Akai K, Ishii T (1989) Demonstration of microglial cells in and around senile (neuritic) plaques in the Alzheimer brain: an immunohistochemical study using a novel monoclonal antibody. Acta Neuropathol 77:569-575
18. Hailer NP, Grampp A, Nitsch R (1999) Proliferation of microglia and astrocytes in the dentate gyrus following entorhinal cortex lesion: a quantitative bromodeoxyuridine-labelling study. Eur J Neurosci 11:3359-3364
19. Hsu S-M, Soban E (1982) Color modification of diaminobenzidine (DAB) precipitation by metallic ions and its application for double immunohistochemistry. J Histochem Cytochem 30: 1079-1082
20. Ishida N, Akaike M, Tsutsumi S, Kanai H, Masui A, Sadamatsu M, Kuroda Y, Watanabe Y, McEwen BS, Kato N (1997) Trimethyltin syndrome as a hippocampal degeneration model: temporal changes and neurochemical features of seizure susceptibility and learning impairment. Neuroscience 81:1183-1191
21. Jørgensen MB, Finsen BR, Jensen MB, Castellano B, Diemer NH, Zimmer J (1993) Microglial and astroglial reactions to ischemic and kainic acid-induced lesions of the adult rat hippocampus. Exp Neurol 120:70-88
22. Kimelberg HK, Norenberg MD (1989) Astrocytes. Sci Am 260:44-52
23. Koczyk D, Oderfeld-Nowak B (2000) Long-term microglial and astroglial activation in the hippocampus of trimethyltin-intoxicated rat: stimulation of NGF and TrkA immunoreactivities in astroglia but not in microglia. Int J Dev Neurosci 18:591-606
24. Kutscher CL (1992) A morphometric analysis of trimethyltin-induced change in rat brain using the Timm technique. Brain Res Bull 28:519-527
25. Maier WE, Brown HW, Tilson HA, Luster MI, Harry GJ (1995) Trimethyltin increases interleukin (IL)-1* IL-6 and tumor necrosis factor α mRNA levels in rat hippocampus. J Neuroimmunol 59:65-75
26. McCann MJ, O'Callaghan JP, Martin PM, Bertram T, Streit WJ (1996) Differential activation of microglia and astrocytes following trimethyl tin-induced neurodegeneration. Neuroscience 72:273-281
27. McGeer PL, Itagaki S, McGeer EG (1988) Expression of the histocompatibility glycoprotein HLA-DR in neurological disease. Acta Neuropathol 76:550-557
28. McTigue DM, Popovich PG, Morgan TE, Stokes BT (2000) Localization of transforming growth factor-β1 and receptor mRNA after experimental spinal cord injury. Exp Neurol 163: 220-230
29. Monnet-Tschudi F, Zurich M-G, Pithon E, Melle G van, Honegger P (1995) Microglial responsiveness as a sensitive marker for trimethyltin (TMT) neurotoxicity. Brain Res 690:8-14
30. Nolan CC, Brown AW, Cavanagh JB (1990) Regional variations in nerve cell responses to trimethyltin intoxication in Mongolian gerbils and rats; further evidence for involvement of the Golgi apparatus. Acta Neuropathol 81:204-212
31. Patanow CM, Day JR, Billingsley ML (1997) Alterations in hippocampal expression of SNAP-25, GAP-43, stannin and glial fibrillary acidic protein following mechanical and trimethyltin-induced injury in the rat. Neuroscience 76:187-202
32. Patel M, Ardelt BK, Yim GK, Isom GE (1990) Interaction of trimethyltin with hippocampal glutamate. Neurotoxicology 11: 601-608
33. Sloviter RS, von Knebel Doeberitz C, Walsh TJ, Dempster DW (1986) On the role of seizure activity in the hippocampal damage produced by trimethyltin. Brain Res 367:169-182
34. Streit WJ, Hurley SD, McGraw TS, Semple-Rowland SL (2000) Comparative evaluation of cytokine profiles and reactive gliosis supports a critical role for interleukin-6 in neuronglia signaling during regeneration. J Neurosci Res 61:10-20
35. Swartzwelder HS, Holahan W, Myers RD (1983) Antagonism by D-amphetamine of trimethyltin-induced hyperactivity: evidence toward an animal model of hyperkinetic behavior. Neuropharmacology 22:1049-1054
36. Tanaka S, Suzuki K, Watanabe M, Matsuda A, Tone S, Koike T (1998) Upregulation of a new microglial gene, mrf-1, in response to programmed neuronal cell death and degeneration. J Neurosci 18:6358-6369
37. Thompson TA, Lewis JM, Dejneka NS, Severs WB, Polavarapu R, Billingsley ML (1996) Induction of apoptosis by organotin compounds in vitro: neuronal protection with antisense oligonucleotides directed against stannin. J Pharmacol Exp Ther 276:1201-1215
38. Toggas SM, Krady JK, Billingsley ML (1992) Molecular neurotoxicology of trimethyltin: identification of stannin, a novel protein expressed in trimethyltin-sensitive cells. Mol Pharmacol 42:44-56