The regulation of the thyroid-stimulating hormone of the anterior pituitary gland by thyroid hormone and by 9-Cis-retinoic acid

Nutrition Reviews

Volumn 60, Issue 11, 2002, Pages 374-377

  Wolf, George ^a  

^a Nutrition Reviews Editorial Office   (United States)

Author keywords

9 Cis retinoic acid; Anterior pituitary gland; Retinoid X receptor; Thyroid hormone; Thyroid receptor; Thyroid stimulating hormone; Vitamin A

Indexed keywords

ALITRETINOIN; RETINOID X RECEPTOR; THYROID HORMONE; THYROTROPIN;

GENE ACTIVATION; GENE DISRUPTION; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; HORMONAL REGULATION; HORMONE INHIBITION; HORMONE RECEPTOR INTERACTION; HYPOPHYSIS; MOUSE; NONHUMAN; PROMOTER REGION; REVIEW;

ANIMALS; HUMANS; MICE; MICE, KNOCKOUT; PITUITARY GLAND, ANTERIOR; RECEPTORS, RETINOIC ACID; RECEPTORS, THYROID HORMONE; RETINOID X RECEPTORS; THYROID HORMONES; THYROTROPIN; THYROXINE; TRANSCRIPTION FACTORS; TRETINOIN; TRIIODOTHYRONINE;

EID: 0036846169     PISSN: 00296643     EISSN: None     Source Type: Journal    
DOI: 10.1301/00296640260385919     Document Type: Review

References (12)

1. Simkins S. Use of massive doses of vitamin A in the treatment of hyperthyrodism. J Clin Endocrinol Metab. 1947;7:574-585.
2. Garcin H, Higueret P. Thyroid hormones in vitamin A-deficient rats: Effects of retinoic acid supplementation. Ann Nutr Metab. 1983;27:495-500.
3. Garcin H, Higueret P, Amoikon K. Effects of a large dose of retinol or retinoic acid on the thyroid hormones in the rat. Ann Nutr Metab. 1984;28:92-100.
4. Morley JE, Damassa DA, Gordon J, Pekary AE, Hershman JM. Thyroid function and vitamin A deficiency. Life Sci. 1978;22:1901-1906.
5. Sherman SI, Gopal J, Haugen BR, et al. Central hypothyroidism associated with retinoid X receptor-selective ligands. N Engl J Med. 1999;340:1075-1079.
6. Breen JJ, Hickok NJ, Guff JA. The rat TSHβ gene contains distinct response elements for regulation by retinoids and thyroid hormone. Mol Cell Endocrinol. 1997;131:137-146.
7. Li D, Li T, Wang F, Tian H, Samuels HH. Functional evidence for retinoid X receptor (RXR) as a nonsilent partner in the thyroid hormone receptor/RXR heterodimer. Mol Cell Biol. 2002;22:5782-5792.
8. Haugen BR, Brown NS, Wood WM, Gordon DF, Ridgway EC. The thyrotrope-restricted isoform of the retinoid-X receptor-1γ mediates 9-cis-retinoic acid suppression of thyrotropin-β promoter activity. Mol Endocrinol. 1997;11:481-489.
9. Breen JJ, Matsuura T, Ross AC, Gurr JA. Regulation of thyroid-stimulating hormone beta-subunit and growth hormone messenger ribonucleic acid levels in the rat: Effect of vitamin A status. Endocrinology. 1995;136:543-549.
10. Brown NS, Smart A, Sharma V, et al. Thyroid hormone resistance and increased metabolic rate in the RXR-γ-deficient mouse. J Clin Invest. 2000;106:73-79.
11. -/- mutant mice are viable. Proc Natl Acad Sci U S A. 1996;93:9010-9014.
12. Liu Q, Linney E. The mouse retinoid-X receptor-gamma gene: Genomic organization and evidence for functional forms. Mol Endocrinol. 1993;7:651-658.