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Volumn 3, Issue 11, 2002, Pages 1660-1665

Enhancement of radiation therapy by vascular targeting agents

Author keywords

Radiotherapy; Tumor vasculature; Vascular targeting agent

Indexed keywords

5,6 DIMETHYLXANTHENONE 4 ACETIC ACID; ANG 453; ANTINEOPLASTIC AGENT; COMBRETASTATIN A4 PHOSPHATE; MITOFLAXONE; N ACETYLCOLCHINOL PHOSPHATE; PRODRUG; SERINE 2 METHOXY 5 [2 (3,4,5 TRIMETHOXYPHENYL)VINYL]ANILIDE; TIRAPAZAMINE; TUBULIN BINDING AGENT; UNCLASSIFIED DRUG;

EID: 0036881356     PISSN: 14724472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (16)

References (56)
  • 1
    • 0017370183 scopus 로고
    • Migration and proliferation of endothelial cells in preformed and newly formed blood vessels during tumor angiogenesis
    • Ausprunk D, Folkman J: Migration and proliferation of endothelial cells in preformed and newly formed blood vessels during tumor angiogenesis. Microvasc Res (1977) 14(1):53-65.
    • (1977) Microvasc Res , vol.14 , Issue.1 , pp. 53-65
    • Ausprunk, D.1    Folkman, J.2
  • 2
    • 0022648938 scopus 로고
    • How is blood vessel growth regulated in normal and neoplastic tissue?
    • Folkman J: How is blood vessel growth regulated in normal and neoplastic tissue? Cancer Res (1986) 46(2):467-473.
    • (1986) Cancer Res , vol.46 , Issue.2 , pp. 467-473
    • Folkman, J.1
  • 3
    • 0033213978 scopus 로고    scopus 로고
    • Tumor development under angiogenic signaling: A dynamical theory of tumor growth, treatment response, and postvascular dormancy
    • note
    • Hahnfeldt P, Panigrahy D, Folkman J, Hlatky L: Tumor development under angiogenic signaling: A dynamical theory of tumor growth, treatment response, and postvascular dormancy. Cancer Res (1999) 59(19):4770-4775. Comprehensive overview of tumor angiogenesis.
    • (1999) Cancer Res , vol.59 , Issue.19 , pp. 4770-4775
    • Hahnfeldt, P.1    Panigrahy, D.2    Folkman, J.3    Hlatky, L.4
  • 4
    • 0014865863 scopus 로고
    • Population kinetics of carcinoma cells, capillary endothelial cells, and fibroblasts in a transplanted mouse mammary tumor
    • Tannock IF: Population kinetics of carcinoma cells, capillary endothelial cells, and fibroblasts in a transplanted mouse mammary tumor. Cancer Res (1970) 30(10):2470-2476.
    • (1970) Cancer Res , vol.30 , Issue.10 , pp. 2470-2476
    • Tannock, I.F.1
  • 5
    • 0024408986 scopus 로고
    • Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: A review
    • Vaupel P, Kallinowski F, Okunieff P: Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: A review. Cancer Res (1989) 49(23):6449-6465.
    • (1989) Cancer Res , vol.49 , Issue.23 , pp. 6449-6465
    • Vaupel, P.1    Kallinowski, F.2    Okunieff, P.3
  • 6
    • 0002624330 scopus 로고    scopus 로고
    • Tumor oxygenation: Characterization and clinical implications
    • Smyth JF, Boogaerts MA, Ehmer BR (Eds), Marcel Dekker Inc, NY, USA; note
    • Vaupel P, Thews O, Hoeckel M: Tumor oxygenation: Characterization and clinical implications. In: Erythropoietin in Cancer Supportive Treatment. Smyth JF, Boogaerts MA, Ehmer BR (Eds), Marcel Dekker Inc, NY, USA (1996):205-239. A critical review of factors influencing tumor oxygenation.
