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Volumn 103, Issue 4, 2002, Pages 397-402

The Trp64Arg β3-adrenergic receptor amino acid variant confers increased sensitivity to the pressor effects of noradrenaline in Sardinian subjects

Author keywords

Metabolic syndrome; Noradrenaline; Triacylglycerol; Type II diabetes

Indexed keywords

ARGININE; BETA 3 ADRENERGIC RECEPTOR; FATTY ACID; GELATIN; GLUCOSE; NORADRENALIN; TRIACYLGLYCEROL; TRYPTOPHAN; VASOCONSTRICTOR AGENT;

EID: 0036796752     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/cs1030397     Document Type: Article
Times cited : (16)

References (35)
  • 1
    • 0014194186 scopus 로고
    • Differentiation of receptor systems activated by sympathomimetic amines
    • Lands, A. M., Arnold, A., McAuliff, J. P., Luduena, F. P. and Brown, G. (1967) Differentiation of receptor systems activated by sympathomimetic amines. Nature (London) 214, 597-598
    • (1967) Nature (London) , vol.214 , pp. 597-598
    • Lands, A.M.1    Arnold, A.2    McAuliff, J.P.3    Luduena, F.P.4    Brown, G.5
  • 2
    • 0028183015 scopus 로고
    • International union of pharmacology nomenclature of adrenoceptors
    • Bylund, D. V., Einkenberg, D. C., Hieble, J. P. et al. (1994) International union of pharmacology nomenclature of adrenoceptors. Pharmacol. Rev. 46, 121-136
    • (1994) Pharmacol. Rev. , vol.46 , pp. 121-136
    • Bylund, D.V.1    Einkenberg, D.C.2    Hieble, J.P.3
  • 3
    • 0029363420 scopus 로고
    • Determination of beta-3 adrenergic receptor mediated lipolysis in human fat cells
    • Hoffstedt, J., Shimizu, M., Sjosted, S. and Lonnqvist, F. (1995) Determination of beta-3 adrenergic receptor mediated lipolysis in human fat cells. Obes. Res. 3, 447-457
    • (1995) Obes. Res. , vol.3 , pp. 447-457
    • Hoffstedt, J.1    Shimizu, M.2    Sjosted, S.3    Lonnqvist, F.4
  • 6
    • 0028128081 scopus 로고
    • Peripheral vascular effects of beta-3 adrenergic receptor stimulation in conscious dogs
    • Shen, Y. T., Zhang, H. and Vatner, F. (1994) Peripheral vascular effects of beta-3 adrenergic receptor stimulation in conscious dogs. J. Pharmacol. Exp. Ther. 268, 466-473
    • (1994) J. Pharmacol. Exp. Ther. , vol.268 , pp. 466-473
    • Shen, Y.T.1    Zhang, H.2    Vatner, F.3
  • 9
    • 0029084088 scopus 로고
    • Time of onset of non-insulin-dependent diabetes mellitus and genetic variation in the beta 3-adrenergic-receptor gene
    • Walston, J., Silver, K., Bogardus, C. et al. (1995) Time of onset of non-insulin-dependent diabetes mellitus and genetic variation in the beta 3-adrenergic-receptor gene. N. Engl. J. Med. 333, 343-347
    • (1995) N. Engl. J. Med. , vol.333 , pp. 343-347
    • Walston, J.1    Silver, K.2    Bogardus, C.3
  • 11
    • 0032975269 scopus 로고    scopus 로고
    • Association of Trp64Arg Beta3-adrenergic-receptor gene polymorphism with essential hypertension in the Sardinian population
    • Tonolo, G., Melis, M. G., Secchi, G. et al. (1999) Association of Trp64Arg Beta3-adrenergic-receptor gene polymorphism with essential hypertension in the Sardinian population. J. Hypertens. 17, 33-38
    • (1999) J. Hypertens. , vol.17 , pp. 33-38
    • Tonolo, G.1    Melis, M.G.2    Secchi, G.3
  • 12
    • 18144439868 scopus 로고    scopus 로고
