Survival characteristics and age-adjusted disease incidences in C57BL/6 mice fed a commonly used cereal-based diet modulated by dietary restriction

Journals of Gerontology - Series A Biological Sciences and Medical Sciences

Volumn 57, Issue 11, 2002, Pages B379-B389

  Turturro, Angelo ^a   Duffy, Peter ^a   Hass, Bruce ^a   Kodell, Ralph ^a   Hart, Ronald ^b  

^a NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

^b Toxicology and Industrial Health   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENAL CORTEX ADENOMA; AGING; ANGIOSARCOMA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY WEIGHT; BONE ATROPHY; BREAST TUMOR; CENTRAL NERVOUS SYSTEM DISEASE; CEREAL; CONTROLLED STUDY; DIET RESTRICTION; DISEASE COURSE; FEMALE; FOOD INTAKE; HEART DISEASE; HEMANGIOMA; HEMATOLOGIC DISEASE; HYPERPLASIA; HYPOPHYSIS TUMOR; INFLAMMATION; KIDNEY DISEASE; LIVER TUMOR; LONGEVITY; LUNG ALVEOLUS CELL CARCINOMA; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PYODERMA GANGRENOSUM; SURVIVAL TIME;

AGING; ANIMAL FEED; ANIMALS; BODY WEIGHT; CEREALS; DIET; DISEASE SUSCEPTIBILITY; FEMALE; FOOD DEPRIVATION; LONGEVITY; MALE; MICE; MICE, INBRED C57BL; SURVIVAL RATE;

ANIMALIA;

EID: 0036847345     PISSN: 10795006     EISSN: None     Source Type: Journal    
DOI: 10.1093/gerona/57.11.B379     Document Type: Article

References (72)

