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Volumn 15, Issue 9, 2002, Pages 586-590

Glial cells as a target for the development of new therapies for treating Parkinson's disease

Author keywords

[No Author keywords available]

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; PROTEIN S100B;

EID: 0036868976     PISSN: 02140934     EISSN: None     Source Type: Journal    
DOI: 10.1358/dnp.2002.15.9.740227     Document Type: Review
Times cited : (5)

References (41)
  • 2
    • 0025893945 scopus 로고
    • Parkinson's disease: Pathophysiology
    • Agid, Y. Parkinson's disease: Pathophysiology. Lancet 1991, 337: 1321-4.
    • (1991) Lancet , vol.337 , pp. 1321-1324
    • Agid, Y.1
  • 3
    • 0021280826 scopus 로고
    • Dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice
    • Heikkila, R.E., Hess, A. and Duvoisin, R.C. Dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice. Science 1984, 224: 1451-3.
    • (1984) Science , vol.224 , pp. 1451-1453
    • Heikkila, R.E.1    Hess, A.2    Duvoisin, R.C.3
  • 4
    • 0025330367 scopus 로고
    • Evaluation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated C57 black mouse model of parkinsonism
    • Arai, N., Misugi, K., Goshima, Y. and Misu, Y. Evaluation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated C57 black mouse model of parkinsonism. Brain Res 1990, 515: 57-63.
    • (1990) Brain Res , vol.515 , pp. 57-63
    • Arai, N.1    Misugi, K.2    Goshima, Y.3    Misu, Y.4
  • 5
    • 0028302235 scopus 로고
    • Differences in nigral neuron number and sensitivity to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in C57/bl and CD-1 mice
    • Muthane, U., Ramsay, K.A., Jiang, H., Lewis, V.J., Donaldson, D., Fernando, S., Ferreira, M. and Przedborski, S. Differences in nigral neuron number and sensitivity to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in C57/bl and CD-1 mice. Exp Neurol 1994, 126: 195-204.
    • (1994) Exp Neurol , vol.126 , pp. 195-204
    • Muthane, U.1    Ramsay, K.A.2    Jiang, H.3    Lewis, V.J.4    Donaldson, D.5    Fernando, S.6    Ferreira, M.7    Przedborski, S.8
  • 7
    • 0036522967 scopus 로고    scopus 로고
    • Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease
    • Wu, D.C., Jackson-Lewis, V., Vila, M., Tieu, K., Teismann, P., Vadseth, C., Choi, D.K., Ischiropoulos, H. and Przedborski, S. Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease. J Neurosci 2002, 22: 1763-71.
    • (2002) J Neurosci , vol.22 , pp. 1763-1771
    • Wu, D.C.1    Jackson-Lewis, V.2    Vila, M.3    Tieu, K.4    Teismann, P.5    Vadseth, C.6    Choi, D.K.7    Ischiropoulos, H.8    Przedborski, S.9
  • 8
    • 0021276089 scopus 로고
    • Metabolism of the neurotoxic tertiary amine, MPTP, by brain monoamine oxidase
    • Chiba, K., Trevor, A. and Castagnoli, N., Jr. Metabolism of the neurotoxic tertiary amine, MPTP, by brain monoamine oxidase. Biochem Biophys Res Commun 1984, 120: 574-8.
    • (1984) Biochem Biophys Res Commun , vol.120 , pp. 574-578
    • Chiba, K.1    Trevor, A.2    Castagnoli N., Jr.3
  • 9
    • 0027454020 scopus 로고
    • Dopaminergic transporter expression confers cytotoxicity to low doses of the parkinsonism-inducing neurotoxin 1-methyl-4-phenylpyridinium
    • Pifl, C., Giros, B. and Caron, M.G. Dopaminergic transporter expression confers cytotoxicity to low doses of the parkinsonism-inducing neurotoxin 1-methyl-4-phenylpyridinium. J Neurosci 1993, 13: 4246-53.