    • Association of the Trp64Arg mutation of the Beta3-adrenergic-receptor with fatty liver and mild glucose intolerance in Japanese subjects
    • Shima, Y., Tsukada, T., Nakanishi, K. and Ohta, H. (1998) Association of the Trp64Arg mutation of the Beta3-adrenergic-receptor with fatty liver and mild glucose intolerance in Japanese subjects. Clin. Chim. Acta 274, 167-176
    • (1998) Clin. Chim. Acta , vol.274 , pp. 167-176
    • Shima, Y.1    Tsukada, T.2    Nakanishi, K.3    Ohta, H.4
  • 13
    • 15444347628 scopus 로고    scopus 로고
    • The Trp64Arg polymorphism of the Beta3-adrenergic-receptor gene is not associated with obesity or type 2 diabetes mellitus in a large population-based Caucasian cohort
    • Buetter, R., Schaffler, A. and Arndt, H. (1998) The Trp64Arg polymorphism of the Beta3-adrenergic-receptor gene is not associated with obesity or type 2 diabetes mellitus in a large population-based Caucasian cohort. J. Clin. Endocrinol. Metab. 83, 2892-2897
    • (1998) J. Clin. Endocrinol. Metab. , vol.83 , pp. 2892-2897
    • Buetter, R.1    Schaffler, A.2    Arndt, H.3
  • 15
    • 7844236387 scopus 로고    scopus 로고
    • A resource for studying gene-environment interrelations in type 2 diabetes
    • Tonolo, G., Ciccarese, M., Melis, M. G. et al. (1998) A resource for studying gene-environment interrelations in type 2 diabetes. Diabetes Nutr. Metab. 11, 157-168
    • (1998) Diabetes Nutr. Metab. , vol.11 , pp. 157-168
    • Tonolo, G.1    Ciccarese, M.2    Melis, M.G.3
  • 16
    • 0022481703 scopus 로고
    • Effect of low dose adrenaline and noradrenaline infusions on airway calibre in asthmatic patients
    • Berkin, K. E., Inglis, G. C., Ball, S. G. and Thomson, N. C. (1986) Effect of low dose adrenaline and noradrenaline infusions on airway calibre in asthmatic patients. Clin. Sci. 70, 347-352
    • (1986) Clin. Sci. , vol.70 , pp. 347-352
    • Berkin, K.E.1    Inglis, G.C.2    Ball, S.G.3    Thomson, N.C.4
  • 17
    • 0029188466 scopus 로고
    • Cyclical variation of plasma lipids, apolipoproteins and lipoprotein(a) during menstrual cycle in normal women
    • Tonolo, G., Ciccarese, M., Brizzi, P. et al. (1995) Cyclical variation of plasma lipids, apolipoproteins and lipoprotein(a) during menstrual cycle in normal women. Am. J. Physiol. 269, E1101-E1105
    • (1995) Am. J. Physiol. , vol.269
    • Tonolo, G.1    Ciccarese, M.2    Brizzi, P.3
  • 18
    • 0015348189 scopus 로고
    • Estimate of the concentration of low density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge
    • Friedewald, W. T., Levy, R. I. and Fredrickson, S. (1972) Estimate of the concentration of low density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin. Chem. 18, 499-504
    • (1972) Clin. Chem. , vol.18 , pp. 499-504
    • Friedewald, W.T.1    Levy, R.I.2    Fredrickson, S.3
  • 19
    • 0027716856 scopus 로고
    • Adrenoceptor subtypes mediating catecholamine-induced thermogenesis in man
    • Blaak, E. E., Saris, W. H. M. and Van Baak, M. A. (1993) Adrenoceptor subtypes mediating catecholamine-induced thermogenesis in man. Int. J. Obes. 17, S78-S81
    • (1993) Int. J. Obes. , vol.17
    • Blaak, E.E.1    Saris, W.H.M.2    Van Baak, M.A.3
  • 20
    • 0030828826 scopus 로고    scopus 로고
    • Preliminary data on a wide genome search in NIDDM siblings; the NIDDM1 locus on chromosome 2 is not linked to NIDDM in the Sardinian population
