Endothelial Rho and Rho kinase regulate neutrophil migration via endothelial myosin light chain phosphorylation

Journal of Leukocyte Biology

Volumn 72, Issue 4, 2002, Pages 829-836

  Saito, Hajime ^a   Minamiya, Yoshihiro ^a   Saito, Satoshi ^a   Ogawa, Jun ichi ^a  

^a AKITA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Endothelial cells; Neutrophils; Rho

Indexed keywords

F ACTIN; MYOSIN; MYOSIN LIGHT CHAIN; MYOSIN LIGHT CHAIN KINASE; RHO FACTOR; RHO KINASE;

ARTICLE; CELL MIGRATION; CONTROLLED STUDY; CYTOSKELETON; ENDOTHELIUM; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; HUMAN; HUMAN CELL; INFLAMMATION; NEUTROPHIL; PHOSPHORYLATION; POLYMERIZATION; PRIORITY JOURNAL;

ACTINS; ANIMALS; CELL LINE; CELL MOVEMENT; ENDOTHELIUM, VASCULAR; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MYOSIN LIGHT CHAINS; MYOSIN TYPE II; NEUTROPHILS; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; RABBITS; RHO GTP-BINDING PROTEINS;

EID: 0036826835     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (42)

1. Ohashi, K. L., Tung, D. K., Wilson, J., Zweifach, B. W., Schmid-Schonbein, G. W. (1996) Transvascular and interstitial migration of neutrophils in rat mesentery. Microcirculation 3, 199-210.
2. Albelda, S. M., Smith, C. W., Ward, P. A. (1994) Adhesion molecules and inflammatory injury. FASEB J. 8, 504-512.
3. Woodman, R. C., Reinhardt, P. H., Kanwar, S., Johnston, F. L., Kubes, P. (1993) Effects of human neutrophil elastase (HNE) on neutrophil function in vitro and in inflamed microvessels. Blood 82, 2188-2195.
4. Smith, C. W., Kishimoto, T. K., Abbassi, O., Hughes, B., Rothlein, R., McIntire, L. V., Batcher, E., Anderson, D. C., Abbass, O. (1991) Chemotactic factors regulate lectin adhesion molecule 1 (LECAM-1)-dependent neutrophil adhesion to cytokine-stimulated endothelial cells in vitro. J. Clin. Investig. 87, 609-618.
5. Hakkert, B. C., Kuijpers, T. W., Leeuwenberg, J. F., van Mourik, J. A., Roos, D. (1991) Neutrophil and monocyte adherence to and migration across monolayers of cytokine-activated endothelial cells: the contribution of CD18, ELAM-1, and VLA-4. Blood 78, 2721-2726.
6. Furie, M. B., Tancinco, M. C., Smith, C. W. (1991) Monoclonal antibodies to leukocyte integrins CD11a/CD18 and CD11b/CD18 or intercellular adhesion molecule-1 inhibit chemoattractant-stimulated neutrophil transendothelial migration in vitro. Blood 78, 2089-2097.
7. Smith, C. W., Rothlein, R., Hughes, B. J., Mariscalco, M. M., Rudloff, H. E., Schmalstieg, F. C., Anderson, D. C. (1988) Recognition of an endothelial determinant for CD 18-dependent human neutrophil adherence and transendothelial migration. J. Clin. Investig. 82, 1746-1756.
8. Furie, M. B., Burns, M. J., Tancinco, M. C., Benjamin, C. D., Lobb, R. R. (1992) E-selectin (endothelial-leukocyte adhesion molecule-1) is not required for the migration of neutrophils across IL-1-stimulated endothelium in vitro. J. Immunol. 148, 2395-2404.
9. Romer, L. H., McLean, N. V., Yan, H. C., Daise, M., Sun, J., DeLisser, H. M. (1995) IFN-gamma and TNF-alpha induce redistribution of PECAM-1 (CD31) on human endothelial cells. J. Immunol. 154, 6582-6592.
10. Bogen, S., Pak, J., Garifallou, M., Deng, X., Muller, W. A. (1994) Monoclonal antibody to murine PECAM-1 (CD31) blocks acute inflammation in vivo. J. Exp. Med. 179, 1059-1064.
