Thielavins as glucose-6-phosphatase (G6Pase) inhibitors: Producing strain, fermentation, isolation, structural elucidation and biological activities

Journal of Antibiotics

Volumn 55, Issue 11, 2002, Pages 941-951

  Sakemi, Shinichi ^a   Hirai, Hideo ^a   Ichiba, Toshio ^b   Inagaki, Taisuke ^a   Kato, Yoshinao ^a   Kojima, Nakao ^c   Nishida, Hiroyuki ^a   Parker, Janice C ^d   Saito, Toshiyuki ^a   Tonai Kachi, Hiroko ^a   VanVolkenburg, Maria A ^d   Yoshikawa, Nobuji ^a   Kojima, Yasuhiro ^a  

^a PFIZER INC   (United States)

^b Okinawa Industrial Technology Center   (Japan)

^c MEIJO UNIVERSITY   (Japan)

^d PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; ANTIDIABETIC AGENT; BENZOIC ACID; CARBOXYLIC ACID; CJ 20 556; CJ 20 557; CJ 20 558; ENZYME INHIBITOR; GLUCAGON; GLUCOSE; GLUCOSE 6 PHOSPHATASE; LIVER ENZYME; TELOMERASE INHIBITOR; THIELAVIN A; THIELAVIN B; THIELAVIN C; THIELAVIN D; THIELAVIN DERIVATIVE; THIELAVIN F; THIELAVIN G; THIELAVIN H; THIELAVIN I; THIELAVIN J; THIELAVIN K; THIELAVIN L; THIELAVIN M; THIELAVIN N; THIELAVIN O; THIELAVIN P; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANIMAL CELL; ARTICLE; CELL STIMULATION; CHAETOMIUM; CONTROLLED STUDY; DRUG HYDROLYSIS; DRUG IDENTIFICATION; DRUG ISOLATION; DRUG POTENCY; DRUG RESEARCH; DRUG SCREENING; ENZYME INHIBITION; FUNGAL STRAIN; GLUCONEOGENESIS; IC 50; LIVER CELL; NONHUMAN; PRIORITY JOURNAL; RAT; STRUCTURE ACTIVITY RELATION;

CHAETOMIUM CARINTHIACUM;

EID: 0036858670     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.7164/antibiotics.55.941     Document Type: Article

References (21)

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