Mast, a conserved microtubule-associated protein required for bipolar mitotic spindle organization

EMBO Journal

Volumn 19, Issue 14, 2000, Pages 3668-3682

  Lemos, Catarina L ^a   Sampaio, Paula ^a   Maiato, Helder ^a   Costa, Madalena ^a   Omel'yanchuk, Leonid V ^b   Liberal, Vasco ^a   Sunkel, Claudio E ^a,c  

^a UNIVERSITY OF PORTO   (Portugal)

^b INSTITUTE OF CYTOLOGY AND GENETICS   (Russian Federation)

^c UNIVERSITY OF PORTO   (Portugal)

Author keywords

Centrosome; Drosophila; MAPs; Microtubules; Mitosis

Indexed keywords

GREEN FLUORESCENT PROTEIN; HYBRID PROTEIN; MICROTUBULE ASSOCIATED PROTEIN;

ANIMAL CELL; ARTICLE; CELL CYCLE; CENTROSOME; DROSOPHILA; GENE EXPRESSION; MICROTUBULE; MITOSIS SPINDLE; MOLECULAR CLONING; NEUROBLAST; NONHUMAN; PRIORITY JOURNAL;

ANIMALIA;

EID: 0034679590     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/19.14.3668     Document Type: Article

References (39)

1. Aizawa, H., Emori, Y., Mori, A., Murofushi, H., Sakai, H. and Suzuli, K. (1991) Functional analysis of the domain structure of microtubule-associated protein-4 (MAP-U). J. Biol. Chem., 266, 9841-9846.
2. Altschul, S.F., Madden, T.L., Schäffer, A.A., Zhang, J., Zhang, Z., Miller, W. and Lipman, D.J. (1997) Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res., 25, 3389-3402.
3. Andrade, M.A. and Bork, P. (1995) HEAT repeats in the Huntington's disease protein. Nature Genet., 11, 115-116.
4. Basu, J., Bousbaa, H., Logarinho, E., Li, Z., Williams, B.C., Lopes, C., Sunkel, C.E. and Goldberg, M.L. (1999) Mutations in the essential spindle checkpoint gene bubl cause chromosome missegregation and fail to block apoptosis in Drosophila. J. Cell Biol., 146, 13-28.
5. Bonaccorsi, S., Giansanti, M.G. and Gatti, M. (2000) Spindle assembly in Drosophila neuroblasts and ganglion mother cells. Nature Cell Biol., 2, 54-56.
6. Bousbaa, H., Correia, L., Gorbsky, G.J. and Sunkel, C.E. (1997) Mitotic phosphoepitopes are expressed in Kc cells, neuroblasts and isolated chromosomes of Drosophila melanogaster. J. Cell Sci., 110, 1979-1988.
7. Charrasse, S.M., Schroeder, M., Gauthier-Rouviere, C., Ango, F., Cassimeris, L., Gard, D.L. and Larroque, C. (1998) The TOGp protein is a new human microtubule-associated protein homologous to the Xenopus XMAP215. J. Cell Sci., 111, 1371-1383.
8. Cullen, C.F., Deák, P., Glover, D.M. and Ohkura, H. (1999) mini spindles: a gene encoding a conserved microtubule-associated protein required for the integrity of the mitotic spindle in Drosophila. J. Cell Biol., 146, 1005-1018.
9. v40) associated with the abnormal chromosome spindle in Drosophila melanogaster. Genetika, 33, 1502-1509.
10. González, C. and Glover, D.M. (1993) Techniques for studying mitosis in Drosophila. In Fantes, P. and. Brookes, R. (eds), The Cell Cycle: A Practical Approach. Oxford University Press, Oxford, pp. 163-168.
11. Gräf, R., Daunderer, C. and Schliwa, M. (2000) Dictyostelium DdCP224 is a microtubule-associated protein and a permanent centrosomal resident involved in centrosome duplication. J Cell Sci., 113, 1747-1758.
12. Hemmings, B.A., Adams-Pearson, C., Maurer, F., Mueller, P., Goris, J., Merlevede, W., Hofsteenge, J. and Stone, S.R. (1990) α-Forms and β-forms of the 65-kDa subunit of protein phosphatase 2A have a similar 39 amino acid repeating structure. Biochemistry, 29, 3166-3173.
13. Heuer, J., Li, K. and Kaufman, T. (1995) The Drosophila homeotic target gene centrosomin (cnn) encodes a novel centrosomal protein with leucine zippers and maps to a genomic region required for midgut morphogenesis. Development, 121, 3861-3876.
14. Ishikawa, K., Nagase, T., Suyama, M., Miyajima, N., Tanaka, A., Kotani, H., Nomura, N. and Ohara, O. (1998) Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. DNA Res., 5, 169-176.
15. Kemphues, K.J., Wolf, N., Wood, W.B. and Hirsh, D. (1986) Two loci required for cytoplasmic organization in early embryos of Caenorhabditis elegans. Dev. Biol., 113, 449-460.
16. Kennelly, P.J. and Krebs, E.G. (1991) Consensus sequences as substrate specificity determinants for protein kinases and protein phosphatases. J. Biol. Chem., 266, 15555-15558.
17. Kung, A.L., Sherwood, S. and Schimke, R.T. (1990) Cell line-specific differences in the control of cell cycle progression in the absence of mitosis. Proc. Natl Acad. Sci. USA, 87, 9553-9557.