11. Vaporciyan, A. A., DeLisser, H. M., Yan, H. C., Mendiguren, I. I., Thom, S. R., Jones, M. L., Ward, P. A., Albelda, S. M. (1993) Involvement of platelet-endothelial cell adhesion molecule-1 in neutrophil recruitment in vivo. Science 262, 1580-1582.
12. Huang, A. J., Manning, J. E., Bandak, T. M., Ratau, M. C., Hanser, K. R., Silverstein, S. C. (1993) Endothelial cell cytosolic free calcium regulates neutrophil migration across monolayers of endothelial cells. J. Cell Biol. 120, 1371-1380.
13. Saito, H., Minamiya, Y., Kitamura, M., Saito, S., Enomoto, K., Terada, K., Ogawa, J. (1998) Endothelial myosin light chain kinase regulates neutrophil migration across human umbilical vein endothelial cell monolayer. J. Immunol. 161, 1533-1540.
14. Garcia, J. G. N., Verin, A. D., Herenyiova, M., English, D. (1998) Adherent neutrophils activate endothelial myosin light chain kinase: role in transendothelial migration. J. Appl. Physiol. 84, 1817-1821.
15. Burns, A. R., Walker, D. C., Brown, E. S., Thurmon, L. T., Bowden, R. B., Keese, C. R., Simon, S. I., Entman, M. L., Smith, C. W. (1997) Neutrophil transendothelial migration is independed of tight junctions and occurs preferentially at tricellular corner. J. Immunol. 159, 2893-2903.
16. Feng, D., Nagy, J. A., Pyne, K., Dvorak, H. F., Dvorak, A. M. (1998) Neutrophils emigrate from venules by transendothelial cell pathway in response to fMLP. J. Exp. Med. 187, 903-915.
17. Mitchison, T. J., Cramer, L. P. (1996) Actin-based cell motility and cell locomotion. Cell 84, 371-379.
18. Hixenbaugh, E. A., Goeckeler, Z. M., Papaiya, N. A., Wysolmerski, R. B., Silverstein, S. C., Huang, A. J. (1997) Stimulated neutrophils induce myosin light chain phosphorylation and isometric tension in endothelial cells. Am. J. Physiol. 273, H981-H988.
19. Kimura, K., Ito, M., Amano, M., Chihara, K., Fukata, Y., Nakafuku, M., Yamamori, B., Feng, J., Nakano, T., Okawa, K., Iwamatsu, A., Kaibuchi, K. (1996) Regulation of myosin phosphatase by Rho and Rho-associate kinase (Rho kinase). Science 273, 245-248.
20. Mackey, D. J. G., Hall, A. (1998) Rho GTPases. J. Biol. Chem. 273, 20685-20688.
21. Takai, Y., Sasaki, T., Matozaki, T. (2001) Small G proteins. Physiol. Rev. 81, 153-208.
22. Nobes, C. D., Hall, A. (1995) Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular filopodia. Cell 81, 53-62.
23. Ridley, A. J., Paterson, H. F., Johnston, C. L., Diekmann, D., Hall, A. (1992) The small GTP-binding protein rac regulates growing factor-induced membrane ruffling. Cell 70, 401-410.
24. Ridley, A. J., Hall, A. (1992) The small GTP-binding protein Rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors. Cell 70, 389-399.
25. Essler, M., Amano, M., Kruse, H., Kaibuchi, K., Weber, P. C., Aepfelbacher, M. (1998) Thrombin inactivates myosin light chain phosphatase via Rho and its target Rho kinase in human endothelial cells. J. Biol. Chem. 273, 21867-21874.
26. Kawano, Y., Fukata, Y., Oshiro, N., Antano, M., Nakamura, T., Ito, M., Matsumura, F., Inagaki, M., Kaibuchi, K. (1999) Phosphorylation of myosin-binding subunit (MBS) of myosin phosphatase by Rho-kinase. J. Cell Biol. 147, 1023-1037.
