Humoral immune response of rats vaccinated with cDNA or protein form of glutathione-S-transferase of Fasciola hepatica to infection with metacercariae of the fluke

Helminthologia

Volumn 39, Issue 3, 2002, Pages 127-133

  Wedrychowicz H ^a,c   Szymanski P ^b   Panasiuk, L Jedlina ^a   Bienkowska Szewczyk, K ^b  

^a W STEFA SKI INSTITUTE OF PARASITOLOGY   (Poland)

^b UNIVERSITY OF GDA SK   (Poland)

^c WARSAW UNIVERSITY OF LIFE SCIENCES   (Poland)

Author keywords

DNA vaccination; Fasciola hepatica; Glutathione S transferase

Indexed keywords

ANIMALIA; FASCIOLA; FASCIOLA HEPATICA; HEPATICA; PARALICHTHYS DENTATUS; TREMATODA;

EID: 0036910871     PISSN: 04406605     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (44)

1. Anon, (1995): Control of Foodborne Trematode Infections. WHO Technical Series No 849,WHO, Geneva
2. Armour, J., Dargie, J. D. (1974): Immunity to Fasciola hepatica in the rat: Successful transfer of immunity by lymphoid cells and by serum. Exp Parasitol., 35: 381-388
3. Behm, C. A., Sangster, N. C. (1998): Pathology, Pathophysiology and Clinical Aspects. In. (Ed.) Dalton, J. P. Fasciolosis, CABI Publishing
4. Bjorland, J., Bryan, T. T., Strauss, W., Hillyer, G. V., Mcauley, J. B. (1995): An outbreak of acute fascioliasis among Aymara indians in Bolivian Altiplano. Clin Infect. Dis., 21: 1228-1223
5. Brophy, P. M., Barrett, J. (1990): Strategies for detoxification of aldehyde products of lipidperoxidation in helminths. Mol. Biochem. Parasitol., 42: 205-211
6. Brophy, P. M., Pritehard, D. I. (1994): Parasitic helminth glutathione S-transferases an update on their potential as targets for immuno- and chemotherapy. Ex.p Parasitol., 79: 89-96
7. Cervi, L., Rossi, G., Masih, D. T. (1999): Potential role for excretory-secretory forms of glutathione-S-transferase (GST) in Fasciola hepatica. Parasitology, 119: 627-633
8. Doy, T. G., Hughes, D. L., Harness, E. (1978): Resistance of rats to reinfection with Fasciola hepatica and possible involvement of intestinal eosinophil leucocytes. Res. Vet. Sci., 25: 41-44
9. Doy, T. G., Hughes, D. L. (1982): Evidence for two distinct mechanisms of resistance in the rat to reinfection with Fasciola hepatica. Int. J. Parasitol., 4: 357-361
10. Esteban, J. G., Flores, A., Aguirre, C., Strauss, W., Angles, R., Mas Coma, S. (1997): Presence of very high prevalence and intensity of infection with Fasciola hepatica among Aymara children from the Northen Bolivian Altiplano. Acta Trop., 66: 1-14
11. Harn, D. A., Reynolds, S. R., Chikunguwo, S., Dissayanake, S., Skelly, P., Shoemaker, C., Okano, M. (1998): Peptide and DNA vaccines for schistosomiasis, and discovery of a novel adjuvant that promotes antibody responses. Parasitol. Int. 47 suppl. 14
12. Harness, E., Doy, T. G., Hughes, D. L. (1977) The early migratory behaviour of young Fasciola hepatica in sensitized mice. Int. J. Parasitol., 7: 51-57
13. Hillyer, G. V. (1998): Immunodignosis of Human and Animal Fasciolosis. In. (Ed.) Dalton J. P. Fasciolosis; CABI Publishing
14. Howell, M. J., Board, P. G., Boray, J. C. (1988): Glutathione S-transferases in Fasciola hepatica. J. Parasitol., 74: 715-718
15. Keegan, P. S., Trudgett, A. (1992): Fasciola hepatica in the rat: immune responses associated with the development of resistance to infection. Parasit Immunol., 14: 657-669
16. Kofta, W., Mieszczanek, J., Płucienniczak, G., Wȩdrychowicz, H. (2000): Successful DNA immunisation of rats against fasciolosis. Vaccine, 18: 1985-2990
17. Kofta, W., Wedrychowicz, H. (2001): Anti-parasite DNA vaccines: advantages and disadvantages. Vet. Parasitol., 100: 3-12
18. Lawrence, R. A., Denham, D. A. (1993): Stage and isotype specific immune responses in a rat model of filariasis. Parasit. Immunol., 15: 429-439
19. Mas-Coma, S., Bargues, M. D., Esteban, E. G. (1998): Human Fasciolosis. In Dalton J. P. (Ed.): Fasciolosis. CABI Publishing
20. Meddis, R. (1984): Statistics Using Ranks. A Unified Approach. Basil Blackwell Publishers Ltd., New York
21. Meeusen, E. N. T. (1999): Immunology of helminth infections, with special reference to immunopathology. Vet. Parasitol., 84: 259-273
22. Meeusen, E. N. T., Brandon, M. R. (1994): The use of antibody-secreting cell probes to reveal tissue-restricted immune responses during infection. Eur. J. Immunol., 24: 469-474