1. Weindruch R, Walford R. The Retardation of Aging and Disease by Dietary Restriction. Springfield, IL: Charles C Thomas; 1988.
2. Blackwell B-N, Bucci T, Hart R, Turturro A, Longevity, body weight, and neoplasia in ad libitum fed and diet-restricted C57BL6 mice fed NIH-31 open formula diet. Toxicol Pathol. 1995;23:570-582.
3. Sheldon W, Bucci T. Blackwell B, Turturro A. Effect of ad libitum feeding and 40% feed restriction on body weight, longevity, and neoplasms in B6C3F1, C57BL6, and B6D2F1 mice. In: Mohr U, Dungworth D, Capen C, Carlton W, Sundberg J, Ward J, eds. Pathobiology of the Aging Mouse. Vol. 1. Washington, DC: ILSI Press; 1996:21-26.
4. Hart R, Dixit R, Seng J, et al. Adaptive role of caloric intake on degenerative disease processes. Toxicol Sci. 1999;52(suppl 2):3-12.
5. Berg B, Simms H. Nutrition and longevity in the rat. 3. Longevity and onset of disease with different levels of food intake. J Nutr. 1960;71: 255-263.
6. Gerbase-De Lima M, Liu RK, Cheney KE, Mickey R, Walford RL. Immune function and survival in a long-lived mouse strain subjected to undernutrition. Gerontologia. 1975;21:184-202.
7. Leto S, Kokkonen GC, Barrows CH Jr. Dietary protein, lifespan and biochemical variables in female mice. J Gerontol. 1976;31: 149-154.
8. Goodrick C. Body weight increment and length of life: The effect of genetic constitution and dietary protein. J Gerontol. 1978;33:184-190.
9. Cheney KE, Liu RK, Smith GS, Leung RE, Mickey MR, Walford RL. Survival and disease patterns in C57BL/6J mice subjected to undernutrition. Exp Gerontol. 1980;15:237-258.
10. Harrison DE, Archer JR, Astle C. Effect of food restriction on aging: Separation of food intake and adiposity. Proc Natl Acad Sci USA. 1984;81:1835-1838.
11. Harrison DE, Archer JR. Genetic differences in effects of food restriction on aging in mice. J Nutr. 1987;117:376-382.
12. NTP (National Toxicology Program). Toxicology and Carcinogenesis Studies of Benzyl Acetate. Research Triangle Park, NC: National Institute of Environmental Health Sciences; 1993. NTP Technical Report (TR) 431.
13. Allaben W, Chou M, Pegram R, et al. Modulation of toxicity and carcinogenicity by caloric restriction. Korean J Toxicol. 1990;6:167-182.
14. Sprott R. Biomarkers of aging. J Gerontol Biol Sci. 1999:54A:B464-B465.
15. Turturro A, Witt W, Lewis S, Hass BS, Lipman RD, Hart R. Growth curves and survival characteristics of the animals used in the biomarkers of aging program. J Gerontol Biol Sci. 1999;54A:B492-B501.
16. Lewis S, Leard B, Turturro A, Hart R. Long-term housing of rodents under specific pathogen-free barrier conditions. In: Yu BP, ed. Methods in Aging Research. Boca Raton, FL: CRC Press; 1999:217-235.
17. Thurman J, Bucci T, Hart R, Turturro A. Survival, body weight, and spontaneous neoplasms in ad libitum fed and dietary restricted Fischer 344 rats. Toxicol Pathol. 1994;22:1-9.
18. Sheldon W, Bucci T, Hart R, Turturro A. Age-related neoplasia in a lifetime study of ad libitum-fed and food restricted B6C3F1 mice. Toxicol Pathol. 1995;23:458-476.
19. Loeb WF, Das S, Harbour L, Turturro A, Bucci T. Clinical biochemistry. In: Mohr U, Dungworth D, Capen C, Carlton W, Sundberg J, Ward J, eds. Pathobiology of the Aging Mouse. Vol. 1. Washington, D.C.: ILSI Press; 1996:3-20.
20. Kaplan EL, Meier P. Nonparametric estimation from incomplete observations. J Am Stat Assoc. 1958;53:457-481.
21. Mantel N. Evaluation of survival data and two new rank-order statistics arising in its consideration. Cancer Chemother Rep. 1966;50:163-170.
22. SAS. SAS/STAT User's Guide. Vol. 2. Cary, NC: SAS Institute; 1990.
23. Kodell R, Ahn H. An age-adjusted trend test for tumor incidence rate for multiple-sacrifice experiments. Biometrics. 1997;53:1467-1474.
24. Peto R, Pike M, Day N, et al. Guidelines for simple, sensitive significance tests for carcinogenic effects in long-term animal experiments. Intl Agency Res Cancer Monog. 1980;(suppl 2):311-426.
25. Squire, R. Criteria for classifying neoplasms and use of data on nonneoplastic lesions. In: Grice H, Cominera J, eds. Carcinogenicity: The Design, Analysis and Interpretation of Long-Term Animal Studies. New York: Springer-Verlag; 1988:107-115.