    • Ciccarese, M., Tonolo, G., Delin, I. et al. (1997) Preliminary data on a wide genome search in NIDDM siblings; the NIDDM1 locus on chromosome 2 is not linked to NIDDM in the Sardinian population. Diabetologia 14, 1366-1367
    • (1997) Diabetologia , vol.14 , pp. 1366-1367
    • Ciccarese, M.1    Tonolo, G.2    Delin, I.3
  • 21
    • 8044222127 scopus 로고    scopus 로고
    • Physiological and genetic characterization of the Gly40Ser mutation in the glucagon receptor gene in the Sardinian population
    • Tonolo, G., Melis, M. G., Ciccarese, M. et al. (1997) Physiological and genetic characterization of the Gly40Ser mutation in the glucagon receptor gene in the Sardinian population. Diabetologia 40, 89-94
    • (1997) Diabetologia , vol.40 , pp. 89-94
    • Tonolo, G.1    Melis, M.G.2    Ciccarese, M.3
  • 22
    • 0030008290 scopus 로고    scopus 로고
    • Agonist and antagonist properties of beta3-adrenoceptors in human omental and mouse 3T3-L1 adipocytes
    • Shimizu, M., Blaak, E. E., Lonnqvist, F., Gafvels, M. E. and Arner, P. (1996) Agonist and antagonist properties of beta3-adrenoceptors in human omental and mouse 3T3-L1 adipocytes. Pharmacol. Toxicol. 78, 254-263
    • (1996) Pharmacol. Toxicol. , vol.78 , pp. 254-263
    • Shimizu, M.1    Blaak, E.E.2    Lonnqvist, F.3    Gafvels, M.E.4    Arner, P.5
  • 23
    • 0029905523 scopus 로고    scopus 로고
    • Phenotypic characterization of the Trp64Arg polymorphism in the beta 3-adrenergic receptor gene in normal weight and obese subjects
    • Li, L. S., Lonnqvist, F., Luthman, H. and Arner, P. (1996) Phenotypic characterization of the Trp64Arg polymorphism in the beta 3-adrenergic receptor gene in normal weight and obese subjects. Diabetologia 39, 857-860
    • (1996) Diabetologia , vol.39 , pp. 857-860
    • Li, L.S.1    Lonnqvist, F.2    Luthman, H.3    Arner, P.4
  • 25
    • 0027967031 scopus 로고
    • β-adrenergic control of lipolysis in primate white fat cells: A comparative study in non primate mammals
    • Bousquet-Mèlou, A., Galitzky, J., Carpènè, C., Lafontan, M. and Berlan, M. (1994) β-adrenergic control of lipolysis in primate white fat cells: a comparative study in non primate mammals. Am. J. Physiol. 267, R115-R123
    • (1994) Am. J. Physiol. , vol.267
    • Bousquet-Mèlou, A.1    Galitzky, J.2    Carpènè, C.3    Lafontan, M.4    Berlan, M.5
  • 26
    • 0028988313 scopus 로고
    • Regulation of beta 3-adrenoceptor expression in white fat cells
    • Langin, D., Tavernier, G. and Lafontan, M. (1995) Regulation of beta 3-adrenoceptor expression in white fat cells. Fund. Clin. Pharmacol. 9, 97-106
    • (1995) Fund. Clin. Pharmacol. , vol.9 , pp. 97-106
    • Langin, D.1    Tavernier, G.2    Lafontan, M.3
  • 27
    • 0032764779 scopus 로고    scopus 로고
    • Differential regulation of functional responses by β-adrenergic receptor subtypes in brown adipocytes
    • Chaudhry, A. and Granneman, J. G. (1999) Differential regulation of functional responses by β-adrenergic receptor subtypes in brown adipocytes. Am. J. Physiol. Regul. Integr. Comp. Physiol. 277, R147-R153
    • (1999) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.277
    • Chaudhry, A.1    Granneman, J.G.2
  • 28
    • 0034905890 scopus 로고    scopus 로고
