Differential effect of Bcl-xl over-expression on cell death of the monocytic leukemia cell line U937

Anticancer Research

Volumn 22, Issue 6 C, 2002, Pages 3911-3915

  Abdelhaleem, Mohamed ^a  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

Apoptosis; Bcl xl; Cell death; Etoposide; Proteasome inhibitors

Indexed keywords

CASPASE 3; CYTOCHROME C; DNA FRAGMENT; ETOPOSIDE; LACTACYSTIN; PROTEIN BCL XL;

ARTICLE; CELL DEATH; CELL PROTECTION; CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; LEUKEMIA CELL; PHENOTYPE; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN SECRETION;

ACETYLCYSTEINE; APOPTOSIS; BCL-X PROTEIN; CELL DEATH; ETOPOSIDE; HUMANS; NECROSIS; PROTO-ONCOGENE PROTEINS C-BCL-2; U937 CELLS;

EID: 0036875352     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Antonsson B and Martinou J-C: The Bcl-2 protein family. Exp Cell Res 256: 50-57, 2000.
2. Chao DT and Korsmeyer SJ: BCL-2 family: Regulators of cell death. Ann Rev Immunol 16: 395-419, 1998.
3. Simonian PL, Grillot DAM and Nunex G: Bcl-2 and Bcl-xl can differentially block chemotherapy-induced cell death. Blood 90: 1208-1216, 1997.
4. Decaudin D, Geley S, Hirsch T, Castedo M, Marchetti P, Macho A, Kofler R and Kroemer G: Bcl-2 and Bcl-xl antagonize the mitochondrial dysfunction preceding nuclear apoptosis induced by chemotherapeutic agents. Cancer Res 57: 62-67, 1997.
5. Vander Heiden MG, Chandel NS, Williamson EK, Schumacker PT and Thompson CB: Bcl-xl regulates the membrane potential and volume homeostasis of mitochondria. Cell 91: 627-37, 1997.
6. Reed JC, Jurgensmeier JM and Matsuyama S: Bcl-2 family proteins and mitochondria. Biochim Biophys Acta 1366: 127-37, 1998.
7. Andreeff M, jiang S, Zhang X, Konopleva M, Estrov Z, Snell VE, Xie Z, Okcu MF, Sanchez-Williams G, Dong J, Esty EH, Champlin RC, Kornblau SM, Reed JC and Zhao S: Expression of of bcl-2-related genes in normal and AML progenitors: changes induced by chemotherapy and retinoic acid. Leukemia 13: 1881-1892, 1999.
8. Masdehors P, Omura S, Merle-Beral H, Mentz F, Cosset JM, Dumont J, Magdelenat H and Delic J: Increased sensitivity of CLL-derived lymphocytes to apoptotic death activation by the proteasome-specific inhibitor lactacystin. Br J Haematol 105: 752-757, 1999.
9. Chandra J, Niemer I, Gilbreath J, Kliche KO, Andreeff M, Freireich EJ, Keating M and McConkey DJ: Proteasome inhibitors induce apoptosis in glucocorticoid-resistant chronic lymphocytic leukemic lymphocytes. Blood 92: 4220-4229, 1998.
10. Kharbanda S, Pandey P, Schofield L, Israels S, Roncinske R, Yoshida K, Bharti A, Yuan ZM, Saxena S, Weichselbaum R, Nalin C and Kufe D: Role for Bcl-xl as an inhibitor of cytosolic cytochrome C accumulation in DNA damage-induced apoptosis. Proc Natl Acad Sci U S A 94: 6939-6942, 1997.
11. Decaudin D, Geley S, Hirsch T, Castedo M, Marchetti P, Macho A, Kofler R and Kroemer G: Bcl-2 and Bcl-xl antagonize the mitochondrial dysfunction preceding nuclear apoptosis induced by chemotherapeutic agents. Cancer Res 57: 62-67, 1997.
12. Lammeli UK: Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227: 680-685, 1997.
