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Volumn 107, Issue 4, 2002, Pages 507-516

Opposing roles of activator protein-1 and CCAAT/enhancer binding protein β in the regulation of inducible granulysin gene expression in a human monocytic cell line, THP-1

Author keywords

[No Author keywords available]

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN BETA; GRANULYSIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; OLIGONUCLEOTIDE; TOLL LIKE RECEPTOR 2; TRANSCRIPTION FACTOR AP 1; ANTIINFECTIVE AGENT; GNLY PROTEIN, HUMAN; T LYMPHOCYTE ANTIGEN;

EID: 0036884082     PISSN: 00192805     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2567.2002.01524.x     Document Type: Article
Times cited : (9)

References (54)
  • 2
    • 0025119945 scopus 로고
    • A cDNA clone expressed in natural killer and T cells that likely encodes a secreted protein
    • Yabe T, McSherry C, Bach FH, Houchins JP. A cDNA clone expressed in natural killer and T cells that likely encodes a secreted protein. J Exp Med 1990; 172:1159-63.
    • (1990) J Exp Med , vol.172 , pp. 1159-1163
    • Yabe, T.1    McSherry, C.2    Bach, F.H.3    Houchins, J.P.4
  • 3
    • 0031569218 scopus 로고    scopus 로고
    • Processing, subcellular localization, and function of 519 (granulysin), a human late T cell activation molecule with homology to small, lytic, granule proteins
    • Pena SV, Hanson DA, Carr BA, Goralski TJ, Krensky AM. Processing, subcellular localization, and function of 519 (granulysin), a human late T cell activation molecule with homology to small, lytic, granule proteins. J Immunol 1997; 158:2680-8.
    • (1997) J Immunol , vol.158 , pp. 2680-2688
    • Pena, S.V.1    Hanson, D.A.2    Carr, B.A.3    Goralski, T.J.4    Krensky, A.M.5
  • 4
    • 0032475823 scopus 로고    scopus 로고
    • An antimicrobial activity of cytolytic T cells mediated by granulysin
    • Stenger S, Hanson DA, Teitelbaum R et al. An antimicrobial activity of cytolytic T cells mediated by granulysin. Science 1998; 282:121-5.
    • (1998) Science , vol.282 , pp. 121-125
    • Stenger, S.1    Hanson, D.A.2    Teitelbaum, R.3
  • 6
    • 0034671831 scopus 로고    scopus 로고
    • Granulysin, a T cell product, kills bacteria by altering membrane permeability
    • Ernst WA, Thoma-Uszynski S, Teitelbaum R et al. Granulysin, a T cell product, kills bacteria by altering membrane permeability. J Immunol 2000; 165:7102-8.
    • (2000) J Immunol , vol.165 , pp. 7102-7108
    • Ernst, W.A.1    Thoma-Uszynski, S.2    Teitelbaum, R.3
  • 7
    • 0032529629 scopus 로고    scopus 로고
    • Granulysin-induced apoptosis. I. Involvement of at least two distinct pathways
    • Gamen S, Hanson DA, Kaspar A, Naval J, Krensky AM, Anel A. Granulysin-induced apoptosis. I. Involvement of at least two distinct pathways. J Immunol 1998; 161:1758-64.
    • (1998) J Immunol , vol.161 , pp. 1758-1764
    • Gamen, S.1    Hanson, D.A.2    Kaspar, A.3    Naval, J.4    Krensky, A.M.5    Anel, A.6
  • 8
    • 0035399927 scopus 로고    scopus 로고
    • A distinct pathway of cell-mediated apoptosis initiated by granulysin
    • Kaspar AA, Okada S, Kumar J et al. A distinct pathway of cell-mediated apoptosis initiated by granulysin. J Immunol 2001; 167:350-6.
    • (2001) J Immunol , vol.167 , pp. 350-356
    • Kaspar, A.A.1    Okada, S.2    Kumar, J.3
  • 9
    • 0035421688 scopus 로고    scopus 로고
    • A role of the mitochondrial apoptosis-inducing factor in granulysin-induced apoptosis
    • Pardo J, Perez-Galan P, Gamen S et al. A role of the mitochondrial apoptosis-inducing factor in granulysin-induced apoptosis. J Immunol 2001; 167:1222-9.