    • (1996) Erythropoietin in Cancer Supportive Treatment , pp. 205-239
    • Vaupel, P.1    Thews, O.2    Hoeckel, M.3
  • 8
    • 0027261178 scopus 로고
    • Oxygen tension distribution are sufficient to explain the local response of human breast tumors treated with radiation alone
    • Okunieff P, Hoeckel M, Dunphy EP, Schlenger K, Knoop C, Vaupel P: Oxygen tension distribution are sufficient to explain the local response of human breast tumors treated with radiation alone. Int J Radiat Oncol Biol Phys (1993) 26(4):631-636.
    • (1993) Int J Radiat Oncol Biol Phys , vol.26 , Issue.4 , pp. 631-636
    • Okunieff, P.1    Hoeckel, M.2    Dunphy, E.P.3    Schlenger, K.4    Knoop, C.5    Vaupel, P.6
  • 10
    • 0029955072 scopus 로고    scopus 로고
    • Pretreatment oxygenation predicts radiation response in advanced squamous cell carcinoma of the head and neck
    • Nordsmark M, Overgaard M, Overgaard J: Pretreatment oxygenation predicts radiation response in advanced squamous cell carcinoma of the head and neck. Radiother Oncol (1996) 41(1):31-39.
    • (1996) Radiother Oncol , vol.41 , Issue.1 , pp. 31-39
    • Nordsmark, M.1    Overgaard, M.2    Overgaard, J.3
  • 11
    • 0032708195 scopus 로고    scopus 로고
    • Oxygenation of head and neck cancer: Changes during radiotherapy and impact on treatment outcome
    • Brizel DM, Dodge RK, Clough RW, Dewhirst MW: Oxygenation of head and neck cancer: Changes during radiotherapy and impact on treatment outcome. Radiother Oncol (1999) 53(2):113-117.
    • (1999) Radiother Oncol , vol.53 , Issue.2 , pp. 113-117
    • Brizel, D.M.1    Dodge, R.K.2    Clough, R.W.3    Dewhirst, M.W.4
  • 13
    • 0035717984 scopus 로고    scopus 로고
    • Metabolic mapping with bioluminescence: Basic and clinical relevance
    • Walenta S, Schroeder T, Mueller-Klieser W: Metabolic mapping with bioluminescence: Basic and clinical relevance. Biomol Eng (2002) 18(6):249-262.
    • (2002) Biomol Eng , vol.18 , Issue.6 , pp. 249-262
    • Walenta, S.1    Schroeder, T.2    Mueller-Klieser, W.3
  • 14
    • 0025974326 scopus 로고
    • Keynote address: The influence of microenvironmental factors on the activity of radiation and drugs
    • note
    • Durand RE: Keynote address: The influence of microenvironmental factors on the activity of radiation and drugs. Int J Radiat Oncol Biol Phys (1991) 20(2):253-258. Review describing the role of the tumor microenvironment in chemotherapy.
    • (1991) Int J Radiat Oncol Biol Phys , vol.20 , Issue.2 , pp. 253-258
    • Durand, R.E.1
  • 15
    • 0021216039 scopus 로고
    • Modification of chemotherapy by nitroimidazoles
    • Siemann DW: Modification of chemotherapy by nitroimidazoles. Int J Radiat Oncol Biol Phys (1984) 10(9):1585-1594.
    • (1984) Int J Radiat Oncol Biol Phys , vol.10 , Issue.9 , pp. 1585-1594
    • Siemann, D.W.1
  • 16
    • 0023902264 scopus 로고
    • Therapeutic attack of hypoxic cells of solid tumors: Presidential address
    • Sartorelli AC: Therapeutic attack of hypoxic cells of solid tumors: Presidential address. Cancer Res (1988) 48(4):775-778.
    • (1988) Cancer Res , vol.48 , Issue.4 , pp. 775-778
    • Sartorelli, A.C.1
  • 18
    • 0010170555 scopus 로고
    • Hypoxia induces DNA overreplication and enhances metastatic potential of murine tumor cells
    • Young SD, Marshall RS, Hill RP: Hypoxia induces DNA overreplication and enhances metastatic potential of murine tumor cells. Proc Natl Acad Sci USA (1988) 85(24):9533-9537.