13. Orlowski RZ: The role of the ubiquitin-proteasome pathway in apoptosis. Cell Death and Differentiation 6: 303-313, 1999.
14. Markins LM, Kottke T, Mesner PW, Basi GS, Sinha S, Frigon N, Tatar E, Tung JS, Brynat K., Takahashi A, Svingen PA, Madden BJ, McCormick DJ, Earnshaw WC and Kaufmann SH: Activation of multiple interluekin-1 b converting enzyme homologues in cytosol and nuclei of HL-60 cells during etoposide-induced apoptosis. J Biol Chem 272: 7421, 1997.
15. Xiang J, Chao DT and Korsmeyer SJ: Bax-induced cell death may not require interleukin 1 b-converting enzyme-like proteases. Proc Natl Acad Sci USA 93: 14559-14563, 1996.
16. Lee JU, Hosotani R, Wada M, Doi R, Kosiba T, Fujimoto K, Miyamoto Y, Mori C, Nakamura N, Shiota K and Imamura M: Mechanism of apoptosis induced by cisplatin and VP-16 in PANC-1 cells. Anticancer Res. 17: 3445-3450, 1997.
17. Abdelhaleem M: A role for the subcellular localization of bax in differentiation-induced resistance to apoptosis in HL-60 cells. Anticancer Research 22: 177-182, 2002.
18. Zanke BW, Lee C, Arab S and Tannock IF: Death of tumor cells after intracellular acidification is dependent on stress-activated protein kinases (SAPK/JNK) pathway activation and cannot be inhibited by Bcl-2 expression or interleukin 1beta-converting enzyme inhibition. Cancer Res 58: 2801-2808, 1998.
19. Furlong IJ, Ascaso R, Lopez Rivas A and Collins MK: Intracellular acidification induces apoptosis by stimulating ICE-like protease activity. J Cell Sci 110: 653-661, 1997.
20. Barry MA, Reynolds JE and Eastman A: Etoposide-induced apoptosis in human HL-60 cells is associated with intracellular acidification Cancer Research 53: 2349-2357, 1993.
21. Benson RS, Dive C and Watson AJ: Cytoplasmic acidification is not an effector mechanism of VP16 or DEX-induced apoptosis in CEM T-leukaemia cells. J Cell Sci 112: 1755-1760, 1999.
22. Chi S, Kitanaka C, Noguchi K, Mochizuki T, Nagashima Y, Shirouzu M, Fujita H, Yoshida M, Chen W, Asai A, Himeno M, Yokiyama S and Kuchino Y: Oncogenic Ras triggers cell suicide through the activation of a caspase-independent cell death program in human cancer cells. Oncogene 18: 2281-2290, 1999.
23. Voges D, Zwickl P and Baumeister W: The 26S proteasome: a molecular machine designed for controlled proteolysis. Annu Rev Biochem 68: 1015-1068, 1999.
24. Imajoh-Ohmi S, Kawaguchi T, Sugiyama S, Tanaka K, Omura S and Kikuchi H: Lactacystin, a specific inhibitor of the proteasome, induces apoptosis in human monoblast U937 cells. Biochem Biophys Res Commun 217: 1070-1077, 1995.
25. Grimm LM, Goldberg AL, Poirier GG, Schwartz LM and Osborne BA: Proteasomes play an essential role in thymocyte apoptosis. EMBO J 15: 3835-3844, 1996.
26. Herrmann JL, Briones F Jr, Brisbay S, Logothetis CJ and McDonnell TJ: Prostate carcinoma cell death resulting from inhibition of proteasome activity is independent of functional Bcl-2 and p53. Oncogene 17: 2889-2899, 1998.
27. Kitagawa H, Tani E, Ikemoto H, Ozaki I, Nakano A and Omura S: Proteasome inhibitors induce mitochondria-independent apoptosis in human glioma cells. FEBS Lett 443: 181-186, 1999.