    • (2001) J Immunol , vol.167 , pp. 1222-1229
    • Pardo, J.1    Perez-Galan, P.2    Gamen, S.3
  • 10
    • 0031966637 scopus 로고    scopus 로고
    • Differential regulation of human NK cell-associated gene expression following activation by IL-2, IFN-α and PMA/ionomycin
    • Mori S, Jewett A, Cavalcanti M, Murakami-Mori K, Nakamura S, Bonavida B. Differential regulation of human NK cell-associated gene expression following activation by IL-2, IFN-α and PMA/ionomycin. Int J Oncol 1998; 12:1165-70.
    • (1998) Int J Oncol , vol.12 , pp. 1165-1170
    • Mori, S.1    Jewett, A.2    Cavalcanti, M.3    Murakami-Mori, K.4    Nakamura, S.5    Bonavida, B.6
  • 11
    • 0034653395 scopus 로고    scopus 로고
    • Role of CCAAT/enhancer-binding protein site in transcription of human neutrophil peptide-1 and -3 defensin genes
    • Tsutsumi-Ishii Y, Hasebe T, Nagaoka I. Role of CCAAT/enhancer-binding protein site in transcription of human neutrophil peptide-1 and -3 defensin genes. J Immunol 2000; 164:3264-73.
    • (2000) J Immunol , vol.164 , pp. 3264-3273
    • Tsutsumi-Ishii, Y.1    Hasebe, T.2    Nagaoka, I.3
  • 12
    • 0036136328 scopus 로고    scopus 로고
    • Regulation of human β-defensin-2 in gingival epithelial cells: The involvement of mitogen-activated protein kinase pathways, but not the NF-kB transcription factor family
    • Krisanaprakornkit S, Kimball JR, Dale BA. Regulation of human β-defensin-2 in gingival epithelial cells: the involvement of mitogen-activated protein kinase pathways, but not the NF-kB transcription factor family. J Immunol 2002; 168:316-24.
    • (2002) J Immunol , vol.168 , pp. 316-324
    • Krisanaprakornkit, S.1    Kimball, J.R.2    Dale, B.A.3
  • 13
    • 0036142740 scopus 로고    scopus 로고
    • NF-kB-mediated transcriptional regulation of human β-defensin-2 gene following lipopolysaccharide stimulation
    • Tsutsumi-Ishii Y. Nagaoka I. NF-kB-mediated transcriptional regulation of human β-defensin-2 gene following lipopolysaccharide stimulation. J Leukoc Biol 2002; 71:154-62.
    • (2002) J Leukoc Biol , vol.71 , pp. 154-162
    • Tsutsumi-Ishii, Y.1    Nagaoka, I.2
  • 14
    • 0035168317 scopus 로고    scopus 로고
    • Acholeplasma laidlawii up-regulates granulysin gene expression via transcription factor activator protein-1 in a human monocytic cell line, THP-1
    • Kida Y, Kuwano K, Zhang Y, Arai S. Acholeplasma laidlawii up-regulates granulysin gene expression via transcription factor activator protein-1 in a human monocytic cell line, THP-1. Immunology 2001; 104:324-32.
    • (2001) Immunology , vol.104 , pp. 324-332
    • Kida, Y.1    Kuwano, K.2    Zhang, Y.3    Arai, S.4
  • 15
    • 0034651729 scopus 로고    scopus 로고
    • Human toll-like receptor 2 mediates monocyte activation by Listeria monocytogenes, but not by group B streptococci or lipopolysaccharide
    • Flo TH, Halaas O, Lien E, Ryan L, Teti G, Golenbock DT, Sundan A, Espevik T. Human toll-like receptor 2 mediates monocyte activation by Listeria monocytogenes, but not by group B streptococci or lipopolysaccharide. J Immunol 2000; 164:2064-9.
    • (2000) J Immunol , vol.164 , pp. 2064-2069
    • Flo, T.H.1    Halaas, O.2    Lien, E.3    Ryan, L.4    Teti, G.5    Golenbock, D.T.6    Sundan, A.7    Espevik, T.8
  • 16
    • 0030968406 scopus 로고    scopus 로고
    • Production of a T-cell clone which reacts with membrane proteins of Acholeplasma laidlawii
    • Kuwano K, Ono S, Akashi A, Ohishi M, Shigematsu H, Arai S. Production of a T-cell clone which reacts with membrane proteins of Acholeplasma laidlawii. Microbiol Immunol 1997; 41:261-4.
