메뉴 건너뛰기




Volumn 22, Issue 21, 2002, Pages 9643-9650

Effects of furosemide applied chronically to the round window: A model of metabolic presbyacusis

Author keywords

Aging; Compound action potentials; Endocochlear potential; Gerbil; Hearing; Otoacoustic emissions; Presbyacusis

Indexed keywords

FUROSEMIDE;

EID: 0036849702     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.22-21-09643.2002     Document Type: Article
Times cited : (128)

References (63)
  • 2
    • 0028789727 scopus 로고
    • Distortion-product otoacoustic emissions in Mongolian gerbils with resistance to noise-induced hearing loss
    • Boettcher FA, Schmiedt RA (1995) Distortion-product otoacoustic emissions in Mongolian gerbils with resistance to noise-induced hearing loss. J Acoust Soc Am 98:3215-3222.
    • (1995) J Acoust Soc Am , vol.98 , pp. 3215-3222
    • Boettcher, F.A.1    Schmiedt, R.A.2
  • 3
    • 0028221304 scopus 로고
    • Influence of aging on cochlear micromechanical properties and on the medial olivocochlear system in humans
    • Castor X, Veuillet E, Morgon A, Collet L (1994) Influence of aging on cochlear micromechanical properties and on the medial olivocochlear system in humans. Hear Res 77:1-8.
    • (1994) Hear Res , vol.77 , pp. 1-8
    • Castor, X.1    Veuillet, E.2    Morgon, A.3    Collet, L.4
  • 4
    • 0017343847 scopus 로고
    • Neuroanatomical aspects of the gerbil's inner ear: Light microscopic observations
    • Chamberlain SC (1977) Neuroanatomical aspects of the gerbil's inner ear: Light microscopic observations. J Comp Neurol 171:193-204.
    • (1977) J Comp Neurol , vol.171 , pp. 193-204
    • Chamberlain, S.C.1
  • 5
    • 0030818858 scopus 로고    scopus 로고
    • Mechanical responses to two-tone distortion products in the apical and basal turns of the mammalian cochlea
    • Cooper NP, Rhode WS (1997) Mechanical responses to two-tone distortion products in the apical and basal turns of the mammalian cochlea. J Neurophysiol 78:261-270.
    • (1997) J Neurophysiol , vol.78 , pp. 261-270
    • Cooper, N.P.1    Rhode, W.S.2
  • 6
    • 0026442163 scopus 로고
    • The active cochlea
    • Dallos P (1992) The active cochlea. J Neurosci 12:4575-4585.
    • (1992) J Neurosci , vol.12 , pp. 4575-4585
    • Dallos, P.1
  • 7
    • 0016936668 scopus 로고
    • Compound action potential (AP) tuning curves
    • Dallos P, Cheatham MA (1976) Compound action potential (AP) tuning curves. J Acoust Soc Am 59:591-597.
    • (1976) J Acoust Soc Am , vol.59 , pp. 591-597
    • Dallos, P.1    Cheatham, M.A.2
  • 8
    • 0017716756 scopus 로고
    • Analog of two-tone suppression in whole nerve responses
    • Dallos P, Cheatham MA (1977) Analog of two-tone suppression in whole nerve responses. J Acoust Soc Am 62:1048-1051.
    • (1977) J Acoust Soc Am , vol.62 , pp. 1048-1051
    • Dallos, P.1    Cheatham, M.A.2
  • 9
    • 0020692334 scopus 로고
    • An active process in cochlear mechanics
    • Davis H (1983) An active process in cochlear mechanics. Hear Res 9:79-90.
    • (1983) Hear Res , vol.9 , pp. 79-90
    • Davis, H.1
  • 10
    • 0020000214 scopus 로고
    • The effects of intracochlear and systemic furosemide on the properties of single cochlear nerve fibres in the cat
    • Evans EF, Klinke R (1982) The effects of intracochlear and systemic furosemide on the properties of single cochlear nerve fibres in the cat. J Physiol (Lond) 331:409-428.
    • (1982) J Physiol (Lond) , vol.331 , pp. 409-428
    • Evans, E.F.1    Klinke, R.2
  • 12
    • 0036154529 scopus 로고    scopus 로고
    • Effects of age on the distortion product otoacoustic emission growth functions
    • Gates GA, Mills DM, Nam B-H, D'Agostino R, Rubel EW (2001) Effects of age on the distortion product otoacoustic emission growth functions. Hear Res 163:53-60.
