메뉴 건너뛰기




Volumn 88, Issue 5, 2002, Pages 2262-2279

Rhythmic properties of neurons in the rostral ventrolateral medulla of the rat in vitro: Effects of clonidine

Author keywords

[No Author keywords available]

Indexed keywords

CLONIDINE; RAUWOLSCINE; YOHIMBINE;

EID: 0036847885     PISSN: 00223077     EISSN: None     Source Type: Journal    
DOI: 10.1152/jn.00085.2002     Document Type: Article
Times cited : (5)

References (48)
  • 1
    • 0027132794 scopus 로고
    • α2-adrenoceptor-mediated inhibition of bulbospinal barosensitive cells of rat rostral medulla
    • Allen AM and Guyenet PG. α2-Adrenoceptor-mediated inhibition of bulbospinal barosensitive cells of rat rostral medulla. Am J Physiol 34: R1065-R1075, 1993.
    • (1993) Am J Physiol , vol.34
    • Allen, A.M.1    Guyenet, P.G.2
  • 2
    • 0021830036 scopus 로고
    • Axonal projection patterns of ventrolateral medullospinal sympathoexcitatory neurons
    • Barman SM and Gebber GL. Axonal projection patterns of ventrolateral medullospinal sympathoexcitatory neurons. J Neurophysiol 53: 1551-1566, 1985.
    • (1985) J Neurophysiol , vol.53 , pp. 1551-1566
    • Barman, S.M.1    Gebber, G.L.2
  • 3
    • 0033810786 scopus 로고    scopus 로고
    • "Rapid" rhythmic discharges of sympathetic nerves: Sources, mechanisms of generation, and physiological relevance
    • Barman SM and Gebber GL. "Rapid" rhythmic discharges of sympathetic nerves: Sources, mechanisms of generation, and physiological relevance. J Biol Rhythms 15: 365-379, 2000.
    • (2000) J Biol Rhythms , vol.15 , pp. 365-379
    • Barman, S.M.1    Gebber, G.L.2
  • 6
    • 0025753287 scopus 로고
    • Effects of clonidine on sympathoexcitatory neurons in the rostral ventrolateral medulla
    • Clement ME and McCall RB. Effects of clonidine on sympathoexcitatory neurons in the rostral ventrolateral medulla. Brain Res 550: 353-357, 1991.
    • (1991) Brain Res , vol.550 , pp. 353-357
    • Clement, M.E.1    McCall, R.B.2
  • 7
    • 0025267255 scopus 로고
    • Role of imidazole receptors in the vasodepressor response to clonidine analogs in the rostral ventrolateral medulla
    • Ernsberger P, Giuliano R, Willette RN, and Reis DJ. Role of imidazole receptors in the vasodepressor response to clonidine analogs in the rostral ventrolateral medulla. J Pharmacol Exp Ther 253: 408-418, 1990.
    • (1990) J Pharmacol Exp Ther , vol.253 , pp. 408-418
    • Ernsberger, P.1    Giuliano, R.2    Willette, R.N.3    Reis, D.J.4
  • 9
    • 0023109845 scopus 로고
    • Clonidine binds to imidazoline binding sites as well as α2-adrenoceptors in the ventrolateral medulla
    • Ernsberger P, Meeley MP, Mann JJ, and Reis DJ. Clonidine binds to imidazoline binding sites as well as α2-adrenoceptors in the ventrolateral medulla. Eur J Pharmacol 134: 1-13, 1987.
    • (1987) Eur J Pharmacol , vol.134 , pp. 1-13
    • Ernsberger, P.1    Meeley, M.P.2    Mann, J.J.3    Reis, D.J.4
  • 10
    • 0011482174 scopus 로고
    • Catecholaminergic mechanisms involved in the inhibition of pacemaker-like type II neurons in the rostral ventrolateral medulla (RVLM) in vitro
    • Granata AR. Catecholaminergic mechanisms involved in the inhibition of pacemaker-like type II neurons in the rostral ventrolateral medulla (RVLM) in vitro. Soc Neurosci Abstr 20: 1181, 1994.
    • (1994) Soc Neurosci Abstr , vol.20 , pp. 1181
    • Granata, A.R.1
  • 11
    • 0002528177 scopus 로고
    • Electrophysiological and anatomical characterization of barosensitive neurons in the rostral ventrolateral medulla
    • edited by Trouth CO, Millis RM, Kiwull-Schone H, and Schlafke ME. New York: Marcel Dekker
    • Granata AR. Electrophysiological and anatomical characterization of barosensitive neurons in the rostral ventrolateral medulla. In: Ventral Brain-stem Mechanisms and Control of Respiration and Blood Pressure, edited by Trouth CO, Millis RM, Kiwull-Schone H, and Schlafke ME. New York: Marcel Dekker, 1995, pp 837-871.
