Chemoenzymatic synthesis of the four diastereoisomers of 4-hydroxypipecolic acid from N-acetyl-(R,S)-allylglycine: Chiral scaffolds for drug discovery

Organic Process Research and Development

Volumn 6, Issue 6, 2002, Pages 762-766

  Lloyd, Richard C ^a   Smith, Mark E B ^a   Brick, Dean ^a   Taylor, Stephen J C ^a   Chaplin, David A ^a   McCague, Raymond ^a  

^a Chirotech Technology Limited   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

4 HYDROXYPIPECOLIC ACID; ALLYLGLYCINE; AMIDASE; IMINE; PIPECOLIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

CATALYSIS; CHIRALITY; CONFERENCE PAPER; CRYSTALLIZATION; CYCLIZATION; DIASTEREOISOMER; DRUG SYNTHESIS; HYDROLYSIS; PARTITION COEFFICIENT; STEREOISOMERISM;

EID: 0036858543     PISSN: 10836160     EISSN: None     Source Type: Journal    
DOI: 10.1021/op020017x     Document Type: Conference Paper

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