26. Sprott RL, Austad SN. Animal models for aging research. In: Schneider E, Rowe J, eds. Handbook of the Biology of Aging. San Diego: Academic Press; 1996:3-23.
27. Turturro A, Hart R. Dietary alteration in the rate of cancer and aging. Exp Gerontol. 1992;27:583-592.
28. Turturro A, Blank K, Murasko D, Hart R. Mechanisms of caloric restriction effecting aging and disease. Ann NY Acad Sci. 1994;719:159-170.
29. Gijbels MJ, Jurcher C, Kraal G, et al. Pathogenesis of skin lesions in mice with chronic proliferative dermatitis (cpdm/cpdm). Am J Pathol. 1996;148:941-950.
30. Turturro A, Hart R. Modulation of toxicity by diet: Implications for response at low-level exposures. In: Calabrese E, ed. Biological Effects of Low Level Exposures: Dose-Response Relationships. Chelsea, MI: Lewis Publishers; 1994:143-152.
31. Turturro A, Duffy P, Hart R. Modulation of toxicity by diet and dietary macronutrient restriction. Mutation Res. 1993;295:151-164.
32. Turturro A, Duffy P, Hart R. The effect of caloric modulation on toxicity studies. In: Hart R, Neuman D, Robertson R, eds. Dietary Restriction: Implications for the Design and Interpretation of Toxicity and Carcinogenicity Studies. Washington DC: ILSI Press: 1995:79-98.
33. Turturro A, Duffy P, Hart R, Allaben W. Rationale for the use of dietary control in toxicity studies - B6C3F1 mouse. Toxicol Pathol. 1996;24:769-775.
34. Turturro A, Leakey J, Allaben W, Hart R. Letter to the editor; response to Michael Festing's "fat rats." Nature. 1997;389:326.
35. Turturro A, Hass B, Hart R, Allaben W. Body weight impact on spontaneous and agent-induced diseases in chronic bioassays. Intl J Toxicol. 1998;17:79-100.
36. Holloszy J. Exercise and food restriction in rats. J Nutr. 1992;122 (suppl 3):774-777.
37. Storer J. Chemical protection of the mouse against radiation-induced lifespan shortening. Rad Res. 1971;47:537-547.
38. Goodrick C. Life-span and the inheritance of longevity of inbred mice. J Gerontol. 1975;30:257-263.
39. Lipman R, Bronson R, Wu D, et al. Disease incidence and longevity are unaltered by dietary antioxidant supplementation initiated during middle age in C57 BL/6 mice. Mech Ageing Devel. 1998;103:269-284.
40. Wozniak D, Finger S, Blumenthal H, Poland R. Brain damage, stress and lifespan: An experimental study. J Gerontol. 1982;37:161-168.
41. Kunster I, Leuenberger HW. Gerontological data in C57BL/6J mice. Sex differences in survival curves. J Gerontol. 1975;30:157-162.
42. Weindruch R, Walford RL. Dietary restriction in mice beginning at one year of age: Effects on lifespan and spontaneous tumor incidence. Science. 1982;215:1415-1418.
43. Hirokawa K, Utsuyama M, Goto H, Kuramoto K. Differential rate of age-related decline in immune functions in genetically defined mice with different tumor incidence and lifespan. Gerontology. 1984;30: 223-233.
44. Talan MI, Ingram DK. Effects of intermittent feeding on thermoregulatory abilities of young and aged C57BL/6J mice. Arch Gerontol Geriatr. 1985;4:251-259.
45. Meyer TE, Armstrong M, Warner CM. Effects of H-2 haplotype and gender on the lifespan of A and C57BL/6 mice and the F1, F2, and backcross offspring. Growth Dev Aging. 1989;53:175-183.
46. Nakamura K, Kuramoto K, Shibasaki K, Shimiya S, Ohtsubo K. Age-related incidences of spontaneous tumors in SPF C57BL and BDFI mice. Jikken Dobutsu (Exp An). 1992;41:279-285.
47. Pugh T, Oberly T, Weindruch R. Dietary intervention at middle age: Caloric restriction but not dehydroepiandrosterone sulfate increases lifespan and lifetime cancer incidence in mice. Cancer Res. 1999;59: 1642-1647.
48. Hrubant H, Specific genetic control of the lifespan. J Gerontol. 1964; 19:451-452.
49. Yuhas J. The dose-response curve for radiation-induced life shortening. J Gerontol. 1969;24:451-456.
50. Kohn R. Effects of antioxidants on life-span of C57BL mice. J Gerontol. 1971;26:378-380.
51. Hochschild R. Effects of various drugs on the longevity in female C5BL/6J mice. Gerontologia. 1973;19:271-280.