    • (1993) J Neurosci , vol.13 , pp. 4246-4253
    • Pifl, C.1    Giros, B.2    Caron, M.G.3
  • 10
    • 0022503139 scopus 로고
    • Studies on the neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: Inhibition of NAD-linked substrate oxidation by its metabolite, 1-methyl-4-phenylpyridinium
    • Vyas, I., Heikkila, R.E. and Nicklas, W.J. Studies on the neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: Inhibition of NAD-linked substrate oxidation by its metabolite, 1-methyl-4-phenylpyridinium. J Neurochem 1986, 46: 1501-7.
    • (1986) J Neurochem , vol.46 , pp. 1501-1507
    • Vyas, I.1    Heikkila, R.E.2    Nicklas, W.J.3
  • 11
    • 0025329856 scopus 로고
    • Effects of 1-methyl-4-phenylpyridium ion on ATP levels of mouse brain synaptosomes
    • Scotcher, K.P., Irwin, I., DeLanney, L.E., Langston, J.W. and Di Monte, D. Effects of 1-methyl-4-phenylpyridium ion on ATP levels of mouse brain synaptosomes. J Neurochem 1990, 54: 1295-301.
    • (1990) J Neurochem , vol.54 , pp. 1295-1301
    • Scotcher, K.P.1    Irwin, I.2    DeLanney, L.E.3    Langston, J.W.4    Di Monte, D.5
  • 12
    • 0027965971 scopus 로고
    • Characterization of the inhibitory mechanism of 1-methyl-4-phenylpyridinium and 4-phenylpyridine analogs in inner membrane preparations
    • Gluck, M.R., Krueger, M.J., Ramsay, S.S., Sablin, S.O., Singer, T.P. and Nicklas, W.J. Characterization of the inhibitory mechanism of 1-methyl-4-phenylpyridinium and 4-phenylpyridine analogs in inner membrane preparations. J Biol Chem 1994, 269: 3167-74.
    • (1994) J Biol Chem , vol.269 , pp. 3167-3174
    • Gluck, M.R.1    Krueger, M.J.2    Ramsay, S.S.3    Sablin, S.O.4    Singer, T.P.5    Nicklas, W.J.6
  • 13
    • 0023001744 scopus 로고
    • Energy-dependent uptake of N-methyl-4-phenylpyridinium, the neurotoxic metabolite of 1-methyl4-phenyl-1,2,3,6-tetrahydropyridine, by mitochondria
    • Ramsay, R.R. and Singer, T.P. Energy-dependent uptake of N-methyl-4-phenylpyridinium, the neurotoxic metabolite of 1-methyl4-phenyl-1,2,3,6-tetrahydropyridine, by mitochondria. J Biol Chem 1986, 261: 7585-7.
    • (1986) J Biol Chem , vol.261 , pp. 7585-7587
    • Ramsay, R.R.1    Singer, T.P.2
  • 14
    • 0028796770 scopus 로고
    • Inhibition of neuronal nitric oxide synthase by 7-nitroindazole protects against MPTP-induced neurotoxicity in mice
    • Schulz, J.B., Matthews, R.T., Muqit, M.M.K., Browne, S.E. and Beal, M.F. Inhibition of neuronal nitric oxide synthase by 7-nitroindazole protects against MPTP-induced neurotoxicity in mice. J Neurochem 1995, 64: 936-9.
    • (1995) J Neurochem , vol.64 , pp. 936-939
    • Schulz, J.B.1    Matthews, R.T.2    Muqit, M.M.K.3    Browne, S.E.4    Beal, M.F.5
  • 15
    • 0029984860 scopus 로고    scopus 로고
    • Role of neuronal nitric oxide in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity
    • Przedborski, S., Lewis, W.J., Yokoyama, R., Shibata, T., Dawson, V.L. and Dawson, T.M. Role of neuronal nitric oxide in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity. Proc Natl Acad Sci USA 1996, 93: 4565-71.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 4565-4571
    • Przedborski, S.1    Lewis, W.J.2    Yokoyama, R.3    Shibata, T.4    Dawson, V.L.5    Dawson, T.M.6
  • 16
    • 0031893563 scopus 로고    scopus 로고
    • Glial calcium: Homeostasis and signaling function
    • Verkhratsky, A., Orkand, R.K. and Kettenmann, H. Glial calcium: Homeostasis and signaling function. Physiol Rev 1998, 78: 99-141.