    • (1988) Proc Natl Acad Sci USA , vol.85 , Issue.24 , pp. 9533-9537
    • Young, S.D.1    Marshall, R.S.2    Hill, R.P.3
  • 19
    • 0025025779 scopus 로고
    • Tumor progression: Potential role of unstable genomic changes
    • Hill RP: Tumor progression: Potential role of unstable genomic changes. Cancer Metastasis Rev (1990) 9(2):137-147.
    • (1990) Cancer Metastasis Rev , vol.9 , Issue.2 , pp. 137-147
    • Hill, R.P.1
  • 20
    • 0030067856 scopus 로고    scopus 로고
    • Hypoxic stress proteins: Survival of the fittest
    • note
    • Giaccia AJ: Hypoxic stress proteins: Survival of the fittest. Semin Radiat Oncol (1996) 6(1):46-58. Review describing the microenvironment's effect on tumor progression and genomic changes.
    • (1996) Semin Radiat Oncol , vol.6 , Issue.1 , pp. 46-58
    • Giaccia, A.J.1
  • 21
  • 22
    • 0035805046 scopus 로고    scopus 로고
    • Relationship of hypoxia to metastatic ability in rodent tumours
    • De Jaeger K, Kavanagh MC, Hill RP: Relationship of hypoxia to metastatic ability in rodent tumours. Br J Cancer (2001) 84(9):1280-1285.
    • (2001) Br J Cancer , vol.84 , Issue.9 , pp. 1280-1285
    • De Jaeger, K.1    Kavanagh, M.C.2    Hill, R.P.3
  • 24
    • 0026602628 scopus 로고
    • Coley's toxins in perspective
    • Starnes CO: Coley's toxins in perspective. Nature (1992) 357(6373):11-12.
    • (1992) Nature , vol.357 , Issue.6373 , pp. 11-12
    • Starnes, C.O.1
  • 25
    • 0002672326 scopus 로고
    • Vasculature as a target for tumour therapy
    • Hammersen F, Hudlicka O (Eds), Karger AG, Basel, Switzerland
    • Denekamp J: Vasculature as a target for tumour therapy. In: Progress in Applied Microcirculation. Hammersen F, Hudlicka O (Eds), Karger AG, Basel, Switzerland (1984) 4:28-38.
    • (1984) Progress in Applied Microcirculation , vol.4 , pp. 28-38
    • Denekamp, J.1
  • 26
    • 0027563591 scopus 로고
    • Review article: Angiogenesis, neovascular proliferation and vascular pathophysiology as targets for cancer therapy
    • note
    • Denekamp J: Review article: Angiogenesis, neovascular proliferation and vascular pathophysiology as targets for cancer therapy. Br J Radiol (1993) 66(783):181-196. Discussion of the fundamental basis of the vascular targeting concept.
    • (1993) Br J Radiol , vol.66 , Issue.783 , pp. 181-196
    • Denekamp, J.1
  • 27
    • 0032950870 scopus 로고    scopus 로고
    • Anti-vascular approaches to solid tumour therapy: Evaluation of combretastatin A4 phosphate
    • Chaplin DJ, Pettit GR, Hill SA: Anti-vascular approaches to solid tumour therapy: Evaluation of combretastatin A4 phosphate. Anticancer Res (1999) 19(1A):189-195.
    • (1999) Anticancer Res , vol.19 , Issue.1 A , pp. 189-195
    • Chaplin, D.J.1    Pettit, G.R.2    Hill, S.A.3
  • 28
    • 0032773566 scopus 로고    scopus 로고
    • Tumour vasculature as a target for cancer therapy
    • note
    • Chaplin DJ, Dougherty GJ: Tumour vasculature as a target for cancer therapy. Br J Cancer (1999) 80(Suppl 1):57-64. Description of various approaches that may be used in targeting tumor blood vessels.