    • (1995) Ventral Brain-stem Mechanisms and Control of Respiration and Blood Pressure , pp. 837-871
    • Granata, A.R.1
  • 12
    • 0026536188 scopus 로고
    • Intracellular analysis in vivo of different barosensitive bulbospinal neurons in the rat rostral ventrolateral medulla
    • Granata AR and Kitai ST. Intracellular analysis in vivo of different barosensitive bulbospinal neurons in the rat rostral ventrolateral medulla. J Neurosci 12: 1-20, 1992.
    • (1992) J Neurosci , vol.12 , pp. 1-20
    • Granata, A.R.1    Kitai, S.T.2
  • 13
    • 0022479714 scopus 로고
    • A1 noradrenergic neurons tonically inhibit sympathoexcitatory neurons of C1 area in rat brainstem
    • Granata AR, Numao Y, Kumada M, and Reis DJ. A1 noradrenergic neurons tonically inhibit sympathoexcitatory neurons of C1 area in rat brainstem. Brain Res 377: 127-146, 1986.
    • (1986) Brain Res , vol.377 , pp. 127-146
    • Granata, A.R.1    Numao, Y.2    Kumada, M.3    Reis, D.J.4
  • 14
    • 0026094064 scopus 로고
    • Pharmacological characterization of rat α2-adrenergic receptors
    • Harrison JK, D'Angelo DD, Zeng DW, and Lynch KR. Pharmacological characterization of rat α2-adrenergic receptors. Mol Pharmacol 40: 407-412, 1991.
    • (1991) Mol Pharmacol , vol.40 , pp. 407-412
    • Harrison, J.K.1    D'Angelo, D.D.2    Zeng, D.W.3    Lynch, K.R.4
  • 15
    • 0033954007 scopus 로고    scopus 로고
    • Prototypical imidazoline-1 receptor ligand moxonidine activates alpha2-adrenoceptors in bulbospinal neurons of the RVLM
    • Hayar A and Guyenet PG. Prototypical imidazoline-1 receptor ligand moxonidine activates alpha2-adrenoceptors in bulbospinal neurons of the RVLM. J Neurophysiol 83: 766-776, 2000.
    • (2000) J Neurophysiol , vol.83 , pp. 766-776
    • Hayar, A.1    Guyenet, P.G.2
  • 16
    • 0027378949 scopus 로고
    • Mediation of the hypotensive action of systemic clonidine in the rat by alpha2-adrenoceptors
    • Hieble JP and Kolpak DC. Mediation of the hypotensive action of systemic clonidine in the rat by alpha2-adrenoceptors. Br J Pharmacol 110: 1635-1639, 1993.
    • (1993) Br J Pharmacol , vol.110 , pp. 1635-1639
    • Hieble, J.P.1    Kolpak, D.C.2
  • 17
    • 0028817649 scopus 로고
    • Whole-cell recordings from visualized C1 adrenergic bulbospinal neurons: Ionic mechanisms underlying vasomotor tone
    • Kangrga IM and Loewy AD. Whole-cell recordings from visualized C1 adrenergic bulbospinal neurons: Ionic mechanisms underlying vasomotor tone. Brain Res 670: 215-232, 1995.
    • (1995) Brain Res , vol.670 , pp. 215-232
    • Kangrga, I.M.1    Loewy, A.D.2
  • 18
    • 0017923173 scopus 로고
    • Central α-adrenergic systems as target for hypotensive drugs
    • Kobinger W. Central α-adrenergic systems as target for hypotensive drugs. Rev Physiol Biochem Pharmacol 81: 39-100, 1978.
    • (1978) Rev Physiol Biochem Pharmacol , vol.81 , pp. 39-100
    • Kobinger, W.1
  • 19
    • 0027278787 scopus 로고
    • The actions of 5-hydroxytryptamine on the membrane of putative sympatho-excitatory neurones in the rostral ventrolateral medulla of the adult rat in vitro
    • Lewis DI and Coote JH. The actions of 5-hydroxytryptamine on the membrane of putative sympatho-excitatory neurones in the rostral ventrolateral medulla of the adult rat in vitro. Brain Res 609: 103-109, 1993.
