Location of abasic sites in oligodeoxynucleotides by tandem mass spectrometry and by a chemical cleavage initiated by an unusual reaction of the ODN with MALDI matrix

Journal of the American Society for Mass Spectrometry

Volumn 13, Issue 12, 2002, Pages 1418-1426

  Zhang, Li Kang ^a   Gross, Michael L ^a  

^a WASHINGTON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DERIVATIVES; DESORPTION; IONIZATION; IONS; MASS SPECTROMETRY; ORGANIC ACIDS;

ABASIC SITES;

PROTEINS;

ACID; ANTHRALINIC ACID; HYDRAZONE DERIVATIVE; OLIGODEOXYNUCLEOTIDE; SCHIFF BASE; UNCLASSIFIED DRUG; 2,4 DINITROPHENYLHYDRAZONE; 2,4-DINITROPHENYLHYDRAZONE; DNA FRAGMENT; DNA GLYCOSYLTRANSFERASE; GLYCOSIDASE; OLIGONUCLEOTIDE; SOLVENT;

MASS SPECTROMETRY;

ARTICLE; CHEMICAL MODIFICATION; FRAGMENTATION REACTION; MASS SPECTROMETRY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; TANDEM MASS SPECTROMETRY; CHEMICAL MODEL; CHEMISTRY; DRUG STABILITY; ELECTROSPRAY MASS SPECTROMETRY; MOLECULAR WEIGHT;

DNA FRAGMENTATION; DNA GLYCOSYLASES; DRUG STABILITY; HYDRAZONES; MODELS, CHEMICAL; MOLECULAR WEIGHT; N-GLYCOSYL HYDROLASES; OLIGONUCLEOTIDES; SCHIFF BASES; SOLVENTS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 0036884689     PISSN: 10440305     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1044-0305(02)00701-8     Document Type: Article

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