    • (1999) Br J Cancer , vol.80 , Issue.SUPPL. 1 , pp. 57-64
    • Chaplin, D.J.1    Dougherty, G.J.2
  • 29
    • 0024335180 scopus 로고
    • Blood flow failure as a major determinant in the antitumor action of flavone acetic acid
    • Zwi LJ, Baguley BC, Gavin JB, Wilson WR: Blood flow failure as a major determinant in the antitumor action of flavone acetic acid. J Natl Cancer Inst (1989) 81(13):1005-1013.
    • (1989) J Natl Cancer Inst , vol.81 , Issue.13 , pp. 1005-1013
    • Zwi, L.J.1    Baguley, B.C.2    Gavin, J.B.3    Wilson, W.R.4
  • 30
    • 0034306873 scopus 로고    scopus 로고
    • Targeting tumor blood vessels: An adjuvant strategy for radiation therapy
    • note
    • Siemann DW, Warrington KH, Horsman MR: Targeting tumor blood vessels: An adjuvant strategy for radiation therapy. Radiother Oncol (2000) 57(1):5-12. Review outlining the basis for combining antivascular and anti-angiogenic approaches with radiation in cancer therapy.
    • (2000) Radiother Oncol , vol.57 , Issue.1 , pp. 5-12
    • Siemann, D.W.1    Warrington, K.H.2    Horsman, M.R.3
  • 32
    • 0026686247 scopus 로고
    • Antitumour responses to flavone-8-acetic acid and 5,6-dimethylxanthenone-4-acetic acid in immune deficient mice
    • Ching LM, Joseph WR, Baguley BC: Antitumour responses to flavone-8-acetic acid and 5,6-dimethylxanthenone-4-acetic acid in immune deficient mice. Br J Cancer (1992) 66(1):128-130.
    • (1992) Br J Cancer , vol.66 , Issue.1 , pp. 128-130
    • Ching, L.M.1    Joseph, W.R.2    Baguley, B.C.3
  • 33
    • 0029021607 scopus 로고
    • Preclinical in vitro and in vivo activity of 5,6-dimethylxanthenone-4-acetic acid
    • Laws AL, Matthew AM, Double JA, Bibby MC: Preclinical in vitro and in vivo activity of 5,6-dimethylxanthenone-4-acetic acid. Br J Cancer (1995) 71(6):1204-1209.
    • (1995) Br J Cancer , vol.71 , Issue.6 , pp. 1204-1209
    • Laws, A.L.1    Matthew, A.M.2    Double, J.A.3    Bibby, M.C.4
  • 34
    • 0026100365 scopus 로고
    • Potential antitumor agents. 61. Structure-activity relationships for in vivo colon 38 activity among disubstituted 9-oxo-9H-xanthene-4-acetic acids
    • Rewcastle GW, Atwell GJ, Li ZA, Baguley BC, Denny WA: Potential antitumor agents. 61. Structure-activity relationships for in vivo colon 38 activity among disubstituted 9-oxo-9H-xanthene-4-acetic acids. J Med Chem (1991) 34(1):217-222.
    • (1991) J Med Chem , vol.34 , Issue.1 , pp. 217-222
    • Rewcastle, G.W.1    Atwell, G.J.2    Li, Z.A.3    Baguley, B.C.4    Denny, W.A.5
  • 35
    • 0028234390 scopus 로고
    • Combining bioreductive drugs (SR 4233 or SN 23862) with the vasoactive agents flavone acetic acid or 5,6-dimethylxanthenone acetic acid
    • Cliffe S, Taylor ML, Rutland M, Baguley BC, Hill RP, Wilson WR: Combining bioreductive drugs (SR 4233 or SN 23862) with the vasoactive agents flavone acetic acid or 5,6-dimethylxanthenone acetic acid. Int J Radiat Oncol Biol Phys (1994) 29(2):373-377.