    • (1993) Brain Res , vol.609 , pp. 103-109
    • Lewis, D.I.1    Coote, J.H.2
  • 21
    • 0030047717 scopus 로고    scopus 로고
    • Properties of presympathetic neurones in the rostral ventrolateral medulla in the rat: An intracellular study 'in vivo.'
    • Lipski J, Kanjhan R, Kruszewska B, and Rong W. Properties of presympathetic neurones in the rostral ventrolateral medulla in the rat: An intracellular study 'in vivo.' J Physiol (Lond) 490: 729-744, 1996.
    • (1996) J Physiol (Lond) , vol.490 , pp. 729-744
    • Lipski, J.1    Kanjhan, R.2    Kruszewska, B.3    Rong, W.4
  • 22
    • 0029777474 scopus 로고    scopus 로고
    • Central hypotensive effects of the α2a-adrenergic receptor subtype
    • MacMillan LB, Hein L, Smith MS, Piascik MT, and Limbird LE. Central hypotensive effects of the α2a-adrenergic receptor subtype. Science 273: 801-803, 1996.
    • (1996) Science , vol.273 , pp. 801-803
    • MacMillan, L.B.1    Hein, L.2    Smith, M.S.3    Piascik, M.T.4    Limbird, L.E.5
  • 23
    • 0023923188 scopus 로고
    • Phenylethanolamine N-methyltransferase-containing terminals synapse directly on sympathetic preganglionic neurons in the rat
    • Milner TA, Morrison SF, Abate C, and Reis DJ. Phenylethanolamine N-methyltransferase-containing terminals synapse directly on sympathetic preganglionic neurons in the rat. Brain Res 448: 205-222, 1988.
    • (1988) Brain Res , vol.448 , pp. 205-222
    • Milner, T.A.1    Morrison, S.F.2    Abate, C.3    Reis, D.J.4
  • 24
    • 0033528320 scopus 로고    scopus 로고
    • Alpha2A-adrenergic receptors are primarily presynaptic heteroreceptors in the C 1 area of the rat rostral ventrolateral medulla
    • Milner TA, Rosin DL, Lee A, and Aicher SA. Alpha2A-adrenergic receptors are primarily presynaptic heteroreceptors in the C1 area of the rat rostral ventrolateral medulla. Brain Res 821: 200-211, 1999.
    • (1999) Brain Res , vol.821 , pp. 200-211
    • Milner, T.A.1    Rosin, D.L.2    Lee, A.3    Aicher, S.A.4
  • 25
    • 0034735734 scopus 로고    scopus 로고
    • Three types of putative presympathetic neurons in the rostral ventrolateral medulla studied with rat brainstem-spinal cord preparation
    • Oshima N, Kumagai H, Kawai A, Sakata MK, Matsuura T, and Saruta T. Three types of putative presympathetic neurons in the rostral ventrolateral medulla studied with rat brainstem-spinal cord preparation. Autonom Neurosci 84: 40-49, 2000.
    • (2000) Autonom Neurosci , vol.84 , pp. 40-49
    • Oshima, N.1    Kumagai, H.2    Kawai, A.3    Sakata, M.K.4    Matsuura, T.5    Saruta, T.6
  • 27
    • 0032526520 scopus 로고    scopus 로고
    • Lability of the pacemaker activity in the rat rostro-ventrolateral medulla: Effects of noradrenaline
    • Piguet P and Schlichter R. Lability of the pacemaker activity in the rat rostro-ventrolateral medulla: Effects of noradrenaline. Brain Res 796: 1-12, 1998.
    • (1998) Brain Res , vol.796 , pp. 1-12
    • Piguet, P.1    Schlichter, R.2
  • 28
    • 0030768503 scopus 로고    scopus 로고
    • Pharmacology and clinical use of moxonidine, a new centrally acting sympatholytic antihypertensive agent
    • Prichard BN, Owens CW, and Graham BR. Pharmacology and clinical use of moxonidine, a new centrally acting sympatholytic antihypertensive agent. J Human Hypertens 11: S29-S45, 1997.
    • (1997) J Human Hypertens , vol.11
    • Prichard, B.N.1    Owens, C.W.2    Graham, B.R.3
  • 29
    • 0029830118 scopus 로고    scopus 로고
    • Neurons and receptors in the rostroventrolateral medulla mediating the antihypertensive actions of drugs acting at imidazoline receptors
    • Reis DJ. Neurons and receptors in the rostroventrolateral medulla mediating the antihypertensive actions of drugs acting at imidazoline receptors. J Cardiovasc Pharmacol 27: S11-S18, 1996.