27. Amano, M., Ito, M., Kimura, K., Fukata, Y., Chihara, K., Takano, T., Matsuura, Y., Kaibuchi, K. (1996) Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase). J. Biol. Chem. 271, 20242-20249.
28. Nemoto, Y., Namba, T., Kozaki, S., Nammiya, S. (1991) Clostridium botulinum C3 ADP-ribosyltransferase gene. Cloning, sequencing, and expression of a functional protein in Escherichia coli. J. Biol. Chem. 266, 19312-19319.
29. Morii, N., Narumiya, S. (1995) Preparation of native and recombinant Clostridium botulinum C3 ADP-ribosyltransferase and identification of Rho proteins by ADP-ribosylation. Methods Enzymol. 256, 196-206.
30. Seike, A., Fujiwara, M., Narumiya, S. (1989) Asparagine residue in the rho gene product is the modification site for botulinum ADP-ribosyltransferase. J. Biol. Chem. 264, 8602-8605.
31. Maekawa, M., Ishizuka, T., Boku, S., Watanabe, N., Fujita, A., Iwamatsu, A., Obinata, T., Ohashi, K., Mizuno, K. Narumiya, S. (1999) Signaling from Rho to the actin cytoskeleton through protein kinase ROCK and LIM-kinase. Science 285, 895-898.
32. Uehata, M., Ishizuka, T., Satoh, H., Ono, T., Kawahara, T., Morishita, T., Tamakawa, H., Yamagami, K., Inui, J., Maekawa, M., Narumiya, S. (1997) Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension. Nature 389, 990-994.
33. Daniel, J. L., Sellers, J. R. (1992) Purification and characterization of platelet myosin. Methods Enzymol. 215, 78-80.
34. Huang, A. J., Furie, M. B., Nicholson, S. C., Fishbarg, J., Liebovitch, L. S., Silverstein, S. C. (1988) Effects of human neutrophil chemotaxis across human endothelial cell monolayers on the permeability of these monolayer to ions and macromolecules. J. Cell. Phyiol. 135, 355-366.
35. Del Mashio, A., Maillet, E., Maillet, F., Kazatchkine, M. D., Maclouf, J. (1989) Platelet-dependent induction and amplification of polymorphonuclear leukocyte lysosomal enzyme release. Br. J. Haematol. 72, 329-355.
36. Wysolmerski, R. B., Lagunoff, D. (1990) Involvement of myosin light-chain kinase in endothelial cell retraction. Proc. Natl. Acad. Sci. USA 87, 16-20.
37. Wysolmerski, R. B., Lagunoff. D. (1991) Regulation of permeabilized endothelial cell retraction by myosin phosphorylation. Am. J. Physiol. 261, C32-C40.
38. Hippenstiel, S., Tannert-Otto, S., Vollrath, N., Krull, M., Just, I., Aktories, K., Von Eichel-Streiber, C., Suttorp, N. (1997) Glucosylation of small GTP-binding Rho proteins disrupts endothelial barrier function. Am. J. Physiol. 272, L38-L43.
39. Carbajal, J. M., Gratrix, M. L., Yu, C. H., Schaeffer, R. C. (2000) ROCK mediates thrombin's endothelial barrier function. Am. J. Physiol. 279, C195-C204.
40. Cui, Y., English, D., Siddiqui, R. A., Herenyiova, M., Garcia, J. G. (1997) Activation of endothelial cell phospholipase D by migrating neutrophils. J. Investig. Med. 45, 388-393.
41. Goeckeler, Z. M., Wysolmerski, R. B. (1995) Myosin light chain kinase-regulated endothelial cell contraction: the relationship between isometric tension, actin polymerization, and myosin phosphorylation. J. Cell Biol. 130, 613-627.
42. Cooper, D., Lindberg, F. P., Gamble, J. R., Brown, E. J., Vadas, M. A. (1995) Transendothelial migration of neutrophils involves integrin-associated protein (CD47). Proc. Natl. Acad. Sci. USA 92, 3978-3982.