Antioxidant treatment decreases the titer of circulating anticardiolipin antibodies: Comment on the article by Sambo et al [8]

Arthritis and Rheumatism

Volumn 46, Issue 11, 2002, Pages 3110-3112

  Ferro, D ^a   Iuliano, L ^a   Violi, F ^a   Valesini, G ^a   Conti, F ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; CARDIOLIPIN ANTIBODY;

ADULT; ANTIBODY TITER; ANTIPHOSPHOLIPID SYNDROME; ARTERY THROMBOSIS; AUTOIMMUNE DISEASE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE ACTIVITY; FEMALE; HUMAN; LETTER; MALE; OXIDATIVE STRESS; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SYSTEMIC LUPUS ERYTHEMATOSUS; THROMBOEMBOLISM; TREATMENT OUTCOME; VEIN THROMBOSIS;

ADULT; ANTIOXIDANTS; ANTIPHOSPHOLIPID SYNDROME; AUTOANTIBODIES; CARDIOLIPINS; FEMALE; HUMANS; MALE; MIDDLE AGED;

EID: 0036845216     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/art.10484     Document Type: Letter

References (6)

1. Sambo P, Baroni SS, Luchetti M, Paroncini P, Dusi S, Orlandini G, et al. Oxidative stress in scleroderma: Maintenance of scleroderma fibroblast phenotype by the constitutive up-regulation of reactive oxygen species generation through the NADPH oxidase complex pathway. Arthritis Rheum 2001;44:2653-64.
2. Horkko S, Miller E, Dudl E, Reaven P, Curtiss LK, Zvaifler NJ, et al. Antiphospholipid antibodies are directed against epitopes of oxidized phospholipids: Recognition of cardiolipin by monoclonal antibodies to epitopes of oxidized low density lipoprotein. J Clin Invest 1996;98:815-25.
3. Iuliano L, Praticò D, Ferro D, Pittoni V, Valesini G, Lawson J, et al. Enhanced lipid peroxidation in patients positive for antiphospholipid antibodies. Blood 1997;90:3931-5.
4. Harris EN, Gharavi AE, Patel SP, Hughes GRV. Evaluation of the anticardiolipin antibody test: Report of an international workshop held 4 April 1986. Clin Exp Immunol 1987;68:214-9.
5. Praticò D, Ferro D, Iuliano L, Rokach J, Conti F, Valesini G, et al. Ongoing prothrombotic state in patients with antiphospholipid antibodies: A role for increased lipid peroxidation. Blood 1999;93:3401-7.
6. Ferro D, Parrotto S, Basili S, Alessandri C, Violi F. Simvastatin inhibits the monocyte expression of proinflammatory cytokines in patients with hypercholesterolemia. J Am Coll Cardiol 2000;36:427-31.