52. Soave O, Brand D. Coprophagy in animals: A review. Cornell Vet. 1991;81:357-364.
53. Duffy P, Feuers R, Pipkin J, et al. The effect of caloric modulation and aging on the physiological response of rodents to drug toxicity. In: Hart R, Neuman D, Robertson R, eds. Dietary Restriction: Implications for the Design and Interpretation of Toxicity and Carcinogenicity Studies. Washington, DC: ILSI Press: 1995:127-140.
54. Sulkin N, Srivanij P. The experimental production of senile pigments in the nerve cells of young rats. J Gerontol. 1960;15:2-9.
55. Lipman R, Dallal G, Bronson R. Lesion biomarkers of aging in B6C3F1 hybrid mice. J Gerontol Biol Sci. 1999;54A:B466-B477.
56. Sheldon W, Bucci T, Turturro A. Thoracic apophyseal osteoarthritis in feed-restricted and ad libitum fed-B6C3F1 mice. In: Mohr U, Dungworth D, Capen C, Carlton W, Sundberg J, Ward J, eds. Pathobiology of the Aging Mouse. Vol. 1. Washington, DC: ILSI Press; 1996:445-453.
57. Wolf N, Li Y, Pendergrass W, Schmeider C, Turturro A. Normal mouse and rat strains as models for age-related cataract and the effect of caloric restriction on its development. Exp Eye Res. 2000;70:683-692.
58. Means L, Higgins J, Fernandez T. Mid-life onset of dietary restriction extends life and prolongs cognitive functioning. Physiol Behav. 1993; 54:503-508.
59. Dragnev KH, Freemantle SJ, Spinella MJ, Dmitrovsky E. Cyclin proteolysis as a retinoid cancer prevention mechanism. Ann NY Acad Sci. 2001;952:13-22.
60. Rilianawati PT, Kero J, Zhang FP. Rahmen N, Kananen K, Huhtaniemi I. Direct luteinizing hormone action triggers adrenocortical tumorigenesis in castrated mice transgenic for the murine inhibitin alpha-subunit/promotor simian virus 40 T-antigen fusion gene. Mol Endocrinol. 1998;12:801-809.
61. Nelson JF, Felicio LS, Randall PK, Sims C, Finch CE. Longitudinal study of estrous cyclicity in aging C57BL/6 mice. I. Cycle frequency, length and vaginal cytology. Biol Reprod. 1982;27:327-339.
62. Everitt A, Porter BD, Wyndham JR. Effects of caloric intake and dietary composition on the development of proteinuria, age-associated renal disease, and longevity in the male rat. Gerontology. 1982;28: 168-175.
63. Turturro A, Allaben W, Leakey J, Hart R. Modulation of the carcinogenic response by caloric restriction. In: Ioannides C, ed. Nutrition and Chemical Toxicity. Sussex, UK: Wiley; 1998:201-218.
64. Engleman RW, Day NK, Good RA. Calories, parity and prolactin influence mammary epithelial kinetics and differentiation and alter other mouse mammary tumor risk. Cancer Res. 1993;53:1188-1194.
65. Muskhelishvili L, Turturro A, Hart R, Jill JS. π-class glutathione-s-transferase positive hepatocytes in aging B6C3F1 mice undergo apoptosis induced by dietary restriction. Am J Pathol. 1996;149:1585-1591.
66. Giraudo E, Arese M, Toniatti C, et al. IL-6 is an in vitro and in vivo autocrine growth factor for middle T-antigen transformed endothelial cells. J Immunol. 1996;157:2618-2623.
67. Volk MJ, Pugh TD, Kim M, et al. Dietary restriction from middle age attenuates age-associated lymphoma development and interleukin-6 dysregulation in C57BL/6 mice. Cancer Res. 1994;54:3054-3061.
68. Fernandes G. Influence of nutrition on autoimmune disease. In: Goidl E, ed. Aging and the Immune Response. New York: Dekker; 1987: 225-242.
69. Frith C, Ward J, Chandra M. The morphology, immunochemistry and incidence of hematopoietic neoplasms in mice and rats. Toxicol Pathol. 1993;21:206-218.
70. Leakey J, Seng J, Barnas C, Baker V, Hart R. A mechanistic basis for the beneficial effects of caloric restriction on longevity and disease: Consequences for the interpretation of rodent toxicity studies. Intl J Toxicol. 1998;17:5-56.
71. Turturro A, Duffy P, Hart R. Antioxidation and evolution: Dietary restriction and alterations in molecular processes. In: Basu T, Temple N, Garg N, eds. Antioxidants in Human Health and Disease. Oxford: CAB International; 1999:83-94.
72. Poehlman ET, Turturro A, Bodkin N, et al. Caloric restriction mimetics: Physical activity and body composition changes. J Gerontol Biol Sci Med Sci. 2001;56A(Special Issue I):45-54.