    • (1994) Int J Radiat Oncol Biol Phys , vol.29 , Issue.2 , pp. 373-377
    • Cliffe, S.1    Taylor, M.L.2    Rutland, M.3    Baguley, B.C.4    Hill, R.P.5    Wilson, W.R.6
  • 36
    • 0028280239 scopus 로고
    • Induction of tumor necrosis factor-α messenger RNA in human and murine cells by the flavone acetic analogue 5,6-dimethylxanthenone-4-acetic acid (NSC64088)
    • Ching LM, Joseph Wr, Crosier KE, Baguley BC: Induction of tumor necrosis factor-α messenger RNA in human and murine cells by the flavone acetic analogue 5,6-dimethylxanthenone-4-acetic acid (NSC64088). Cancer Res (1994) 54(4):870-872.
    • (1994) Cancer Res , vol.54 , Issue.4 , pp. 870-872
    • Ching, L.M.1    Joseph, W.R.2    Crosier, K.E.3    Baguley, B.C.4
  • 37
    • 0029063213 scopus 로고
    • Induction of tumour necrosis factor-α by single and repeated doses of the antitumor agent 5,6-dimethylxanthenone-4-acetic acid
    • note
    • Philpott M, Baguley BC, Ching LM: Induction of tumour necrosis factor-α by single and repeated doses of the antitumor agent 5,6-dimethylxanthenone-4-acetic acid. Cancer Chemother Pharmacol (1995) 36(2):143-148. Description of the mechanism of action of vascular targeting agent DMXAA.
    • (1995) Cancer Chemother Pharmacol , vol.36 , Issue.2 , pp. 143-148
    • Philpott, M.1    Baguley, B.C.2    Ching, L.M.3
  • 38
    • 0030951899 scopus 로고    scopus 로고
    • Combretastatin A-4, an agent that displays potent and selective toxicity toward tumor vasculature
    • Dark GG, Hill SA, Prise VE, Tozer GM, Pettit GR, Chaplin DJ: Combretastatin A-4, an agent that displays potent and selective toxicity toward tumor vasculature. Cancer Res (1997) 57(10):1829-1834.
    • (1997) Cancer Res , vol.57 , Issue.10 , pp. 1829-1834
    • Dark, G.G.1    Hill, S.A.2    Prise, V.E.3    Tozer, G.M.4    Pettit, G.R.5    Chaplin, D.J.6
  • 39
    • 0031742231 scopus 로고    scopus 로고
    • Targeting the tumor vasculature with combretastatin A-4 disodium phosphate: Effects on radiation therapy
    • Li L, Rojiani A, Siemann DW: Targeting the tumor vasculature with combretastatin A-4 disodium phosphate: Effects on radiation therapy. Int J Radiat Oncol Biol Phys (1998) 42(4):899-903.
    • (1998) Int J Radiat Oncol Biol Phys , vol.42 , Issue.4 , pp. 899-903
    • Li, L.1    Rojiani, A.2    Siemann, D.W.3
  • 41
    • 0031770618 scopus 로고    scopus 로고
    • The effect of combretastatin A-4 disodium phosphate n a C3H mouse mammary carcinoma and a variety of murine spontaneous tumours
    • Horsman MR, Ehrnrooth E, Ladekarl M, Overgaard J: The effect of combretastatin A-4 disodium phosphate n a C3H mouse mammary carcinoma and a variety of murine spontaneous tumours. Int J Radiat Oncol Biol Phys (1998) 42(4):895-898.
    • (1998) Int J Radiat Oncol Biol Phys , vol.42 , Issue.4 , pp. 895-898
    • Horsman, M.R.1    Ehrnrooth, E.2    Ladekarl, M.3    Overgaard, J.4
  • 42
    • 0032729686 scopus 로고    scopus 로고
    • Antitumor effects due to irreversible stoppage of tumor tissue blood flow: Evaluation of a novel combretastatin A-4 derivative, AC7700
    • Hori K, Saito S, Nihei Y, Suzuki M, Sato Y: Antitumor effects due to irreversible stoppage of tumor tissue blood flow: Evaluation of a novel combretastatin A-4 derivative, AC7700. Jpn J Cancer Res (1999) 90(9):1026-1038.
