Mitochondrial dysfunction in sepsis: A familiar song with new lyrics

Critical Care Medicine

Volumn 30, Issue 12, 2002, Pages 2780-2781

  Sayeed, Mohammed M ^a,b  

^a LOYOLA UNIVERSITY MEDICAL CENTER   (United States)

^b LOYOLA UNIVERSITY CHICAGO   (United States)

Author keywords

Cyclosporin A; Mitochondrial dysfunction; Sepsis

Indexed keywords

CYCLOSPORIN A; CYTOCHROME C; PYRUVIC ACID; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; CYCLOSPORIN; IMMUNOSUPPRESSIVE AGENT;

BLOOD PRESSURE; CLINICAL RESEARCH; DISORDERS OF MITOCHONDRIAL FUNCTIONS; EDITORIAL; HUMAN; MEMBRANE PERMEABILITY; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; OXYGEN TISSUE LEVEL; PATHOGENESIS; PRIORITY JOURNAL; SEPSIS; ANIMAL; CAT; DRUG EFFECT; INTRACELLULAR MEMBRANE; METABOLISM; NOTE; PATHOPHYSIOLOGY; PERMEABILITY; ULTRASTRUCTURE;

ANIMALS; CATS; CYCLOSPORINE; HUMANS; IMMUNOSUPPRESSIVE AGENTS; INTRACELLULAR MEMBRANES; MITOCHONDRIA; MITOCHONDRIAL DISEASES; PERMEABILITY; SEPSIS;

EID: 0036884662     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/00003246-200212000-00030     Document Type: Editorial

References (14)

1. Sayeed MM, Baue AE: Mitochondrial metabolism of succinate, beta-hydroxybutyrate, and alpha-ketoglutarate in hemorrhagic shock. Am J Physiol 1971; 220:1275-1281
2. Moss GS, Erve PP, Schumer W: Effect of endotoxin on mitochondrial respiration. Surg Forum 1969; 20:24-25
3. Reed PC, Erve PR, Das Gupta TK, et al: Endotoxemic effect of Escherichia coli on cardiac and skeletal muscle mitochondria. Surg Forum 1970; 21:13-14
4. White RR, Mela L, Bacalzo LV Jr, et al: Hepatic ultrastructure in endotoxemia, hemorrhage, and hypoxia: Emphasis on mitochondrial changes. Surgery 1973; 4:525-534
5. Asher EF, Garrison RN, Ratcliffe DJ, et al: Endotoxin, cellular function, and nutrient blood flow. Arch Surg 1983; 118:441-445
6. Fink MP: Cytopathic hypoxia. Mitochondrial dysfunction as mechanism contributing to organ dysfunction in sepsis. Crit Care Clin 2001; 17:219-237
7. Crouser ED, Julian MW, Joshi MS, et al: Cyclosporin A ameliorates mitochondrial ultrastructural injury in the ileum during acute endotoxemia. Crit Care Med 2002; 30:2722-2728
8. Colli A, Basso E, Petronilli V, et al: Interactions of cyclophilin with the mitochondrial inner membrane and regulation of the permeability transition pore, a cyclosporin A-sensitive channel. J Biol Chem 1996; 271:2185-2192
9. Lemeshko V: Cytochrome c sorption-desorption effects on the external NABH oxidation by mitochondria. J Biol Chem 2002; 277:17751-17757
10. Kantrow SP, Tatro LG, Piantadosi CA: Oxidative stress and adenine nucleotide control of mitochondrial permeability transition. Free Radic Biol Med 2000; 28:251-260
11. Crouser EB, Julian MW, Blaho BV, et al: Endotoxin-induced mitochondrial damage correlates with impaired respiratory activity. Crit Care Med 2002; 30:276-284
12. Canton M, Caffieri S, Dall' Acqua F, et al: PLTVA-induced apoptosis involves mitochondrial dysfunction caused by the opening of the permeability transition pore. FEBS Lett 2002; 522:168-172
13. Lin DT, Lechleiter JD: Mitochondrial targeted cyclophilin D protects cells from cell death by peptidyl prolyl isomeriation. J Biol Chern 2002; 277:31134
14. Waldmeier PC, Feldtrauer JJ, Qian T, et al: Inhibition of the mitochondrial permeability transition by the nonimmunosuppressive cyclosporin derivative. Mol Pharmacol 2002; 62:22-29