Diclofenac-induced embryotoxicity is associated with increased embryonic 8-isoprostaglandin F2α level in rat whole embryo culture

Reproductive Toxicology

Volumn 16, Issue 6, 2002, Pages 841-844

  Chan, Louis Yik Si ^a   Chiu, Pui Yu ^a   Siu, Nelson S S ^a   Wang, Chi Chiu ^a   Lau, Tze Kin ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Diclofenac; Lipid peroxidation; Rat whole embryo culture

Indexed keywords

8 ISOPROSTAGLANDIN F2 ALPHA; 8-ISOPROSTAGLANDIN F2ALPHA; ANTI INFLAMMATORY AGENTS, NON STEROIDAL; DICLOFENAC; F2 ISOPROSTANES; ISOPROSTANE DERIVATIVE; NONSTEROID ANTIINFLAMMATORY AGENT; OXYGEN RADICAL;

ANIMAL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONGENITAL MALFORMATION; CONTROLLED STUDY; CROWN RUMP LENGTH; CULTURE MEDIUM; DOSE RESPONSE; DRUG EFFECT; EMBRYO; EMBRYO CULTURE; EMBRYOPATHY; EMBRYOTOXICITY; GESTATIONAL AGE; IN VITRO STUDY; LIPID PEROXIDATION; METABOLISM; MORPHOLOGY; NONHUMAN; ORGAN CULTURE; PATHOGENESIS; PRENATAL DEVELOPMENT; PRENATAL EXPOSURE; RAT; RAT STRAIN; SCORING SYSTEM;

ABNORMALITIES, DRUG-INDUCED; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CROWN-RUMP LENGTH; DICLOFENAC; DINOPROST; DOSE-RESPONSE RELATIONSHIP, DRUG; EMBRYO; EMBRYONIC AND FETAL DEVELOPMENT; F2-ISOPROSTANES; LIPID PEROXIDATION; ORGAN CULTURE TECHNIQUES; RATS; RATS, SPRAGUE-DAWLEY;

ANIMALIA;

EID: 0036841173     PISSN: 08906238     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0890-6238(02)00047-3     Document Type: Article

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