Expression of calreticulin P-domain results in impairment of secretory pathway in Leishmania donovani and reduced parasite survival in macrophages

International Journal for Parasitology

Volumn 32, Issue 11, 2002, Pages 1423-1434

  Debrabant, Alain ^a   Lee, Nancy ^a   Pogue, Gregory P ^b   Dwyer, Dennis M ^c   Nakhasi, Hira L ^a  

^a Building 29   (United States)

^b Large Scale Biology Corporation   (United States)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Calreticulin; Chaperone; Folding; Leishmania; Macrophage; Secretion

Indexed keywords

ACID PHOSPHATASE; CALRETICULIN; CALRETICULIN P; CHAPERONE; SECRETORY PROTEIN; UNCLASSIFIED DRUG;

LEISHMANIASIS; PARASITOLOGY; SECRETION;

ARTICLE; CELL STRUCTURE; CELL TRANSPORT; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; HUMAN; HUMAN CELL; LEISHMANIA DONOVANI; MACROPHAGE; NONHUMAN; PARASITE SURVIVAL; PARASITE VIRULENCE; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN TARGETING; TRYPANOSOMA;

ACID PHOSPHATASE; ANIMALS; BLOTTING, WESTERN; CALRETICULIN; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GENE EXPRESSION; GENES, PROTOZOAN; HUMANS; LEISHMANIA DONOVANI; MACROPHAGES; PLASMIDS; PRECIPITIN TESTS; PROTEIN STRUCTURE, TERTIARY; PROTOZOAN PROTEINS; TRANSFECTION; VIRULENCE;

EUKARYOTA; INSECTA; LEISHMANIA DONOVANI; MAMMALIA;

EID: 0036804357     PISSN: 00207519     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0020-7519(02)00134-0     Document Type: Article

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