18. Logarinho, E. and Sunkel, C.E. (1998) The Drosophila POLO kinase localises to multiple compartments of the mitotic apparatus and is required for the phosphorylation of MPM2 reactive epitopes. J. Cell Sci., 111, 2897-2909.
19. Matthews, L.R., Carter, P., Thierry-Mieg, D. and Kemphues, K. (1998) ZYG-9, a Caenorhabditis elegans protein required for microtubule organisation and function, is a component of meiotic and mitotic spindle poles. J. Cell Biol., 141, 1159-1168.
20. Nabeshima, K., Kurooka, H., Takeuchi, M., Kinoshita, K., Nakaseko, Y. and Yanagida, M. (1995) p93dis1, which is required for sister chromatid separation, is a novel microtubule and spindle pole body-associating protein phosphorylated at the Cdc2 target sites. Genes Dev., 9, 1572-1585.
21. Nakaseko, Y., Nabeshima, K., Kinoshita, K. and Yanagida, M. (1996) Dissection of fission yeast microtubule associating protein p93dis1: regions implicated in regulated localisation and microtubule interaction. Genes Cells, 1, 633-644.
22. Nicklas, R.B. (1997) How cells get the right number of chromosomes. Science, 275. 632-637.
23. Omel'yanchuk, L.V., Volkova, E.I. and Fedorova, S.A. (1997) Characterisation of insertion mutations leading to mitosis abnormalities in Drosophila melanogaster by means of the reporter gene-containing transposon. Genetika, 33, 1494-1501.
24. Pasqualone, D. and Huffaker, T.C. (1994) STU1, a suppressor of a β-tubulin mutation, encodes a novel and essential component of the yeast mitotic spindle. J. Cell Biol., 127, 1973-1984.
25. Retief, J.D. (2000) Phylogenetic analysis using PHYLIP. Methods Mol. Biol., 132, 243-258.
26. Robinson, J.T., Wojcik, E.J., Sanders, M.A., McGrail, M. and Hays, T.S. (1999) Cytoplasmic dynein is required for the nuclear attachment and migration of centrosomes during mitosis in Drosophila. J. Cell Biol., 146, 597-608.
27. Sambrook, J., Fritsch, E.F. and Maniatis, T. (1989) Molecular Cloning: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
28. Saunders, R.D., Avides, M.C., Howard, T., González, C. and Glover, D.M. (1997) The Drosophila gene abnormal spindle encodes a novel microtubule-associated protein that associates with the polar regions of the mitotic spindle. J. Cell Biol., 137, 881-890.
29. Saunders, W.S. and Hoyt, M.A. (1992) Kinesin-related proteins required for structural integrity of the mitotic spindle. Cell, 70, 451-458.
30. Saxton, W.M., Stemple, D.L., Leslie, R.J., Salmon, E.D., Zavortink, M. and McIntosh, J.R. (1984) Tubulin dynamics in cultured mammalian cells. J. Cell Biol., 99, 2175-2186.
31. Sharp, D.J., Yu, K.R., Sisson, J.C., Sullivan, W. and Scholey, J.M. (1999) Antagonistic microtubule-sliding motors position mitotic centrosomes in Drosophila early embryos. Nature Cell Biol., 1, 51-54.
32. Sharp, D.J., Brown, H.M., Kwon, M., Rogers, G.C., Holland, G. and Scholey, J.M. (2000) Functional coordination of three mitotic motors in Drosophila embryos. Mol. Biol. Cell, 11, 241-253.
33. Sunkel, C.E., Gomes, R., Sampaio, P., Perdigão, J. and González, C. (1995) γ-Tubulin is required for the structure and function of the microtubule organising centre in Drosophila neuroblasts. EMBO J., 14, 28-36.
34. Tournebize, R. et al. (2000) Control of microtubule dynamics by the antagonistic activities of XMAP215 and XKCM1 in Xenopus egg extracts. Nature Cell Biol., 2, 13-19.
35. Vasquez, R.J., Gard, D.L. and Cassimeris, L. (1994) XMAP from Xenopus eggs promotes rapid plus end assembly of microtubules and rapid microtubule polymer turnover. J. Cell Biol., 127, 985-993.
36. Verde, F., Dogterom, M., Stelzer, E., Karsenti, E. and Leibler, S. (1992) Control of microtubule dynamics and length by cyclin A-and cyclin B-dependent kinases in Xenopus egg extracts. J. Cell Biol., 118, 1097-1108.
37. Wang, P.J. and Huffaker, T.C. (1997) Stu2p: a microtubule-binding protein that is an essential component of the yeast spindle pole body. J. Cell Biol., 139, 1271-1280.
38. Wilson, R. et al. (1994) 2.2 Mb of contiguous nucleotide sequence from chromosome III of C.elegans. Nature, 368, 32-38.
39. Zimmerman, W., Sparks, C.A. and Doxsey, S.J. (1999) Amorphous no longer: the centrosome comes into focus. Curr. Opin. Cell Biol., 11, 122-128.