    • (1997) Microbiol Immunol , vol.41 , pp. 261-264
    • Kuwano, K.1    Ono, S.2    Akashi, A.3    Ohishi, M.4    Shigematsu, H.5    Arai, S.6
  • 17
    • 0026728698 scopus 로고
    • Genomic structure and alternative splicing of 519, a gene expressed late after T cell activation
    • Manning WC, O'Farrell S, Goralski TJ, Krensky AM. Genomic structure and alternative splicing of 519, a gene expressed late after T cell activation. J Immnnol 1992; 148:4036-42.
    • (1992) J Immnnol , vol.148 , pp. 4036-4042
    • Manning, W.C.1    O'Farrell, S.2    Goralski, T.J.3    Krensky, A.M.4
  • 19
  • 20
    • 0023751336 scopus 로고
    • Rapid and quantitative preparation of cytoplasmic RNA from small numbers of cells
    • Gough NM. Rapid and quantitative preparation of cytoplasmic RNA from small numbers of cells. Anal Biochem 1988; 173:93-5.
    • (1988) Anal Biochem , vol.173 , pp. 93-95
    • Gough, N.M.1
  • 21
    • 0025936177 scopus 로고
    • A liver-enriched transcriptional activator protein, LAP, and a transcriptional inhibitory protein, LIP, are translated from the same mRNA
    • Descombes P, Schibler U. A liver-enriched transcriptional activator protein, LAP, and a transcriptional inhibitory protein, LIP, are translated from the same mRNA. Cell 1991; 67:569-79.
    • (1991) Cell , vol.67 , pp. 569-579
    • Descombes, P.1    Schibler, U.2
  • 22
    • 0032487523 scopus 로고    scopus 로고
    • Type I interferon induces inhibitory 16-kD CCAAT/enhancer binding protein (C/EBP) β, repressing the HIV-1 long terminal repeat in macrophages: Pulmonary tuberculosis alters C/EBP expression, enhancing HIV-1 replication
    • Honda Y, Rogers L, Nakata K et al. Type I interferon induces inhibitory 16-kD CCAAT/enhancer binding protein (C/EBP) β, repressing the HIV-1 long terminal repeat in macrophages: pulmonary tuberculosis alters C/EBP expression, enhancing HIV-1 replication. J Exp Med 1998; 188:1255-65.
    • (1998) J Exp Med , vol.188 , pp. 1255-1265
    • Honda, Y.1    Rogers, L.2    Nakata, K.3
  • 23
    • 0030628417 scopus 로고    scopus 로고
    • Mycoplasmas: Sophisticated, reemerging, and burdened by their notoriety
    • Baseman JB, Tully JG. Mycoplasmas: sophisticated, reemerging, and burdened by their notoriety. Emerg Infect Dis 1997; 3:21-32.
    • (1997) Emerg Infect Dis , vol.3 , pp. 21-32
    • Baseman, J.B.1    Tully, J.G.2
  • 24
    • 0028030391 scopus 로고
    • Induced mouse spleen B-cell proliferation and secretion of immunoglobulin by lipid-associated membrane proteins of Mycoplasma fermentans incognitus and Mycoplasma penetrans
    • Feng SH, Lo SC. Induced mouse spleen B-cell proliferation and secretion of immunoglobulin by lipid-associated membrane proteins of Mycoplasma fermentans incognitus and Mycoplasma penetrans. Infect Immun 1994; 62:3916-21.
    • (1994) Infect Immun , vol.62 , pp. 3916-3921
    • Feng, S.H.1    Lo, S.C.2
  • 25
    • 0028085450 scopus 로고
    • Mycoplasma arginini TUH-14 membrane lipoproteins induce production of interleukin-1, interleukin-6, and tumor necrosis factor alpha by human monocytes
    • Herbelin A, Ruuth E, Delorme D, Michel-Herbelin C, Praz F. Mycoplasma arginini TUH-14 membrane lipoproteins induce production of interleukin-1, interleukin-6, and tumor necrosis factor alpha by human monocytes. Infect Immun 1994; 62:4690-4.
