Reduction of urinary 8-epi-prostaglandin F(2α) during cyclo-oxygenase inhibition in rats but not in man

British Journal of Pharmacology

Volumn 121, Issue 8, 1997, Pages 1770-1774

  Bachi, Angela ^a   Brambilla, Raffaella ^a   Fanelli, Roberto ^a   Bianchi, Roberto ^a   Zuccato, Ettore ^a   Chiabrando, Chiara ^a  

^a MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

Author keywords

8 epi PGF(2 ); Cyclo oxygenase; F2 isoprostanes; Indomethacin; Naproxen; Oxidative stress; Prostacyclin; Thromboxane

Indexed keywords

11 OXOTHROMBOXANE B2; 2,3 DINOR 6 OXOPROSTAGLANDIN F1 ALPHA; 2,3 DINORTHROMBOXANE B2; ARACHIDONIC ACID; INDOMETACIN; NAPROXEN; PROSTAGLANDIN F2 ALPHA; PROSTAGLANDIN SYNTHASE; PROSTANOID;

ADULT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARACHIDONIC ACID METABOLISM; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; ENZYME INHIBITION; FEMALE; GAS CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; INTRAPERITONEAL DRUG ADMINISTRATION; LIVER LEVEL; MALE; MASS SPECTROMETRY; NONHUMAN; NORMAL HUMAN; ORAL DRUG ADMINISTRATION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROSTAGLANDIN BLOOD LEVEL; PROSTAGLANDIN SYNTHESIS; PROSTAGLANDIN URINE LEVEL; RAT; SMOKING; URINARY EXCRETION;

ADULT; ANIMALS; CYCLOOXYGENASE INHIBITORS; DINOPROST; FEMALE; HUMANS; INDOMETHACIN; MALE; OXIDATIVE STRESS; PROSTAGLANDINS; RATS; RATS, SPRAGUE-DAWLEY; SPECIES SPECIFICITY;

EID: 0030858511     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0701321     Document Type: Article

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