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Volumn 5, Issue 5, 2002, Pages 466-471

Novel strategies in antifungal lead discovery

Author keywords

[No Author keywords available]

Indexed keywords

AMPHOTERICIN B; ANTIFUNGAL AGENT; CALMODULIN; CASPOFUNGIN; DNA; ERGOSTEROL; FK 506 BINDING PROTEIN; FLUCONAZOLE; FOSFOMYCIN; GALACTOSE; GENE PRODUCT; GLYOXYLIC ACID; HYBRID PROTEIN; ISOCITRATE LYASE; ITRACONAZOLE; MALATE SYNTHASE; MYCOPHENOLIC ACID; NUCLEOTIDE; NYSTATIN; OXIDOREDUCTASE; PHOSPHATIDYLINOSITIDE; POLYENE; PROTEASOME INHIBITOR; PROTEIN; RAPAMYCIN; SORBITOL; SYNTHETASE; TACROLIMUS; TRICARBOXYLIC ACID;

EID: 0036790072     PISSN: 13695274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1369-5274(02)00361-2     Document Type: Review
Times cited : (21)

References (37)
  • 2
    • 0036205767 scopus 로고    scopus 로고
    • Caspofungin: An echinocandin antifungal agent
    • Stone EA, Fung HB, Kirschenbaum HL: Caspofungin: an echinocandin antifungal agent. Clin Ther 2002, 24:351-377.
    • (2002) Clin Ther , vol.24 , pp. 351-377
    • Stone, E.A.1    Fung, H.B.2    Kirschenbaum, H.L.3
  • 3
    • 0035992113 scopus 로고    scopus 로고
    • Echinocandins: A new class of antifungal
    • Denning DW: Echinocandins: a new class of antifungal. J Antimicrob Chernother 2002, 49:889-891.
    • (2002) J Antimicrob Chernother , vol.49 , pp. 889-891
    • Denning, D.W.1
  • 5
  • 6
  • 8
    • 0343349053 scopus 로고    scopus 로고
    • Stanford Genome Technology Center: Candida albicans Genome Project. On World Wide Web URL: ftp://cycle.stanford.edu/pub/projects/candida
    • Candida albicans Genome Project
  • 10
    • 84907716781 scopus 로고    scopus 로고
    • Whitehead Institute: Neurospora crassa Database. URL: http://www-genome.wi.mit.edu/annotation/fungi/neurospora/
    • Neurospora crassa Database
  • 11
    • 85031447969 scopus 로고    scopus 로고
    • Department of Energy Joint Genome Institute: White Rot Genome Project. URL: http://www.jgi.doe.gov/programs/whiterot.htm.
    • White Rot Genome Project
  • 13
    • 34247366234 scopus 로고    scopus 로고
    • Whitehead Institute: Magnaporthe grisea Database. URL: http://www-genome.wi.mit.edu/annotation/fungi/magnaporthe/
    • Magnaporthe grisea Database
  • 14
    • 84886758659 scopus 로고    scopus 로고
    • Mouse Genome Sequencing Consortium: Ensembl Mouse Genome Server. URL: http://www.ensembl.org/Mus_musculus/stats/
    • Ensembl Mouse Genome Server
  • 16
    • 0034700103 scopus 로고    scopus 로고
    • A chemical genomics approach toward understanding the global functions of the target of rapamycin protein (TOR)
    • Chan TF, Carvalho J, Riles L, Zheng XF: A chemical genomics approach toward understanding the global functions of the target of rapamycin protein (TOR). Proc Natl Acad Sci USA 2000, 97:13227-13232.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 13227-13232
    • Chan, T.F.1    Carvalho, J.2    Riles, L.3    Zheng, X.F.4
  • 17
    • 0037178849 scopus 로고    scopus 로고
    • Screening the yeast 'disruptome' for mutants affecting resistance to the immunosuppressive drug, mycophenolic acid
    • Desmoucelles C, Pinson B, Saint-Marc C, Daignan-Fornier B: Screening the yeast 'disruptome' for mutants affecting resistance to the immunosuppressive drug, mycophenolic acid. J Biol Chem 2002, 277:27036-27044.
    • (2002) J Biol Chem , vol.277 , pp. 27036-27044
    • Desmoucelles, C.1    Pinson, B.2    Saint-Marc, C.3    Daignan-Fornier, B.4
  • 18
    • 0036124292 scopus 로고    scopus 로고
    • High-density cell microarrays for parallel functional determinations
    • Xu CW: High-density cell microarrays for parallel functional determinations. Genome Res 2002, 12:482-486.
    • (2002) Genome Res , vol.12 , pp. 482-486
    • Xu, C.W.1
  • 19
    • 0035940494 scopus 로고    scopus 로고
    • A genome-wide screen in Saccharomyces cerevisiae for genes affecting UV radiation sensitivity
    • Birrell GW, Giaever G, Chu AM, Davis RW, Brown JM: A genome-wide screen in Saccharomyces cerevisiae for genes affecting UV radiation sensitivity. Proc Natl Acad Sci USA 2001, 98:12608-12613.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 12608-12613
    • Birrell, G.W.1    Giaever, G.2    Chu, A.M.3    Davis, R.W.4    Brown, J.M.5
  • 23
    • 0035811478 scopus 로고    scopus 로고
    • The glyoxylate cycle is required for fungal virulence
    • Lorenz MC, Fink GR: The glyoxylate cycle is required for fungal virulence. Nature 2001, 412:83-86.
    • (2001) Nature , vol.412 , pp. 83-86
    • Lorenz, M.C.1    Fink, G.R.2
