The yeast ubiquitin protease, Ubp3p, promotes protein stability

Genetics

Volumn 162, Issue 3, 2002, Pages 1079-1089

  Brew, Christine T ^a,b   Huffaker, Tim C ^a  

^a Department of Obstetrics Gynecology   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTEINE PROTEINASE; MICROTUBULE ASSOCIATED PROTEIN; PROTEIN STULP; PROTEIN UBP3P; UBIQUITIN PROTEASE; UNCLASSIFIED DRUG; BENOMYL; MYOSIN HEAVY CHAIN; PROTEIN; PROTEINASE; SACCHAROMYCES CEREVISIAE PROTEIN; STU1 PROTEIN, S CEREVISIAE; STU2 PROTEIN, S CEREVISIAE; UBIQUITIN; UBP3 PROTEIN, S CEREVISIAE;

ALLELE; ARTICLE; GENE INTERACTION; GENE MUTATION; GIM1 GIM5 GENE; KEM1 GENE; MITOSIS SPINDLE; NONHUMAN; PRIORITY JOURNAL; PROTEIN STABILITY; TEMPERATURE SENSITIVITY; UBP3 GENE; YEAST; CELL CYCLE; GENETICS; HEAT; LETHAL GENE; METABOLISM; PHYSIOLOGY; PROTEIN FOLDING; SACCHAROMYCES CEREVISIAE;

BENOMYL; CELL CYCLE; ENDOPEPTIDASES; GENES, LETHAL; HEAT; MICROTUBULE-ASSOCIATED PROTEINS; MYOSIN HEAVY CHAINS; PROTEIN FOLDING; PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; UBIQUITIN;

EID: 0036862055     PISSN: 00166731     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (57)

