Comparative biotransformation of morphine, codeine and pholcodine in rat hepatocytes: Identification of a novel metabolite of pholcodine

Xenobiotica

Volumn 32, Issue 12, 2002, Pages 1093-1107

  Jairaj, M ^a   Watson, D G ^a   Grant, M H ^b   Gray, A I ^a   Skellern, G G ^c  

^a UNIVERSITY OF STRATHCLYDE   (United Kingdom)

^b Bioengineering Unit   (United Kingdom)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

CODEINE; DRUG METABOLITE; MORPHINE; PHOLCODINE;

ANIMAL CELL; ARTICLE; BIOTRANSFORMATION; COMPARATIVE STUDY; DEALKYLATION; DEMETHYLATION; DRUG TRANSFORMATION; LIVER CELL; LIVER MICROSOME; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OXIDATION; PHASE SEPARATION; RAT;

ANALGESICS, OPIOID; ANIMALS; ANTITUSSIVE AGENTS; CHROMATOGRAPHY, LIQUID; CODEINE; GLUCURONIDASE; HEPATOCYTES; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MASS SPECTROMETRY; MODELS, CHEMICAL; MORPHINE; MORPHOLINES; OXYGEN; RATS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TIME FACTORS;

ANIMALIA;

EID: 0036917659     PISSN: 00498254     EISSN: None     Source Type: Journal    
DOI: 10.1080/0049825021000017911     Document Type: Article

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