Caspase inhibitors reduce the apoptotic but not necrotic component of kainate injury in primary murine cortical neuronal cultures

Neurological Research

Volumn 24, Issue 8, 2002, Pages 796-800

  Glassford, Alexander ^a   Lee, Jong Eun ^a,b   Xu, Lijun ^a   Giffard, Rona G ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Yonsei University College of Medicine   (South Korea)

Author keywords

Apoptosis; Cell death; Development; Excitotoxicity; Kainate; Primary culture

Indexed keywords

4 [5 (4 METHYL 1 PIPERAZINYL)[2,5' BI 1H BENZIMIDAZOL] 2' YL]PHENOL; 6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; BENZYLOXYCARBONYLASPARTYLGLUTAMYLVALYLASPARTYL FLUOROMETHYL KETONE; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE 3; CASPASE INHIBITOR; CYCLOHEXIMIDE; INTERLEUKIN 1BETA CONVERTING ENZYME; KAINIC ACID; PROPIDIUM IODIDE;

ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL COUNT; CELL VIABILITY; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; ENZYME INHIBITION; FETUS; IN VITRO STUDY; MOUSE; NERVE CELL CULTURE; NERVE CELL LESION; NERVE CELL NECROSIS; NEUROPROTECTION; NONHUMAN; PROTEIN SYNTHESIS;

ANIMALS; APOPTOSIS; BRAIN ISCHEMIA; CASPASES; CELL NUCLEUS; CELLS, CULTURED; CEREBRAL CORTEX; DOWN-REGULATION; ENZYME INHIBITORS; EXCITATORY AMINO ACID AGONISTS; FETUS; KAINIC ACID; MICE; NECROSIS; NERVE DEGENERATION; NEURONS; NEUROPROTECTIVE AGENTS; NEUROTOXINS;

EID: 0036898680     PISSN: 01616412     EISSN: None     Source Type: Journal    
DOI: 10.1179/016164102101200915     Document Type: Article

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