    • Impaired non-esterified fatty acid suppression is associated with endothelial dysfunction in insulin resistant subjects
    • Balletshofer, B. M., Ritting, K., Volk, A. et al. (2001) Impaired non-esterified fatty acid suppression is associated with endothelial dysfunction in insulin resistant subjects. Horm. Metab. Res. 33, 428-431
    • (2001) Horm. Metab. Res. , vol.33 , pp. 428-431
    • Balletshofer, B.M.1    Ritting, K.2    Volk, A.3
  • 29
    • 0035318286 scopus 로고    scopus 로고
    • Nonesterified fatty acids in blood pressure control and cardiovascular complications
    • Egan, B. M., Greene, E. L. and Goodfriend, T. L. (2001) Nonesterified fatty acids in blood pressure control and cardiovascular complications. Curr. Hypertens. Rep. 3, 107-116
    • (2001) Curr. Hypertens. Rep. , vol.3 , pp. 107-116
    • Egan, B.M.1    Greene, E.L.2    Goodfriend, T.L.3
  • 30
    • 0030921893 scopus 로고    scopus 로고
    • Elevated circulating free fatty acid levels impair endothelium-dependent vasodilatation
    • Steinberg, H. O., Tarshoby, M., Monstrel, R. et al. (1997) Elevated circulating free fatty acid levels impair endothelium-dependent vasodilatation. J. Clin. Invest. 100, 1230-1239
    • (1997) J. Clin. Invest. , vol.100 , pp. 1230-1239
    • Steinberg, H.O.1    Tarshoby, M.2    Monstrel, R.3
  • 31
    • 0033815878 scopus 로고    scopus 로고
    • The impairment in endothelial function induced by non-esterified fatty acids can be reversed by insulin
    • Lind, L., Fugmann, A., Branth, S. et al. (2000) The impairment in endothelial function induced by non-esterified fatty acids can be reversed by insulin. Clin. Sci. 99, 169-174
    • (2000) Clin. Sci. , vol.99 , pp. 169-174
    • Lind, L.1    Fugmann, A.2    Branth, S.3
  • 32
    • 0034744185 scopus 로고    scopus 로고
    • Common variants in the beta 2 (Gln27Glu) and beta 3 (Trp64Arg) adrenoceptor genes are associated with elevated serum NEFA concentrations and type II diabetes
    • Carlsson, M., Orho-Melander, M., Hedenbro, J. and Groop, L. C. (2001) Common variants in the beta 2 (Gln27Glu) and beta 3 (Trp64Arg) adrenoceptor genes are associated with elevated serum NEFA concentrations and type II diabetes. Diabetologia 44, 629-636
    • (2001) Diabetologia , vol.44 , pp. 629-636
    • Carlsson, M.1    Orho-Melander, M.2    Hedenbro, J.3    Groop, L.C.4
  • 33
    • 0029741063 scopus 로고    scopus 로고
    • The future of genetic studies of complex human disease
    • Risch, N. and Merikangas, K. (1996) The future of genetic studies of complex human disease. Science 273, 1516-1517
    • (1996) Science , vol.273 , pp. 1516-1517
    • Risch, N.1    Merikangas, K.2
  • 34
    • 0030000431 scopus 로고    scopus 로고
    • Genetic analysis of Sardinia: I. Data on 12 polymorphisms in 21 linguistic domains
    • Cappello, N., Rendine, S., Griffo, R. et al. (1996) Genetic analysis of Sardinia: I. Data on 12 polymorphisms in 21 linguistic domains. Ann. Hum. Genet. 60, 125-141
    • (1996) Ann. Hum. Genet. , vol.60 , pp. 125-141
    • Cappello, N.1    Rendine, S.2    Griffo, R.3
  • 35
    • 0027919803 scopus 로고
    • Who are the Europeans?
    • Piazza, A. (1993) Who are the Europeans? Science 260, 1767-1769
    • (1993) Science , vol.260 , pp. 1767-1769
    • Piazza, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.