Atherosclerosis: Cell biology and lipoproteins: Cholesterol absorption inhibitors: Gateway therapy for hypercholesterolaemia

Current Opinion in Lipidology

Volumn 13, Issue 6, 2002, Pages 701-703

  Brown, Andrew J ^a  

^a UNIVERSITY OF NEW SOUTH WALES   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ATORVASTATIN; CHOLESTEROL; EZETIMIBE; LIPOPROTEIN; SIMVASTATIN;

ATHEROSCLEROSIS; CHO CELL; CHOLESTEROL METABOLISM; CHOLESTEROL TRANSPORT; CLINICAL TRIAL; CYTOLOGY; DRUG MECHANISM; HUMAN; HYPERCHOLESTEROLEMIA; KNOCKOUT MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; SHORT SURVEY; SIDE EFFECT;

ANIMALS; ANTICHOLESTEREMIC AGENTS; ARTERIOSCLEROSIS; AZETIDINES; CHOLESTEROL; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; HYPERCHOLESTEROLEMIA; INTESTINAL ABSORPTION; LIPOPROTEINS;

EID: 0036913945     PISSN: 09579672     EISSN: None     Source Type: Journal    
DOI: 10.1097/00041433-200212000-00016     Document Type: Short Survey

References (8)

1. Miettinen TA, Gylling H. Regulation of cholesterol metabolism by dietary plant sterols. Curr Opin Lipidol 1999; 10:9-14.
2. Bays HE, Moore PB, Drehobl MA, et al., for the Ezetimibe Study Group. Effectiveness and tolerability of ezetimibe in patients with primary hypercholesterolemia: Pooled analysis of two-phase II studies. Clin Therapeut 2001; 23:1209-1230.
3. Meng CQ. Ezetimibe. Schering-Plough. Curr Opin Invest Drugs 2002; 3:427-432.
4. Gagne C, Gaudet D, Bruckert E, for the Ezetimibe Study Group. Efficacy and safety of ezetimibe coadministered with atorvastatin or simvastatin in patients with homozygous familial hypercholesterolemia. Circulation 2002; 105:2469-2475.
5. Van Heek M, Farley C, Compton DS, et al. Ezetimibe selectively inhibits intestinal cholesterol absorption in rodents in the presence and absence of exocrine pancreatic function. Br J Pharmacol 2001; 134:409-417.
6. Altmann SW, Davis Jr HR, Yao X, et al. The identification of the intestinal scavenger receptor class B, type I (SR-BI) by expression cloning and its role in cholesterol absorption. Biochim Biophys Acta 2002; 1580:77-93.
7. Mardones P, Quinones V, Amigo M, et al. Hepatic cholesterol and bile acid metabolism and intestinal cholesterol absorption in scavenger receptor class B type 1-deficient mice. J Lipid Res 2001; 42:170-180.
8. Kramer W, Glombik H, Petry S, et al. Identification of binding proteins for cholesterol absorption inhibitors as components of the intestinal cholesterol transporter. FEBS Lett 2000; 487:293-297.