    • (2001) Hear Res , vol.163 , pp. 53-60
    • Gates, G.A.1    Mills, D.M.2    Nam, B.-H.3    D'Agostino, R.4    Rubel, E.W.5
  • 13
    • 0028888419 scopus 로고
    • Alterations in microvasculature are associated with atrophy of the stria vascularis in quiet-aged gerbils
    • Gratton MA, Schulte BA (1995) Alterations in microvasculature are associated with atrophy of the stria vascularis in quiet-aged gerbils. Hear Res 82:44-52.
    • (1995) Hear Res , vol.82 , pp. 44-52
    • Gratton, M.A.1    Schulte, B.A.2
  • 14
    • 0030026717 scopus 로고    scopus 로고
    • Age-related decreases in endocochlear potential are associated with vascular abnormalities in the stria vascularis
    • Gratton MA, Schmiedt RA, Schulte BA (1996) Age-related decreases in endocochlear potential are associated with vascular abnormalities in the stria vascularis. Hear Res 94:116-124.
    • (1996) Hear Res , vol.94 , pp. 116-124
    • Gratton, M.A.1    Schmiedt, R.A.2    Schulte, B.A.3
  • 15
    • 0030963031 scopus 로고    scopus 로고
    • Decline in the endocochlear potential corresponds to decreased Na,KATPase activity in the lateral wall of quiet-aged gerbils
    • Gratton MA, Smythe BJ, Lam CF, Boettcher FA, Schmiedt RA (1997) Decline in the endocochlear potential corresponds to decreased Na,KATPase activity in the lateral wall of quiet-aged gerbils. Hear Res 108:9-16.
    • (1997) Hear Res , vol.108 , pp. 9-16
    • Gratton, M.A.1    Smythe, B.J.2    Lam, C.F.3    Boettcher, F.A.4    Schmiedt, R.A.5
  • 16
    • 0018749213 scopus 로고
    • Forward masking of auditory nerve fiber responses
    • Harris DM, Dallos PJ (1979) Forward masking of auditory nerve fiber responses. J Neurophysiol 42:1083-1107.
    • (1979) J Neurophysiol , vol.42 , pp. 1083-1107
    • Harris, D.M.1    Dallos, P.J.2
  • 17
    • 0030063598 scopus 로고    scopus 로고
    • Effects of aging on the fine structure of the 2f1-f2 acoustic distortion product
    • He N, Schmiedt RA (1996) Effects of aging on the fine structure of the 2f1-f2 acoustic distortion product. J Acoust Soc Am 99:1002-1015.
    • (1996) J Acoust Soc Am , vol.99 , pp. 1002-1015
    • He, N.1    Schmiedt, R.A.2
  • 18
    • 0025606049 scopus 로고
    • Compound action potential input/output functions in young and quiet-aged gerbils
    • Hellstrom LI, Schmiedt RA (1990) Compound action potential input/output functions in young and quiet-aged gerbils. Hear Res 50:163-174.
    • (1990) Hear Res , vol.50 , pp. 163-174
    • Hellstrom, L.I.1    Schmiedt, R.A.2
  • 19
    • 0029858040 scopus 로고    scopus 로고
    • Measures of tuning and suppression in single-fiber and whole-nerve responses in young and quiet-aged gerbils
    • Hellstrom LI, Schmiedt RA (1996) Measures of tuning and suppression in single-fiber and whole-nerve responses in young and quiet-aged gerbils. J Acoust Soc Am 100:3275-3285.
    • (1996) J Acoust Soc Am , vol.100 , pp. 3275-3285
    • Hellstrom, L.I.1    Schmiedt, R.A.2
  • 20
    • 0033991594 scopus 로고    scopus 로고
    • Age-related changes in the murine cochlear lateral wall
    • Ichimiya I, Suzuki M, Mogi G (2000) Age-related changes in the murine cochlear lateral wall. Hear Res 139:116-122.
