5-Ethoxymethyl-7-fluoro-3-oxo-1,2,3,5-tetrahydrobenzo [4,5]imidazo[1,2a]pyridine-4-N-(2-fluorophenyl)carboxamide (RWJ-51204), a new nonbenzodiazepine anxiolytic

Journal of Pharmacology and Experimental Therapeutics

Volumn 303, Issue 2, 2002, Pages 777-790

  Dubinsky, Barry ^a   Vaidya, Anil H ^a   Rosenthal, Daniel I ^a   Hochman, Coralie ^a   Crooke, Jeffrey J ^a   Deluca, Samantha ^a   Devine, Ann ^a   Cheo Isaacs, Cathy T ^a   Carter, Alexandre R ^a   Jordan, Alfonzo D ^a   Reitz, Allen B ^a   Shank, Richard P ^a  

^a LLC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; 5 ETHOXYMETHYL 7 FLUORO 3 OXO 1,2,3,5 TETRAHYDROBENZ[4,5]IMIDAZO[1,2 A]PYRIDINE 4 N (2 FLUOROPHENYL)CARBOXAMIDE; ABECARNIL; ALPRAZOLAM; ANXIOLYTIC AGENT; BENZODIAZEPINE DERIVATIVE; BRETAZENIL; CHLORDIAZEPOXIDE; CLONAZEPAM; DIAZEPAM; FLUMAZENIL; IMIDAZENIL; LORAZEPAM; PANADIPLON; RWJ 51204; UNCLASSIFIED DRUG;

ANESTHESIA; ANIMAL EXPERIMENT; ANTICONVULSANT ACTIVITY; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DOSE RESPONSE; DRUG ACTIVITY; DRUG EFFICACY; DRUG POTENCY; DRUG POTENTIATION; DRUG RECEPTOR BINDING; DRUG STRUCTURE; MAZE TEST; MOTOR DYSFUNCTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PSYCHOPHARMACOLOGY; SEDATION; SEIZURE; SQUIRREL MONKEY;

ANIMALS; ANTI-ANXIETY AGENTS; BEHAVIOR, ANIMAL; CENTRAL NERVOUS SYSTEM DEPRESSANTS; CHLORDIAZEPOXIDE; CONFLICT (PSYCHOLOGY); CONSCIOUS SEDATION; CONVULSANTS; DRUG INTERACTIONS; ETHANOL; FLUMAZENIL; GABA MODULATORS; IMIDAZOLES; LORAZEPAM; MALE; MICE; MOTOR ACTIVITY; MUSCULOSKELETAL EQUILIBRIUM; PENTYLENETETRAZOLE; PYRIDONES; RATS; RATS, LONG-EVANS; RECEPTORS, GABA-A; SAIMIRI; SEIZURES;

EID: 0036828048     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.102.036954     Document Type: Article

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