Skin antibiotics get in the loop

Nature Medicine

Volumn 8, Issue 12, 2002, Pages 1359-1360

  Kopp, Elizabeth ^a   Medzhitov, Ruslan ^a,b  

^a YALE UNIVERSITY   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; B7 ANTIGEN; BETA DEFENSIN; CD86 ANTIGEN; DEFENSIN; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; PEPTIDE; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA;

BINDING AFFINITY; DENDRITIC CELL; ESCHERICHIA COLI; IMMUNE RESPONSE; IMMUNE SYSTEM; MUCOSAL IMMUNITY; NONHUMAN; PRIORITY JOURNAL; SHORT SURVEY; T LYMPHOCYTE;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; BETA-DEFENSINS; DENDRITIC CELLS; DROSOPHILA PROTEINS; HUMANS; LIPOPOLYSACCHARIDES; MEMBRANE GLYCOPROTEINS; RECEPTORS, CELL SURFACE; TOLL-LIKE RECEPTORS;

ESCHERICHIA COLI;

EID: 0036917456     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/nm1202-1359     Document Type: Short Survey

References (6)

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3. Ulevitch, R.I. & Tobias, P.S. Receptor-dependent mechanisms of cell stimulation by bacterial endotoxin. Annu. Rev. Immunol. 13, 437-457 (1995).
4. Raj, P.A. & Dentino, A.R. Current status of defensins and their role in innate and adaptive immunity. FEMS Microbiol. Lett. 206, 9-18 (2002).
5. Lehrer, R.I. & Ganz, T. Defensins of vertebrate animals. Curr. Opin. Immunol. 14, 96-102 (2002).
6. Biragyn, A. et al. Mediators of innate immunity that target immature, but not mature, dendritic cells induce antitumor immunity when genetically fused with nonimmunogenic tumor antigens. J. Immunol. 167, 6644-6653 (2001).