The effect of cyclooxygenase-2 inhibitors on spinal fusion

Journal of Bone and Joint Surgery

Volumn 84, Issue 10, 2002, Pages 1763-1768

  Long, John ^a   Lewis, Stephen ^a   Kuklo, Timothy ^a   Zhu, Yong ^a   Riew, K Daniel ^a  

^a BARNES JEWISH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELECOXIB; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2 INHIBITOR; INDOMETACIN; NONSTEROID ANTIINFLAMMATORY AGENT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTHRODESIS; ARTICLE; BONE GRAFT; CONTROLLED STUDY; DRUG CHOICE; DRUG EFFECT; DRUG MECHANISM; HISTOPATHOLOGY; ILIAC CREST; LUMBAR SPINE; NONHUMAN; PERIOPERATIVE PERIOD; POSTOPERATIVE CARE; PRIORITY JOURNAL; RABBIT; SCORING SYSTEM; SPINE FUSION; SPINE SURGERY; WOUND HEALING;

EID: 0036797840     PISSN: 00219355     EISSN: None     Source Type: Journal    
DOI: 10.2106/00004623-200210000-00004     Document Type: Article

References (12)

1. Dimar JR 2nd, Ante WA, Zhang YP, Glassman SD. The effects of nonsteroidal anti-inflammatory drugs on posterior spinal fusions in the rat. Spine. 1996;21:1870-6.
2. Glassman SD, Rose SM, Dimar JR, Puno RM, Campbell MJ, Johnson JR. The effect of postoperative nonsteroidal anti-inflammatory drug administration on spinal fusion. Spine. 1998;23:834-8.
3. Keller J, Bunger C, Andreassen TT, Bak B, Lucht U. Bone repair inhibited by indomethacin. Effects on bone metabolism and strength of rabbit osteotomies. Acta Orthop Scand. 1987;58:379-83.
4. Bo J, Sudmann E, Marton PF. Effect of indomethacin on fracture healing in rats. Acta Orthop Scand. 1976;47:588-99.
5. Hawkey CJ. COX-2 inhibitors. Lancet. 1999;353:307-14.
6. Smith CJ, Zhang Y, Koboldt CM, Muhammad J, Zwelfel BS, Shaffer A, Talley JJ, Masferrer JL, Seibert K, Isakson PC. Pharmacological analysis of cyclooxygenase-1 in inflammation. Proc Natl Acad Sci U S A. 1998;95:13313-8.
7. Boden SD, Schimandle JH, Hutton WC. 1995 Volvo Award in basic sciences. The use of an osteoinductive growth factor for lumbar spinal fusion. Part II: Study of dose, carrier, and species. Spine. 1995;20:2633-44.
8. Timm KI, Picton JS, Tylman B. Surface area to volume relationships of snakes support the use of allometric scaling for calculating dosages of pharmaceuticals. Lab Anim Sci. 1994;44:60-2.
9. Tornkvist H, Lindholm TS, Netz P, Stromberg L, Lindholm TC. Effect of ibuprofen and indomethacin on bone metabolism reflected in bone strength. Clin Orthop. 1984;187:255-9.
10. Emery SE, Brazinski MS, Koka A, Bensusan JS, Stevenson S. The biological and biomechanical effects of irradiation on anterior spinal bone grafts in a canine model. J Bone Joint Surg Am. 1994;76:540-8.
11. Glazer PA, Heilmann MR, Lotz JC, Bradford DS. Use of ultrasound in spinal arthrodesis. A rabbit model. Spine. 1998;23:1142-8.
12. Boden SD, Schimandel JH, Hutton WC. An experimental lumbar intertransverse process spinal fusion model. Radiographic, histologic, and biomechanical healing characteristics. Spine. 1995;20:412-20.