+1 Proteins and aging

International Journal of Biochemistry and Cell Biology

Volumn 34, Issue 11, 2002, Pages 1502-1505

  Van Leeuwen, F W ^a   Gerez, L ^b   Benne, R ^b   Hol, E M ^a  

^a NETHERLANDS INSTITUTE FOR NEUROSCIENCE   (Netherlands)

^b UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

Alzheimer's disease; Molecular misreading; Proteasome; Ubiquitin

Indexed keywords

MESSENGER RNA; MUTANT PROTEIN; PROTEASOME; TRANSCRIPTION FACTOR;

AGING; ALZHEIMER DISEASE; FRAMESHIFT MUTATION; GENE DELETION; HUMAN; MOLECULAR MECHANICS; NEUROPATHOLOGY; PROTEIN DEGRADATION; PROTEIN FOLDING; PROTEIN FUNCTION; QUALITY CONTROL; REGULATORY MECHANISM; REVIEW; RNA SEQUENCE; RNA TRANSCRIPTION; RNA TRANSLATION;

EID: 0036829576     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1357-2725(02)00043-2     Document Type: Short Survey

References (17)

1. Vogel G. Possible new cause of Alzheimer's disease found. Science. 279:1998;174.
2. van Leeuwen F.W., de Kleijn D.P.V., van den Hurk H.H., Neubauer A., Sonnemans M.A.F., Sluijs J.A., Köycü S., Ramdjielal R.D.J., Salehi A., Martens G.J.M., Grosveld F.G., Burbach J.P.H., Hol E.M. Frameshift mutations of β amyloid precursor protein and ubiquitin B in Alzheimer's and Down patients. Science. 279:1998;242-247.
3. van den Hurk W.H., Willems H.J., Bloemen M., Martens G.J. Novel frameshift mutations near short simple repeats. J. Biol. Chem. 276:2001;11496-11498.
4. Maquat L.E., Carmichael G.G. Quality control of mRNA function. Cell. 104:2001;173-176.
5. van Leeuwen F.W., Burbach J.P.H., Hol E.M. Mutations in RNA: a first example of molecular misreading in Alzheimer's disease. TINS. 21:1998;331-335.
6. van Leeuwen F.W., Hol E.M., Hermanussen R.W.H., Sonnemans M.A.F., Moraal E., Fischer D.F., Evans D.A.P., Chooi K.-F., Burbach J.P.H., Murphy D. Molecular misreading in non-neuronal cells. FASEB J. 14:2000;1595-1602.
7. van Leeuwen F.W., Verwer R.W.H., Spence H., Evans D.A.P., Burbach J.P.H. The magnocellular neurons of the hypothalamo-neurohypophyseal system display remarkable neuropeptidergic penotypes leading to novel insights in neuronal cell biology. Prog. Brain Res. 119:1998;115-126.
8. Evans D.A.P., van der Kleij A.A.M., Sonnemans M.A.F., Burbach J.P.H., van Leeuwen F.W. Frameshift mutations at two hotspots in vasopressin transcripts in post-mitotic neurons. Proc. Natl. Acad. Sci. U.S.A. 91:1994;6059-6063.
9. van Leeuwen F.W., Fischer D.F., Kamel D., Sluijs J.A., Sonnemans M.A.F., Benne R., Swaab D.F., Salehi A., Hol E.M. Molecular misreading: a new type of transcript mutation expressed during aging. Neurobiol. Aging. 21:2000;879-891.
10. Fergusson J., Landon M., Lowe J., Ward L., van Leeuwen F.W., Mayer R.J. Neurofibrillary tangles in progressive supranuclear palsy brains exhibit immunoreactivity to frameshift mutant ubiquitin B protein. Neurosci. Lett. 279:2000;69-72.
11. Schwarz A.L., Ciechanover A. The ubiquitin-proteasome pathway and pathogenesis of human diseases. Annu. Rev. Med. 50:1999;57-74.
12. Lopez-Salon M., Alonso M., Vianna M.R.M., Viola H., Mello e Souza T., Izquierdo I., Pasquini J.M., Medina J.H. The ubiquitin-proteasome cascade is required for mammalian long-term memory formation. Eur. J. Neurosci. 14:2001;1820-1826.
13. de Vrij F.M.S., Sluijs J.A., Gregori L., Fischer D.F., Hermens W.T.J.M.C., Goldgaber D., Verhaagen J., van Leeuwen F.W., Hol E.M. Mutant ubiquitin expressed in Alzheimer's disease causes neuronal death. FASEB J. 15:2001;2680-2688.
14. Lam Y.A., Pickart C.M., Alban A., Landon M., Jamieson C., Ramage R., Mayer R.J., Layfield R. Inhibition of the ubiquitin proteasome system in Alzheimer's disease. PNAS. 97:2000;9902-9906.
15. K. Lindsten, F.M.S. de Vrij, L.G.G.C. Verhoef, D.F. Fischer, F.W. van Leeuwen, E.M. Hol, M.G. Masucci, N.P. Dantuma, J. Cell Biol. 157 (2002) 417-427.
16. Hersberger M., Santiago-Garcia J., Patarroyo-White S., Yan J., Xu X. A dinucleotide deletion in amyloid precursor protein (APP) mRNA associated with sporadic Alzheimer's disease results in efficient secretion of truncated APP isoforms from neuroblastoma cell cultures. J. Neurochem. 76:2001;1308-1314.
17. L.W. McPhaul, J. Wang, E.M. Hol, M.A.F. Sonnemans, N. Riley, V. Nguyen, Q.X. Yuan, F.W. van Leeuwen, S.W. French, Molecular misreading of the ubiquitin B gene and hepatic Mallory body formation, Gastroenterology, in press.