Substrate specificity and inhibitor studies of a membrane-bound ganglioside sialidase isolated from human brain tissue

Biological Chemistry

Volumn 383, Issue 11, 2002, Pages 1735-1742

  Oehler, Christian ^a   Kopitz, Jürgen ^a   Cantz, Michael ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Cell surface; Glycolipid; Glycosamino glycan; Neuraminidase; Plasma membrane; Sialic acid

Indexed keywords

4 NITROPHENYLOXAMIC ACID; CHONDROITIN 4 SULFATE; DERMATAN SULFATE; DEXTRAN SULFATE; GANGLIOSIDE; GLYCOSAMINOGLYCAN; HEPARAN SULFATE; HEPARIN; N ACETYL 2,3 DIDEHYDRO 2 DEOXYNEURAMINIC ACID; SIALIC ACID; SIALIDASE; SIALIDASE INHIBITOR; SURAMIN; UNCLASSIFIED DRUG; ZANAMIVIR;

ACETYLATION; CELL ADHESION; CELL DIFFERENTIATION; CELL GROWTH; CELL SURFACE; CONTROLLED STUDY; ENZYME DEGRADATION; ENZYME INACTIVATION; ENZYME INHIBITION; ENZYME ISOLATION; ENZYME PURIFICATION; ENZYME SPECIFICITY; ENZYME STABILITY; EXTRACELLULAR MATRIX; HUMAN; HUMAN TISSUE; IC 50; PRIORITY JOURNAL; REVIEW; SOLUBILITY;

ANTIBODY SPECIFICITY; BLOTTING, WESTERN; BRAIN; CELL MEMBRANE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME INHIBITORS; EPITOPES; GANGLIOSIDES; GLYCOSAMINOGLYCANS; HEPARIN; HUMANS; METALS, HEAVY; N-ACETYLNEURAMINIC ACID; NEURAMINIDASE; SUBSTRATE SPECIFICITY; SULFATES;

BACTERIA (MICROORGANISMS); INFLUENZA VIRUS;

EID: 0036869102     PISSN: 14316730     EISSN: None     Source Type: Journal    
DOI: 10.1515/BC.2002.194     Document Type: Review

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