    • (1994) Infect Immun , vol.62 , pp. 4690-4694
    • Herbelin, A.1    Ruuth, E.2    Delorme, D.3    Michel-Herbelin, C.4    Praz, F.5
  • 26
    • 0027956306 scopus 로고
    • A 48-kilodalton Mycoplasma fermentans membrane protein induces cytokine secretion by human monocytes
    • Kostyal DA, Butler GH, Beezhold DH. A 48-kilodalton Mycoplasma fermentans membrane protein induces cytokine secretion by human monocytes. Infect Immun 1994; 62:3793-800.
    • (1994) Infect Immun , vol.62 , pp. 3793-3800
    • Kostyal, D.A.1    Butler, G.H.2    Beezhold, D.H.3
  • 27
    • 0345671672 scopus 로고    scopus 로고
    • Isolation, structure elucidation, and synthesis of a macrophage stimulatory lipopeptide from Mycoplasma fermentans acting at picomolar concentration
    • Muhlradt PF, Kiess M, Meyer H, Sussmuth R, Jung G. Isolation, structure elucidation, and synthesis of a macrophage stimulatory lipopeptide from Mycoplasma fermentans acting at picomolar concentration. J Exp Med 1997; 185:1951-8.
    • (1997) J Exp Med , vol.185 , pp. 1951-1958
    • Muhlradt, P.F.1    Kiess, M.2    Meyer, H.3    Sussmuth, R.4    Jung, G.5
  • 28
    • 0031664437 scopus 로고    scopus 로고
    • Structure and specific activity of macrophage-stimulating lipopeptides from Mycoplasma hyorhinis
    • Muhlradt PF, Kiess M, Meyer H, Sussmuth R, Jung G. Structure and specific activity of macrophage-stimulating lipopeptides from Mycoplasma hyorhinis. Infect Immun 1998; 66:4804-10.
    • (1998) Infect Immun , vol.66 , pp. 4804-4810
    • Muhlradt, P.F.1    Kiess, M.2    Meyer, H.3    Sussmuth, R.4    Jung, G.5
  • 29
    • 0034650420 scopus 로고    scopus 로고
    • Cutting edge: Preferentially the R-stereoisomer of the mycoplasmal lipopeptide macrophage-activating lipopeptide-2 activates immune cells through a toll-like receptor 2- and MyD88-dependent signaling pathway
    • Takeuchi O, Kaufmann A, Grote K, Kawai T, Hoshino K, Morr M, Muhlradt PF, Akira S. Cutting edge: preferentially the R-stereoisomer of the mycoplasmal lipopeptide macrophage-activating lipopeptide-2 activates immune cells through a toll-like receptor 2- and MyD88-dependent signaling pathway. J Immunol 2000; 164:554-7.
    • (2000) J Immunol , vol.164 , pp. 554-557
    • Takeuchi, O.1    Kaufmann, A.2    Grote, K.3    Kawai, T.4    Hoshino, K.5    Morr, M.6    Muhlradt, P.F.7    Akira, S.8
  • 30
    • 0035865058 scopus 로고    scopus 로고
    • Mycoplasma fermentans lipoprotein M161Ag-induced cell activation is mediated by Toll-like receptor 2: Role of N-terminal hydrophobic portion in its multiple functions
    • Nishiguchi M, Matsumoto M, Takao T et al. Mycoplasma fermentans lipoprotein M161Ag-induced cell activation is mediated by Toll-like receptor 2: role of N-terminal hydrophobic portion in its multiple functions. J Immunol 2001; 166:2610-16.
    • (2001) J Immunol , vol.166 , pp. 2610-2616
    • Nishiguchi, M.1    Matsumoto, M.2    Takao, T.3
  • 32
    • 0028986193 scopus 로고
    • Nf-κb: A lesson in family values
    • Thanos D, Maniatis T. NF-κB: a lesson in family values. Cell 1995; 80:529-32.
    • (1995) Cell , vol.80 , pp. 529-532
    • Thanos, D.1    Maniatis, T.2
  • 33
    • 0030271387 scopus 로고    scopus 로고
    • Nf-κb: Ten years after
    • Baeuerle PA, Baltimore D. NF-κB: ten years after. Cell 1996; 87:13-20.
