Defective NF-κB activation in virus-infected neuronal cells is restored by genetic complementation

Journal of NeuroVirology

Volumn 8, Issue 5, 2002, Pages 459-463

  Fang, Yu Yan ^a,c   Song, Zan Min ^a,c   Wu, Tao ^a,c   Raha R , Abhijit ^b   Kalvakolanu, Dhananjava V ^b   Dhib Jalbut, Suhayl ^a,c  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MARYLAND   (United States)

^c DEPARTMENT OF VETERANS AFFAIRS   (United States)

Author keywords

I B ; Interferon beta; Measles virus; Neuronal cell; NF B

Indexed keywords

BETA INTERFERON; COMPLEMENTARY DNA; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1; LIPOPOLYSACCHARIDE; TUMOR NECROSIS FACTOR ALPHA; NF KAPPAB INHIBITOR ALPHA; NF-KAPPAB INHIBITOR ALPHA;

ANIMAL CELL; ARTICLE; CYTOPLASM; DNA LIBRARY; GENE INDUCTION; GENETIC COMPLEMENTATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; MEASLES VIRUS; NERVE CELL; NERVE CELL CULTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; VIRUS INFECTION; CELL LINE; GENE LIBRARY; GLIA; METABOLISM; PHOSPHORYLATION; VIROLOGY;

ALPHAVIRUS; ANIMALIA; MEASLES VIRUS;

CELL LINE; GENE LIBRARY; GENETIC COMPLEMENTATION TEST; HUMANS; I-KAPPA B PROTEINS; INTERFERON-BETA; INTERLEUKIN-1; LIPOPOLYSACCHARIDES; MEASLES VIRUS; NEUROGLIA; NEURONS; NF-KAPPA B; PHOSPHORYLATION; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0036816669     PISSN: 13550284     EISSN: None     Source Type: Journal    
DOI: 10.1080/13550280260422776     Document Type: Article

References (20)

1. Dhib-Jalbut S, Johnson KP (1994). Measles virus diseases. In Handbook of virology. McKendall RR, Stroop WG (eds). Marcel Dekker: New York, pp. 539-554.
2. Dhib-Jalbut S, Xia J, Rangaviggula H, Fang YY, Lee T (1999). Failure of measles virus to activate nuclear factor-kappa B in neuronal cells: Implications on the immune response to viral infections in the central nervous system. J Immunol 162: 4024-4029.
3. Dhib-Jalbut SS, Cowan EP (1993). Direct evidence that interferon-beta mediates enhanced HLA-class I expression in measles virus-infected cells. J Immunol 151: 6248-6258.
4. Dhib-Jalbut SS, Xia Q, Drew PD, Swoveland PT (1995). Differential up-regulation of HLA class 1 molecules on neuronal and glial cell lines by virus infection correlates with differential induction of IFN-beta. J Immunol 155: 2096-2108.
5. Drupraz P, Cottet S, Hamburger F, Dolci W, Felley-Bosco E, Thorens B (2000). Dominant negative MyD88 proteins inhibit interleukin-1 beta/interferon-gamma-mediated induction of nuclear factor kappa B-dependent nitrite production and apoptosis in beta cells. J Biol Chem 275: 37672-37678.
6. Fang Y-Y, Song Z-M, Dhib-Jalbut S (2001). Mechanism of measles virus failure to activate NF-κB in neuronal cells. J Neuro Virol 7: 522-562.
7. Finco TS, Baldwin AS (1995). Mechanistic aspects of NF-kappa B regulation: The emerging role of phosphorylation and proteolysis. Immunity 3: 263-272.
8. Gogate N, Swoveland P, Yamabe T, Verma L, Woyciechowska J, Tarnowska-Dziduszko E, Dymecki J, Dhib-Jalbut S (1996). Major histocompatibility complex (MHC)-class I expression on neurons in subacute sclerosing panencephalitis (SSPE) and experimental subacute measles encephalitis (SME). J Neuropathol Exp Neurol 55: 435.
9. Hart RP, Liu C, Shadiack AM, McCormack RJ, Jonakait GM (1993). An mRNA homologous to interleukin-1 receptor type 1 is expressed in cultured rat sympathetic ganglia. J Neuroimmunol 44: 49.
10. Haskill S, Baldwin AS (1991). Characterization of an immediate-early gene induced in adherent monocytes that encodes IκB-like activity. Cell 65: 1281-1289.
11. Hiscott J, Kwon H, Genin P (2001). Hostile takeovers: viral appropriation of the NF-κB pathway. J Clin Invest 107: 143-151.
12. Joly E, Mucke L, Oldstone MBA (1991). Viral persistence in neurons explained by lack of major histocompatibility class I expression. Science 253: 1283-1285.
13. Li X, Commane M, Nie H, Hua X. Chatterjee-Kishore M, Wald D, Haag M, Start GR (2000). Act1, an NF-kappa B-activating protein. Proc Natl Acad Sci USA 97: 10489-10493.
14. Liebert UG, Linington C, ter Meulen V (1988). Induction of autoimmune reactions to myelin basic protein in measles virus encephalitis in Lewis rats. J Neuroimmunol 17: 103-118.
15. Nasuhara Y, Adcock IM, Catley M, Barnes PJ, Newton R (1999). Differential IkB kinase activation and IκBα degradation by interleukin-1b and tumor necrosis factor-a in human U937 monocytic cells. J Biol Chem 274: 19965-19972.
16. Ninomiya-Tsuji J, Kishimoto K, Hiyama A, Inoue J, Cao Z, Matsumoto K (1999). The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway. Nature 398: 252-256.
17. Ozes ON, Mayo LD, Gustin JA, Pfeffer SR, Pfeffer LM, Donner DB (1999). NF-κB activation by tumor necrosis factor requires the Akt serine-threonine kinase. Nature 401: 82-85.
18. Takaesu G, Ninomiya-Tsuji J, Kishida S, Li X, Stark GR, Matsumoto K (2001). Interleukin-1 (IL-1) receptor-associated kinase leads to activation of TAK1 by inducing TAB2 translocation in the IL-1 signaling pathway. Mol Cell Biol 21: 2475-2484.
19. Ting AT, Pimentel-Muinos FX, Seed B (1996). RIP mediates tumor necrosis factor receptor 1 activation of NF-kappa B but not Fas/APO-1-initiated apoptosis. EMBO J 15: 6189-6196.
20. Yamaoka S, Courtois G, Bessia C, Whiteside ST, Weil R, Agou F, Kirk HE, Kay RJ, Israel A (1998). Complementation cloning of NEMO, a component of the IκB kinase complex essential for NF-κB activation. Cell 93: 1231-1240.