Combined endurance/resistance training reduces plasma TNF-α receptor levels in patients with chronic heart failure and coronary artery disease

European Heart Journal

Volumn 23, Issue 23, 2002, Pages 1854-1860

  Conraads, Viviane M ^a   Beckers, P ^a   Bosmans, J ^a   De Clerck, L S ^a   Stevens, W J ^a   Vrints, C J ^a   Brutsaert, D L ^a  

^a ANTWERP UNIVERSITY HOSPITAL   (Belgium)

Author keywords

Chronic heart failure; Cytokines; Exercise training; Inflammation

Indexed keywords

CYTOKINE; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR 1; TUMOR NECROSIS FACTOR RECEPTOR 2;

ADULT; AGED; ANAEROBIC THRESHOLD; ANTIINFLAMMATORY ACTIVITY; ARTERY ENDOTHELIUM; ARTICLE; BLOOD SAMPLING; CLINICAL ARTICLE; CLINICAL TRIAL; CONGESTIVE CARDIOMYOPATHY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORONARY ARTERY DISEASE; CYTOKINE PRODUCTION; ENDURANCE; ENZYME LINKED IMMUNOSORBENT ASSAY; EXERCISE; FEMALE; HEART FAILURE; HUMAN; INFLAMMATION; MALE; OXYGEN CONSUMPTION; PERFORMANCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SKELETAL MUSCLE; TRAINING;

ADULT; AGED; AGED, 80 AND OVER; CORONARY DISEASE; CYTOKINES; EXERCISE THERAPY; EXERCISE TOLERANCE; FEMALE; HEART FAILURE, CONGESTIVE; HUMANS; INTERLEUKIN-6; MALE; MIDDLE AGED; OXYGEN CONSUMPTION; PHYSICAL ENDURANCE; RECEPTORS, TUMOR NECROSIS FACTOR;

EID: 0036892191     PISSN: 0195668X     EISSN: None     Source Type: Journal    
DOI: 10.1053/euhj.2002.3239     Document Type: Article

References (29)

