Role of c-Jun concentration in neuronal cell death

Journal of Neuroscience Research

Volumn 70, Issue 5, 2002, Pages 655-664

  Rössler, Oliver G ^a   Steinmüller, Lars ^a   Giehl, Klaus M ^a   Thiel, Gerald ^a  

^a SAARLAND UNIVERSITY   (Germany)

Author keywords

AP 1; C Fos; C Jun; Neuronal cell death

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; 4 HYDROXYTAMOXIFEN; DYE; ESTROGEN RECEPTOR; FORMAZAN; HYBRID PROTEIN; LEUCINE ZIPPER PROTEIN; PROTEIN C FOS; PROTEIN C JUN; TRANSCRIPTION FACTOR AP 1;

ALLELE; ARTICLE; CELL DEATH; CELL IMMORTALIZATION; CELL PROLIFERATION; CELL STRAIN; CELL SURVIVAL; CONTROLLED STUDY; DNA VECTOR; GENE ACTIVITY; GENETIC TRANSFECTION; HIPPOCAMPUS; HUMAN; HUMAN CELL; LIGAND BINDING; NERVE CELL NECROSIS; PHEOCHROMOCYTOMA CELL; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; TRANSCRIPTION INITIATION;

ANIMALS; CELL DEATH; CELL LINE, TRANSFORMED; CELL SURVIVAL; GENE EXPRESSION; GENES, REPORTER; HIPPOCAMPUS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MITOCHONDRIA; MITOGEN-ACTIVATED PROTEIN KINASES; NEURONS; OXIDATION-REDUCTION; PC12 CELLS; PROTO-ONCOGENE PROTEINS C-FOS; PROTO-ONCOGENE PROTEINS C-JUN; RATS; RECOMBINANT FUSION PROTEINS; TRANSCRIPTION FACTOR AP-1; TRANSCRIPTION, GENETIC;

EID: 0036892120     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/jnr.10447     Document Type: Article

References (39)

