Age-related decreases in endocochlear potential are associated with vascular abnormalities in the stria vascularis

Hearing Research

Volumn 94, Issue 1-2, 1996, Pages 116-124

  Gratton, M A ^a   Schmiedt, R A ^a   Schulte, B A ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

Aging; Cochlea; Endocochlear potential; Morphometry; Pathology; Stria vascularis

Indexed keywords

AGING; ANIMAL TISSUE; ARTICLE; COCHLEA POTENTIAL; FEMALE; GERBIL; MALE; MORPHOMETRICS; NONHUMAN; PRIORITY JOURNAL; STRIA VASCULARIS;

EID: 0030026717     PISSN: 03785955     EISSN: None     Source Type: Journal    
DOI: 10.1016/0378-5955(96)00011-1     Document Type: Article

References (23)

1. Brechtelsbauer, P.B., Prazma, J., Garrett, C.G., Carrasco, V.N. and Pillsbury, H.C. (1990) Catecholaminergic innervation of the inner ear. Otolaryngol. Head Neck Surg. 103, 566-574.
2. Cannon, M.W. Jr. (1976) Electrical Impedances, Current Pathways and Voltage Sources in the Guinea Pig Cochlea. Unpublished dissertation.
3. Cowley, R.A. and Trump, B.F. (1982) Pathophysiology of Shock, Anoxia and Ischemia. Williams and Wilkins, Baltimore, MD.
4. Davis, H. (1965) A model for transducer action in the cochlea. Cold Springs Harbor Symp. Quant. Biol. 30, 181-190.
5. Gratton, M.A. and Schulte, B.A. (1995) Alterations in microvasculature are associated with atrophy of the stria vascularis in quiet-aged gerbils. Hear. Res. 82, 44-52.
6. Gratton, M.A., Smyth, B.J., Lam, C.F., Boettcher, F.A. and Schmiedt, R.A. (submitted for publication) Decline in the endocochlear potential correlates with decreasing Na,K-ATPase activity in the lateral wall of aged Mongolian gerbils.
7. Hildesheimer, M., Rubinstein, M., Nuttal, A.L. and Lawrence, M. (1982) Influence of blood viscosity on cochlear action potentials and oxygenation. Hear. Res. 8, 187-198.
8. Honrubia, V. and Ward, P.H. (1969) Dependence of the cochlear microphonic and the summating potential on the endocochlear potential. J. Acoust. Soc. Am. 46, 388-392.
9. Igarashi, M., Alford, B.R., Konishi, S. Shaver, E.F. and Guilford, F.R. (1969) Functional and histopathological correlations after microembolism of the peripheral labyrinthine artery in the dog. Laryngoscope 79, 603-623.
10. Johnsson, L.G. and Hawkins, J.E. Jr. (1972) Vascular changes in the human inner ear associated with aging. Ann. Otol. 81, 364-376.
11. Kimura, R.S. and Ota, C.Y. (1974) Ultrastructure of the cochlear blood vessels. Acta Otolaryngol. 77, 231-250.
12. Kimura, R.S. and Perlman, H.B. (1956) Extensive venous obstruction of the labyrinth. A. Cochlear changes. Ann. Otol. Rhinol. Laryngol. 65, 332-350.
13. Kimura, R.S. and Perlman, H.B. (1958) Arterial obstruction of the labyrinth. I. Cochlear changes. Ann. Otol. Rhinol. Laryngol. 76, 5-24.
14. Konishi T., Butler, R.A. and Fernandez, C. (1961) Effect of anoxia on cochlear potentials. J. Acoust. Soc. Am. 33, 349-356.
15. Lyons, M.J. and Wanamaker, H.H. (1993) Blood flow and assessment of capillaries in the aging rat posterior canal crista. Hear. Res. 67, 157-165.
16. Mills, J.H., Schmiedt, R.A. and Kulish, L.F. (1990) Age-related changes in auditory potentials of Mongolian gerbil. Hear. Res. 46, 201-210.
17. Prazma, J., Carrasco, V.M., Butler, B., Waters G., Anderson T. and Pillsbury, H.C. (1990) Cochlear microcirculation in young and old gerbils. Arch. Otoloryngol. Head Neck Surg. 116, 932-936.
18. Schmiedt, R.A. (1993) Cochlear potentials in quiet-aged gerbils: Does the aging cochlea need a jump start?. In: R.T. Verillo (Ed.), Sensory Research Multimodal Perspectives. Lawrence Erlbaum, Hillsdale, NJ, pp. 91-103.
19. Schmiedt, R.A. and Zwislocki, J.J. (1977) Comparison of sound-transmission and cochlear-microphonic characteristics in Mongolian gerbil and guinea pigs. J. Acoust. Soc. Am. 61, 133-149.
20. Schulte, B.A. and Schmiedt, R.A. (1992) Lateral wall Na,K-ATPase and endocochlear potentials decline with age in quiet-reared animals. Hear. Res. 61, 35-46.
21. Takahashi, T. (1971) The ultrastructure of the pathologic stria vascularis and spiral prominence in man. Ann. Otol. 80, 721-735.
22. Tarnowski, B.I., Schmiedt, R.A., Hellstrom, L.I., Lee, F.S. and Adams, J.C. (1991) Age-related changes in cochleas of Mongolian gerbils. Hear. Res. 54, 123-134.
23. Thalmann, R., Miyoshi, T. and Thalmann, I. (1972) The influence of ischemia upon energy reserves of inner ear tissues. Laryngoscope, 82, 2249-2272.