    • (1999) Jpn J Cancer Res , vol.90 , Issue.9 , pp. 1026-1038
    • Hori, K.1    Saito, S.2    Nihei, Y.3    Suzuki, M.4    Sato, Y.5
  • 43
    • 0034962379 scopus 로고    scopus 로고
    • Interaction between combretastatin A-4 disodium phosphate and radiation in murine tumours
    • Murata R, Siemann DW, Overgaard J, Horsman MR: Interaction between combretastatin A-4 disodium phosphate and radiation in murine tumours. Radiother Oncol (2001) 60(2):155-161.
    • (2001) Radiother Oncol , vol.60 , Issue.2 , pp. 155-161
    • Murata, R.1    Siemann, D.W.2    Overgaard, J.3    Horsman, M.R.4
  • 44
    • 0036569804 scopus 로고    scopus 로고
    • Enhancement of radiation therapy by the novel vascular targeting agent ZD6126
    • Siemann DW, Rojiani AM: Enhancement of radiation therapy by the novel vascular targeting agent ZD6126. Int J Radiat Oncol Biol Phys (2002) 53(1):164-171.
    • (2002) Int J Radiat Oncol Biol Phys , vol.53 , Issue.1 , pp. 164-171
    • Siemann, D.W.1    Rojiani, A.M.2
  • 45
    • 0032758736 scopus 로고    scopus 로고
    • In vivo and in vitro evaluation of combretastatin A-4 and its sodium phosphate prodrug
    • Grosios K, Holwell SE, McGown AT, Pettit GR, Bibby MC: In vivo and in vitro evaluation of combretastatin A-4 and its sodium phosphate prodrug. Br J Cancer (1999) 81(8):1318-1327.
    • (1999) Br J Cancer , vol.81 , Issue.8 , pp. 1318-1327
    • Grosios, K.1    Holwell, S.E.2    McGown, A.T.3    Pettit, G.R.4    Bibby, M.C.5
  • 46
    • 0035064594 scopus 로고    scopus 로고
    • Effects of combretastatin A4 phosphate on endothelial cell morphology in vitro and relationship to tumour vascular targeting activity in vivo
    • note
    • Galbraith SM, Chaplin DJ, Lee F, Stratford MR, Locke RJ, Vojnovic B, Tozer GM: Effects of combretastatin A4 phosphate on endothelial cell morphology in vitro and relationship to tumour vascular targeting activity in vivo. Anticancer Res (2001) 21(1A):93-102. Description of of mechanism of action of tubulin-binding based vascular targeting agents.
    • (2001) Anticancer Res , vol.21 , Issue.1 A , pp. 93-102
    • Galbraith, S.M.1    Chaplin, D.J.2    Lee, F.3    Stratford, M.R.4    Locke, R.J.5    Vojnovic, B.6    Tozer, G.M.7
  • 47
    • 0037085753 scopus 로고    scopus 로고
    • The tumor vascular targeting agent combrestatin A-4-phosphate induces reorganization of the actin cytoskeleton and early membrane blebbing in human endothelial cells
    • Kanthou C, Tozer GM: The tumor vascular targeting agent combrestatin A-4-phosphate induces reorganization of the actin cytoskeleton and early membrane blebbing in human endothelial cells. Blood (2002) 99(6):2060-2069.
    • (2002) Blood , vol.99 , Issue.6 , pp. 2060-2069
    • Kanthou, C.1    Tozer, G.M.2
  • 48
    • 0031775298 scopus 로고    scopus 로고
    • Enhancement of tumor radiation response by the antivascular agent 5,6-dimethylxanthenone-4-acetic acid
    • Wilson WR, Li AE, Cowan DSM, Siim BG: Enhancement of tumor radiation response by the antivascular agent 5,6-dimethylxanthenone-4-acetic acid. Int J Radiat Oncol Biol Phys (1998) 42(4):905-908.