  • 24
    • 0035966045 scopus 로고    scopus 로고
    • DNA array studies demonstrate convergent regulation of virulence factors by Cph1, Cph2, and Efg1 in Candida albicans
    • Lane S, Birse C, Zhou S, Matson R, Liu H: DNA array studies demonstrate convergent regulation of virulence factors by Cph1, Cph2, and Efg1 in Candida albicans. J Biol Chem 2001, 276:48988-48996.
    • (2001) J Biol Chem , vol.276 , pp. 48988-48996
    • Lane, S.1    Birse, C.2    Zhou, S.3    Matson, R.4    Liu, H.5
  • 26
    • 0037172948 scopus 로고    scopus 로고
    • Transcriptional response of Saccharomyces cerevisiae to DNA-damaging agents does not identify the genes that protect against these agents
    • Birrell GW, Brown JA, Wu HI, Giaever G, Chu AM, Davis RW, Brown JM: Transcriptional response of Saccharomyces cerevisiae to DNA-damaging agents does not identify the genes that protect against these agents. Proc Natl Acad Sci USA 2002, 99:8778-8783.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 8778-8783
    • Birrell, G.W.1    Brown, J.A.2    Wu, H.I.3    Giaever, G.4    Chu, A.M.5    Davis, R.W.6    Brown, J.M.7
  • 30
    • 0034680167 scopus 로고    scopus 로고
    • Molecular mechanisms that confer antibacterial drug resistance
    • Walsh C: Molecular mechanisms that confer antibacterial drug resistance. Nature 2000, 406:775-781.
    • (2000) Nature , vol.406 , pp. 775-781
    • Walsh, C.1
  • 31
    • 0035793383 scopus 로고    scopus 로고
    • Bakers' yeast, a model for fungal biofilm formation
    • Reynolds TB, Fink GR: Bakers' yeast, a model for fungal biofilm formation. Science 2001, 291:878-881.
    • (2001) Science , vol.291 , pp. 878-881
    • Reynolds, T.B.1    Fink, G.R.2
  • 32
    • 0034754699 scopus 로고    scopus 로고
    • Development of Saccharomyces cerevisiae as a model pathogen. A system for the genetic identification of gene products required for survival in the mammalian host environment
    • Goldstein AL, McCusker JH: Development of Saccharomyces cerevisiae as a model pathogen. A system for the genetic identification of gene products required for survival in the mammalian host environment. Genetics 2001, 159:499-513.
    • (2001) Genetics , vol.159 , pp. 499-513
    • Goldstein, A.L.1    McCusker, J.H.2
  • 33
    • 0033597797 scopus 로고    scopus 로고
    • An adhesin of the yeast pathogen Candida glabrata mediating adherence to human epithelial cells
    • Cormack BP, Ghori N, Falkow S: An adhesin of the yeast pathogen Candida glabrata mediating adherence to human epithelial cells. Science 1999, 285:578-582.
    • (1999) Science , vol.285 , pp. 578-582
    • Cormack, B.P.1    Ghori, N.2    Falkow, S.3
  • 34
    • 0033920913 scopus 로고    scopus 로고
    • Signature-tagged and directed mutagenesis identify PABA synthetase as essential for Aspergillus fumigatus pathogenicity
    • 2900
    • Brown JS, Aufauvre-Brown A, Brown J, Jennings JM, Arst H Jr, Holden DW: Signature-tagged and directed mutagenesis identify PABA synthetase as essential for Aspergillus fumigatus pathogenicity. Mol Microbiol 2900, 36:1371-1380.
    • Mol Microbiol , vol.36 , pp. 1371-1380
    • Brown, J.S.1    Aufauvre-Brown, A.2    Brown, J.3    Jennings, J.M.4    Arst H., Jr.5    Holden, D.W.6
  • 35
    • 0035102985 scopus 로고    scopus 로고
    • Identification of virulence mutants of the fungal pathogen Cryptococcus neoformans using signature-tagged mutagenesis
    • Nelson RT, Hua J, Pryor B, Lodge JK: Identification of virulence mutants of the fungal pathogen Cryptococcus neoformans using signature-tagged mutagenesis. Genetics 2001, 157:935-947.
    • (2001) Genetics , vol.157 , pp. 935-947
    • Nelson, R.T.1    Hua, J.2    Pryor, B.3    Lodge, J.K.4
  • 36
    • 0034754163 scopus 로고    scopus 로고
    • A yeast sensor of ligand binding
    • Tucker CL, Fields S: A yeast sensor of ligand binding. Nat Biotechnol 2001, 19:1042-1046.
    • (2001) Nat Biotechnol , vol.19 , pp. 1042-1046
    • Tucker, C.L.1    Fields, S.2
  • 37
    • 0037061492 scopus 로고    scopus 로고
    • Dissecting glucose signalling with diversity-oriented synthesis and small-molecule microarrays
    • Kuruvilla FG, Shamji AF, Sternson SM, Hergenrother PJ, Schreiber SL: Dissecting glucose signalling with diversity-oriented synthesis and small-molecule microarrays. Nature 2002, 416:653-657.
    • (2002) Nature , vol.416 , pp. 653-657
    • Kuruvilla, F.G.1    Shamji, A.F.2    Sternson, S.M.3    Hergenrother, P.J.4    Schreiber, S.L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.