    • (1998) Physiol Rev , vol.78 , pp. 99-141
    • Verkhratsky, A.1    Orkand, R.K.2    Kettenmann, H.3
  • 17
    • 0026335130 scopus 로고
    • New roles of glia
    • Barres, B.A. New roles of glia. J Neurosci 1991, 11: 3685-94.
    • (1991) J Neurosci , vol.11 , pp. 3685-3694
    • Barres, B.A.1
  • 18
    • 0031105802 scopus 로고    scopus 로고
    • Astrocytic neurotransmitter receptors in situ and in vivo
    • Porter, J.T. and McCarthy, K.D. Astrocytic neurotransmitter receptors in situ and in vivo. Prog Neurobiol 1997, 51: 439-55.
    • (1997) Prog Neurobiol , vol.51 , pp. 439-455
    • Porter, J.T.1    McCarthy, K.D.2
  • 19
  • 20
    • 0030221778 scopus 로고    scopus 로고
    • Signalling from neurons to glial cells in invertebrates
    • Coles, J.A. and Abbott, N.J. Signalling from neurons to glial cells in invertebrates. Trends Neurosci 1996, 19: 358-62.
    • (1996) Trends Neurosci , vol.19 , pp. 358-362
    • Coles, J.A.1    Abbott, N.J.2
  • 21
    • 0029927343 scopus 로고    scopus 로고
    • Metabolic coupling between glia and neurons
    • Tsacopoulos, M. and Magistretti, P.J. Metabolic coupling between glia and neurons. J Neurosci 1996, 16: 877-85.
    • (1996) J Neurosci , vol.16 , pp. 877-885
    • Tsacopoulos, M.1    Magistretti, P.J.2
  • 22
    • 0030201340 scopus 로고    scopus 로고
    • The Muller cell: A functional element of the retina
    • Newman, E. and Reichenbach, A. The Muller cell: A functional element of the retina. Trends Neurosci 1996, 19: 307-12.
    • (1996) Trends Neurosci , vol.19 , pp. 307-312
    • Newman, E.1    Reichenbach, A.2
  • 23
    • 0028349645 scopus 로고
    • Glial contributions to excitatory neurotransmitter in cultured hippocampal cells
    • Mennerick, S. and Zorumski, C.F. Glial contributions to excitatory neurotransmitter in cultured hippocampal cells. Nature 1994, 368: 59-62.
    • (1994) Nature , vol.368 , pp. 59-62
    • Mennerick, S.1    Zorumski, C.F.2
  • 24
    • 0030773837 scopus 로고    scopus 로고
    • Synaptic efficacy enhanced by glial cells in vitro
    • Pfrieger, F.W. and Barres, B.A. Synaptic efficacy enhanced by glial cells in vitro. Science 1997, 277: 1684-7.
    • (1997) Science , vol.277 , pp. 1684-1687
    • Pfrieger, F.W.1    Barres, B.A.2
  • 26
    • 0001412747 scopus 로고    scopus 로고
    • Astrocytes provide cysteine to neurons by releasing glutathione
    • Wang, X.F. and Cynader, M.S. Astrocytes provide cysteine to neurons by releasing glutathione. J Neurochem 2000, 74: 1434-42.
    • (2000) J Neurochem , vol.74 , pp. 1434-1442
    • Wang, X.F.1    Cynader, M.S.2
  • 27
    • 0033555806 scopus 로고    scopus 로고
    • Synthesis of the antioxidant glutathione in neurons: Supply by astrocytes of CysGly as precursor for neuronal glutathione
    • Dringen, R., Pfeiffer, B. and Hamprecht, B. Synthesis of the antioxidant glutathione in neurons: Supply by astrocytes of CysGly as precursor for neuronal glutathione. J Neurochem 1999, 19: 562-9.