    • (2000) Hear Res , vol.139 , pp. 116-122
    • Ichimiya, I.1    Suzuki, M.2    Mogi, G.3
  • 22
    • 0024571768 scopus 로고
    • Spiral ganglion cell density in young and old gerbils
    • Keithley EM, Ryan AF, Woolf NK (1989) Spiral ganglion cell density in young and old gerbils. Hear Res 38:125-134.
    • (1989) Hear Res , vol.38 , pp. 125-134
    • Keithley, E.M.1    Ryan, A.F.2    Woolf, N.K.3
  • 23
    • 0031193888 scopus 로고    scopus 로고
    • Interpretation of distortion product otoacoustic emission measurements. I. Two stimulus tones
    • Mills DM (1997a) Interpretation of distortion product otoacoustic emission measurements. I. Two stimulus tones. J Acoust Soc Am 103:413-429.
    • (1997) J Acoust Soc Am , vol.103 , pp. 413-429
    • Mills, D.M.1
  • 24
    • 0031972804 scopus 로고    scopus 로고
    • Interpretation of distortion product otoacoustic emission measurements. II. Emission tuning characteristics using three stimulus tones
    • Mills DM (1997b) Interpretation of distortion product otoacoustic emission measurements. II. Emission tuning characteristics using three stimulus tones. J Acoust Soc Am 103:507-523.
    • (1997) J Acoust Soc Am , vol.103 , pp. 507-523
    • Mills, D.M.1
  • 25
    • 0034025667 scopus 로고    scopus 로고
    • Frequency responses of two- and three-tone distortion product otoacoustic emissions in Mongolian gerbils
    • Mills DM (2000) Frequency responses of two- and three-tone distortion product otoacoustic emissions in Mongolian gerbils. J Acoust Soc Am 107:2586-2602.
    • (2000) J Acoust Soc Am , vol.107 , pp. 2586-2602
    • Mills, D.M.1
  • 26
    • 0028271935 scopus 로고
    • Variation of distortion product otoacoustic emissions with furosemide injection
    • Mills DM, Rubel EW (1994) Variation of distortion product otoacoustic emissions with furosemide injection. Hear Res 77:183-199.
    • (1994) Hear Res , vol.77 , pp. 183-199
    • Mills, D.M.1    Rubel, E.W.2
  • 27
    • 0027525462 scopus 로고
    • Vulnerability and adaptation of distortion product otoacoustic emissions to endocochlear potential variation
    • Mills DM, Norton SJ, Rubel EW (1993) Vulnerability and adaptation of distortion product otoacoustic emissions to endocochlear potential variation. J Acoust Soc Am 94:2108-2122.
    • (1993) J Acoust Soc Am , vol.94 , pp. 2108-2122
    • Mills, D.M.1    Norton, S.J.2    Rubel, E.W.3
  • 28
    • 0342973225 scopus 로고    scopus 로고
    • The cochlear place-frequency map of the adult and developing mongolian gerbil
    • Müller M (1996) The cochlear place-frequency map of the adult and developing mongolian gerbil. Hear Res 94:148-156.
    • (1996) Hear Res , vol.94 , pp. 148-156
    • Müller, M.1
  • 29
    • 0021926256 scopus 로고
    • Influence of direct current on DC receptor potentials from cochlear inner hair cells in the guinea pig
    • Nuttall AL (1985) Influence of direct current on DC receptor potentials from cochlear inner hair cells in the guinea pig. J Acoust Soc Am 77:165-175.
    • (1985) J Acoust Soc Am , vol.77 , pp. 165-175
    • Nuttall, A.L.1
  • 31
    • 0031834609 scopus 로고    scopus 로고
    • Acoustical modulation of electrically evoked otoacoustic emission in intact gerbil cochlea
    • Ren T, Nuttall AL (1998) Acoustical modulation of electrically evoked otoacoustic emission in intact gerbil cochlea. Hear Res 120:7-16.
    • (1998) Hear Res , vol.120 , pp. 7-16
    • Ren, T.1    Nuttall, A.L.2
  • 32
    • 0034963407 scopus 로고    scopus 로고
    • Mechanics of the mammalian cochlea
    • Robles L, Ruggero MA (2001) Mechanics of the mammalian cochlea. Physiol Rev 81:1305-1352.