    • (1998) Int J Radiat Oncol Biol Phys , vol.42 , Issue.4 , pp. 905-908
    • Wilson, W.R.1    Li, A.E.2    Cowan, D.S.M.3    Siim, B.G.4
  • 50
    • 0013454816 scopus 로고    scopus 로고
    • Targeting the tumor blood vessel network to enhance the efficacy of radiation therapy
    • in press.
    • Siemann DW, Shi W: Targeting the tumor blood vessel network to enhance the efficacy of radiation therapy. Semin Radiat Oncol (2002): in press.
    • (2002) Semin Radiat Oncol
    • Siemann, D.W.1    Shi, W.2
  • 52
    • 0036891440 scopus 로고    scopus 로고
    • Combination of vascular targeting agents with thermal or radiation therapy
    • in press.; note
    • Horsman MR, Murata R: Combination of vascular targeting agents with thermal or radiation therapy. Int J Radiat Oncol Biol Phys (2002): in press. Enhanced antitumor efficacy resulting from the combination of radiation or hyperthermia and vascular targeting agents.
    • (2002) Int J Radiat Oncol Biol Phys
    • Horsman, M.R.1    Murata, R.2
  • 53
    • 0034759198 scopus 로고    scopus 로고
    • Improved tumor response by combining radiation and the vascular damaging drug 5,6-dimethylxanthenone-4-acetic acid
    • Murata R, Siemann DW, Overgaard J, Horsman MR: Improved tumor response by combining radiation and the vascular damaging drug 5,6-dimethylxanthenone-4-acetic acid. Radiat Res (2001) 156(5 Pt 1):503-509.
    • (2001) Radiat Res , vol.156 , Issue.PART 1 , pp. 503-509
    • Murata, R.1    Siemann, D.W.2    Overgaard, J.3    Horsman, M.R.4
  • 54
    • 0036215178 scopus 로고    scopus 로고
    • Preclinical evaluations of therapies combining the vascular targeting agent combretastatin A-4 disodium phosphate and conventional anticancer therapies in the treatment of Kaposi's sarcoma
    • Li L, Rojiani AM, Siemann DW: Preclinical evaluations of therapies combining the vascular targeting agent combretastatin A-4 disodium phosphate and conventional anticancer therapies in the treatment of Kaposi's sarcoma. Acta Oncol (2002) 41(1):91-97.
    • (2002) Acta Oncol , vol.41 , Issue.1 , pp. 91-97
    • Li, L.1    Rojiani, A.M.2    Siemann, D.W.3
  • 55
    • 0036568457 scopus 로고    scopus 로고
    • Vascular targeting agents enhance chemotherapeutic agent activities in solid tumor therapy
    • note
    • Siemann DW, Mercer E, Lepler SE, Rojiani AM: Vascular targeting agents enhance chemotherapeutic agent activities in solid tumor therapy. Int J Cancer (2002) 99(1):1-6. Describes the therapeutic benefit achieved when combining DMXAA or CA4P with conventional anticancer drugs.
    • (2002) Int J Cancer , vol.99 , Issue.1 , pp. 1-6
    • Siemann, D.W.1    Mercer, E.2    Lepler, S.E.3    Rojiani, A.M.4
  • 56
    • 0036891109 scopus 로고    scopus 로고
    • Anti-tumor efficacy of conventional anticancer drugs in enhanced by the vascular targeting agent ZD6126
    • in press.
    • Siemann DW, Rojiani AM: Anti-tumor efficacy of conventional anticancer drugs in enhanced by the vascular targeting agent ZD6126. Int J Radiat Oncol Biol Phys (2002): in press.
    • (2002) Int J Radiat Oncol Biol Phys
    • Siemann, D.W.1    Rojiani, A.M.2


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