    • (1996) Cell , vol.87 , pp. 13-20
    • Baeuerle, P.A.1    Baltimore, D.2
  • 34
    • 0026774239 scopus 로고
    • Selection of optimal κB/Rel DNA-binding motifs: Interaction of both subunits of NF-κB with DNA is required for transcriptional activation
    • Kunsch C, Ruben SM, Rosen CA. Selection of optimal κB/Rel DNA-binding motifs: interaction of both subunits of NF-κB with DNA is required for transcriptional activation. Mol Cell Biol 1992; 12:4412-21.
    • (1992) Mol Cell Biol , vol.12 , pp. 4412-4421
    • Kunsch, C.1    Ruben, S.M.2    Rosen, C.A.3
  • 35
    • 0025200592 scopus 로고
    • The 65-kD subunit of NF-κB is a receptor for IκB and a modulator of DNA-binding specificity
    • Urban MB, Baeuerle PA. The 65-kD subunit of NF-κB is a receptor for IκB and a modulator of DNA-binding specificity. Genes Dev 1990; 4:1975-84.
    • (1990) Genes Dev , vol.4 , pp. 1975-1984
    • Urban, M.B.1    Baeuerle, P.A.2
  • 36
    • 0025297353 scopus 로고
    • A nuclear factor for IL-6 expression (NF-IL6) is a member of a C/EBP family
    • Akira S, Isshiki H, Sugita T et al. A nuclear factor for IL-6 expression (NF-IL6) is a member of a C/EBP family. EMBO J 1990; 9:1897-906.
    • (1990) EMBO J , vol.9 , pp. 1897-1906
    • Akira, S.1    Isshiki, H.2    Sugita, T.3
  • 37
    • 0026501412 scopus 로고
    • Macrophage differentiation-specific expression of NF-IL6, a transcription factor for interleukin-6
    • Natsuka S, Akira S, Nishio Y, Hashimoto S, Sugita T, Isshiki H, Kishimoto T. Macrophage differentiation-specific expression of NF-IL6, a transcription factor for interleukin-6. Blood 1992; 79:460-6.
    • (1992) Blood , vol.79 , pp. 460-466
    • Natsuka, S.1    Akira, S.2    Nishio, Y.3    Hashimoto, S.4    Sugita, T.5    Isshiki, H.6    Kishimoto, T.7
  • 38
    • 0028170158 scopus 로고
    • C/EBPβ regulation of the tumor necrosis factor α gene
    • Pope RM, Leutz A, Ness SA. C/EBPβ regulation of the tumor necrosis factor α gene. J Clin Invest 1994; 94:1449-55.
    • (1994) J Clin Invest , vol.94 , pp. 1449-1455
    • Pope, R.M.1    Leutz, A.2    Ness, S.A.3
  • 39
    • 0030666222 scopus 로고    scopus 로고
    • Innate immunity: The virtues of a nonclonal system of recognition
    • Medzhitov R, Janeway CA, Innate immunity: the virtues of a nonclonal system of recognition. Cell 1997; 91:295-8.
    • (1997) Cell , vol.91 , pp. 295-298
    • Medzhitov, R.1    Janeway, C.A.2
  • 41
    • 0030831210 scopus 로고    scopus 로고
    • A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
    • Medzhitov R, Preston-Hurlburt P, Janeway CA. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature 1997; 388:394-7.
    • (1997) Nature , vol.388 , pp. 394-397
    • Medzhitov, R.1    Preston-Hurlburt, P.2    Janeway, C.A.3
  • 44
    • 0034457684 scopus 로고    scopus 로고
    • Cloning and characterization of a subfamily of human toll-like receptors: hTLR7, hTLR8 and hTLR9
    • Chuang TH, Ulevitch RJ. Cloning and characterization of a subfamily of human toll-like receptors: hTLR7, hTLR8 and hTLR9. Eur Cytokine Netw 2000; 11:372-8.
    • (2000) Eur Cytokine Netw , vol.11 , pp. 372-378
    • Chuang, T.H.1    Ulevitch, R.J.2
  • 45
    • 0034619794 scopus 로고    scopus 로고
    • A Toll-like receptor recognizes bacterial DNA
    • Hemmi HH, Takeuchi O, Kawai T et al. A Toll-like receptor recognizes bacterial DNA. Nature 2000; 408:740-5.