    • (1996) J Cardiovasc Pharmacol , vol.27
    • Reis, D.J.1
  • 31
    • 0015542438 scopus 로고
    • Action of α-adrenergic blocking drugs on the sympathetic centres and their interactions with the central sympatho-inhibitory effect of clonidine
    • Schmitt H, Schmitt H, and Fenard S. Action of α-adrenergic blocking drugs on the sympathetic centres and their interactions with the central sympatho-inhibitory effect of clonidine. Arzneimittel-Forschung 23: 40-45, 1973.
    • (1973) Arzneimittel Forschung , vol.23 , pp. 40-45
    • Schmitt, H.1    Schmitt, H.2    Fenard, S.3
  • 32
    • 0033667878 scopus 로고    scopus 로고
    • Role of presympathetic C1 neurons in the sympatholytic and hypotensive effects of clonidine in rats
    • Schreihofer AM and Guyenet PG. Role of presympathetic C1 neurons in the sympatholytic and hypotensive effects of clonidine in rats. Am J Physiol 279: R1753-R1762, 2000.
    • (2000) Am J Physiol , vol.279
    • Schreihofer, A.M.1    Guyenet, P.G.2
  • 33
    • 0017095771 scopus 로고
    • Short-term synchronization of intercostal motoneutone activity
    • Sears TA and Stagg D. Short-term synchronization of intercostal motoneutone activity. J Physiol (Lond) 263: 357-381, 1976.
    • (1976) J Physiol (Lond) , vol.263 , pp. 357-381
    • Sears, T.A.1    Stagg, D.2
  • 34
    • 0028868690 scopus 로고
    • Central neural organization and control of sympathetic nervous system in mammals
    • Sun M-K. Central neural organization and control of sympathetic nervous system in mammals. Prog Neurobiol 47: 157-233, 1995.
    • (1995) Prog Neurobiol , vol.47 , pp. 157-233
    • Sun, M.-K.1
  • 35
    • 0022543893 scopus 로고
    • Effects of clonidine and gamma-aminobutyric acid on the discharges of medullo-spinal sympathoexcitatory neurons in the rat
    • Sun M-K and Guyenet PG. Effects of clonidine and gamma-aminobutyric acid on the discharges of medullo-spinal sympathoexcitatory neurons in the rat. Brain Res 368: 1-17, 1986.
    • (1986) Brain Res , vol.368 , pp. 1-17
    • Sun, M.-K.1    Guyenet, P.G.2
  • 36
    • 0025055336 scopus 로고
    • Excitation of rostral medullary pacemaker neurons with putative sympathoexcitatory function by cyclic AMP and α-adrenoceptor agonists 'in vitro.'
    • Sun M-K and Guyenet PG. Excitation of rostral medullary pacemaker neurons with putative sympathoexcitatory function by cyclic AMP and α-adrenoceptor agonists 'in vitro.' Brain Res 511: 30-40, 1990.
    • (1990) Brain Res , vol.511 , pp. 30-40
    • Sun, M.-K.1    Guyenet, P.G.2
  • 37
    • 0023868450 scopus 로고
    • Sympathoexcitatory neurons of rostral ventrolateral medulla exhibit pacemaker properties in the presence of a glutamate-receptor antagonist
    • Sun M-K, Hackett JT, and Guyenet PG. Sympathoexcitatory neurons of rostral ventrolateral medulla exhibit pacemaker properties in the presence of a glutamate-receptor antagonist. Brain Res 438: 23-40, 1988a.
    • (1988) Brain Res , vol.438 , pp. 23-40
    • Sun, M.-K.1    Hackett, J.T.2    Guyenet, P.G.3
  • 38
    • 0028179211 scopus 로고
    • 2+ currents in pacemaker neutones of rat rostral ventrolateral medulla in vitro
    • 2+ currents in pacemaker neutones of rat rostral ventrolateral medulla in vitro. J Physiol (Lond) 476: 101-116, 1994.
    • (1994) J Physiol (Lond) , vol.476 , pp. 101-116
    • Sun, M.-K.1    Reis, D.J.2
  • 39
    • 0023838568 scopus 로고
    • Reticulospinal pace-maker neurons of the rat rostral ventrolateral medulla with putative sympathoexcitatory function: An intracellular study in vitro
    • Sun M-K, Young BS, Hackett JT, and Guyenet PG. Reticulospinal pace-maker neurons of the rat rostral ventrolateral medulla with putative sympathoexcitatory function: An intracellular study in vitro. Brain Res 442: 229-239, 1988b.
