Elevated levels of tumor necrosis factor alpha (TNF-α) in human immunodeficiency virus type 1-transgenic mice: Prevention of death by antibody to TNF-α

Journal of Virology

Volumn 76, Issue 22, 2002, Pages 11710-11714

  De, Swapan K ^a   Devadas, Krishnakumar ^a   Notkins, Abner Louis ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPROTEIN GP 120; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA ANTIBODY;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DEATH; GENE EXPRESSION; GROWTH; HOMOZYGOSITY; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SERUM; SKIN DEFECT; TRANSGENIC MOUSE;

EID: 0036827729     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.76.22.11710-11714.2002     Document Type: Article

References (41)

1. Ahmad, N., and S. Venkatesan. 1988. Nef protein of HIV-1 is a transcriptional repressor of HIV-1 LTR. Science 241:1481-1485.
2. Arany, I., M. Muldrow, and S. K. Tyring. 2001. Correlation between mRNA levels of IL-6 and TNF alpha and progression rate in anal squamous epithelial lesions from HIV-positive men. Anticancer Res. 21:425-428.
3. Arditi, M., W. Kabat, and R. Yogev. 1991. Serum tumor necrosis factor alpha, interleukin 1-beta, p24 antigen concentrations and CD4+ cells at various stages of human immunodeficiency virus 1 infection in children. Pediatr. Infect. Dis. J. 10:450-455.
4. Barrera, P., L. A. Joosten, A. A. den Broeder, L. B. van de Putte, P. L. van Riel, and W. B. van den Berg. 2001. Effects of treatment with a fully human anti-tumour necrosis factor alpha monoclonal antibody on the local and systemic homeostasis of interleukin 1 and TNF alpha in patients with rheumatoid arthritis. Ann. Rheum. Dis. 60:660-669.
5. Baud, V., and M. Karin. 2001. Signal transduction by tumor necrosis factor and its relatives. Trends Cell Biol. 11:372-377.
6. Bergamini, A., E. Faggioli, F. Bolacchi, S. Gessani, L. Cappannoli, I. Uccella, F. Demin, M. Capozzi, R. Cicconi, R. Placido, S. Vendetti, G. M. Colizzi, and G. Rocchi. 1999. Enhanced production of tumor necrosis factor-alpha and interleukin-6 due to prolonged response to lipopolysaccharide in human macrophages infected in vitro with human immunodeficiency virus type 1. J. Infect. Dis. 179:832-842.
7. De, S. K., C. R. Wohlenberg, N. J. Marinos, D. Doodnauth, J. L. Bryant, and A. L. Notkins. 1997. Human chorionic gonadotropin hormone prevents wasting syndrome and death in HIV-1 transgenic mice. J. Clin. Investig. 99:1484-1491.
8. Dickie, P., J. Felser, M. Eckhaus, J. Bryant, J. Silver, N. Marinos, and A. L. Notkins. 1991. HIV-associated nephropathy in transgenic mice expressing HIV-1 genes. Virology 185:109-119.
9. Duh, E. J., W. J. Maury, T. M. Folks, A. S. Fauci, and A. B. Rabson. 1989. Tumor necrosis factor alpha activates human immunodeficiency virus type 1 through induction of nuclear factor binding to the NF-kappa B sites in the long terminal repeat. Proc. Natl. Acad. Sci. USA 86:5974-5978.
10. Franks, R. R., P. E. Ray, C. C. Babbott, J. L. Bryant, A. L. Notkins, T. J. Santoro, and P. E. Klotman. 1995. Maternal-fetal interactions affect growth of human immunodeficiency virus type 1 transgenic mice. Pediatr. Res. 37:56-63.