    • (1999) J Neurochem , vol.19 , pp. 562-569
    • Dringen, R.1    Pfeiffer, B.2    Hamprecht, B.3
  • 28
    • 0024990290 scopus 로고
    • 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced damage of striatal dopaminergic fibers attenuates subsequent astrocytes response to MPTP
    • O'Callaghan, J.P., Miller, D.B. and Reinhard, J.F., Jr. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced damage of striatal dopaminergic fibers attenuates subsequent astrocytes response to MPTP. Neurosci Lett 1990, 117: 228-33.
    • (1990) Neurosci Lett , vol.117 , pp. 228-233
    • O'Callaghan, J.P.1    Miller, D.B.2    Reinhard J.F., Jr.3
  • 29
    • 0027258617 scopus 로고
    • The histochemical demonstration of MPTP oxidation in postmortem human striatum
    • Nakamura, S., Akiguchi, I. and Kimura, J. The histochemical demonstration of MPTP oxidation in postmortem human striatum. Neurosci Lett 1993, 154: 61-4.
    • (1993) Neurosci Lett , vol.154 , pp. 61-64
    • Nakamura, S.1    Akiguchi, I.2    Kimura, J.3
  • 31
    • 0033541623 scopus 로고    scopus 로고
    • Differential vulnerability of dopamine receptors in the mouse brain treated with MPTP
    • Tanji, H., Araki, T., Nagasawa, H. and Itoyama, Y. Differential vulnerability of dopamine receptors in the mouse brain treated with MPTP Brain Res 1999, 824: 224-31.
    • (1999) Brain Res , vol.824 , pp. 224-231
    • Tanji, H.1    Araki, T.2    Nagasawa, H.3    Itoyama, Y.4
  • 32
    • 0028928357 scopus 로고
    • The S100 protein family: History, function, and expression
    • Zimmer, D.B., Cornwall, E.H., Landar, A. and Song, W. The S100 protein family: History, function, and expression. Brain Res Bull 1995, 37: 417-29.
    • (1995) Brain Res Bull , vol.37 , pp. 417-429
    • Zimmer, D.B.1    Cornwall, E.H.2    Landar, A.3    Song, W.4
  • 33
    • 0011902120 scopus 로고
    • Production and characterization of monoclonal antibodies with specificity for the S100 beta polypeptide of brain S100 fractions
    • Van Eldik, I.J., Ehrenfried, B. and Jensen, R.A. Production and characterization of monoclonal antibodies with specificity for the S100 beta polypeptide of brain S100 fractions. Proc Natl Acad Sci USA 1984, 81: 6034-8.
    • (1984) Proc Natl Acad Sci USA , vol.81 , pp. 6034-6038
    • Van Eldik, I.J.1    Ehrenfried, B.2    Jensen, R.A.3
  • 35
    • 0001360461 scopus 로고
    • Brain interteukin-1 and S-100beta immunoreactivity elevated in Down's syndrome and Alzheimer's disease
    • Griffin, W.S.T., Stanley, L.C., Ling, C., White, L.M., White, C.L. and Araoz, C. Brain interteukin-1 and S-100beta immunoreactivity elevated in Down's syndrome and Alzheimer's disease. Proc Natl Acad Sci USA 1989, 86: 7611-5.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 7611-7615
    • Griffin, W.S.T.1    Stanley, L.C.2    Ling, C.3    White, L.M.4    White, C.L.5    Araoz, C.6
  • 36
    • 0030757323 scopus 로고    scopus 로고
    • Neuritic plaque evolution in Alzheimer's disease is accompanied by transition of activated microglia from primed to enlarged to phagocytic forms
    • Sheng, J.G., Mark, R.E. and Griffin, W.S. Neuritic plaque evolution in Alzheimer's disease is accompanied by transition of activated microglia from primed to enlarged to phagocytic forms. Acta Neuropathol 1997, 94: 1-5.