1. Angel P, Baumann I, Stein B, Delius H, Rahmsdorf HJ, Herrlich P. 1987. 12-O-tetradecanoyl-phorbol-13-acetate induction of the human collagenase gene is mediated by an inducible enhancer located in the 5′ flanking region. Mol Cell Biol 7:2256-2266.
2. Bossy-Wetzel E, Bakiri L, Yaniv M. 1997. Induction of apoptosis by the transcription factor c-Jun. EMBO J 16:1695-1709.
3. Behrens A, Sibilia M, Wagner EF. 1999. Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation. Nature Genet 21:326-329.
4. Chiu R, Boyle WJ, Meek J, Smeal T, Hunter T, Karin M. 1988. The c-fos protein interacts with c-jun/AP-1 to stimulate transcription of AP-1 responsive genes. Cell 54:541-552.
5. Cibelli G, Policastro V, Rössler OG, Thiel G. 2002. Nitric oxide-induced programmed cell death in human neuroblastoma cells is accompanied by the synthesis of Egr-1, a zinc finger transcription factor. J Neurosci Res 67:450-460.
6. Curran T, Franza BR Jr. 1988. Fos and jun: The AP-1 connection. Cell 55:395-397.
7. Davis RJ. 2000. Signal transduction by the JNK group of MAP kinases. Cell 103:239-252.
8. Dragunow M, Xu R, Walton M, Woodgate A-M, Lawlor P, MacGibbon GA, Young D, Gibbons H, Lipski J, Muravlev A, Pearson A, During M. 2000. c-Jun promotes neurite outgrowth and survival in PC12 cells. Brain Res Mol Brain Res 83:20-33.
9. Groot M, Boxer LM, Thiel G. 2000. Nerve growth factor- and epidermal growth factor-regulated gene transcription in PC12 pheochromocytoma and INS-1 insulinoma cells. Eur J Cell Biol 79:924-935.
10. Halazonetis TD, Georgopoulos K, Greenberg ME, Leder P. 1988. c-jun dimerizes with itself and with c-fos, forming complexes of different DNA binding affinities. Cell 55:917-924.
11. Ham J, Babij C, Whitfield J, Pfarr CM, Lallemand D, Yaniv M, Rubin LL. 1995. A c-Jun dominant negative mutant protects sympathetic neurons against programmed cell death. Neuron 14:927-939.
12. Ham J, Eilers A, Whitfield J, Neame SJ, Shah B. 2000. c-Jun and the transcriptional control of neuronal apoptosis. Biochem Pharmacol 60: 1015-1021.
13. Harper SJ, LoGrasso P. 2001. Signalling for survival and death in neurons: The role of stress-activated kinases, JNK and p38. Cell Signal 13:299-310.
14. Hawley RG, Lieu FHL, Fong AZC, Hawley TS. 1994. Versatile retroviral vetcors for potential use in gene therapy. Gene Therapy 1:136-138.
15. Hilberg F, Aguzzi A, Howells N, Wagner EF. 1993. c-jun is essential for normal mouse development and hepatogenesis. Nature 365:179-181.
16. Johnson NL, Gardner AM, Diener KM, Lange-Carter CA, Gleavy J, Jarpe MB, Minden A, Karin M, Zon LI, Johnson GL. 1996. Signal transduction pathways regulated by mitogen-activated/extracellular response kinase kinase kinase induce cell death. J Biol Chem 271:3229-3237.
17. Jüngling S, Cibelli G, Czardybon M, Gerdes H-H, Thiel G. 1994. Differential regulation of chromogranin B and synapsin I gene promoter activity by cyclic AMP and cyclic AMP-dependent protein kinase. Eur J Biochem 226:925-935.
18. Le-Niculescu H, Bonfoco E, Kasuya Y, Claret F-X, Green DR, Karin M. 1999. Withdrawal of survival factors results in activation of the JNK pathway in neuronal cells leading to Fas ligand induction and cell death. Mol Cell Biol 19:751-763.
19. Leppä S, Bohmann D. 1999. Diverse functions of JNK signaling and c-jun in stress response and apoptosis. Oncogene 18:6158-6162.
20. Leppä S, Eriksson M, Saffrich R, Ansorge W, Bohmann D. 2001. Complex functions of AP-1 transcription factors in differentiation and survival of PC12 cells. Mol Biol Cell 21:4369-4378.
21. Littlewood TD, Hancock DC, Danielian PS, Parker MG, Evan GI. 1995. A modified estrogen receptor ligand-binding domain as an improved switch for the regulation of heterologous proteins. Nucleic Acids Res 23:1686-1690.
22. Luo Y, Umegaki H, Wang X, Abe R, Roth GS. 1998. Dopamine induces apoptosis through an oxidation-involved SAPK/JNK activation pathway. J Biol Chem 273:3756-3764.
23. Maher P, Schubert D. 2000. Signaling by reactive oxygen species in the nervous system. Cell Mol Life Sci 57:1287-1305.
24. Miller AD, Rosman GJ. 1989. Improved retroviral vectors for gene transfer and expression. BioTechniques 7:980-990.
25. Minden A, Lin A, McMahon M, Lange-Carter C, Dérijard B, Davis RJ, Johnson GL, Karin M. 1994. Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MEKK. Science 266:1719-1794.
26. Picard D. 1993. Steroid-binding domains for regulating the function of heterologous proteins in cis. Trends Cell Biol 3:278-280.
27. Potapova O, Basu S, Mercola D, Holbrook NJ. 2001. Protective role for c-Jun in the cellular response to DNA damage. J Biol Chem 276:28546-28553.
28. Rauscher FJ 3rd, Voulalas PJ, Franza BR Jr, Curran T. 1988. Fos and jun bind cooperatively to the AP-1 site: Reconstitution in vitro. Genes Dev 2:1687-1699.
29. Shaulian E, Karin M. 2001. AP-1 in cell proliferation and survival. Oncogene 20:2390-2400.
30. Steinmüller L, Cibelli G, Moll JR, Vinson C, Thiel G. 2001. Regulation and composition of activator protein1 (AP-1) transcription factors controlling collagenase and c-Jun promoter activities. Biochem J 360:599-607.
31. Thiel G, Greengard P, Südhof TC. 1991. Characterization of tissue-specific transcription by the human synapsin I gene promoter. Proc Natl Acad Sci USA 88:3431-3435.
32. Thiel G, Kaufinann K, Magin A, Lietz M, Bach K, Cramer M. 2000. The human transcriptional repressor protein NAB1: Expression and biological activity. Biochim. Biophys. Acta 1493:289-301.
33. Tournier C, Hess P, Yang DD, Xu J, Turner TK, Nimnual A, Bar-Sagi D, Jones SN, Flavell RA, Davis RJ. 2000. Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway. Science 288:870-874.
34. Valavanis C, Hu Y, Yang Y, Osborne BA, Chouaib S, Greene L, Ashwell JD, Schwartz LM. 2001. Model cell lines for the study of apoptosis in vitro. Meth Cell Biol 66:418-436.
35. van Dam H, Duyndam M, Rottier R, Bosch A, de Vries-Smits L, Herrlich P, Zantema A, Angel P, van der Eb AJ. 1993. Heterodimer formation of cJun and ATF-2 is responsible for induction of c-jun by the 243 amino acid adenovirus E1A protein. EMBO J 12:479-487.
36. Watson A, Eilers A, Lallemand D, Kyriakis J, Rubin LL, Ham J. 1998. Phosphorylation of c-Jun is necessary for apoptosis induced by survival signal withdrawal in cerebellar granule neurons. J Neurosci 18:751-762.
37. Whitfield J, Neame SJ, Paquet L, Bernard O, Ham J. 2001. Dominant-negative c-Jun promotes neuronal survival by reducing BIM expression and inhibiting mitochondrial cytochrome c release. Neuron 29:629-643.
38. Wisdom R, Johnson RS, Moore C. 1999. c-Jun regulates cell cycle progression and apoptosis by distinct mechanisms. EMBO J 18:188-197.
39. Yang DD, Kuan C-Y, Whitmarsh AJ, Rincón M, Zheng TS, Davis RJ, Rakic P, Flavell RA. 1997. Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene. Nature 389:865-870.