    • (2000) Nature , vol.408 , pp. 740-745
    • Hemmi, H.H.1    Takeuchi, O.2    Kawai, T.3
  • 46
    • 0035911644 scopus 로고    scopus 로고
    • Identification of hTLR10: A novel human Toll-like receptor preferentially expressed in immune cells
    • Chuang T, Ulevitch RJ. Identification of hTLR10: a novel human Toll-like receptor preferentially expressed in immune cells. Biochim Biophys Acta 2001; 1518:157-61.
    • (2001) Biochim Biophys Acta , vol.1518 , pp. 157-161
    • Chuang, T.1    Ulevitch, R.J.2
  • 47
    • 0033198204 scopus 로고    scopus 로고
    • Cutting edge: Inflammatory signaling by Borrelia burgdorferi lipoproteins is mediated by toll-like receptor 2
    • Hirschfeld M, Kirschning CJ, Schwandner R, Wesche H, Weis JH, Wooten RM, Weis JJ. Cutting edge: inflammatory signaling by Borrelia burgdorferi lipoproteins is mediated by toll-like receptor 2. J Immunol 1999; 163:2382-6.
    • (1999) J Immunol , vol.163 , pp. 2382-2386
    • Hirschfeld, M.1    Kirschning, C.J.2    Schwandner, R.3    Wesche, H.4    Weis, J.H.5    Wooten, R.M.6    Weis, J.J.7
  • 48
    • 0033580949 scopus 로고    scopus 로고
    • Peptidoglycan- and lipoteichoic acid-induced cell activation is mediated by toll-like receptor 2
    • Schwandner R, Dziarski R, Wesche H, Rothe M, Kirschning CJ. Peptidoglycan- and lipoteichoic acid-induced cell activation is mediated by toll-like receptor 2. J Biol Chem 1999; 274:17406-9.
    • (1999) J Biol Chem , vol.274 , pp. 17406-17409
    • Schwandner, R.1    Dziarski, R.2    Wesche, H.3    Rothe, M.4    Kirschning, C.J.5
  • 49
    • 0032509295 scopus 로고    scopus 로고
    • Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene
    • Poltorak A, He X, Smirnova I et al. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science 1998; 282:2085-8.
    • (1998) Science , vol.282 , pp. 2085-2088
    • Poltorak, A.1    He, X.2    Smirnova, I.3
  • 50
    • 0034680145 scopus 로고    scopus 로고
    • Toll-like receptors in the induction of the innate immune response
    • Aderem A, Ulevitch RJ. Toll-like receptors in the induction of the innate immune response. Nature 2000; 406:782-7.
    • (2000) Nature , vol.406 , pp. 782-787
    • Aderem, A.1    Ulevitch, R.J.2
  • 51
    • 0032983601 scopus 로고    scopus 로고
    • Lipid extract of Mycoplasma penetrans proteinase K-digested lipid-associated membrane proteins rapidly activates NF-κB and activator protein 1
    • Feng SH, Lo SC. Lipid extract of Mycoplasma penetrans proteinase K-digested lipid-associated membrane proteins rapidly activates NF-κB and activator protein 1. Infect Immun 1999; 67:2951-6.
    • (1999) Infect Immun , vol.67 , pp. 2951-2956
    • Feng, S.H.1    Lo, S.C.2
  • 52
    • 0025087266 scopus 로고
    • Mycoplasmas induce transcription and production of tumor necrosis factor in a monocytic cell line, THP-1, by a protein kinase C-independent pathway
    • Sugama K, Kuwano K, Furukawa M, Himeno Y, Satoh T, Arai S. Mycoplasmas induce transcription and production of tumor necrosis factor in a monocytic cell line, THP-1, by a protein kinase C-independent pathway. Infect Immun 1990; 58:3564-7.
    • (1990) Infect Immun , vol.58 , pp. 3564-3567
    • Sugama, K.1    Kuwano, K.2    Furukawa, M.3    Himeno, Y.4    Satoh, T.5    Arai, S.6
  • 54
    • 0035936836 scopus 로고    scopus 로고
    • Induction of direct antimicrobial activity through mammalian toll-like receptors
    • Thoma-Uszynski S, Stenger S, Takeuchi O et al. Induction of direct antimicrobial activity through mammalian toll-like receptors. Science 2001; 291:1544-7.
    • (2001) Science , vol.291 , pp. 1544-1547
    • Thoma-Uszynski, S.1    Stenger, S.2    Takeuchi, O.3


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