23. Milbourne, E. A., Howell, M. J. (1990): Eosinophil responses to Fasciola hepatica in rodents. Int. J. Parasitol., 20: 705-708
24. Milbourne, E. A., Howell, M. J. (1997): Eosinophilia in nude rats and nude mice after infection with Fasciola hepatica or injection with its E/S antigens. Int. J. Parasitol., 27: 1099-1105
25. Morrison, C. A., Colin, T., Sexton, J. L., Bowem, F., Wicker, J., Friedel, T., Spithill, T. W. (1996): Protection of cattle against Fasciola hepatica infection by vaccination with glutathione S-transferase. Vaccine, 14: 1603-1612
26. Mosman, T. R., Coffman, R. L. (1989): Th1 and Th2 cells: Different patterns of lymphokine secretion lead to different functional properties. Ann. Rev. Immunol., 7: 145-173
27. Mulcahy, G., O'Connor, F., Clery, D., Hogan, S. F., Dowd, A. J., Andrews, S. J., Dalton J. P. (1999): Immune responses of cattle to experimental anti - Fasciola hepatica vaccines. Res. Vet. Sci., 67: 27-33
28. O'Neill, S. M., Brady, M. T., Callanan, J. J., Mulcahy, G., Joyce, P., Mills, K. H. G., Dalton, J. P. (2000): Fasciola hepatica infection downregulates Th1 responses in mice. Parasit. Immunol., 22: 147-155
29. Panaccio, M., Wilson, L. R., Crameri, S. L., Wijffels, G. L., Spithill, T. W. (1992): Molecular chracterisation of cDNA sequences encoding glutathione S-transferases of Fasciola hepatica. Exp. Parasitol., 74: 232-237
30. Paz, A., Sanchez-Andrade, R., Panadero, R., Diez-Banos P., Morrondo P. (1998): IgG isotype specific immune response in rats infected with Fasciola hepatica. Vet. Parasitol., 79: 229-237
31. Piedrafita, D., Parsons, J. C., Sandeman, R. M., Wood, P. R., Estuningsih, S. E., Partoutomo, S., Spithill, T. W. (2001): Antibody-dependent cell-mediated cytotoxicity to newly excysted juvenile Fasciola hepatica in vitro is mediated by reactive nitrogen intermediates. Parasit. Immunol., 23: 473-482
32. Poitou, I., Baeza, E., Boulard, C. (1992): Humoral and cellular immune responses in rats during a primary infestation with Fasciola hepatica. Vet. Parasitol., 45: 59-71
33. Poitou, I., Baeza, E., Boulard, C. (1993): Kinetic responses of parasite-specific antibody isotypes, blood leukocyte pattern and lymphocyte subsets in rats during primary infestation with Fasciola hepatica. Vet. Parasitol., 49, 179-190
34. Rossjohn, J., Feil, S. C., Wilce, M. C. J., Sexton, J. L., Spithill, T. W., Parker, M. W. (1997): Crystallization, structural determination and analysis of a novel parasite vaccine candidate: Fasciola hepatica glutathione S-transferase. J. Mol. Biol., 273: 857-872
35. Sexton, J. L., Milner, A. R., Panaccio, M., Waddington, J., Wijffels, G., Chandler, D., Thompson, C., Wilson, L., Spithill, T. W., Mitchell, G. F., Campbell, N. J. (1990): Glutathione S- Transferase novel vaccine against Fasciola hepatica infection in sheep. J. Immunol., 145: 3905-3910
36. Smooker, P. M., Steeper, K. R., Drew, D. R., Strugnell, R. A., Spithill, T. W. (1999): Humoral responses in mice following vaccination with DNA encoding glutathione S transferase of Fasciola hepatica: effects of mode of vaccination and the cellular compartment of antigen expression. Parasit. Immunol., 21: 357-364
37. Spithill, T. W., Piedrafita, D., Smooker, P. M. (1997): Immunological approaches for the control of fasciolosis. Int. J. Parasitol., 27: 1221-1235
38. rd Cont. Mol. Biol. Diag. Int. Dis. Biotechnol. Warsaw
39. Tascon, R. E., Colston, M. J., Ragno, S. (1996): Vaccination against tuberculosis by DNA injection. Nature Med. 2: 888-892
40. Ulmer, J. B., Donelly, J. J., Parker, S. E. (1993): Heterologous protection against influenza by injection of DNA encoding a viral protein. Science, 259: 1745-1748
41. 2a antibodies around the parasites. Parasitol. Immunol., 20: 285-292
42. 1 responses against newly excysted juveniles. Parasitol. Immunol., 21: 243-251
43. Wȩdrychowicz, H., Turner, K. (1987): Antibody isotypes involved in local and systemic humoral responses of rats to primary infection with Fasciola hepatica. Acta Parasitol., 32: 369-382
44. Wijffels, G. L., Sexton, J. L., Salvatore, L., Pettitt, J. M., Humphris, D. C., Panaccio, M., Spithill, T. W. (1992): Primary sequence heterogeneity and tissue expression of glutathione S-transferses of Fasciola hepatica. Exp. Parasitol., 74: 87-99