    • (2001) Physiol Rev , vol.81 , pp. 1305-1352
    • Robles, L.1    Ruggero, M.A.2
  • 33
    • 0028864682 scopus 로고
    • Effects of furosemide on distortion product otoacoustic emissions and on neural responses in the anteroventral cochlear nucleus
    • Rubsamen R, Mills DM, Rubel EW (1995) Effects of furosemide on distortion product otoacoustic emissions and on neural responses in the anteroventral cochlear nucleus. J Neurophysiol 74:1628-1638.
    • (1995) J Neurophysiol , vol.74 , pp. 1628-1638
    • Rubsamen, R.1    Mills, D.M.2    Rubel, E.W.3
  • 34
    • 0026046327 scopus 로고
    • Furosemide alters organ of Corti mechanics: Evidence for feedback of outer hair cells upon the basilar membrane
    • Ruggero MA, Rich NC (1991) Furosemide alters organ of Corti mechanics: Evidence for feedback of outer hair cells upon the basilar membrane. J Neurosci 11:1057-1067.
    • (1991) J Neurosci , vol.11 , pp. 1057-1067
    • Ruggero, M.A.1    Rich, N.C.2
  • 35
    • 0020699619 scopus 로고
    • Origin of the receptor potential in inner hair cells of the mammalian cochlea-evidence for Davis's theory
    • Russell IJ (1983) Origin of the receptor potential in inner hair cells of the mammalian cochlea-evidence for Davis's theory. Nature 301:334-336.
    • (1983) Nature , vol.301 , pp. 334-336
    • Russell, I.J.1
  • 36
    • 0020044861 scopus 로고
    • Pathophysiology of furosemide ototoxicity
    • Rybak LP (1982) Pathophysiology of furosemide ototoxicity. J Otolaryngol 11:127-133.
    • (1982) J Otolaryngol , vol.11 , pp. 127-133
    • Rybak, L.P.1
  • 37
    • 0027496033 scopus 로고
    • Ototoxicity of loop diuretics
    • Rybak LP (1993) Ototoxicity of loop diuretics. Otolaryngol Clin North Am 26:829-844.
    • (1993) Otolaryngol Clin North Am , vol.26 , pp. 829-844
    • Rybak, L.P.1
  • 38
    • 0019951901 scopus 로고
    • Effect of furosemide upon endolymph potassium concentration
    • Rybak LP, Morizono T (1982) Effect of furosemide upon endolymph potassium concentration. Hear Res 2:223-231.
    • (1982) Hear Res , vol.2 , pp. 223-231
    • Rybak, L.P.1    Morizono, T.2
  • 39
    • 0026568132 scopus 로고
    • Effects of organic acids on the edema of the stria vascularis induced by furosemide
    • Rybak LP, Whitworth C, Weberg A, Scott V (1992) Effects of organic acids on the edema of the stria vascularis induced by furosemide. Hear Res 59:75-84.
    • (1992) Hear Res , vol.59 , pp. 75-84
    • Rybak, L.P.1    Whitworth, C.2    Weberg, A.3    Scott, V.4
  • 41
    • 0034989252 scopus 로고    scopus 로고
    • Quantification of solute entry into cochlear perilymph through the round window membrane
    • Salt AN, Ma Y (2001) Quantification of solute entry into cochlear perilymph through the round window membrane. Hear Res 154:88-97.
    • (2001) Hear Res , vol.154 , pp. 88-97
    • Salt, A.N.1    Ma, Y.2
  • 42
    • 0034904775 scopus 로고    scopus 로고
    • Furosemide alters nonlinear capacitance in isolated outer hair cells
    • Santos-Sacchi J, Wu M, Kakehata S (2001) Furosemide alters nonlinear capacitance in isolated outer hair cells. Hear Res 159:69-73.
    • (2001) Hear Res , vol.159 , pp. 69-73
    • Santos-Sacchi, J.1    Wu, M.2    Kakehata, S.3
  • 43
    • 0022491799 scopus 로고
    • Acoustic distortion in the ear canal. I. Cubic difference tones: Effects of acute noise injury
    • Schmiedt RA (1986) Acoustic distortion in the ear canal. I. Cubic difference tones: Effects of acute noise injury. J Acoust Soc Am 79:1481-1490.
    • (1986) J Acoust Soc Am , vol.79 , pp. 1481-1490
    • Schmiedt, R.A.1
  • 44
    • 0001770191 scopus 로고
    • Cochlear potentials in quiet-aged gerbils: Does the aging cochlea need a jump start?
