Expression patterns of cytokines and chemokines genes in human hepatoma cells

Yonsei Medical Journal

Volumn 43, Issue 5, 2002, Pages 657-664

  Shin, Eui Cheol ^a   Choi, Youn Hee ^a   Kim, Ji Su ^a   Kim, Se Jong ^b   Park, Jeon Han ^b  

^a Yonsei University   (South Korea)

^b Yonsei University College of Medicine   (South Korea)

Author keywords

Chemokine; Cytokine; Fas; Hepatoma; Interleukin 8; MCP 1; TGF

Indexed keywords

CHEMOKINE; CYTOKINE; FAS LIGAND; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 8; LYMPHOTACTIN; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; RANTES; TRANSFORMING GROWTH FACTOR BETA2; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CANCER CELL; CELL LINE; CONTROLLED STUDY; GENE EXPRESSION; GENE OVEREXPRESSION; HEPATITIS B VIRUS; HUMAN; HUMAN CELL; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; RIBONUCLEASE PROTECTION ASSAY;

EID: 0036806619     PISSN: 05135796     EISSN: None     Source Type: Journal    
DOI: 10.3349/ymj.2002.43.5.657     Document Type: Article

References (34)

1. Nicola NA. Guidebook to cytokines and their receptors. 1st ed. New York (NY): Oxford University Press; 1994.
2. Baggiolini M, Dewald B, Moser B. Human chemokines: an update. Ann Rev Immunol 1997;15:675-705.
3. Stonans I, Stonane E, Rubwurm S, Deigner HP, Bohm KJ, Wiederhold M, et al. HepG2 human hepatoma cells express multiple cytokine genes. Cytokine 1999;11:151-6.
4. Yoong KF, Afford SC, Jones R, Aujla P, Qin S, Price K, et al. Expression and function of CXC and CC chemokines in human malignant liver tumors: a role for human monokine induced by γ-interferon in lymphocyte recruitment to hepatocellular carcinoma. Hepatology 1999;30:100-11.
5. Abreu-Martin MT, Vidrich A, Lynch DH, Targan SR. Divergent induction of apoptosis and IL-8 secretion in HT-29 cells in response to TNF-α and ligation of Fas antigen. J Immunol 1995;155:4147-54.
6. Sekine C, Yagita H, Kobata T, Hasunuma T, Nishioka K, Okumura K. Fas-mediated stimulation induces IL-8 secretion by rheumatoid arthritis synoviocytes independently of CDD32-mediated apoptosis. Biochem Biophys Res Commun 1996;228:14-20.
7. Hagimoto N, Kuwano K, Kawasaki M, Yoshimi M, Kaneko Y, Kunitake R, et al. Induction of interleukin-8 secretion and apoptosis in bronchiolar epithelial cells by Fas ligation. Am J Respir Cell Mol Biol 1999;21:436-45.
8. Saas P, Boucraut J, Quiquerez AL, Schnuriger V, Perrin G, Desplat-Jego S, et al. CD95 (Fas/Apo-1) as a receptor governing astrocyte apoptotic or inflammatory responses: a key role in brain inflammation? J Immunol 1999;162:2326-33.
9. Lee SJ, Zhou T, Choi C, Wang Z, Benveniste EN. Differential regulation and function of Fas expression on glial cells. J Immunol 2000;164:1277-85.
10. Choi C, Xu X, Oh JW, Lee SJ, Gillespie GY, Park H, et al. Fas-induced expression of chemokines in human glioma cells: involvement of extracellular signal-regulated kinase 1/2 and p38 mitogen-activated protein kinase. Cancer Res 2001;61:3084-91.
11. Sells MA, Chen ML, Acs G. Production of hepatitis B virus particles in Hep G2 cells transfected with cloned hepatitis B virus DNA. Proc Natl Acad Sci USA 1987; 84:1005-8.
12. Park JG, Lee JH, Kang MS, Park KJ, Jeon YM, Lee HJ, et al. Characterization of cell lines established from human hepatocellular carcinoma. Int J Cancer 1995;62: 276-82.
13. Shin EC, Shin WC, Choi Y, Kim H, Park JH, Kim SJ. Effect of interferon-γ on the susceptibility to Fas (CD95/APO-1)-mediated cell death in human hepatoma cells. Cancer Immunol Immunother 2001;50:23-30.
14. Yano H, Fukuda K, Haramaki M, Momosaki S, Ogasawara S, Higaki K, et al. Expression of Fas and anti-Fas-mediated apoptosis in human hepatocellular carcinoma cell lines. J Hepatol 1996;25:454-64.
15. Yoo YD, Ueda H, Park K, Flanders KC, Lee YI, Jay G, et al. Regulation of transforming growth factor-β1 expression by the hepatitis B virus (HBV) X transactivator. Role in HBV pathogenesis. J Clin Invest 1996;97: 388-95.
