Design and use of a peptide nucleic acid for detection of the heteroplasmic low-frequency mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS) mutation in human mitochondrial DNA

Clinical Chemistry

Volumn 48, Issue 12, 2002, Pages 2155-2163

  Hancock, Diane K ^a   Schwarz, Frederick P ^a   Song, Fenhong ^b   Wong, Lee Jun C ^c   Levin, Barbara C ^a  

^a NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY   (United States)

^b UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE   (United States)

^c GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DOUBLE STRANDED DNA; MITOCHONDRIAL DNA;

ARTICLE; BASE PAIRING; BLOOD ANALYSIS; CLINICAL ARTICLE; CONCENTRATION PROCESS; CONCENTRATION RESPONSE; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DNA SEQUENCE; EARLY DIAGNOSIS; GENE AMPLIFICATION; GENE MUTATION; HUMAN; MELAS SYNDROME; METHODOLOGY; NUCLEIC ACID ANALYSIS; PATHOGENESIS; PROTEIN BINDING; PROTEIN ENGINEERING; SEQUENCE ANALYSIS; STANDARD; TEMPERATURE MEASUREMENT; THERMOSTABILITY; WILD TYPE;

EID: 0036893607     PISSN: 00099147     EISSN: None     Source Type: Journal    
DOI: 10.1093/clinchem/48.12.2155     Document Type: Article

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