1. Akhmanova, A., C. C. Hoogenraad, K. Drabek, T. Stepanova, B. Dortland et al., 2001 Clasps are CLIP-115 and -170 associating proteins involved in the regional regulation of microtubule dynamics in motile fibroblasts. Cell 104: 923-935.
2. Amerik, A. Y., S. Swaminathan, B. A. Krantz, K. D. Wilkinson and M. Hochstrasser, 1997 In vivo disassembly of free polyubiquitin chains by yeast Ubp14 modulates rates of protein degradation by the proteasome. EMBO J. 16: 4826-4838.
3. Amerik, A. Y., S. J. Li and M. Hochstrasser, 2000 Analysis of the deubiquitinating enzymes of the yeast Saccharomyces cerevisiae. Biol. Chem. 381: 981-992.
4. Baker, R. T., J. W. Tobias and A. Varshavsky, 1992 Ubiquitin-specific proteases of Saccharomyces cerevisiae. Cloning of UBP2 and UBP3, and functional analysis of the UBP gene family. J. Biol. Chem. 267: 23364-23375.
5. Baudin, A., O. Ozier-Kalogeropoulos, A. Denouel, F. Lacroute and C. Cullin, 1993 A simple and efficient method for direct gene deletion in Saccharomyces cerevisiae. Nucleic Acids Res. 21: 3329-3330.
6. Baxter, B. K., and E. A. Craig, 1998 Isolation of Ubp3, encoding a de-ubiquitinating enzyme, as a multicopy suppressor of a heat-shock mutant strain of S. cerevisiae. Curr. Genet. 33: 412-419.
7. Bender, A., and J. R. Pringle, 1991 Use of a screen for synthetic lethal and multicopy suppressee mutants to identify two new genes involved in morphogenesis in Saccharomyces cerevisiae. Mol. Cell. Biol. 11: 1295-1305.
8. Bradford, M. M., 1976 A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72: 248-254.
9. Caponigro, G., and R. Parker, 1996 Mechanisms and control of mRNA turnover in Saccharomyces cerevisiae. Microbiol. Rev. 60: 233-249.
10. Chung, C. H., and S. H. Baek, 1999 Deubiquitinating enzymes: Their diversity and emerging roles. Biochem. Biophys. Res. Commun. 266: 633-640.
11. Ciosk, R., W. Zachariae, C. Michaelis, A. Shevchenko, M. Mann et al., 1998 An ESP1/PDS1 complex regulates loss of sister chromatid cohesion at the metaphase to anaphase transition in yeast. Cell 93: 1067-1076.
12. Cohen-Fix, O., J. M. Peters, M. W. Kirschner and D. Koshland, 1996 Anaphase initiation in Saccharomyces cerevisiae is controlled by the APC-dependent degradation of the anaphase inhibitor Pds1p. Genes Dev. 10: 3081-3093.
13. Cowan, N. J., 1998 Mammalian cytosolic chaperonin. Methods Enzymol. 290: 230-241.
14. D'Andrea, A., and D. Pellman, 1998 Deubiquitinating enzymes: A new class of biological regulators. Crit. Rev. Biochem. Mol. Biol. 33: 337-352.
15. Finley, D., 1992 The yeast ubiquitin system, pp. 539-581 in The Molecular and Cellular Biology of the Yeast Saccharomyces. II. Gene Expression. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
16. Geissler, S., K. Siegers and E. Schiebel, 1998 A novel protein complex promoting formation of functional alpha- and gamma-tubulin. EMBO J. 17: 952-966.
17. Glickman, M. H., 2000 Getting in and out of the proteasome. Semin. Cell Dev. Biol. 11: 149-158.
18. Govindan, B., R. Bowser and P. Novick, 1995 The role of Myo2, a yeast class V myosin, in vesicular transport. J. Cell Biol. 128: 1055-1068.
19. Guthrie, C., and G. R. Fink, 1991 Guide to Yeast Genetics and Molecular Biology, Vol. 194. Academic Press, San Diego.
20. Hansen, W. J., N. J. Cowan and W. J. Welch, 1999 Prefoldin-nascent chain complexes in the folding of cytoskeletal proteins. J. Cell Biol. 145: 265-277.
21. Henry, Y., H. Wood, J. P. Morrissey, E. Petfalski, S. Kearsey et al., 1994 The 5′ end of yeast 5.8S rRNA is generated by exonucleases from an upstream cleavage site. EMBOJ. 13: 2452- 2463.
22. Hershko, A., and A. Ciechanover, 1998 The ubiquitin system. Annu. Rev. Biochem. 67: 425-479.
23. Hochstrasser, M., 1996 Ubiquitin-dependent protein degradation. Annu. Rev. Genet. 30: 405-439.
24. Hsu, C. L., and A. Stevens, 1993 Yeast cells lacking 5′-3′ exoribonuclease 1 contain mRNA species that are poly(A) deficient and partially lack the 5′ cap structure. Mol. Cell. Biol. 13: 4826-4835.
25. Huang, Y., R. T. Baker and J. A. Fischer-Vize, 1995 Control of cell fate by a deubiquitinating enzyme encoded by the fat facets gene. Science 270: 1828-1831.
26. Hutter, K. J., and H. E. Eipel, 1978 Flow cytometric determinations of cellular substances in algae, bacteria, moulds and yeasts. Antonie Leeuwenhoek 44: 269-282.
27. Interthal, H., C. Bellocq, J. Bahler, V. I. Bashkirov, S. Edelstein et al., 1995 A role of Sep1 (= Kem1, Xrn1) as a microtubule-associated protein in Saccharomyces cerevisiae. EMBO J. 14: 1057-1066.
28. Johnson, A. W., 1997 Rat1p and Xrn1p are functionally interchangeable exoribonucleases that are restricted to and required in the nucleus and cytoplasm, respectively. Mol. Cell. Biol. 17: 6122-6130.
29. Jones, E. W., 1991 Three proteolytic systems in the yeast Saccharomyces cerevisiae. J. Biol. Chem. 266: 7963-7966.
