Parathyroid hormone-related peptide expression in cartilaginous tumors

Clinical Orthopaedics and Related Research

Volumn 403, Issue , 2002, Pages 198-204

  Pateder, Dhruv B ^a   Gish, Michael W ^a   O'Keefe, Regis J ^a   Hicks, David G ^a   Teot, Lisa A ^a   Rosier, Randy N ^a  

^a UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PARATHYROID HORMONE RELATED PROTEIN; PARATHYROID HORMONE; PEPTIDE HORMONE; PROTEIN; PTHLH PROTEIN, HUMAN;

ARTICLE; CANCER CLASSIFICATION; CANCER DIAGNOSIS; CANCER GRADING; CARTILAGE TUMOR; CELL PROLIFERATION; CHONDROSARCOMA; CONTROLLED STUDY; CORRELATION ANALYSIS; ENCHONDROMA; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; OSTEOCHONDROMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR GROWTH; CONNECTIVE TISSUE TUMOR; HOSPITALIZATION; IMMUNOLOGY; OSTEOBLAST; OSTEOCLAST; PATHOLOGY; STAINING;

HUMANS; NEOPLASMS, CONNECTIVE TISSUE; OSTEOBLASTS; OSTEOCLASTS; PARATHYROID HORMONE; PARATHYROID HORMONE-RELATED PROTEIN; PEPTIDE HORMONES; PROTEINS; SEVERITY OF ILLNESS INDEX; STAINING AND LABELING;

EID: 0036794758     PISSN: 0009921X     EISSN: 15281132     Source Type: Journal    
DOI: 10.1097/00003086-200210000-00029     Document Type: Article

References (25)

1. Aigner T, Loos S, Muller S, et al: Cell differentiation and matrix gene expression in mesenchymal chondrosarcomas. Am J Pathol 156:1327-1335. 2000.
2. Alipov GK, Ito M, Nakashima M, et al: Expression of parathyroid hormone-related peptide (PTHrP) in gastric tumours. J Pathol 182:174-179, 1997.
3. Amizuka N, Warshawsky H, Henderson J, Goltzman D, Karaplis A: Parathyroid hormone-related peptide-depleted mice show abnormal epiphyseal cartilage development and altered endochondral bone formation. J Cell Biol 126:1611-1623, 1994.
4. Amling M, Neff L, Tanaka S, et al: Bcl-2 lies down-stream of parathyroid hormone-related peptide in a signaling pathway that regulates chondrocyte maturation during skeletal development. J Cell Biol 136:205-213, 1997.
5. Crabb ID, Hughes SS, Hicks DG, et al: Nonradioactive in situ hybridization using digoxigenin labeled nucleotides: Applications to musculoskeletal tissues. Am J Pathol 141:579-589, 1992.
6. Guenther HL, Hofstetter W, Mosely JM, et al: Evidence for the synthesis of parathyroid hormone-related protein (PTHrP) by nontransfonned clonal rat osteoblastic cells in vitro. Bone 16:341-347, 1995.
7. Guise TA, Yin JJ, Taylor SD, et al: Evidence for a causal role of parathyroid hormone-related protein in the pathogenesis of human breast cancer-mediated osteolysis. J Clin Invest 98:1544-1549, 1996.
8. Halbert AR, Harrison WR, Hicks MJ, Davino N, Cooley LD: Cytogenetic analysis of a scapular chondromyxoid fibroma. Cancer Genet Cytogenet 104:52-56, 1998.
9. Hopyan S, Wunder JS, Bell RS, Andrulis IL, Alman BA: Expression of the indian hedgehog pathway in chondrosarcoma. Trans Orthop Res Soc 24:430, 1990.
10. Hsu S, Raine L, Fanger H: Use of avidin-biotin-peroxidase complex in immunoperoxidase techniques. J Histochem Cytochem 29:577-580, 1981.
11. Jüppner H, Abou-Samra AB, Freeman M, et al: A G protein-linked receptor for parathyroid hormone and parathyroid hormone-related peptide. Science 254:1024-1026, 1991.
12. Karaplis A, Luz A, Glowacki J, et al: Lethal skeletal dysplasia from targeted disruption of the parathyroid hormone-related peptide gene. Genes Dev 8:277-289, 1994.
13. Kartsogiannis V, Udagawa N, Ng KW, et al: Localization of parathyroid hormone-related protein in osteoclasts by in situ hybridization and immunohistochemistry. Bone 22:189-194, 1998.
14. Kukreja SC, Shevrin DH, Wimbiscus SA, et al: Antibodies to parathyroid hormone-related protein lowers serum calcium in athymic mouse models of malignancy-associated hypercalcemia due to human tumors. J Clin Invest 82:1798-1802, 1988.
15. Loveys LS, Gelb D, Hurwitz SR, Puzas JE, Rosier RN: Effects of parathyroid hormone-related peptide on chick growth plate chondrocytes. J Orthop Res 11:884-891, 1993.
16. Mankin HJ, Cantley KP, Lippiello L, Schiller AL, Campbell CJ: The biology of human chondrosarcoma: I. Description of the cases, grading, and biochemical analyses. J Bone Joint Surg 62A:160-176, 1980.
17. Ohmori M. Nagai M, Fujita M, et al: A novel mature B-cell line (DOBIL-6) producing both parathyroid hormone-related protein and interleukin-6 from a myeloma patient presenting with hypercalcaemia. Br J Haematol 101:688-693, 1998.
18. Pateder DB, Rosier RN, Schwarz EM, et al: PTHrP expression in chondrocytes, regulation by TGF-beta and interactions between epiphyseal and growth plate chondrocytes. Exp Cell Res 256:555-562, 2000.
19. Pösl M, Amling M, Neff L, et al: Coexpression of PTHrP and bcl-2 correlates with the degree of malignancy of chondrogenic tumors. J Bone Miner Res 11:S113, 1996.
20. Rosier RN, O'Keefe RJ, Teot LA, et al: P-Glycoprotein expression in cartilaginous tumors. J Surg Oncol 65:95-105, 1997.
21. Schipani E, Kruse K, Jüppner H: A constitutively active mutant PTH-PTHrP receptor in Jansen-type metaphyseal chondrodysplasia. Science 268:98-100, 1995.
22. Segre GS, Brown EM: Secretion, Circulating Heterogeneity, and Metabolism of Parathyroid Hormone. In Favus MJ (ed). Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism. Ed 3. Philadelphia, Lippincott-Raven 63-67, 1996.
23. Suva LJ, Winslow GA, Wettenhall RE, et al: A parathyroid hormone-related protein implicated in malignant hypercalcemia: Cloning and expression. Science 237:893-896, 1987.
24. Urena P, Kong XF, Abou-Samra AB, et al: Parathyroid hormone (PTH)/PTH-related peptide receptor messenger ribonucleic acids are widely distributed in rat tissues. Endocrinology 133:617-623, 1993.
25. Weir EC. Philbrick WM, Amling M, et al: Targeted overexpression of parathyroid hormone-related peptide in chondrocytes causes chondrodysplasia and delayed endochondral bone formation. Proc Natl Acad Sci USA 93:10240-10245, 1996.