    • (Verrillo R, ed), Hillsdale, NJ: Erlbaum
    • Schmiedt RA (1993) Cochlear potentials in quiet-aged gerbils: Does the aging cochlea need a jump start? In: Sensory research: Multimodal perspectives. (Verrillo R, ed), Hillsdale, NJ: Erlbaum.
    • (1993) Sensory Research: Multimodal Perspectives
    • Schmiedt, R.A.1
  • 45
    • 0030561487 scopus 로고    scopus 로고
    • Effects of aging on potassium homeostasis and the endocochlear potential in the gerbil
    • Schmiedt RA (1996) Effects of aging on potassium homeostasis and the endocochlear potential in the gerbil. Hear Res 102:125-132.
    • (1996) Hear Res , vol.102 , pp. 125-132
    • Schmiedt, R.A.1
  • 46
    • 24444463607 scopus 로고
    • Ear-canal acoustic emissions as frequency-specific indicators of cochlear function
    • Schmiedt RA, Addy CL (1982) Ear-canal acoustic emissions as frequency-specific indicators of cochlear function. J Acoust Soc Am 72:S6.
    • (1982) J Acoust Soc Am , vol.72
    • Schmiedt, R.A.1    Addy, C.L.2
  • 47
    • 0003065762 scopus 로고
    • Physiologic and histopathologic changes in quiet- and noise-aged gerbil cochleas
    • Dancer AL, Henderson D, Salvi RJ, Hamernik RP, eds. Toronto: Decker
    • Schmiedt RA, Schulte BA (1992) Physiologic and histopathologic changes in quiet- and noise-aged gerbil cochleas. In: Noise Induced Hearing Loss (Dancer AL, Henderson D, Salvi RJ, Hamernik RP, eds), pp 246-256. Toronto: Decker.
    • (1992) Noise Induced Hearing Loss , pp. 246-256
    • Schmiedt, R.A.1    Schulte, B.A.2
  • 48
    • 0017328169 scopus 로고
    • Comparison of sound-transmission and cochlear-microphonic characteristics in Mongolian gerbil and guinea pig
    • Schmiedt RA, Zwislocki JJ (1977) Comparison of sound-transmission and cochlear-microphonic characteristics in Mongolian gerbil and guinea pig. J Acoust Soc Am 61:133-149.
    • (1977) J Acoust Soc Am , vol.61 , pp. 133-149
    • Schmiedt, R.A.1    Zwislocki, J.J.2
  • 49
    • 0018884551 scopus 로고
    • Effects of hair cell lesions on responses of cochlear nerve fibers. I. Lesions, tuning curves, two-tone inhibition, and responses to trapezoidal-wave patterns
    • Schmiedt RA, Zwislocki JJ, Hamernik RP (1980) Effects of hair cell lesions on responses of cochlear nerve fibers. I. Lesions, tuning curves, two-tone inhibition, and responses to trapezoidal-wave patterns. J Neurophysiol 43:1367-1389.
    • (1980) J Neurophysiol , vol.43 , pp. 1367-1389
    • Schmiedt, R.A.1    Zwislocki, J.J.2    Hamernik, R.P.3
  • 50
    • 0025335398 scopus 로고
    • Tuning and suppression in auditory nerve fibers of aged gerbils raised in quiet or noise
    • Schmiedt RA, Mills JH, Adams JC (1990) Tuning and suppression in auditory nerve fibers of aged gerbils raised in quiet or noise. Hear Res 45:221-236.
    • (1990) Hear Res , vol.45 , pp. 221-236
    • Schmiedt, R.A.1    Mills, J.H.2    Adams, J.C.3
  • 51
    • 0029957980 scopus 로고    scopus 로고
    • Age-related loss of activity of auditory-nerve fibers
    • Schmiedt RA, Mills JH, Boettcher FA (1996) Age-related loss of activity of auditory-nerve fibers. J Neurophysiol 76:2799-2803.
    • (1996) J Neurophysiol , vol.76 , pp. 2799-2803
    • Schmiedt, R.A.1    Mills, J.H.2    Boettcher, F.A.3
  • 54
    • 0026700889 scopus 로고
    • Lateral wall Na,K-ATPase and endocochlear potentials decline with age in quiet-reared gerbils
    • Schulte BA, Schmiedt RA (1992) Lateral wall Na,K-ATPase and endocochlear potentials decline with age in quiet-reared gerbils. Hear Res 61:35-46.
