Upregulation of NHE3 is associated with compensatory cell growth response in young uninephrectomized rats

American Journal of Physiology - Renal Physiology

Volumn 283, Issue 6 52-6, 2002, Pages

  Girardi, Adriana C C ^a   Rocha, Roberto O ^a   Britto, Luiz R G ^a   Rebouças, Nancy A ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Cell proliferation; Hyperplasia; Renal proximal tubule; S3226; Type 3 sodium hydrogen exchanger; Uninephrectomy

Indexed keywords

BROXURIDINE; MESSENGER RNA; SODIUM PROTON EXCHANGE PROTEIN 3;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APICAL MEMBRANE; ARTICLE; BRUSH BORDER; CELL GROWTH; CONTROLLED STUDY; GENE ACTIVATION; GENE EXPRESSION REGULATION; KIDNEY CORTEX; KIDNEY DEVELOPMENT; KIDNEY MASS; KIDNEY PROXIMAL TUBULE; MALE; NEPHRECTOMY; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; RAT; WESTERN BLOTTING;

EID: 0036889859     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00010.2002     Document Type: Article

References (41)

1. WAF1/CIP1 save the kidney by limiting compensatory renal growth? Proc Natl Acad Sci USA 96: 10551-10553, 1999.
2. Amemiya M, Loffing J, Lotscher M, Kaissling B, Alpern RJ, and Moe OW. Expression of NHE-3 in the apical membrane of rat renal proximal tubule and thick ascending limb. Kidney Int 48:1206-1215, 1995.
3. Biemesderfer D, Rutherford PA, Nagy T, Pizzonia JH, Abu-Alfa AK, and Aronson PS. Monoclonal antibodies for high-resolution localization of NHE3 in adult and neonatal rat kidney. Am J Physiol Renal Physiol 273: F289-F299, 1997.
4. Britto LRG, Keyser KT, Lindstrom JM, and Karten HJ. Immunohistochemical localization of nicotinic acetylcholine receptor subunits in the mesencephalon and diencephalon of the chick (Gallus gallus). J Comp Neurol 317: 325-340, 1992.
5. + exchange in brush border vesicles from dogs with renal failure. Am J Physiol Renal Fluid Electrolyte Physiol 243: F293-F299, 1982.
6. Cortes P, Levin NW, and Martin PR. Ribonucleic acid synthesis in the renal cortex at the initiation of compensatory growth. Biochem J 158: 457-470, 1976.
7. Fine LG. The biology of renal hypertrophy. Kidney Int 29: 619-634, 1986.
8. Fine LG and Bradley T. Adaptation of proximal tubular structure and function: Insights into compensatory renal hypertrophy. Federation Proc 44: 2724-2727, 1985.
9. Fine LG and Norman J. Cellular events in renal hypertrophy. Annu Rev Pharmacol 51: 19-32, 1989.
10. Girardi ACC, Rocha RO, and Rebouças NA. The Na/H exchanger NHE3 expression in kidney undergoing hypertrophy (Abstract). J Am Soc Nephrol 4A: 17, 2001.
11. Girardi AC, Titan SMO, Malnic G, and Rebouças NA. Chronic effect of parathyroid hormone on Na/H exchanger type 3 isoform protein and mRNA in rat renal proximal tubules. Kidney Int 58: 1623-1631, 2000.
12. Grantham JJ, Grantham JA, Donoso VS, and Cragoe EJ Jr. Effect of amiloride on the compensatory renal growth that follows uninephrectomy in mice. J Lab Clin Med 114: 129-134, 1989.
13. + exchange in renal microvillus vesicles. Role of dietary protein and uninephrectomy. J Clin Invest 74: 1979-1987, 1984.
14. Hayslett JP. Functional adaptation to reduction of renal mass. Physiol Rev 59: 137-169, 1979.
15. Hayslett JP, Kashgarian M, and Epstein FH. Functional correlates of compensatory renal hypertrophy. J Clin Invest 47: 774-782, 1968.
16. Hropot M, Juretschke HP, Langer KH, and Schwark JR. S3226, a novel NHE3 inhibitor, attenuates ischemia-induced acute renal failure in rats. Kidney Int 60: 2283-2289, 2001.
17. Karp R, Brasel JA, and Winick M. Compensatory kidney growth after uninephrectomy in adult and infant rats. Am J Dis Child 121: 186-188, 1971.