    • (1988) Brain Res , vol.442 , pp. 229-239
    • Sun, M.-K.1    Young, B.S.2    Hackett, J.T.3    Guyenet, P.G.4
  • 40
    • 0019504836 scopus 로고
    • Characterization of α-adrenoceptors participating in the central hypotensive and sedative effects of clonidine, using yohimbine, rauwolscine and corynanthine
    • Timmermans PBM, Schoop AMC, Kwa HY, and Van Zwieten PA. Characterization of α-adrenoceptors participating in the central hypotensive and sedative effects of clonidine, using yohimbine, rauwolscine and corynanthine. Eur J Pharmacol 70: 7-15, 1981.
    • (1981) Eur J Pharmacol , vol.70 , pp. 7-15
    • Timmermans, P.B.M.1    Schoop, A.M.C.2    Kwa, H.Y.3    Van Zwieten, P.A.4
  • 41
    • 0025608009 scopus 로고
    • Evidence for clonidine presynaptically modulating amino acid release in the rostral ventral medulla: Role in hypertension
    • Tingley FD and Arneric SP. Evidence for clonidine presynaptically modulating amino acid release in the rostral ventral medulla: role in hypertension. Brain Res 537: 175-181, 1990.
    • (1990) Brain Res , vol.537 , pp. 175-181
    • Tingley, F.D.1    Arneric, S.P.2
  • 42
    • 0021396341 scopus 로고
    • Distribution of α2 agonist binding sites in the rat and human central nervous system: Analysis of some functional, anatomical correlates of the pharmacologic effects of clonidine and related adrenergic agents
    • Unnerstall JR, Kopajtic TA, and Kuhar MJ. Distribution of α2 agonist binding sites in the rat and human central nervous system: Analysis of some functional, anatomical correlates of the pharmacologic effects of clonidine and related adrenergic agents. Brain Res 319: 69-101, 1984.
    • (1984) Brain Res , vol.319 , pp. 69-101
    • Unnerstall, J.R.1    Kopajtic, T.A.2    Kuhar, M.J.3
  • 43
    • 0032802705 scopus 로고    scopus 로고
    • Centrally acting antihypertensive drugs. Present and future
    • Van Zwieten PA. Centrally acting antihypertensive drugs. Present and future. Clin Exp Hypertens 21: 859-873, 1999.
    • (1999) Clin Exp Hypertens , vol.21 , pp. 859-873
    • Van Zwieten, P.A.1
  • 44
    • 0026465310 scopus 로고
    • Yohimbine as a serotonergic agent: Evidence from receptor binding and drug discrimination
    • Winter JC and Rabin RA. Yohimbine as a serotonergic agent: Evidence from receptor binding and drug discrimination. J Pharmacol Exp Ther 263: 682-689, 1992.
    • (1992) J Pharmacol Exp Ther , vol.263 , pp. 682-689
    • Winter, J.C.1    Rabin, R.A.2
  • 45
    • 0023145844 scopus 로고
    • Long-term modifiability of anomalous and delayed rectification in guinea pig inferior olivary neurons
    • Yarom Y and Llinas R. Long-term modifiability of anomalous and delayed rectification in guinea pig inferior olivary neurons. J Neurosci 7: 1166-1177, 1987.
    • (1987) J Neurosci , vol.7 , pp. 1166-1177
    • Yarom, Y.1    Llinas, R.2
  • 46
    • 0027253966 scopus 로고
    • Monosynaptic projections from the rostral ventrolateral medulla oblongata to identified sympathetic preganglionic neurons
    • Zagon A and Smith AD. Monosynaptic projections from the rostral ventrolateral medulla oblongata to identified sympathetic preganglionic neurons. Neuroscience 54: 729-743, 1993.
    • (1993) Neuroscience , vol.54 , pp. 729-743
    • Zagon, A.1    Smith, A.D.2
  • 47
    • 0030445852 scopus 로고    scopus 로고
    • Stimulation of aortic nerve evokes three different response patterns in neurons of rostral VLM of the rat
    • Zagon A and Spyer KM. Stimulation of aortic nerve evokes three different response patterns in neurons of rostral VLM of the rat. Am J Physiol 271: R1720-R1728, 1996.
    • (1996) Am J Physiol , vol.271
    • Zagon, A.1    Spyer, K.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.