30. Juang, Y. L., J. Huang, J. M. Peters, M. E. McLaughlin, C. Y. Tai et al., 1997 APC-mediated proteolysis of Asel and the morphogenesis of the mitotic spindle. Science 275: 1311-1314.
31. Kim, J., P. O. Ljungdahl and G. R. Fink, 1990 Kem mutations affect nuclear fusion in Saccharomyces cerevisiae. Genetics 126: 799-812.
32. Kosco, K. A., 2002 Characterization of Stu2: Its Role in Regulating Microtubule Dynamics and Its Interaction with Bik1 and Bim1 in Saccharomyces Cerevisiae. Ph.D. Thesis, Cornell University, Ithaca, NY.
33. Kosco, K. A., C. G. Pearson, P. S. Maddox, P. J. Wang, I. R. Adams et al., 2001 Control of microtubule dynamics by stu2p is essential for spindle orientation and metaphase chromosome alignment in yeast. Mol. Biol. Cell 12: 2870-2880.
34. Larimer, F. W., C. L. Hsu, M. K. Maupin and A. Stevens, 1992 Characterization of the XRN1 gene encoding a 5′→3′ exoribonuclease: Sequence data and analysis of disparate protein and mRNA levels of gene-disrupted yeast cells. Gene 120: 51-57.
35. Lemos, C. L., P. Sampaio, H. Maiato, M. Costa, L. V. Omel'yanchuk et al., 2000 Mast, a conserved microtubule-associated protein required for bipolar mitotic spindle organization. EMBO J. 19: 3668-3682.
36. Lim, H. H., P. Y. Goh and U. Surana, 1998 Cdc20 is essential for the cyclosome-mediated proteolysis of both Pds1 and Clb2 during M phase in budding yeast. Curr. Biol. 8: 231-234.
37. Liu, C. C., H. I. Miller, W. J. Kohr and J. I. Silber, 1989 Purification of a ubiquitin protein peptidase from yeast with efficient in vitro assays. J. Biol. Chem. 264: 20331-20338.
38. Moazed, D., and D. Johnson, 1996 A deubiquitinating enzyme interacts with SIR4 and regulates silencing in S. ceresisiae. Cell 86: 667-677.
39. Muhlrad, D., C. J. Decker and R. Parker, 1994 Deadenylation of the unstable mRNA encoded by the yeast MFA2 gene leads to decapping followed by 5′→-3′ digestion of the transcript. Genes Dev. 8: 855-866.
40. Ozkaynak, E., D. Finley, M. J. Solomon and A. Varshavsky, 1987 The yeast ubiquitin genes: A family of natural gene fusions. EMBO J. 6: 1429-1439.
41. Page, A. M., K. Davis, C. Molineux, R. D. Kolodner and A. W. Johnson, 1998 Mutational analysis of exoribonuclease I from Saccharomyces cerevisiae. Nucleic Acids Res. 26: 3707-3716.
42. Papa, F. R., and M. Hochstrasser, 1993 The yeast Doa4 gene encodes a deubiquitinating enzyme related to a product of the human tre-2 oncogene. Nature 366: 313-319.
43. Pasqualone, D., and T. C. Huffaker, 1994 Stu1, a suppressor of a β-tubulin mutation, encodes a novel and essential component of the yeast mitotic spindle. J. Cell Biol. 127: 1973-1984.
44. Petfalski, E., T. Dandekar, Y. Henry and D. Tollervey, 1998 Processing of the precursors to small nucleolar RNAs and rRNAs requires common components. Mol. Cell. Biol. 18: 1181-1189.
45. Pickart, C. M., and I. A. Rose, 1985 Ubiquitin carboxyl-terminal hydrolase acts on ubiquitin carboxyl-terminal amides. J. Biol. Chem. 260: 7903-7910.
46. Rose, I. A., and J. V. Warms, 1983 An enzyme with ubiquitin carboxyterminal esterase activity from reticulocytes. Biochemistry 22: 4234-4237.
47. Schott, D., 2000 The Carboxyl-Terminal Domain of Myo2p Has a Direct Role in Secretory Vesicle Targeting. Ph.D. Thesis, Cornell University, Ithaca, NY.
48. Severin, F., B. Habermann, T. Huffaker and T. Hyman, 2001 Stu2 promotes mitotic spindle elongation in anaphase. J. Cell Biol. 153: 435-442.
49. Sherman, F., 1991 Getting started with yeast. Methods Enzymol. 194: 3-21.
50. Siegers, K., T. Waldmann, M. R. Leroux, K. Grein, A. Shevchenko et al., 1999 Compartmentation of protein folding in vivo: Sequestration of non-native polypeptide by the chaperonin-GimC system. EMBO J. 18: 75-84.
51. Sikorski, R. S., and P. Hieter, 1989 A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics 122: 19-27.
52. Solinger, J. A., D. Pascolini and W. D. Heyer, 1999 Active-site mutations in the Xrn1p exoribonuclease of Saccharomyces cerevisiae reveal a specific role in meiosis. Mol. Cell. Biol. 19: 5930-5942.
53. Stevens, A., C. L. Hsu, K. R. Isham and F. W. Larimer, 1991 Fragments of the internal transcribed spacer 1 of pre-rRNA accumulate in Saccharomyces cerevisiae lacking 5′-3′ exonuclease 1. J. Bacteriol. 173: 7024-7028.
54. Wach, A., A. Brachat, C. Alberti-Segui, C. Rebischung and P. Philippsen, 1997 Heterologous HIS3 marker and GFP reporter modules for PCR-targeting in Saccharomyces cerevisiae. Yeast 13: 1065-1075.
55. Wang, P. J., and T. C. Huffaker, 1997 Stu2p: A microtubule-binding protein that is an essential component of the yeast spindle pole body. J. Cell Biol. 139: 1271-1280.
56. Wilkinson, K. D., V. L. Tashayev, L. B. O'connor, C. N. Larsen, E. Kasperek et al., 1995 Metabolism of the polyubiquitin degradation signal: Structure, mechanism, and role of isopeptidase T. Biochemistry 34: 14535-14546.
57. Yin, H., D. Pruyne, T. C. Huffaker and A. Bretscher, 2000 Myosin V orientates the mitotic spindle in yeast. Nature 406: 1013-1015.