A rapid and sensitive method for the screening of DNA intercalating antibiotics

Biotechnology Letters

Volumn 24, Issue 21, 2002, Pages 1807-1813

  Furlan, Renata Ligia A ^a   Garrido, Leandro M ^a   Brumatti, Gabriela ^a   Amarante Mendes, Gustavo P ^a   Martins, Renata A ^a   Facciotti, Maria Cândida R ^a   Padilla, Gabriel ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Anthracycline; DNA intercalation; Gel mobility shift; Streptomyces

Indexed keywords

STREPTOMYCES; VISCUM; VISCUM ALBUM;

EID: 0036842473     PISSN: 01415492     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1020633909762     Document Type: Article

References (30)

1. Amarante-Mendes GP. Green DR (1999) The regulation of apoptotic cell death. Brazil. J. Med. Biolog. Res. 32: 1053-1061.
2. Arcamone F, Cassinelli G. Fantini G, Grein A, Orezzi P, Pol C, Spalla C (1969a) Adriamycin, 14-hydroxydaunomycin, a new antitumor antibiotic from S. peucetius var. caesius. Biotechnol. Bioeng. 11: 1101-1110.
3. Arcamone F, Franceschi G, Penco S (1969b) Adriamycin (14-hydroxydaunomycin), a novel antitumor antibiotic. Tetrahedron Lett. 13: 1007-1010.
4. Arola JO, Saraste A, Pulkki K, Kalajoki M, Parvinen M, Voipio-Pulkki LM (2000) Acute doxorrubicin cardiotoxicity involves cardiomyocyte apoptosis. Cancer Res. 60: 1789-1792.
5. Chaires JB (1995) Molecular recognition of DNA by daunorubicin. In: Priebe W, ed. Anthracycline Antibiotics. Washington, D.C.: American Chemical Society, pp. 156-167.
6. Culliname C, Rosmalen A, Phillips DR (1994) Does adriamycin induce interstrand crosslinks in DNA? Biochemistry 33: 4632-4638.
7. Cutts SM, Phillips DR (1995) Use of oligonucleotides to define the site of interstrand crosslinks induced by adriamycin. Nucl. Acids Res. 23: 2450-2456.
8. Di Marco A, Gaetani M, Orezzi P, Scarpinato BM, Silvestrini R, Soldati M, Dasdia T, Valentini L (1964) Daunomycin, a new antibiotic of the rhodomycin group. Nature (London) 201: 706-707.
9. Doroshow JH (1995) Role of reactive-oxygen metabolism in cardiac toxicity of anthracycline antibiotics. In: Priebe W, ed. Anthracycline Antibiotics. Washington D.C.: American Chemical Society, pp. 259-267.
10. Drlica K, Franco RJ (1988) Inhibitors of DNA topoisomerases. Biochemistry 27: 2253-2259.
11. Gewirtz DA (1999) A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin. Biochem. Pharm. 57: 727-741.
12. Gibbs JB, Oliff A, Kohl NE (1994) Farnesyl-transferase inhibitors Ras reseach yields a potential cancer therapeutic. Cell 77: 175-178.
13. Haselsberger K, Peterson DC, Thomas DG, Darling JL (1996) Assay of anticancer drugs in tissue culture: Comparison of a tetrazolium-based assay and a protein binding dye assay in short-term cultures derived from human malignant glioma. Anticancer Drugs 7: 331-338.
14. Horenstain MS, Heide RSV, L'Ecuyer, TJ (2000) Molecular basis of antracycline-induced cardiotoxicity and its prevention. Mol. Genet. Metab. 71: 436-444.
15. Hortobágyi GN (1997) Anthracyclines in the treatment of cancer. Drugs 54: 1-7.
16. Hotta K, Zhu CB, Phomsuwansiri P, Ishikida J, Mizuni S, Hatsu M, Imai S (1995) PCR inhibition assay for DNA targeted antibiotics J. Antibiotics 48: 1267-1272.
17. Kieser T, Bibb MJ, Buttner MJ, Chater K.F, Hopwood DA (2000) Practical Streptomyces Genetics. Norwich, UK: The Johnn Innes Foundation.
18. Mendez C, Salas JA (2001) Altering the glycosilation pattern of bioactive compounds. Trends Biotechnol. 19: 449-456.
19. Mirabelli CK, Bartus H, Bartus JOL, Johnson R, Mong SM, Sung CP, Crooke ST (1985) Application of tissue culture microtitre test for the detection of antitumor agents. J. Antibiotics 38: 758-766.
20. Mustonen P, Kinnunen PKJ (1993) On the reversal by deoxyribonucleic acid of the binding of adriamycin to cardiolipin-containing liposomes. J. Biol. Chem. 268: 1074-1080.
21. Nicoletti I, Migliorati G, Pagliacci MC, Grignani F, Riccardi C (1991) A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J. Immunol. Meth. 139: 271-279.
22. Pommier Y (1995) DNA topoisomerases and their inhibition by anthracyclines. In: Priebe W, ed. Anthracycline Antibiotics. Washington D.C.: American Chemical Society, pp. 183-203.
23. Rosmalen A, Culliname C, Cutts SM, Phillips DR (1995) Stability of adriamycin-induced DNA adducts and interstrand crosslinks. Nucl. Acids Res. 23: 42-50.
24. Shadle SE, Bammel BP, Cusack BJ, Knighton RA, Olson SJ, Mushlin PS, Olson RD (2000) Daunorubicin cardiotoxicity. Evidence for the importance of the quinone moiety in a free-radical independent mechanism. Biochem. Pharm. 60: 1435-1444.
25. Shelton CJ, Harding MM, Prakash AS (1996) Enzymatic and chemical footprinting of anthracycline antitumor antibiotics and related saccharide side chains. Biochemistry 35: 7974-7982.
26. Strohl WR, Bartel PL, Connors NC (1990) Biosynthesis of anthracyclines: Analysis de mutantes de Streptomyces sp. strain C5 bloked in daunomycin biosynthesis. J. Gen. Microbiol. 136: 1877-1886.
27. Strohl WR, Dickens ML, Rajgarhia VB, Woo AJ, Priestley ND (1997) Antracyclines. In: Strohl WR, ed. Biotechnology of Antibiotics. New York: M. Dekker. pp. 577-657.
28. Wang JYT, Chao M, Wang AH-J (1995) Adducts of DNA and anthracycline antibiotics: Structures, interactions and activities. In: Priebe W, ed. Anthracycline Antibiotics. Washington D.C.: American Chemical Society, pp. 168-181.
29. Wang H, Mao Y, Zhou N, Hu T, Hsieh TS, Liu LF (2001) ATP-bound topoisomerase II as a target for antitumor drugs. J. Biol. Chem. 276: 15990-15995.
30. Zunino F, Pratesi G, Perego P (2001) Role of the sugar moiety in the pharmacological activity of anthracyclines: Development of a novel series of disaccharide analogs. Biochem. Pharmacol. 61: 933-938.