16. Mahe Y, Mukaida N, Kuno K, Akiyama M, Ikeda N, Matsushima K, et al. Hepatitis B virus X protein transactivates human interleukin-8 gene through acting on nuclear factor κ B and CCAAT/enhancer-binding protein-like cis-elements. J Biol Chem 1991;266:13759-63.
17. Lee Y, Park US, Choi I, Yoon SK, Park YM, Lee YI. Human interleukin 6 gene is activated by hepatitis B virus-X protein in human hepatoma cells. Clin Cancer Res 1998;4:1711-7.
18. Amaro RG, Monzon CG, Garcia-Buey L, Moreno-Otero R, Alonso JL, Yague E, et al. Induction of tumor necrosis factor α production by human hepatocytes in chronic viral hepatitis. J Exp Med 1994;179:841-8.
19. Delpuech O, Trabut JB, Carnot F, Feuillard J, Brechot C, Kremsdorf D. Identification, using cDNA microarray analysis, of distinct gene expression profiles associated with pathological and virological features of hepatocellular carcinoma. Oncogene 2002;21:2926-37.
20. Kim HG, Chung YH, Song BC, Kim J, Yang SH, Lee YS, et al. Expression of transforming growth factor beta-1 in chronic hepatitis and hepatocellular carcinoma associated with hepatitis C virus infection. Korean J Intern Med 2000;15:165-70.
21. Miyamoto M, Shimizu Y, Okada K, Kashii Y, Higuchi K, Watanabe A. Effect of interleukin-8 on production of tumor-associated substances and autocrine growth of human liver and pancreatic cancer cells. Cancer Immunol Immunother 1998;47:47-57.
22. Desbaillets I, Diserens A, de Tribolet N, Hamou M, Van Meir EG. Upregulation of interleukin 8 by oxygen-deprived cells in glioblastoma suggests a role in leukocyte activation, chemotaxis, and angiogenesis. J Exp Med 1997;186:1201-12.
23. Arenberg DA, Kunkel SL, Polverini PJ, Glass M, Burdick MD, Strieter RM. Inhibition of interleukin-8 reduces tumorigenesis of human non-small cell lung cancer in SCID mice. J Clin Invest 1996;97:2792-802.
24. Singh RK, Gutman M, Radinsky R, Bucana CD, Fidler IJ. Expression of interleukin-8 correlates with the metastatic potential of human melanoma cells in nude mice. Cancer Res 1994;54:3242-7.
25. Shima Y, Nakao K, Nakashima T, Kawasami A, Nakata K, Hamasaki K, et al. Activation of caspase-8 in transforming growth factor-β-induced apoptosis of human hepatoma cells. Hepatology 1999;30:1215-22.
26. Furuta K, Misao S, Takahashi K, Tagaya T, Fukuzawa Y, Ishikawa T, et al. Gene mutation of transforming growth factor beta1 type II receptor in hepatocellular carcinoma. Int J Cancer 1999;81:851-3.
27. Yakicier MC, Irmak MB, Romano A, Kew M, Ozturk M. Smad2 and Smad4 gene mutations in hepatocellular carcinoma. Oncogene 1999;18:4879-83.
28. Chen RH, Chang MC, Su YH, Tsai YT, Kuo ML. Interleukin-6 inhibits transforming growth factor-β-induced apoptosis through the phosphatidyl inositol 3-kinase/Akt and signal transducers and activators of transcription 3 pathways. J Biol Chem 1999;274:23013-9.
29. Kang SM, Schneider DB, Lin Z, Hanahan D, Dichek DA, Stock PG, et al. Fas ligand expression in islets of Langerhans does not confer immune privilege and instead targets them for rapid destruction. Nat Med 1997;3:738-43.
30. Schaub FJ, Han DKM, Liles WC, Adams LD, Coats SA, Ramachandran RK, et al. Fas/FADD-mediated activation of a specific program of inflammatory gene expression in vascular smooth muscle cells. Nat Med 2000;6:790-6.
31. Shin E-C, Shin J-S, Park JH, Kim J-J, Kim H, Kim SJ. Expression of Fas-related genes in human hepatocellular carcinomas. Cancer Lett 1998;134:155-62.
32. Luster AD, Leder P. IP-10, a -C-X-C- chemokine, elicits a potent thymus-dependent antitumor response in vivo. J Exp Med 1993;178:1057-65.
33. Sgadari C, Angiolillo AL, Cherney BW, Pike SE, Farber JM, Koniaris LG, et al. Interferon-inducible protein-10 identified as a mediator of tumor necrosis in vivo. Proc Natl Acad Sci USA 1996;93:13791-6.
34. Tamaru M, Nishioji K, Kobatashi Y, Watanabe Y, Itoh Y, Okanoue T, et al. Liver-infiltrating T lymphocytes are attracted selectively by IFN-inducible protein-10. Cytokine 2000;12:299-308.