11. Griffin, G. E., K. Leung, T. M. Folks, S. Kunkel, and G. J. Nabel. 1989. Activation of HIV gene expression during monocyte differentiation by induction of NF-kappa B. Nature 339:70-73.
12. Gualberto, A., M. L. Hixon, T. S. Finco, N. D. Perkins, G. J. Nabel, and A. S. Baldwin, Jr. 1995. A proliferative p53-responsive element mediates tumor necrosis factor alpha induction of the human immunodeficiency virus type 1 long terminal repeat. Mol. Cell. Biol. 15:3450-3459.
13. Hassard, P. V., S. W. Binder, V. Nelson, and E. A. Vasiliauskas. 2001. Anti-tumor necrosis factor monoclonal antibody therapy for gastrointestinal Behcet's disease: A case report. Gastroenterology 120:995-999.
14. Hittinger, G., C. Poggi, E. Delbeke, N. Profizi, and A. Lafeuillade. 1998. Correlation between plasma levels of cytokines and HIV-1 RNA copy number in HIV-infected patients. Infection 26:100-103.
15. Jason, J., E. Gomperts, D. N. Lawrence, R. C. Holman, J. D. Bouhasin, R. Miller, and B. L. Evatt. 1989. HIV and hemophilic children's growth. J. Acquir. Immune Defic. Syndr. 2:277-282.
16. Khanna, K. V., X. F. Yu, D. H. Ford, L. Ratner, J. K. Hildreth, and R. B. Markham. 2000. Differences among HIV-1 variants in their ability to elicit secretion of TNF-alpha. J. Immunol. 164:1408-1415.
17. Klotman, P. E., J. Rappaport, P. Ray, J. B. Kopp, R. Franks, L. A. Bruggeman, and A. L. Notkins. 1995. Transgenic models of HIV-1. AIDS 9:313-324.
18. Kopp, J. B., M. E. Klotman, S. H. Adler, L. A. Bruggeman, P. Dickie, N. J. Marinos, M. Eckhaus, J. L. Bryant, A. L. Notkins, and P. E. Klotman. 1992. Progressive glomerulosclerosis and enhanced renal accumulation of basement membrane components in mice transgenic for human immunodeficiency virus type 1 genes. Proc. Natl. Acad. Sci. USA 89:1577-1581.
19. Kopp, J. B., J. F. Rooney, C. Wohlenberg, N. Dorfman, N. J. Marinos, J. L. Bryant, S. I. Katz, A. L. Notkins, and P. E. Klotman. 1993. Cutaneous disorders and viral gene expression in HIV-1 transgenic mice. AIDS Res. Hum. Retrovir. 9:267-275.
20. Lee, E. G., D. L. Boone, S. Chai, S. L. Libby, M. Chien, J. P. Lodolce, and A. Ma. 2000. Failure to regulate TNF-induced NF-kappa B and cell death responses in A20-deficient mice. Science 289:2350-2354.
21. Lunardi-Iskandar, Y., J. L. Bryant, W. A. Blattner, C. L. Hung, L. Flamand, P. Gill, P. Hermans, S. Birken, and R. C. Gallo. 1998. Effects of a urinary factor from women in early pregnancy on HIV-1, SIV and associated disease. Nat. Med. 4:428-434.
22. Manna, S. K., A. Mukhopadhyay, and B. B. Aggarwal. 2000. Human chorionic gonadotropin suppresses activation of nuclear transcription factor-kappa B and activator protein-1 induced by tumor necrosis factor. J. Biol. Chem. 275:13307-13314.
23. Matthys, P., and A. Billiau. 1997. Cytokines and cachexia. Nutrition 13:763-770.
24. Newell, C. L., A. B. Deisseroth, and G. Lopez-Berestein. 1994. Interaction of nuclear proteins with an AP-1/CRE-like promoter sequence in the human TNF-alpha gene. J. Leukoc. Biol. 56:27-35.
25. Rabbi, M. F., L. Al-Harthi, and K. A. Roebuck. 1997. TNF alpha cooperates with the protein kinase A pathway to synergistically increase HIV-1 LTR transcription via downstream TRE-like cAMP response elements. Virology 237:422-429.