    • (1992) Hear Res , vol.61 , pp. 35-46
    • Schulte, B.A.1    Schmiedt, R.A.2
  • 55
    • 0021187468 scopus 로고
    • The effects of furosemide on the endocochlear potential and auditory-nerve fiber tuning curves in cats
    • Sewell W (1984a) The effects of furosemide on the endocochlear potential and auditory-nerve fiber tuning curves in cats. Hear Res 14:305-314.
    • (1984) Hear Res , vol.14 , pp. 305-314
    • Sewell, W.1
  • 56
    • 0021286988 scopus 로고
    • The relation between the endocochlear potential and spontaneous activity in auditory nerve fibres of the cat
    • Sewell W (1984b) The relation between the endocochlear potential and spontaneous activity in auditory nerve fibres of the cat. J Physiol (Lond) 347:685-696.
    • (1984) J Physiol (Lond) , vol.347 , pp. 685-696
    • Sewell, W.1
  • 57
    • 0021241775 scopus 로고
    • Furosemide selectively reduces one component in rate-level functions from auditory-nerve fibers
    • Sewell W (1984c) Furosemide selectively reduces one component in rate-level functions from auditory-nerve fibers. Hear Res 15:69-72.
    • (1984) Hear Res , vol.15 , pp. 69-72
    • Sewell, W.1
  • 58
    • 0034121374 scopus 로고    scopus 로고
    • Study of afferent nerve terminals and fibers in the gerbil cochlea: Distribution by size
    • Slepecky NB, Galsky MD, Swartzentruber-Martin H, Savage J (2000) Study of afferent nerve terminals and fibers in the gerbil cochlea: Distribution by size. Hear Res 144:124-134.
    • (2000) Hear Res , vol.144 , pp. 124-134
    • Slepecky, N.B.1    Galsky, M.D.2    Swartzentruber-Martin, H.3    Savage, J.4
  • 59
    • 0030994997 scopus 로고    scopus 로고
    • Quantitative measures of hair cell loss in CBA and C57BL/6 mice throughout their life spans
    • Spongr VP, Flood DG, Frisina RD, Salvi RJ (1997) Quantitative measures of hair cell loss in CBA and C57BL/6 mice throughout their life spans. J Acoust Soc Am 101:3546-3553.
    • (1997) J Acoust Soc Am , vol.101 , pp. 3546-3553
    • Spongr, V.P.1    Flood, D.G.2    Frisina, R.D.3    Salvi, R.J.4
  • 60
    • 0035664383 scopus 로고    scopus 로고
    • Auditory nerve fibers in young and aged gerbils: Morphometric correlations with endocochlear potential
    • Suryadevara AC, Schulte BA, Schmiedt RA, Slepecky NB (2001) Auditory nerve fibers in young and aged gerbils: Morphometric correlations with endocochlear potential. Hear Res 161:45-53.
    • (2001) Hear Res , vol.161 , pp. 45-53
    • Suryadevara, A.C.1    Schulte, B.A.2    Schmiedt, R.A.3    Slepecky, N.B.4
  • 62
    • 0027483768 scopus 로고
    • Acoustic enhancement of electrically evoked otoacoustic emissions reflects basilar-membrane tuning: Experimental results
    • Xue S, Mountain DC, Hubbard AE (1993) Acoustic enhancement of electrically evoked otoacoustic emissions reflects basilar-membrane tuning: Experimental results. Hear Res 70:121-126.
    • (1993) Hear Res , vol.70 , pp. 121-126
    • Xue, S.1    Mountain, D.C.2    Hubbard, A.E.3
  • 63
    • 0029560913 scopus 로고
    • Acoustic enhancement of electrically evoked otoacoustic emissions reflects basilar-membrane tuning: A model
    • Xue S, Mountain DC, Hubbard AE (1995) Acoustic enhancement of electrically evoked otoacoustic emissions reflects basilar-membrane tuning: A model. Hear Res 91:93-100.
    • (1995) Hear Res , vol.91 , pp. 93-100
    • Xue, S.1    Mountain, D.C.2    Hubbard, A.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.