18. Kaufman JM, DiMeola JH, Siegel NJ, Lytton B, Kashgarian M, and Hayslett JP. Compensatory adaptation of structure and function following progressive renal ablation. Kidney Int 6: 10-17, 1974.
19. Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 259: 680-685, 1970.
20. Lorenz JN, Schultheis PJ, Traynor T, Shull GE, and Schnermann J. Micropuncture analysis of single-nephron function in NHE3-deficient mice. Am J Physiol Renal Physiol 277: F447-F453, 1999.
21. Lowry OH, Rosebrough NJ, Farr AL, and Randall RG. Protein measurement with the Folin phenol reagent. J Biol Chem 193: 265-275, 1951.
22. + exchange after uninephrectomy but does not suppress hypertrophy. Am J Physiol Renal Fluid Electrolyte Physiol 263: F328-F334, 1992.
23. + exchanger. J Biol Chem 260: 12586-12592, 1985.
24. WAF1/CIP1 gene ameliorates progression to chronic renal failure. Proc Natl Acad Sci USA 96: 10830-10835, 1999.
25. Michael S, Gorenc T, Hershberger RE, Stork PJS, Steyger PS, and Roberts CT Jr. Extracellular signal-regulated protein kinase activation is required for the anti-hypertrophic effect of atrial natriuretic factor in neonatal rat ventricular myocytes. J Biol Chem 274: 24858-24864, 1999.
26. Mulroney SE, Haramati A, Werner H, Bondy C, Roberts CT Jr, and LeRoith D. Altered expression of insulin-like growth factor-I (IGF-I) and IGF receptor genes after unilateral nephrectomy in immature rats. Endocrinology 130: 249-256, 1992.
27. Mulroney SE, Koenig JI, Csikos T, Pesce C, Striker L, LeRoith D, and Haramati A. Temporal changes in insulin-like growth factor I, c-fos, and c-jun gene expression during hyperplastic kidney growth in weanling rats. Endocrinology 137: 839-845, 1996.
28. + antiport capacity of the rabbit remnant kidney. Am J Physiol Renal Fluid Electrolyte Physiol 249: F90-F98, 1985.
29. + antiport activity in hamster fibroblasts precludes growth at neutral and acidic pH. Proc Natl Acad Sci USA 81: 4833-4837, 1984.
30. Preisig P. What makes cells grow larger and how do they do it? Renal hypertrophy revisited. Exp Nephrol 7: 273-283, 1999.
31. Preisig P. A cell cycle dependent mechanism of renal tubule epithelial cell hypertrophy. Kidney Int 56: 1193-1198, 1999.
32. 3 symporter activities in chronic hyperfiltration. J Gen Physiol 97: 195-217, 1991.
33. Puissant C and Houdebine LM. An improvement of the single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Biotechniques 8: 148-149, 1990.
34. Salihagic A, Mackovic M, Banfic H, and Sabolic I. Short-term and long-term stimulation of Na-H exchange in cortical brush-border membranes during compensatory growth of the rat kidney. Pflügers Arch 413: 190-196, 1988.
35. + exchanger. Nature Genet 19: 282-285, 1998.
36. + exchanger subtype 3 in various cell types. Pflügers Arch 436: 797-800, 1998.
37. + antiporter (NHE-1) gene expression during growth, hypertrophy and proliferation of the rabbit cardiovascular system. J Mol Cell Cardiol 27: 729-742, 1995.
38. Threlfall G, Taylor DM, and Buck AT. Studies of the changes in growth and DNA synthesis in the rat kidney during experimentally induced renal hypertrophy. Am J Pathol 50: 1-14, 1967.
39. Wang T, Hropot M, Aronson PS, and Giebisch G. Role of NHE isoforms in mediating bicarbonate reabsorption along the nephron. Am J Physiol Renal Physiol 281: F1117-F1122, 2001.
40. Wang T, Yang CL, Abbiati T, Schultheis PJ, Shull GE, Giebisch G, and Aronson PS. Mechanism of proximal tubule bicarbonate absorption in NHE3 null mice. Am J Physiol Renal Physiol 277: F298-F302, 1999.
41. + exchange. Adaptation to metabolic acidosis. J Biol Chem 271: 32749-32752, 1996.