    • (1997) Acta Neuropathol , vol.94 , pp. 1-5
    • Sheng, J.G.1    Mark, R.E.2    Griffin, W.S.3
  • 37
    • 0033547879 scopus 로고    scopus 로고
    • S-100beta protein is upregulated in astrocytes and motor neurons in the spinal cord of patients with amyotrophic lateral sclerosis
    • Migheli, A., Cordera, S., Bendotti, C., Atzori, C., Piva, R. and Schiffer, D. S-100beta protein is upregulated in astrocytes and motor neurons in the spinal cord of patients with amyotrophic lateral sclerosis. Neurosci Lett 1999, 261: 25-8.
    • (1999) Neurosci Lett , vol.261 , pp. 25-28
    • Migheli, A.1    Cordera, S.2    Bendotti, C.3    Atzori, C.4    Piva, R.5    Schiffer, D.6
  • 39
    • 0031446195 scopus 로고    scopus 로고
    • Transgenic mice overexpressing the neurotrophic factor S-100 beta show neuronal cytoskeletal and behavioral signs of altered aging processes: Implications for Alzheimer's disease and Down's syndrome
    • Whitaker-Azmitia, P.M., Wingate, M., Borella, A., Gerlai, R., Roder, J. and Azmitia, E.C. Transgenic mice overexpressing the neurotrophic factor S-100 beta show neuronal cytoskeletal and behavioral signs of altered aging processes: Implications for Alzheimer's disease and Down's syndrome. Brain Res 1997, 776: 51-60.
    • (1997) Brain Res , vol.776 , pp. 51-60
    • Whitaker-Azmitia, P.M.1    Wingate, M.2    Borella, A.3    Gerlai, R.4    Roder, J.5    Azmitia, E.C.6
  • 40
    • 0036259904 scopus 로고    scopus 로고
    • Astrocytic activation and delayed infarct expansion after permanent focal ischemia in rats. Part I: Enhanced astrocytic synthesis of s-100beta in the periinfarct area precedes delayed infarct expansion
    • Matsui, T., Mori, T., Tateishi, N., Kagamiishi, Y., Satoh, S., Katsube, N., Morikawa, E., Morimoto, T., Ikuta, F. and Asano, T. Astrocytic activation and delayed infarct expansion after permanent focal ischemia in rats. Part I: Enhanced astrocytic synthesis of s-100beta in the periinfarct area precedes delayed infarct expansion. J Cereb Blood Flow Metab 2002, 22: 711-22.
    • (2002) J Cereb Blood Flow Metab , vol.22 , pp. 711-722
    • Matsui, T.1    Mori, T.2    Tateishi, N.3    Kagamiishi, Y.4    Satoh, S.5    Katsube, N.6    Morikawa, E.7    Morimoto, T.8    Ikuta, F.9    Asano, T.10
  • 41
    • 0036263210 scopus 로고    scopus 로고
    • Astrocytic activation and delayed infarct expansion after permanent focal ischemia in rats. Part II: Suppression of astrocytic activation by a novel agent (R)-(-)-2-propyloctanoic acid (ONO-2506) leads to mitigation of delayed infarct expansion and early improvement of neurologic deficits
    • Tateishi, N., Mori, T., Kagamiishi, Y., Satoh, S., Katsube, N., Morikawa, E., Morimoto, T., Matsui, T. and Asano T. Astrocytic activation and delayed infarct expansion after permanent focal ischemia in rats. Part II: Suppression of astrocytic activation by a novel agent (R)-(-)-2-propyloctanoic acid (ONO-2506) leads to mitigation of delayed infarct expansion and early improvement of neurologic deficits. J Cereb Blood Flow Metab 2002, 22: 723-34.
    • (2002) J Cereb Blood Flow Metab , vol.22 , pp. 723-734
    • Tateishi, N.1    Mori, T.2    Kagamiishi, Y.3    Satoh, S.4    Katsube, N.5    Morikawa, E.6    Morimoto, T.7    Matsui, T.8    Asano, T.9


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