1. Drexler H, Riede U, Münzel T, König H, Funke E, Just H. Alterations of skeletal muscle in chronic heart failure. Circulation 1992; 85: 1751-9.
2. Harrington D, Anker SD, Chua TP et al. Skeletal muscle function and its relation to exercise tolerance in chronic heart failure. J Am Coll Cardiol 1997; 30: 1758-64.
3. Ferrari R, Bachetti T, Agnoletti L, Comini L, Curello S. Endothelial function and dysfunction in heart failure. Eur Heart J 1998; 19: G41-G47.
4. Feldman AM, Combes A, Wagner D et al. The role of tumor necrosis factor in the pathophysiology of heart failure. J Am Coll Cardiol 2000; 35: 537-44.
5. Ferrari R, Bachetti T, Confortini R et al. Tumor necrosis factor soluble receptor in patients with various degrees of congestive heart failure. Circulation 1995; 92: 1479-86.
6. Rauchhaus M, Doehner W, Francis DP et al. Plasma cytokine parameters and mortality in patients with chronic heart failure. Circulation 2000; 102: 3060-7.
7. Deswal A, Petersen NJ, Feldman AM, Young JB, White BG, Mann DL. Cytokines and cytokine receptors in advanced heart failure. An analysis of the cytokine database from vesnarinone trial (VEST). Circulation 2001; 103: 2055-9.
8. Wielenga RP, Huisveld IA, Bol E et al. Safety and effects of physical training in chronic heart failure; results of the chronic heart failure and graded exercise study (CHANGE). Eur Heart J 1999; 20: 872-9.
9. European Heart Failure Training Group. Experience from controlled trials of physical training in chronic heart failure: Protocol and patient factors in effectiveness in the improvement in exercise tolerance. Eur Heart J 1998; 19: 466-75.
10. Hambrecht R, Gielen S, Linke A et al. Effects of exercise training on left ventricular function and peripheral resistance in patients with chronic heart failure. A randomized trial. JAMA 2000; 283: 3095-101.
11. Adamopoulos S, Parissis JT, Karatzas D et al. Physical training modulates proinflammatory cytokines and soluble fas-soluble fas ligand system in patients with chronic heart failure. J Am Coll Cardiol 2002; 39: 653-63.
12. Adamopoulos S, Parissis J, Kroupis C et al. Physical training reduces peripheral markers of inflammation in patients with chronic heart failure. Eur Heart J 2001; 22: 791-7.
13. Larsen AI, Aukrust P, Aarsland T, Dickstein K. Effect of aerobic exercise training on plasma levels of tumor necrosis factor alpha in patients with heart failure. Am J Cardiol; 88: 805-8.
14. Maiorana A, O'Driscoll G, Cheetham C et al. Combined aerobic and resistance exercise training improves functional capacity and strength in CHF. J Appl Physiol 2000; 88: 1565-70.
15. Maiorana A, O'Driscoll G, Dembo L et al. Effect of aerobic and resistance exercise training on vascular function in heart failure. Am J Physiol Heart Circ Physiol 2000; 279: H1999-H2005.
16. Levine B, Kalman J, Mayer L, Fillit HM, Packer M. Elevated circulating levels of tumor necrosis factor in severe chronic heart failure. N Engl J Med 1990; 323: 236-41.
17. Torre-Amione G, Kapadia S, Benedict C, Oral H, Young JB, Mann DL. Proinflammatory cytokine levels in patients with depressed left ventricular ejection fraction: A report from the studies of left ventricular dysfunction (SOLVD). J Am Coll Cardiol 1996; 27: 1201-6.
18. Torre-Amione G, Kapadia S, Lee J et al. Tumor necrosis factor-α and tumor necrosis factor receptors in the failing human heart. Circulation 1996; 93: 704-11.
19. Adamopoulos S, Parissis JT, Kroupis C et al. Physical training reduces inflammatory markers of monocyte-endothelial cell adhesive interaction and improves endothelial function in chronic heart failure patients. Eur J Heart Fail 2001; 3 (Suppl. 1): S68.
20. Resnick N, Gimbrone MA Jr. Hemodynamic forces are complex regulators of endothelial gene expression. FASEB J 1995; 9: 874-82.
21. Varin R, Mulder P, Richard V et al. Exercise improves flow-mediated vasodilatation of skeletal muscle arteries in rats with chronic heart failure. Role of nitric oxide, prostanoids, and oxidant stress. Circulation 1999; 99: 2951-7.
22. Anker SD, Volterrani M, Egerer KR et al. Tumor necrosis factor alpha as a predictor of peak leg blood flow in patients with chronic heart failure. Q J Med 1998; 91: 199-203.
23. Agnoletti L, Curello S, Bachetti T et al. Serum from patients with severe heart failure down regulates eNOS and is proapoptotic: Role of tumor necrosis factor alpha. Circulation 1999; 100: 1983-91.
24. Linke A, Schoene N, Gielen S et al. Endothelial dysfunction in patients with chronic heart failure: Systemic effects of lower-limb exercise training. J Am Coll Cardiol 2001; 37: 392-7.
25. Adams V, Yu J, Möbius-Winkler S et al. Increased inducible nitric oxide synthase in skeletal muscle biopsies from patients with chronic heart failure. Biochem Mol Med 1997; 61: 152-60.
26. Adams V, Jiang H, Yu J et al. Apoptosis in skeletal myocytes of patients with chronic heart failure is associated with exercise intolerance. J Am Coll Cardiol 1999; 33: 959-65.
27. Corti A, Poiesi C, Merli S, Cassani G. Tumor necrosis factor (TNF) alpha quantification by ELISA and bioassay: Effects of TNF alpha-soluble TNF receptor (p55) complex dissociation during assay incubation. J Immunol Methods 1994; 177: 191-8.
28. Kapadia S, Torre-Amione G, Mann DL. Pitfalls in measuring cytokines. Ann Int Med 1994; 121: 149-50.
29. Dibbs Z, Thornby J, White BG, Mann DL. Natural variability of circulating levels of cytokines and cytokine receptors in patients with heart failure: Implications for clinical trials. J Am Coll Cardiol 1999; 33: 1935-42.