26. Rautonen, J., N. Rautonen, N. L. Martin, R. Philip, and D. W. Wara. 1991. Serum interleukin-6 concentrations are elevated and associated with elevated tumor necrosis factor-alpha and immunoglobulin G and A concentrations in children with HIV infection. AIDS 5:1319-1325.
27. Reuben, J. M., J. A. Turpin, B. N. Lee, M. Doyle, B. Gonik, R. Jacobson, and W. T. Shearer. 1996. Induction of inflammatory cytokines in placental monocytes of gravidae infected with the human immunodeficiency virus type 1. J. Interferon Cytokine Res. 16:963-971.
28. Richard-Miceli, C., and M. Dougados. 2001. Tumour necrosis factor-alpha blockers in rheumatoid arthritis: Review of the clinical experience. BioDrugs 15:251-259.
29. Rizzardi, G. P., W. Barcellini, G. Tambussi, F. Lillo, M. Malnati, L. Perrin, and A. Lazzarin. 1996. Plasma levels of soluble CD30, tumour necrosis factor (TNF)-alpha and TNF receptors during primary HIV-1 infection: Correlation with HIV-1 RNA and the clinical outcome. AIDS 10:F45-F50.
30. Rubinstein, A. 1986. Pediatric AIDS. Curr. Probl. Pediatr. 16:361-409.
31. Schwartz, L. J., Y. St. Louis, R. Wu, A. Wiznia, A. Rubinstein, and P. Saenger. 1991. Endocrine function in children with human immunodeficiency virus infection. Am. J. Dis. Child. 145:330-333.
32. Siegel, S. A., D. J. Shealy, M. T. Nakada, J. Le, D. S. Woulfe, L. Probert, G. Kollias, J. Ghrayeb, J. Vilcek, and P. E. Daddona. 1995. The mouse/human chimeric monoclonal antibody cA2 neutralizes TNF in vitro and protects transgenic mice from cachexia and TNF lethality in vivo. Cytokine 7:15-25.
33. Song, X. Y., L. Zeng, W. Jin, C. M. Pilo, M. E. Frank, and S. M. Wahl. 2000. Suppression of streptococcal cell wall-induced arthritis by human chorionic gonadotropin. Arthritis Rheum. 43:2064-2072.
34. Stancovski, I., and D. Baltimore. 1997. NF-κB activation: The I κB kinase revealed? Cell 91:299-302.
35. Tang, G., Y. Minemoto, B. Dibling, N. H. Purcell, Z. Li, M. Karin, and A. Lin. 2001. Inhibition of JNK activation through NF-kappa B target genes. Nature 414:313-317.
36. Taylor, G. A., E. Carballo, D. M. Lee, W. S. Lai, M. J. Thompson, D. D. Patel, D. I. Schenkman, G. S. Gilkeson, H. E. Broxmeyer, B. F. Haynes, and P. J. Blackshear. 1996. A pathogenetic role for TNF alpha in the syndrome of cachexia, arthritis, and autoimmunity resulting from tristetraprolin (TTP) deficiency. Immunity 4:445-454.
37. Taylor, P. C., R. O. Williams, and R. N. Maini. 2001. Immunotherapy for rheumatoid arthritis. Curr. Opin. Immunol. 13:611-616.
38. Trede, N. S., A. V. Tsytsykova, T. Chatila, A. E. Goldfeld, and R. S. Geha. 1995. Transcriptional activation of the human TNF-alpha promoter by superantigen in human monocytic cells: Role of NF-kappa B. J. Immunol. 155:902-908.
39. Udalova, I. A., J. C. Knight, V. Vidal, S. A. Nedospasov, and D. Kwiatkowski. 1998. Complex NF-kappa B interactions at the distal tumor necrosis factor promoter region in human monocytes. J. Biol. Chem. 273:21178-21186.
40. Van der Meide, P. H., and H. Schellekens. 1996. Cytokines and the immune response. Biotherapy 8:243-249.
41. Yang, X., Y. Chen, and D. Gabuzda. 1999. ERK MAP kinase links cytokine signals to activation of latent HIV-1 infection by stimulating a cooperative interaction of AP-1 and NF-kappa B. J. Biol. Chem. 274:27981-27988.